Cortical atrophy and air encephalography: a clinical and radiological study.
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Isotope and neuroradiological methods were evaluated in the diagnosis of 491 surgically confirmed cerebral tumours seen between 1966 and 1973 (July). They were analysed in terms of region, type and size. The accuracy of various techniques was investigared and their value when used in isolation and in combination with other methods was calculated.
Using a two-dimensional sector-scanner the brains of 642 preterm and term infants between 28 weeks of gestation and 12 months of age were examined for the incidence of a cavum septi pellucidi (CSP) and a cavum Vergae (CV). In 100 out of 642 infants we saw a CSP. The highest incidence (52%) was found among the infants of very low gestational age (-33 weeks) within the first seven days of life. After the second month the incidence decreases rapidly (only 1% in infants - months). We saw a CV only in combination with a CSP, less frequent, however, than a CSP alone (26 out of 642 infants): the incidence was 33% in infants of very low gestational age (-33 weeks) within the first seven days of live, only 4% in term neonates and 0% after the second month of life. Finally, the rupture of a septum with CSP and CV by stretching forces is demonstrated in an infant with progressive hydrocephalus. The data of this paper contribute to the knowledge of the morphological development of the normal fetal and newborn brain.
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UNLABELLED: Pyridoxine-dependent seizures are rare in newborn infants, although recent data suggest that the prevalence probably is underestimated. In all newborn infants with recurrent epileptic seizures the general recommendation is to administer pyridoxine and simultaneously record an electroencephalogram (EEG). CONCLUSION: One infant with pyridoxine-responsive seizures and another with pyridoxine-dependent seizures had different electroclinical responses on amplitude-integrated EEG monitoring (aEEG) when pyridoxine was administered.
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