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The effect of treatment with gum Arabic on gentamicin nephrotoxicity in rats: a preliminary study.

In the present work we assessed the effect of treatment of rats with gum Arabic on acute renal failure induced by gentamicin (GM) nephrotoxicity. Rats were treated with the vehicle (2 mL/kg of distilled water and 5% w/v cellulose, 10 days), gum Arabic (2 mL/kg of a 10% w/v aqueous suspension of gum Arabic powder, orally for 10 days), or gum Arabic concomitantly with GM (80mg/kg/day intramuscularly, during the last six days of the treatment period). Nephrotoxicity was assessed by measuring the concentrations of creatinine and urea in the plasma and reduced glutathione (GSH) in the kidney cortex, and by light microscopic examination of kidney sections. The results indicated that concomitant treatment with gum Arabic and GM significantly increased creatinine and urea by about 183 and 239%, respectively (compared to 432 and 346%, respectively, in rats treated with cellulose and GM), and decreased that of cortical GSH by 21% (compared to 27% in the cellulose plus GM group) The GM-induced proximal tubular necrosis appeared to be slightly less severe in rats given GM together with gum Arabic than in those given GM and cellulose. It could be inferred that gum Arabic treatment has induced a modest amelioration of some of the histological and biochemical indices of GM nephrotoxicity. Further work is warranted on the effect of the treatments on renal functional aspects in models of chronic renal failure, and on the mechanism(s) involved.

Acute Kidney Injury↗

Effect of gum arabic in an oral rehydration solution on recovery from diarrhea in rats.

BACKGROUND: It has been shown that gum arabic, a soluble fiber, enhances water, electrolyte, and glucose absorption from oral rehydration solutions in jejunal perfusion of healthy rats and in animals with theophylline-induced secretion or chronic osmotic-secretory diarrhea. This report concerns a study of the effectiveness of an oral rehydration solution supplemented with gum arabic, during recovery from chronic osmotic secretory diarrhea in free-living rats. METHODS: Chronic diarrhea was induced in 60- to 80-g juvenile rats by providing a magnesium citrate-phenolphthalein solution as the sole fluid source for 7 days. This led to diarrhea characterized by dehydration, soft stools, increased cecal volume, decreased food and fluid intake and failure to gain weight. After 7 days of diarrhea, rats recovered for 24 hours with either tap water or an oral rehydration solution (90 mM Na, 111 mM glucose, 20 mM K, 80 mM chloride, 20 mM citrate) with or without 2.5 g/l gum arabic. RESULTS: Although all three solutions improved the diarrhea, optimal recovery from diarrhea was achieved with the gum arabic-supplemented oral rehydration solution. After 4 hours and 24 hours, rats drinking the gum arabic-supplemented solution gained more weight and had lower fecal output than rats receiving water or the rehydration solution without gum arabic. All three solutions normalized plasma osmolality after 24 hours. CONCLUSIONS: The positive effects of the gum arabic-supplemented rehydration solution on fluid and electrolyte absorption seen during jejunal perfusion also occurred during recovery from chronic osmotic secretory diarrhea, when free-living animals drank the solution ad libitum.

Animals↗

A comparison of trends in incidence and mortality rates of breast cancer, incidence to mortality ratio and stage at diagnosis between Arab and Jewish women in Israel, 1979-2002.

In Israel, breast cancer is the most common malignancy in women, but there are large intra-population differences. The aim of this study was to compare the incidence and mortality, incidence to mortality rate ratio and stage at diagnosis of breast cancer between Arab and Jewish women in Israel. Data on all cases of breast cancer, stage at diagnosis and mortality were obtained from the National Cancer Registry and the Central Bureau of Statistics. Trends in age-specific and age-adjusted incidence and mortality rates, rate ratios and stage at diagnosis were examined for Arab and Jewish women during 1979-2002. Five-year survival rates for 1995-1999 were compared by stage. Among Arab women, age-adjusted incidence rates increased by 202.1%, from 14.1 per 100,000 in 1979-1981 to 42.6 in 2000-2002. Among Jewish women, the rates increased by 45.7%, from 71.1 per 100,000 women in 1979-1981 to 103.6 in 2000-2002. Incidence to mortality rate ratio increased for both population groups, but it is still lower among Arab women. In every age group, Arab women were more likely to be diagnosed at a more advanced stage of the disease. The rise in breast cancer incidence and mortality rates and the later stage of diagnosis among Arab women emphasize the urgent need for increasing early detection of breast cancer in the Arab population by improving rates of compliance with screening mammography.

