Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Forensic Pathology”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources

Subendocardial hemorrhages in forensic pathology autopsies.

In a review of 1,034 consecutive forensic autopsies, there were 43 cases that had a distinct zone of subendocardial hemorrhage in the septal wall of the left ventricle. Cases in which there was direct injury to the heart or cardiac resuscitation were not counted. Of the 43 cases, 26 (60%) died of head injuries. Other causes of death were drug or chemical intoxication (14%) and abdominal injuries (12%); miscellaneous causes accounted for 14%. The time between injury and death varied considerably; in 13 cases (30%), the interval was < 1 h. Drugs and/or alcohol were not factors in the appearance of subendocardial hemorrhage, unless the drug itself caused death. Among the drug- or chemical-related fatalities, there were four cases of cocaine overdose with subendocardial hemorrhages. The results of this study are consistent with the hypothesis that cardiac lesions secondary to noncardiac injuries, particularly head injuries, are mediated by hypersecretion of catecholamines. Previous studies have shown significant cardiac decompensation due to noncardiac injuries, and it is likely that the cardiac lesions are part of the mechanism of death. The secondary cardiac lesions are also important for heart transplantation; catecholamine-mediated cardiac damage following head injury or shock may adversely affect performance of the transplant in the recipient.

Autopsy↗

[Research evolvement of postmortem diagnosis of early myocardial infarction in forensic pathology].

The cardiac sudden death occupies primacy among the cause of death in adult. Myocardial infarction is one of the main mechanisms of sudden death of coronary heart disease. Because of early myocardial infarction happened abruptly and might die in a short time, and the typical or special changes in morphology is absent, so it is the focus of medico legal research forensic fulfill all long. This paper reviewed the characters of myocardial infarction, applications and limits in forensic fields, and prospected feasibility of new clinical markers in forensic practice, and expected to enhance accuracy of postmortem diagnosis in MI.

Adult↗

Black oesophagus: a rare disorder with potentially fatal outcome. A forensic pathological approach based on five autopsy cases.

Black oesophagus is a rare pathological condition of unknown aetiology characterised by a full length, circumferential black discolouration of the entire oesophageal mucosa. The disease is sporadically encountered during upper gastrointestinal endoscopy. We used conventional histology, enzyme histochemistry and immunohistology to examine five autopsy cases (four males, one female; age range 43-86 years) of black oesophagus. On microscopical examination, the esophageal mucosa was entirely necrotic with demarcation by a leukocytic infiltrate in the upper submucosa. This infiltrate was dominated by neutrophilic granulocytes and scattered macrophages lacking haemosiderin deposits, placing the noxious mucosal injury in a time frame of approximately 24-72 h prior to death. Black oesophagus was established as the immediate cause of death in one case due to desanguination from the oesophagus and significantly contributed to the fatal outcome in a second case. Apart from a history of chronic alcohol consumption in four cases, no other pre-existing pathological or debilitating conditions could be established. The remarkably consistent pathomorphological picture of the disease seems to be the result of impaired microcirculation of the oesophageal mucosa due to prolonged hypotension of variable aetiology. The diagnosis of black oesophagus requires exclusion of other causes such as ingestion of caustic materials and should be based on histological examination.

Adult↗

[The application of radiological imaging in the forensic pathology about cervical part].

Multislice spiral computed tomography (MSCT) and magnetic resonance imaging (MRI) are useful to analyze cervical injury. Especially in injury of skeleton and soft tissue, it has equal value with conventional autopsy. Even they can reparation some shortcoming consisted in the cervical part autopsy. In some difficult postmortem examination of decomposed, charred or highly infectious cadavers and in some religion country, they should be a useful alternative way to examine injury in cervical part of cadaver such as mechanical asphyxia, whiplash injury, vertebra injury, or vascular injury.

Asphyxia↗

Gastric mucosa lesions in drowning: its usefulness in forensic pathology.

In a retrospective study of 52 autopsy cases of drowning fatalities, death circumstances, macroscopical and histological findings of the stomach mucosa were carefully studied. Results were compared with a control group, composed by 80 cases of different kinds of asphyxia (hanging, chocking and suffocation), skull injuries, sudden cardiac death and poisonings. The spectrum of gastric lesions observed during autopsy in drowning group, are presented. Stomach mucosa tears were found in 21.1% of the cases of drowning, preferably on fundus (54.5%). The control group does not show similar lesions. The physiopathological mechanism of its production, are also discussed. On sight of these results, it is concluded that the macro and microscopical examination of the stomach could be useful as an adjunct procedure for drowning diagnosis. The presence of gastric mucosa lesions has an intravital significance and could be correlated with other anatomical or histological signs of drowning for the diagnosis. In every case, necropsic examination must be carried out as soon as possible in order to avoid putrefactive artifacts.

Adolescent↗