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Results for “BLOOD LIPIDS”

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Glycemic optimization may reduce lipid peroxidation independent of weight and blood lipid changes in Type 2 diabetes mellitus.

The aim of this study was to determine the effect of diet-therapy on lipid peroxidation in patients with Type 2 diabetes mellitus (T2DM). Fifteen T2DM patients of both sexes, aged between 35-70 years, were given the diet suggested for patients with diabetes by the American Diabetic Association. This diet comprised 50-60% carbohydrate, 10-15% protein, 20-30% fat and about 35 g fiber was given for weight maintenance. Weight and body mass index did not change significantly during 8 weeks of study. Also, no statistically significant difference was observed in serum total cholesterol, triglycerides, LDL- and HDL-cholesterol from before to after dietary intervention. However, the levels of fasting blood sugar, HbA1c and malondialdehyde were lowered significantly after dietary intervention. It was concluded that glycemic optimization, independent of weight and blood lipid profile, through a well-designed diet is likely to be the most effective factor in reducing the process of oxidative stress in T2DM. This may have preventive implications for such diabetic complications as atherosclerosis.

Adult↗

[Breast cancer with low levels of blood lipids].

Double-bond lipids levels in blood were assessed in 113 breast cancer patients. The levels of double bonds in plasma lipids and red blood cells were found to be much higher than those in healthy females and cases of mastopathia cystica fibrosa. A correlation between tumor extension and insufficient levels of blood lipids was established. The double-bond levels were higher: (a) in blood lipids of inoperable cases as compared with surgical ones; (b) in cases of stage I-II tumor, as compared with stage III, and (c) in cases of unfavorable clinico-morphological factors. Blood lipids levels tended to be relatively higher in patients who survived a shorter period after examination. It is suggested that lipids insufficiency in blood may be used as an indicator of certain interrelationships between tumor and body at different stages of tumor process.

Adult↗

The impact of exercise training on blood lipids in older adults.

Increasing physical activity is often prescribed to improve blood lipids; however, the efficacy of exercise in improving blood lipids in older adults is not clear. The objective of this study was to examine the effects of different exercise modes on blood lipid levels in previously sedentary older adults engaging in a 16-week exercise intervention. One hundred thirty-one subjects (mean age 74.6+/-6 years) were randomly assigned to a resistance training group, aerobic walking group, combined exercise group, or nonexercising control group. Blood lipids were measured at baseline, 8 weeks, and postintervention. Exercise mode did not impact blood lipids. All groups had lower lipid levels over time. Total cholesterol, low- and high-density lipoprotein, and triglycerides were significantly lower. The decrease in all groups, including the controls, may be due to a seasonal effect in older adults that has been documented in younger individuals.

Age Factors↗

[Blood lipids].

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Coronary Disease↗

Aerobic physical fitness in relation to blood lipids and fasting glycaemia in adolescents: influence of weight status.

BACKGROUND AND AIMS: We explored the associations between aerobic physical fitness with blood lipids and a composite index of blood lipids and fasting glycaemia in adolescents, analysing possible interactions with weight status. METHODS AND RESULTS: Body mass index and aerobic physical fitness was measured in 2090 adolescents (1034 males and 1056 females) 13-18.5 years by using the 20-m shuttle run test. Plasma glucose, total, high density lipoprotein (HDL) and low density lipoprotein (LDL) cholesterol, triglycerides, apolipoprotein (apo) A-I, apo B-100 and lipoprotein(a) [Lp(a)] were measured in 460 of the 2090 subjects. After adjustment for confounding factors, a continuously distributed summary score for blood lipids and fasting glycaemia was significantly related to aerobic fitness in males (P=0.018) and females (P=0.045, from the 2nd to the 4th quartile of aerobic fitness). After adjustment for gender, age, sexual maturation and economic status, aerobic fitness was related to the composite index of blood lipids and glycaemia in both overweight and non-overweight adolescents (P< 0.05). However, for the same level of aerobic fitness, the composite index of blood lipids and glycaemia was significantly higher in overweight adolescents (P=0.001). After setting the minimal aerobic fitness standards to present a healthy lipid profile, about 50% of males did not reach such values. CONCLUSION: Our data suggest that both aerobic fitness and weight management are associated with a composite index of blood lipids and glycaemia in adolescents. Our study also provides the minimal levels of aerobic physical fitness associated with a favourable lipid profile in male adolescents, a new tool which should be adopted by schools as "aerobic fitness standards".

Adolescent↗