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At least 109 records · Page 6Linked to original sources
PubMed1991

[Long time results of the Sandwich-technique for mandibular alveolar ridge augmentation].

During six years twenty-five patients have been operated upon using a "sandwich technique" for mandibular alveolar ridge augmentation. This technique was advocated by Schettler in 1974. In 3 cases, autologous rib cartilage was used, in 20 Cases an autologous transplant from the iliar crest and in two cases, autologous "cialit" conserved bone chips were inserted. All transplants healed without complications and less resorption was found in all transplants at the late follow-up examinations.

Alveolar Ridge Augmentation↗
PubMed1990

A scanning electron-microscopic study of different tympanic grafts.

The surface architecture of dried temporalis fascia autografts and preserved tympanic allografts was investigated by scanning electronmicroscopy. During the storage in formaldehyde-cialit solutions the outer epithelial as well as the inner mucosal layer of tympanic allografts are progressively detached, and finally the lamina propria with outer radial and inner circular fiber arrangement remains. Due to dehydration phenomena irregular "crater-like" defects, surrounded by an amorphous structure, appear in dried fascia autografts. While a real lamina propria graft may induce migration and differentiation of the host's canal wall epithelium into a specific tympanic epithelium, one may imagine epithelial spreading toward the middle ear along the observed defects in dried fascia grafts. This latter observation gives new evidence for the immigration cholesteatoma theory.

Fascia↗
PubMed1990

[Behavior on de-epidermized human skin of unspecified reconstituted collagen tissue].

The aim of our study was to assess the behaviour of a despecified collagen tissue laid on desepidermized human skin (taking area of skin graft). The collagen tissue was prepared according to Bell's method. The collagen was latticed, contracted by fibroblasts, chemically treated (formaldehyde or glutaraldehyde) to stabilize the fibrils and then despecified by cialit treatment. This tissue laid on superficial, non infected wounds very rapidly took a necrotic appearance and was totally lysed after 10 to 12 days without any modification of the healing course. No bacterial infection was observed. Histological and ultrastructural studies showed desorganization of collagen fibre bundles and tissue invasion by inflammatory cells. Circulating antibodies to collagen were absent at day 30. This model lacks interest as a substitute for superficial tissue replacement, but a healing function could be assigned to its high chemotactic power for polynuclears and macrophages and should allow its use in cases of deep tissue loss.

Aged↗
PubMed1985

[Vascularization and resorption of different supporting tissues by the greater omentum in the formation of compound microvascular transplants].

In former investigations the author described the use of omentum majus in building microsurgical compound island flaps employing supporting tissue. Now different kinds of hard tissue, such as autogenous bone and cartilage, allogenous bone and cartilage (preserved by Cialit-solution), Teflon-Fluorocarbon Polymer (Proplast) and tri-calcium phosphate were presented in omentum-sandwich flaps in a histological investigation. We paid special attention to resorption and vascularisation of hard tissue. Allogenous cartilage grafts or artificial materials like Proplast were the most suitable to put into a compound omental island flap. There was good vascularisation with no resorption, especially with Proplast.

Animals↗
PubMed1977

[Surgical treatment of old alveolar process fractures for the rehabilitation of mastication].

Surgical therapy of old fractures of the alveolar ridge is indicated if masticatory disturbances exist or are expected. Bony fragments of the alveolar ridge which carry teeth and are consolidated in dislocation are osteotomized, repositioned and fixed by dental splints for more than eight weeks. The guidelines for segmental and en bloc osteotomy in orthodontic surgery are applicable. Defects of the alveolar ridge are treated by vestibuloplasty or reconstructive surgery. It is also possible to combine the two methods. For the reconstruction of the alveolus, recently almost exclusively homologous transplants preserved in Cialit are used. Following reconstruction, additional vestibuloplasty may be carried out three months after the transplantation of bone or cartilage.

Alveolar Process↗
PubMed1988

[The hardness and osseous structure of preserved ear ossicles].

The mechanical rigidity (breaking strength) of normal human ossicles, preserved with cialit and formalin, was studied in a tension compression testing machine. The bony structure of the ossicles before and after crushing was examined via high-grade magnifying radiography. With this new technique, minute bony details of the ossicles, which up to now could be demonstrated only histologically--consequently destroying the object--can be visualised without inflicting any changes to the ossicle. The different preservation methods had no effect on the structure or the mechanical strength of the ossicles. The fracture lines were distributed at random, with no preferential direction. In further experiments, defects in the ossicles' surfaces, which were cut with diamond burrs, were investigated radiographically and with a scanning electron microscope. The compressed bone dust seals up the opened marrow spaces. This reduces bone resorption significantly, as could be demonstrated with removed ossicular transplants similarly prepared, with had been implanted several years ago. The high grade radiographic magnification revealed that several ossicles which were removed during typical middle ear operations, were covered with metallic powder, originating from the intra-operative contact of the burr with the metallic suction tube. The 10% nickel component of the alloy may cause problems in patients with known nickel allergy, considering the intensive contact with the vast surface of the disseminated metallic dust particles.

Ear Ossicles↗
PubMed1986

[Use of allogeneic septal cartilage in the correction of saddle nose].