Arabs↗

Sarcoidosis in residents of northern Israel of Arabic and Jewish origin: a comparative study.

BACKGROUND: This study describes the features of sarcoidosis among Arab patients and compares it to Jewish patients residing in northern Israel. METHODS: All new cases of biopsy-confirmed sarcoidosis diagnosed between 1980 and 1996 in northern Israel were divided into two groups according to their ethnic origin: Jewish (n = 72) and Arabic (n = 48). Disease parameters were recorded and compared. RESULTS: Arabs and Jews had similar incidence rates that increased from 0.2/10(5) in 1980 to 2/10(5) per year in 1996. The peak incidence was in the sixth and seventh decades and the female/male ratio was 2 and 1.4 for Arabic and Jewish patients, respectively. Jewish patients had higher proportion stage II-IV pulmonary disease (78% vs. 51.2%) while their Arabic counterparts had higher proportion of stage I disease (70.8% vs. 41.7%). The proportion of extra-thoracic organ involvement was similar. Different disease phenotype indicated differed diagnostic procedures; higher proportion of mediastinoscopy for stage I disease among Arabic patients (47.9% vs. 20.8%, P = 0.015) and trans-bronchial biopsy for stage II-IV pulmonary disease among Jewish patients (25% vs. 8.35%, P = 0.05). Corticosteroids were used in a non-significantly higher proportion of Jewish patients (56.9% vs. 43.8%, P > 0.05). Of six sarcoidosis-related deaths (5%), five occurred in Jewish patients. CONCLUSIONS: This study has documented different forms of presentation, clinical manifestation, severity and prognosis of sarcoidosis present among patients of Arabic and Jewish origin residing in the area of northern Israel.

Adolescent↗

A nursing home in Arab-Israeli society: targeting utilization in a changing social and economic environment.

This article is a case study of the first 10 years of operation (1992-2002) of the Dabouriya Home for the Aged, the first publicly funded culturally adapted nursing home for Israeli citizens of Arab descent. Although 44% of Arab Israelis and 26% of Jewish Israelis aged 65 and older are disabled, in 1999, 4.3% of the Jewish population but only 0.7% of the Arab-Israeli population aged 65 or older lived in long-term care institutions; disabled Arab-Israeli elderly were mainly cared for by families. As Arab-Israeli society modernizes and traditional caregiving is reduced, alternatives must be found for this growing, disabled population. Medical and administrative records of 404 people admitted consecutively to a 136-bed facility over 10 years were analyzed. Two distinct segments of the needy population were served: people with independent activity of daily living (ADL) function but little or no family to provide help with intermediate ADLs and those dependent in ADLs and with health problems, especially dementia. Economic, demographic, and social changes in Arab-Israeli society may mean that traditional caregivers will not be able to adequately care for this highly disabled population. Administrators of the public health system in Israel should be aware of the underutilization of publicly funded long-term care by disabled Arab Israelis and the lack of care alternatives for the population that does use nursing homes, because there may be severe consequences in terms of caregiver burden and social stress when disabled elderly people remain in unsuitable environments.

Activities of Daily Living↗

Ethnic differences in colorectal cancer among Arab and Jewish neighbors in Israel.

