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Results for “INTESTINAL DISEASES”

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At least 109 records · Page 6Linked to original sources
PubMed2002

Vero cytotoxin-producing Escherichia coli in a study of infectious intestinal disease in England.

An investigation of infectious intestinal disease in England included examination of feces for Vero cytotoxin-producing Escherichia coli (VTEC). Using DNA probe hybridization 27 VTEC strains were identified, 12 were from cases, and of these three belonged to serogroup O157. The remaining 15 strains were isolated from controls. The strains were confirmed biochemically as E. coli, they were serotyped and characterized according to their toxin production, the presence of sequences encoding intimin (eae) and enterohemolysin was determined and resistance to antimicrobial agents was determined. Six of the nine cases with non-O157 VTEC were less than 16 years old, only two of the 15 controls were under 16. Infection with more than one micro-organism was also considered.

Adolescent↗
PubMed1986

Diagnosis of Clostridium difficile-associated intestinal disease.

Toxigenic Clostridium difficile is the major cause of antimicrobial agent-associated pseudomembranous colitis and is the etiological agent of approximately 30% of cases of nonspecific colitis and diarrhea (without colitis) induced by antimicrobial agents. In addition, C. difficile has been implicated in certain intestinal diseases not related to prior antimicrobial administration. C. difficile has been reported to be one of the most common enteropathogens isolated from stool specimens submitted to hospital laboratories. Thus, diagnosis of C. difficile-associated intestinal disease should now be routinely performed in diagnostic clinical laboratories. The diagnosis of C. difficile-associated intestinal disease relies on the demonstration of either the organism or the toxin(s) in stool specimens or antibody response in serum to the toxin(s). Several selective medium are available for the recovery of C. difficile from stool specimens. The toxin(s) of C. difficile can be demonstrated using a variety of techniques, including biological assays as well as immunological assays. This article will review the techniques currently available to aid in the diagnosis of C. difficile-associated intestinal disease.

Anti-Bacterial Agents↗
PubMed1998

Immunoproliferative small intestinal disease in South India: a clinical and immunomorphological study.

Immunoproliferative small intestinal disease (IPSID), a proliferative disorder affecting the intestinal immune system, has only been reported sporadically in India. Fifteen patients with malabsorption syndrome who were diagnosed to have IPSID were included in this study. Mucosal biopsies from all patients, full thickness surgical biopsies from 10 and autopsy material from four patients were examined by light microscopy and immunohistochemistry. The patients were predominantly young (aged 16-36 years) and male (13 of 15). Diarrhoea, weight loss, vomiting and abdominal pain were the major symptoms. The upper small bowel was involved in all cases. Involvement of large bowel was detected antemortem in three patients, but was found in all autopsied patients. Involvement of the stomach was noted in one patient at autopsy. Mesenteric lymph nodes were involved in all patients who underwent laparotomy. The plasmacytic infiltrate was uniformly positive for alpha-heavy chain, and either negative for light chain production or showed monotypic light chain production. Some of the blasts were also positive for alpha-heavy chain. Three patients died before therapy could be commenced. One patient with stage A disease is alive and clinically free of disease at 7 years. Of the remainder, there have been four long-term survivors with chemotherapy. Immunoproliferative small intestinal disease occurs in southern India and has characteristics similar to that in other parts of the world. Early diagnosis may improve outcome in this disease.

Adolescent↗
PubMed1980

Urological complications in malignant and inflammatory intestinal diseases.

Secondary involvement of the ureter or urinary bladder in inflammatory and malignant diseases of the intestine is described with case reports and documented by figures. With involvement of the bladder wall, intractable dysuria or later pneumaturia and fecaluria arises. The symptoms from the intestine are masked by urological symptoms. If the intestinal process leads to a disease of the ureter, urological pathology is mostly limited to urographic findings; symptoms are circumscribed. However, the ureteric wall is usually already irreparably damaged.

Adult↗
PubMed1999

[Biopsy differential diagnosis of non-cancerous small intestinal diseases].

Both pathologists and gastroenterologists are one team working up patients with suspected small bowel diseases. Both have to try to recognize the various entities of disorders found in the small bowel. Some diseases, such as Whipple's disease, are histologically easily recognized by their specific changes. Others, however, show unspecific histological changes and may only be recognized by a certain pattern of inflammatory infiltration of the mucosa and/or by architectural changes. In the present paper giardiasis with its diagnostic trophozoites, Crohn's disease and celiac disease with their typical inflammation and mucosal architecture and their differential diagnoses are discussed. A modified Marsh classification is given, which allows to report the various types of celiac lesions more precisely. Furthermore, the variations found in the normal mucosa are presented. In particular, the presence of lymphocytes and plasma cells in the lamina propria is shown to be a part of the mucosa associated lymphatic tissue (MALT). The importance of giving a clear statement on the etiology of the disease whenever possible is stressed.

Biopsy↗