Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Data Interpretation, Statistical”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMed2000

Genomic organization of the human metabotropic glutamate receptor subtype 3.

In this study, the genomic organization of the human metabotropic glutamate receptor subtype 3 (mGluR3) gene has been determined. We have identified two transcription initiation sites and the polyadenylation signal by using 5'-rapid amplification of cDNA ends (RACE) and 3'-RACE, respectively. The exon/intron organization of the human mGluR3 gene revealed the presence of 6 exons separated by 5 introns. The size of introns varied from 10.4 to 120 kbp that contained consensus sequences for repetitive elements such as Alu and long interspersed elements. A putative promoter region flanking the 5' sequence of exon 1 was identified by computer-aided analysis. The putative promoter region was characterized by the presence of a CAAT and GC box, and the absence of a TATA box or CpG islands. Several putative binding sites for transcription factors were also identified. In addition, we have isolated, from a mouse genomic library, part of the mouse mGluR3 gene and found it to correspond to exon 2 in the human mGluR3 gene. The mouse mGluR3 gene was then mapped by fluorescent in situ hybridization analysis to chromosome 5qA2.

Animals↗
PubMed1999

Self-organizing map (SOM) of space acceleration measurement system (SAMS) data.

In this paper, space acceleration measurement system (SAMS) data have been classified using self-organizing map (SOM) networks without any supervision; i.e., no a priori knowledge is assumed regarding input patterns belonging to a certain class. Input patterns are created on the basis of power spectral densities of SAMS data. Results for SAMS data from STS-50 and STS-57 missions are presented. Following issues are discussed in details: impact of number of neurons, global ordering of SOM weight vectors, effectiveness of a SOM in data classification, and effects of shifting time windows in the generation of input patterns. The concept of 'cascade of SOM networks' is also developed and tested. It has been found that a SOM network can successfully classify SAMS data obtained during STS-50 and STS-57 missions.

Acceleration↗
PubMedDate not supplied

Systematic reviews of interpretive research: interpretive data synthesis of processed data.

This paper discusses the synthesis of qualitative data during the systematic review of interpretive research. Current approaches to data synthesis can be broadly classified as either descriptive or interpretive. Descriptive data synthesis is achieved through narrative and tabulation. While a number of different terms have been used, interpretive synthesis is achieved through processes similar to those used by primary interpretive researchers. However, there has been only limited professional discussion and debate of this issue and existing methods are in need of further investigation and the validity and usefulness of the product of this synthesis examined.

Data Interpretation, Statistical↗
PubMed1991

Translating mainframe computer data to spreadsheet format.

The translation of mainframe-stored information in ASCII into spreadsheet format for use in Lotus 1-2-3 is explained. Details are presented on how to use the Data Parse command to create a translation template that tells Lotus 1-2-3 how to interpret a file written in ASCII. Lotus 1-2-3 can also translate some files in formats other than ASCII. It can translate files in the Data Interchange Format directly into its own format. Translating mainframe computer data into spreadsheet format is relatively simple and obviates the rekeying of those data.

Computers, Mainframe↗
PubMed1990

Interlaboratory quality assurance program.

The Coulter Interlaboratory Quality Assurance Program (IQAP) analyses data from several thousand haematology laboratories which use Coulter haematology controls (4C). Such peer group analyses are done at monthly intervals. These analyses compare the individual laboratory's performance with other laboratories using the same lot(s) of control cells on the same instruments. The data receipt and peer analysis methods are outlined using flow charts which describe the process.

Clinical Laboratory Techniques↗
PubMedDate not supplied

Computer-based data entry for nurses in the ICU.

Efforts are being made to improve the efficiency and quality of care in intensive care units (ICUs) at Latter Day Saints Hospital. The ICUs have been computerized, and the collection, storage, and presentation of patients' data have been improved. Nurses use computers for entering clinical data and plans for nursing care, and the effects of these changes on the work patterns of nurses in the ICU have been evaluated. Contrary to our expectation, our studies showed a decrease in the proportion of time that nurses spent in direct patient care (from 49.1% to 43.2%) and an increase in the proportion they spent entering clinical data (from 18.2% to 24.2%) after computerization. These changes, however, were attributed to a decrease in the severity of patients' illnesses, rather than the availability of the computer. There was no measurable difference in the proportion of time spent at other nursing activities.

Data Interpretation, Statistical↗
PubMed1989

The science of public health surveillance.