OBJECTIVES: Migrant studies indicate that the differences in the incidence of colorectal cancer (CRC) are probably environmental and not genetic. There is epidemiological documentation that Israeli-born Arabs have much less CRC than Israeli-born Jews. We investigated these differences among Jews and Arabs living within the same central coastal region in Israel. METHODS: The files of pathology-diagnosed patients with CRC hospitalized from 1988 to 1996 were reviewed, and demographic data and incidence and location of malignancies were retrieved for this relative frequency study. RESULTS: Of the 527 patients (51.4% men) diagnosed as having CRC, 489 (92.8%) were Jews and 38 (7.2%) were Arabs (p < 0.001), representing 0.46% and 0.04% of the respective populations in the region. The average age at disease diagnosis of the Jews was 73.8 yr and that of the Arabs 61.4 yr (p < 0.001). Both groups shared identical health facilities and habits of attending them. The Arab patients were or had been employed in occupations that involved more physical activity. The site of lesion was on the right colon in 24.9% of all the cases-23.5% of the Jewish patients and 42.1% of the Arab patients (p < 0.001). Rectal cancer was found in 25.7% of the former and 15.8% of the latter (p < 0.001). CONCLUSIONS: The lower incidence of CRC among the Arabs persisted over time, and that group had greater right side and lesser rectal involvement than their Jewish neighbors, possible indications of genicity. The incidence of CRC among the Jews rose concomitantly with "Westernization" of their lifestyle, supporting a role for environmental influences.

Adult↗

Alcohol drinking patterns among Jewish and Arab men and women in Israel.

OBJECTIVE: Jews and Muslim Arabs comprise the bulk of modern Israeli society. Jewish tradition permits controlled alcohol drinking, whereas Muslim tradition prohibits the use of any alcohol. Increasing exposure of the traditionally conservative Arab sector to the Western culture of modern Israel might impact on and be reflected in the drinking patterns of these two populations. The influence of religiosity and other factors on drinking patterns of Jewish and Arab adults are examined using data from a 1995 national household survey. METHOD: Past month drinking is assessed in this nationally representative sample of nearly 5,000 Jews and 1,000 Arabs (N = 5,954, 60% women). Unadjusted and adjusted odds ratios (ORs) are presented to describe associations between any and heavy drinking and nationality group, religiosity, education and marital status among men and women. Modification of the nationality-drinking relationship by religiosity is also examined. RESULTS: Any past-month drinking was reported more often by Jewish respondents than Arab respondents (OR = 2.9, 95% Cl: 2.5-3.4), and this difference remained statistically significant after accounting for the effects of the other covariables. This cross-nationality difference was more pronounced among women (OR = 6.4, 95% Cl: 4.6-8.8) than men (OR = 2.3, 95% CI: 1.8-2.9). The proportion of drinkers who reported heavy drinking in the past month, however, was lower among Jews (OR = 0.3, 95% CI: 0.2-0.4). Significantly higher rates of drinking were noted for secular men and women than for religious respondents in both nationality groups. Rates of drinking were more similar among secular Arabs and Jews than among religious respondents of these nationality groups. CONCLUSIONS: These results add support to the theory that adherence to religious traditions continues to serve as a barrier against drinking among both Arabs and Jews. Further work is required to determine if these patterns are stable over time and whether genetic factors are contributing to the sociocultural influences.

Adolescent↗

Familial Mediterranean fever: clinical and genetic characterization in a mixed pediatric population of Jewish and Arab patients.

OBJECTIVE: Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease which primarily affects non-Ashkenazi Jews, Armenians, Arabs, and Turks. The gene responsible for the disease (MEFV/FMF) has been recently identified. Four common mutations in exon 10 of the MEFV gene seem to account for 86% of the DNA variations identified in patients with FMF. We conducted a phenotype/genotype correlation study in a mixed population of Jewish and Arab children with FMF. STUDY DESIGN: Seventy patients clinically diagnosed as having FMF underwent molecular genetic studies using polymerase chain reaction and restriction endonuclease digestion methods to detect the presence of the four mutations (M694V, M680I, V726A, M694I). We then correlated the presence of each mutation with ethnic origin, age of onset, clinical manifestations, disease severity, and occurrence of amyloidosis. RESULTS: The M694V mutation, which is predominant in non-Ashkenazi Jews, was found in 92% of our Jewish patients and in only 30% of the Arab patients. All four mutations were identified among 94% of the Arab patients, but with no particular prevalence for any one of them. The presence of a homozygous M694V mutation was significantly associated with a more severe form of the disease: the clinical onset of the disease manifested at an earlier age; the number of attacks per month was higher; the global assessment by the treating physician and the severity of pain scored higher; and arthritis was more frequent. Only patients with the M694V mutation had a family history of amyloidosis. No association was found between the type of mutation and the predominance of fever, abdominal pain, pleuritis, skin eruption, or response to colchicine in the clinical picture. CONCLUSIONS: Homozygosity for the M694V mutation, predominant among North African Jews, is associated with a severe course and prognosis for FMF. This mutation is less common among Arabs and, when present, occurs almost only in heterozygous form. In Arab patients, the disease tends to run a milder course and seems to bear a better prognosis. The phenotype/genotype patterns that are evident from our study of a mixed series of Jewish and Arab children with FMF might provide a rational basis for counseling about the natural history of the disease and for clinical treatment of FMF patients and their families.