It is reported about the intraseptal implantation of allogeneic cartilago quadrangularis for the correction of saddle nose in the case of eleven patients. The indication for the implantation were non sufficient residuals of the behind septum for a substitution plastic. The sagging of the noses was caused by iatrogenic in 6 and traumatic influences in 5 cases. The conservation of the septal cartilage was carried out in Cialit 1:5000. All the septa healed in without any reaction and obtained satisfactory functional and cosmetic results.

Cartilage↗
PubMed1987

[Antigenicity of the auricular cartilage and its modification by vital preservation. 1. Xenogeneic transplantation of human auricular concha cartilage to the rabbit].

By means of xenotransplantation of human auricular cartilage to rabbits tests were carried out to see, if antigenicity is reduced through storing elastic cartilage either in a nutrient solution (Ham F 12) at 4 degrees C above zero or in a tissue culture (Ham F 12 + 10% serum of a calf-foetus) at 37 degrees C above zero, and if vital preservation prevents degeneration- and resorption processes of cartilage. The results were compared to transplants of fresh, not treated cartilages, and those preserved with cialit and merthiolate. It turned out that these vital preservation methods seem to cause an extensive loss of the cartilages characteristic qualities and that they keep degeneration- and resorption processes at a minimal level. Big differences between storage in nutrient solution and tissue culture could not be observed.

Animals↗
PubMed1985

[Reduction of radical cavities by homologous cartilage chips].

The article reviews, first of all, the common obliteration methods of radical cavities. This is followed by a description of the author's own technique which has been practiced for the last 13 years. This method employs preserved (Cialit solution 1:5000) homologous septal cartilage chips, shaped into small cubes of 3-4 mm. size. The chips are implanted in obscure districts (apical mastoid, sinus dura angle) of radical cavities for primary or secondary (old cavities) partial obliteration, as shown in Figs. 1 and 2. Crushed homologous septal cartilage plates and temporal muscle fascia are placed additionally on the chips. The effect is the construction of a small, easy-care cavity, which can be appreciated at a glance. Statistical results of 314 cases (170 cases of primary obliteration, 144 old cavities) are presented. Chips in cavities are well tolerated. Chips were partially rejected in 13 cases only, whereas in 3 cases they were completely rejected. A permanent dry cavity and dry ear was achieved in 86% of the cases. Cholesteatoma recurred in 5 cases. The homologous cartilage technique is contraindicated in fistulas on the labyrinth or fenestra, as well as in exposed facial nerve or dehiscence of the facial nerve canal, in case of healed fistula of the dura, and in dissection of the sinus sigmoideus. In these cases, autologous cartilage (tragus, cavum conchae) must be implanted. One of the most important advantages of this method is that there is no crumpling up of the obliterated areas and no retractions over a longer period of time, compared with other relevant techniques (i.e., pedicled subcutis muscle grafts or free tissue flaps).

Cartilage↗
PubMed1977

[The histological changes in cartilage (incus) in the middle ear after conservation--an animal study (author's transl)].

This study demonstrates the histological changes of incus cartilage after transplantation into the middle ear space of rabbits. Conservation was performed by deep-freezing, lyophilisation in connection with gamma-irradiation, or with Cialit in differing dilutions. Controlled deep-freezing at about -196 degrees C and uncontrolled deep-freezing at about -20 degrees C guarantee after transplantion the survival of some vital chondrocytes. The other methods of conservation cause death of all chondroxytes. Cartilage prepared by these methods demonstrates potential for new bone formation. Only the xenogenetic cartilage loses its osteogenic potential after treatment by lyophilisation in connection with gamma-irradiation. The histological value of the transplant differs according to the method of conservation. No special tendency for resorption or inflamatory reactions could be seen.

Animals↗
PubMed1977

[Radio-anatomical study of the arteries of the hand. Anastomoses (radiological incidences). Digital vascularization (apropos of 25 anatomo-radiological preparations)].

METHOD: An original procedure is used for the specimens. The hands of fresh corpses preserved in a cialit solution are prepared by an injection of resin mixed with a leadsalt into the arteries. The accurate dissection of the hand's arteries is compared to the X rays. RESULTS: 1) Palmar arci are rare. We found an arcus palmaris superficialis in 10% and an arcus palmaris profundus in about 50% of the specimens. To avoid a misinterpretation of X rays, three incidences were used (one full-face and two oblique incidence: a transversal one at 15 degrees and a vertical or longitudinal one at 30 degrees). 2) All fingers receive arteries of double origin in 80% of the cases. Only in 20% of all cases, the thumb or the little finger have an exclusive vascularisation (radial for the thumb and ulnar for the little finger). 3) All digital anastomoses are dissected--Retrotendineous anastomoses are patent and large.

Angiography↗
PubMed1978

[A clinical study on allogenetic ossicle-implantation (author's transl)].

Here we report a first three years clinical experience with allogenetic ossicles in middle ear surgery. The several allogenetic implants in tympanoplasty type III are coordinated to symbolic abbreviations for documentation. The technique and biology of Cialit-preservation is summarized. Findings and results vindicate the application of allogenetic ossicles outside large ENT hospitals too.