Improved public health surveillance can lead to earlier implementation of prevention and control measures. Better surveillance data lead to a more rational establishment of priorities. More timely and accurate data facilitate earlier epidemic detection and control. With better surveillance data, the impact of intervention activities and other public health programs can be evaluated more accurately. In this paper we describe how to improve the science of surveillance in terms of data collection, analysis, and dissemination and its application to public health practice. We then discuss the potential benefits and costs of such efforts and suggest methods for evaluating alternative approaches. The argument for science in surveillance, on the other hand, may be subject to excess. Surveillance is not an end unto itself, but rather a tool. This tool should be refined and modified to adapt to the goals of a particular public health program. It is the development of methods to apply creative ideas to surveillance, and the rigorous assessment of the process, that will benefit from the application of scientific principles.

Data Interpretation, Statistical↗
PubMed1995

Delivery of hepatitis B immunisations in a selection of computerised general practices.

AIM: To assess the value of computerised general practices in providing information concerning the delivery of hepatitis B immunisation. METHODS: Hepatitis B immunisation data from August 1990 to June 1991 were collected from 27 general practices participating in a sentinel network. RESULTS: The study identified significant limitations in the use of data from computerised general practices for estimating hepatitis B immunisation coverage. While an accurate coverage figure could not be estimated, the results did suggest that hepatitis B coverage for three doses was at least 59.5% and that its use was very similar to the triple vaccine and measles/MMR for the third dose. Hepatitis B immunisation delivery outside the desirable time periods was common at 44%, suggesting a fairly disrupted immunisation schedule for many children. CONCLUSIONS: The relatively infrequent delivery of hepatitis B vaccine at the same time as other vaccinations may reflect provider concern about administering multiple injections at the same visit. Further improvement in the collection of data by computerised practices is necessary before the full value of this data source can be realised. Improvements in reminder/recall systems would improve the efficiency with which hepatitis B immunisation is delivered.

Child, Preschool↗
PubMed1994

Evaluating the accuracy of transcribed computer-stored immunization data.

OBJECTIVE: To evaluate the accuracy of immunization records transcribed into a computer-based immunization tracking system and to assess factors that contribute to inaccurate or incomplete immunization record keeping. DESIGN: Computer-stored immunization records were analyzed for 2098 children up to 2 years of age at the time of their most recent well-child visit to the UCLA Children's Health Center over a 12-month period. For children whose immunizations were not up to date, the computer-stored records were analyzed for sources of inaccuracy by comparison with the handwritten records from which the computer-stored data were transcribed. RESULTS: An underimmunization rate of 22.5% (472 of 2098) was observed based on analysis of the computer-stored records. Comparison of the computer-stored and handwritten records revealed an overall transcription error rate of at least 10.2%. In addition, 38.4% of these apparently underimmunized children had received unrecorded immunizations from providers outside UCLA. When transcription errors were corrected and other available sources of immunization data were taken into account, the estimated rate of underimmunization decreased from 22.5% to 10.9%. CONCLUSION: Unavoidable inaccuracies can diminish the utility of the data recorded in an immunization tracking system. Some inaccuracies are related to the process of transcription, but failures to record and communicate immunization data consistently also contribute to the inaccuracy of computer-stored immunization records.

Child Health Services↗
PubMedDate not supplied

Characteristics of infants who undergo neonatal autopsy.

To identify factors associated with the performance of a neonatal autopsy, we surveyed autopsy practice patterns in a tertiary care neonatal intensive care unit for 1 year. After 56 neonatal deaths, 33 (59%) autopsies were performed. We used multivariable analysis to compare the clinical and demographic characteristics of infants who had an autopsy with those who did not. We found two variables to be negatively correlated with having an autopsy performed: birth asphyxia (p < 0.05) and Medicaid coverage (p < 0.05). Early neonatal death (< or = 2 days of age) was not correlated with lack of an autopsy. Pulmonary hypoplasia occurred more often in the group having autopsy. However, only birth asphyxia was significantly correlated with lack of an autopsy after adjusting for other variables in the analysis. The primary cause of death was not associated with performance of an autopsy. We found no significant association between consent for autopsy and the characteristics of the physician requesting it. These data suggest that the infant's socioeconomic status and diagnosis may influence parental consent for autopsy. There may be other characteristics of physicians who request it, parents who consent, or other socioeconomic factors influencing consent for the neonatal autopsy.

Adult↗
PubMed1997

[Structure and negative sequelae of medical errors in care for angina pectoris].

12 cardiologists trained as experts in assessment of medical care quality (MCQ) made a computer-assisted expertise of the care rendered to 110 anginal patients. Of these 68 patients had angina of effort (AE) and 42 had unstable angina (UA). This made up 10% of annual number of anginal patients treated in the cardiological clinic in 1996. Medical errors were of the same type in both the groups. Inadequate collection of information, erroneous diagnosis, treatment, continuity occurred in 50, 30, 15 and 5% of all the errors, respectively. Negative effects of the errors were mild (less seriously suffered AE patients), but led to waste of health service resources.

Angina Pectoris↗