Adolescent↗

Possible interethnic differences in omeprazole pharmacokinetics : comparison of Jordanian Arabs with other populations.

BACKGROUND AND OBJECTIVE: Considerable ethnic differences have been reported in the incidence of the poor metaboliser (PM) genotype of cytochrome P450 (CYP) 2C19. The frequency of this genotype was found to be much higher in Oriental persons (13-23%) than in American or European populations (3-5%). There are, however, no valid data published for Arabic subjects. The present study was conducted to evaluate pharmacokinetic parameters of omeprazole after a single dose in healthy Jordanian Arabic subjects and to compare the results with data published for other populations. METHODS: Seventy-four healthy male Jordanian Arabic volunteers contributed to the study, which was performed at Al Essra Hospital in Amman, Jordan. After an overnight fast, omeprazole was administered as a single Losec 20mg capsule. A total of 20 blood samples were collected over a 10-hour period after administration. Omeprazole pharmacokinetic parameters were determined from the plasma concentration-time profiles using the WinNonlin software. Kolmogorov-Smirnov's test and probit plots of omeprazole area under the plasma concentration-time curve (AUC) data were used to analyse the frequency distribution of phenotypic data. RESULTS: The mean pharmacokinetic parameters and their corresponding coefficient of variation (CV%) for peak plasma concentration (Cmax), AUC from time zero to infinity (AUCinfinity), time to reach Cmax (tmax), apparent oral clearance (CL/F) and elimination half-life (t(1/2)) were 314.96 ng/mL (56%), 923.2 ng . h/mL (108.6%), 2.1h (44%), 0.66 L/h/kg (92%) and 1.5 h (56.6%), respectively. Interindividual differences in the current study were high for all pharmacokinetic parameters, yet comparable to CVs reported in nonphenotyped subjects identified within other ethnic groups (40.3-159% for AUC and 39-48.2% for Cmax). The frequency distribution of all parameters, particularly the AUC, was shown to be trimodal. This has proposed the presence of three distinct phenotypes, designated as extensive metabolisers (EMs), slow-extensive metabolisers (SEMs), and PMs, with corresponding frequency of 36.5%, 39.2% and 24.3%, respectively. After stratification, the relative mean AUCs of omeprazole in EMs, SEMs and PMs were 1 : 2.7 : 9.3 (all p < 0.001). Accordingly, the CL/F of omeprazole showed a ratio of 9.8 : 3.6 : 1 for three phenotype groups, respectively. For other pharmacokinetic parameters including Cmax, t1/2, AUC normalised for bodyweight (AUCN), Cmax/dose and AUC/dose, there were also significant differences between the three groups. CONCLUSIONS: The current pharmacokinetic study revealed that the majority of the Jordanian Arabics seemed to be more properly classified within the EM phenotype. More specifically, the observed metabolic rates of heterozygous and homozygous Jordanian Arabic EMs were more comparable to those of Caucasian EMs than Oriental EMs. Consequently, higher dosage requirements can be expected among most of the Jordanian Arabics. Yet, the incidence of PMs is significant and they seemed to exhibit a similar pharmacokinetic pattern to Chinese PMs in terms of long-term exposure (clearance and AUC) as well as short-term exposure (Cmax) parameters, after adjustment for dose and bodyweight. Therefore, further clinical application of CYP2C19 polymorphism is anticipated in Jordanian Arabic mixed population, particularly if long-term use of omeprazole is intended.

