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[Lysosomal enzymes in the neoplastic pathology of the uterine cervix. Study of acid phosphatase in the diagnostic test of vaginal secretions in patients with pre-invasive and invasive cancer of the uterine cervix. I. Methods and preliminary experiences].

Gomori's method was used in the detection of positive -- or negative -- phosphatase granulations and their intracellular locations in vaginal secretions from 10 normal women and 20 patients with cervical neoplasia in various stages. Positive-phosphatase granulations were absent in normal subjecta and those with advanced neoplasia, whereas mainly large and medium-sized paranuclear positive granulations were a prominent feature of epithelial cells from patients from state 0-ToNoMo carcinomas. Further details will be given in a second note.

Acid Phosphatase↗