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The electrical induction of callus formation and external skeletal fixation using methyl methacrylate for delayed union of open tibial fracture with segmental loss.

A case of delayed union of an open tibial fracture with segmental loss is presented in which electricity was applied to the bone defect through two screws that were connected to a methy methacrylate skeletal fixation device. The fracture developed electrically induced callus formation around the cathode, callus extended to the anode, and solid bony union ensued. External skeletal fixation using methyl methacrylate is convenient and is a suitable adjunct to electrical stimulation of fracture healing.

Adult↗

Fracture healing perspectives.

This paper reviews the sequence of histomorphologic changes that occur in and around a fracture site, and discusses recent concepts about the roles of the cells and bone matrical moieties in promoting specific cell transformations during the phases of callus tissue formation and consolidation of the bony cortex. Current knowledge about the roles of autocrine, paracrine, and endocrine polypeptide growth and transforming factors lends new perspectives about this classic problem in bone physiology.

Animals↗

[Effects of pulsing electromagnetic fields (PEMF) on the course of vertebral fusion callus. A histological study].

In this paper the findings concerning the effectiveness of PEMF on the evolution of the vertebral fusion callus are reported. The study has been carried on by preparing postero-lateral arthrodesis in the lumbar spinal tract in rats. In this tract the laminae have been decorticated, the articular processes prepared by decortication and removal of the articular cartilage, and the spinal processes removed and employed as osteoinductive material. The rats sacrificed after 4 and 8 weeks, show how the decorticated areas are clearly influenced from PEMF, an early appearance of the bony fusion callus is already evident in the treated group just after 4 weeks. Also the articular areas are influenced from PEMF but less markedly than the decorticated one; in these areas after 8 weeks the fusion callus is prevalently cartilaginous even if areas of calcification are detectable inside. This different behaviour can be explained with the absence of any form of spinal fusion by means of surgical tools.

Animals↗

Bone healing following two methods of non-rigid tibial osteotomy repair in the dog.

Bone healing was assessed after stabilisation of transverse tibial osteotomies in adult Beagles (n = 6) with intramedullary pins, in conjunction with modified Mennen clamp-on plates to counteract rotation. Post-operative return to full limb function was compared to that after use of a two-pin, uniplanar (Type I) external skeletal fixator and an intramedullary pin combination (n = 6). Additional external splinting was not used. The dogs were graded weekly after exercise, according to a functional performance grading scale. All of the clamp-on plates were well tolerated. Bony periosteal callus incorporated the crimp arms and the mean time required for full limb function was 7 weeks. The clinical performance of the dogs, with the external skeletal fixators and intramedullary pins, was consistently lower during the initial 4 weeks. Soft tissue swellings with pin-tract drainage occurred, but resolved following removal of the transcortical fixation pins. These dogs returned to full limb function with bony bridging callus after 8 to 9 weeks. Quantitative assessment of the bone activity, using sequential scintigraphy at weekly intervals, suggested consolidation of the callus 6 weeks after the operation for the clamp-on plate and pin combination, and at 7 weeks for the external skeletal fixator and pin combination.

Animals↗