Adult↗

Deniz: the electronic database for beta-thalassemia mutations in the Arab world.

OBJECTIVE: Data on the distribution of beta-thalassemia mutations in Arab populations are usually destined to disparate locations and much of these become increasingly difficult for an average researcher to locate. That is why we aimed at establishing an electronic database network, called Deniz, for beta-thalassemia allele frequency distributions in the Arab world at http://biobase.fatih.edu.tr. METHODS: The scheme of the database combines the benefits of the relational and hierarchical systems. Detailed statistics of the frequencies of beta-thalassemia mutations are retrieved in tabular forms. Multiple permanent connections allow flexible movement within the database. Queries are processed by the systems language and sent to the user's browser as hypertext markup language documents. RESULTS: The database catalogues the frequencies of beta-thalassemia mutations in 14 Arab countries as pooled from the analysis of 3,138 chromosomes by 36 laboratories. Of the 57 B-globin gene mutations reported in Arabs, IVS-I-110 (G-A), IVS-I-5 (G-C), IVS-I-6 (T-C), IVS-II-1 (G-A), and IVS-I-1 (G-A) are the most encountered and they account for approximately two thirds of the Arab chromosomes registered in Deniz. CONCLUSION: In addition to its importance as a hub of updated information on the distribution of beta-thalassemia mutations in Arabs, information in Deniz may be used to predict diagnostic strategies that may be offered to natives of unstudied countries. Incidence data may also give important clues on the possible origins of beta-thalassemia in the Arab world. The integration of Deniz with other databases is currently in process and researchers are invited to contribute to the growth of the database.

Alleles↗

[Knowledge and attitudes among women in the Arab village regarding contraception and family planning and the reasons for having numerous children].

BACKGROUND: Families with numerous children (5 or more) are a common phenomenon in the Arab sector in Israel. Whereas the fertility rate of Jewish women is 2.6, Muslim women have a rate of 4.6. Research has found that approximately half of the children were the result of unplanned pregnancies. Among the risk factors for unplanned pregnancies are: low income, the woman's level of education and marriage at a young age. In Israel a number of studies have been conducted on the use of contraception, in general, and on the status of women in the Arab population. However, to the best of our knowledge, there has not yet been a study in which Arab women have been asked how they customarily act on the subjects of family planning and contraception and what their attitudes are vis-à-vis having numerous children. OBJECTIVES: The aim of this study was to examine to what extent family planning and use of contraception exist in the Arab population and to determine the reasons for having so many children. The reasons examined included: the couple's wishes, religious faith, knowledge concerning contraception, socio-economic status and education. METHODS: A detailed questionnaire was prepared, which included socio-demographic details and questions of knowledge and attitudes pertaining to family planning and contraception and the reasons for having numerous children. The questionnaire was completed by the clinic staff, who interviewed all the women, ages 20-45, who had 5 or more children. RESULTS: Three hundred and three Arab women were interviewed, out of a total of 391 who had 5 children or more (compliance rate of 77.5%). Sixty percent of these women were married before the age of 18 and most of them are housewives (96.4%). A total of 18.8% of the women had an education of 0-4 years, 66.5% had an education of 5-8 years and 14.8% received 9 or more years of education. Most of them (92%) claimed that the decision regarding the number of children was jointly made with their husband; 24.8% thought that breastfeeding prevents pregnancy, about half of them became pregnant while breastfeeding. As to contraceptives--6.9% are currently taking contraceptive pills; 60.8% use IUD; and 11.2% had tubal ligation, most of them during a Caesarian section. In a single-variable analysis, a significant correlation was found between the women with a low level of education and more than 7 children. As the educational level rises there are fewer children in the family (P < 0.001). A significant correlation was also found between the low education of the husband and a number of children greater than 7 (P < 0.004). It was found that there is a significant high rate of women with 6 or more children that had tubal ligation. In a multi-variable analysis of the logistic regression, it was found that independent variables that predict a number of children higher than 7 are tubal ligation and the woman's level of education. The probability of uneducated women having 7 or more children is 15.2 times greater than for women with high education. Similarly, the probability that women who underwent tubal ligation have 7 or more children is 5.8 times greater than women who used no contraception. CONCLUSIONS: This study reinforces findings from previous studies that indicate the connection between the parents' education, particularly the wife's education, and the number of children. Similarly, in the rural Arab sector in Israel, the woman's education is the most significant variable determining the number of children. Moreover, we have seen that only when the number of children is particularly high and the woman's age is high, she is persuaded to have tubal ligation, as opposed to other means of contraception. These results reinforce the approach, according to which there is great importance to the fact that women in the Arab sector should obtain a high school education and more, so as to be able to properly plan the size of their family.