Cholesteatoma↗
PubMed1982

20 years of experience with homografts in ear surgery.

Since I introduced the homograft transplantation en bloc in 1959, more than 2,400 patients with chronic middle-ear inflammation and the conditions resulting from an old radical operation have been operated upon. Different kinds of chemical solution for the conservation of the homograft have been used, and experience has shown that the best solution is a combination of Cialit 1:5,000 and formaldehyde 4 per cent, pH. 7.2. The indications for a homograft transplant have to be very precise, and we have divided the indications into two groups: In the first group, belonging to routine ear surgery, we can use homograft fascia, perichondrium, dura, ossicles and cartilage in the same way as in autografts. The second group is indicated when a larger part of the middle ear is destroyed. The healing process and function of the middle ear after homograft transplantation depend on correct indications, on preparation of the middle ear, on the correct fitting of the transplant, and on careful treatment after the transplantation. By using homografts in routine surgery of the middle ear, the structural and functional results are equivalent to those of autografts. In the second group, in which a large part of the middle ear is destroyed, or in which the condition resulting from a radical operation is achieved by an immediate fresh operation on the middle ear, the healing and functional results are much better than with patients after an old radical operation.

Chronic Disease↗
PubMed1980

[Development of the vascularisation in ossicula trans- and implants (author's transl)].

The revascularisation in 30 rabbit incudes after autogenic transplantation and allogenic implantation as well as in 5 mallei of the calf after xenogenic implantation was investigated. Prior to allogenic implantation the ossicles had been treated in five different ways: 5 ossicles had been cooled down to - 20 degrees C or to - 196 degrees C respectively, 5 others had been treated with cialit (1:5000) and 5 had been freeze dried with subsequent gamma-irradiation. In the last five collectives during the process of revascularisation the sprouting tissue of the host follows the bony canaliculi of Havers. It either forms normal capillaries or it leads to a widening of the bony canaliculi of Havers; in this case capillaries with larger diameter predominate. In the ossicles after xenogenic implantation, however, a still persistent antigenic reaction causes a hyalinisation of the capillary walls with considerable reduction of their inner diameter.

Animals↗
PubMed1980

[Formation of new bone and bone destruction in preserved incus homografts. Histological examinations of implants from 100 patients (author's transl)].

103 tympanoplastic re-operations were done in 100 patients. 103 Cialit-preserved incus homografts were drawn out for histological examination, which were implanted in the mean two years before. The data of the course of the disease were correlated with the histological finding. All incus homografts showed the well known formation of new bone in a different amount. Moreover 50% showed already macroscopically signs of bone resorption. Distinct indications for defense reactions of the recipient against the devital incus homograft were detected.

Bone Resorption↗
PubMed1980

[The management of cervical tracheal stenosis (author's transl)].

In this paper the aetiology and the different surgical methods of management of laryngotracheal fibrotic stenoses are discussed and are compared with our own experiences. Between 1969 and 1978 47 patients with scar tissue stenoses, which in 30 included the cervical trachea, have been treated. For the isolated tracheal stricture not involving more than 6 tracheal rings segmented resection with end to end anastomosis produces excellent results. For combined laryngeal and tracheal stenosis complete anterior and posterior longitudinal dissection of the trachea and posterior longitudinal dissection of the trachea and cricoid cartilage together with stenting with a Silicone T tube is preferred. To strengthen the larger defects of the anterior wall Cialit preserved tracheal homografts are used.

Cricoid Cartilage↗
PubMed1979

[Results of heterologous tracheal transplants in animal experiments (author's transl)].

In the present study, 7 x 15 mm Cialit-preserved human tracheal segments were grafted to the tracheas of five 3-month old piglets. 72-120 days later, the animals were sacrificed and the grafts with proximal and distal control areas were removed. Tissues were then examined macroscopically and by light and scanning electron microscopy. We found that: (1) all grafts had taken well; (2) no animal suffered from clinical signs of respiratory obstruction or inflammation; (3) although luminal diameters of the tracheas increased from 8 mm to 22 mm, the size of the grafts remained unchanged but the resulting tracheal stenosis did not cause respiratory obstruction; (4) the graftet areas showed re-epithelialization. The nature of the re-epithelialization as well as the fate of the submucosa and tracheal cartilage will be reported in a subsequent publication.

Adult↗
PubMed1977

[Reconstructive surgery of the orbit and adjacent paranasal structures (author's transl)].

In reconstruction of the orbital floor, homograft lyophilised dura or cialit-stord rib cartilage are suitable, but the best materials are autologous cartilage or silastic or teflon. Autograft bone from the maxilla or rib is rarely used. The surgery of traumatic hypertelorism and the reconstruction of the medial angle of the eye after orbito-nasal fractures are described and illustrated. With complete destruction of the floor of the orbit, a fronto-temporal pedicled flap combined with auricular cartilage is recommended. In this way, the orbital floor and the lower eyelid can be reconstructed. The epithelial lining of the orbit can be developed from a pedicled flap of maxillary sinus mucus membrane.

Cartilage↗