Adult↗

Differences in infant mortality rates between Jews and Arabs in Israel, 1975-2000.

BACKGROUND: The infant mortality rate is a health status indicator. OBJECTIVES: To analyze the differences in infant mortality rates between Jews and Arabs in Israel between 1975 and 2000. METHODS: Data were used from the Central Bureau of Statistics and the Department of Mother, Child and Adolescent Health in the Ministry of Health. RESULTS: The IMR in 2000 was 8.6 per 1,000 live births in the Israeli Arab population as compared to 4.0 in the Jewish population. Between 1970 and 2000 the IMR decreased by 78% among Moslems, 82% among Druze, and 88% among Christians, as compared to 79% in the Jewish population. In 2000, in the Arab population, 40% of all infant deaths were caused by congenital malformations and 29% by prematurity, compared to 23% and 53%, respectively, in the Jewish population. Between 1970 and 2000 the rate of congenital malformations declined in both the Arab and Jewish populations. In the 1970s the rate was 1.4 times higher in the Arab community than in the Jewish community, and in 2000 it was 3.7 times higher. CONCLUSION: As in the Jewish population, the IMR in the Arab community has decreased over the years, although it is still much higher than that in the Jewish community. Much remains to be done to reduce the incidence of congenital malformations among Arabs, since this is the main cause of the high IMR in this population.

Arabs↗

Differences between Israeli Jews and Arabs in morbidity and mortality rates for diseases potentially associated with dietary risk factors.

BACKGROUND: Cancer, ischemic heart disease, cerebrovascular disease and diabetes together comprise almost 70% of the causes of death in Israel. Dietary factors such as total caloric intake, saturated fats, polyunsaturated fatty acids, trace elements, vitamins, certain proteins, and fiber have all been suggested as playing a role in the pathogenesis of these diseases. AIM: In this study, patterns of mortality and morbidity (where available) for selected diseases were compared between the Jewish and Arab population groups in Israel. METHODS: Data on cause-specific mortality in Israel between 1973 and 1994 were obtained from the Israel Central Bureau of Statistics. Age-adjusted rates for selected diseases were compared between the Jewish and Arab population groups. RESULTS: Until 1987, the age-adjusted ischemic heart disease mortality rates in the Arab population were slightly lower than those in the Jewish population. Since 1990, they have been slightly higher. Cerebrovascular disease mortality rates have consistently been higher in the Arab population and the gap has been increasing. Similarly, the mortality rates for diabetes mellitus were slightly higher in the Arab population during the 1970 and 1980s and the gap has increased markedly. On the other hand, age-adjusted mortality rates from colorectal cancer are about three times as high and breast cancer mortality rates about twice as high in the Jewish population. The differences for incidence rates are even greater. CONCLUSIONS: This study demonstrates the contradictory mortality rates for cardiovascular disease as compared with colon and breast cancer in the Jewish and Arab population. While representative dietary data for the populations are lacking, there is evidence that the dietary patterns of the Jewish and Arab population groups differ in many important aspects. It is possible that this may at least partly explain the contradictory differences in mortality and morbidity. The national nutrition surveys currently being initiated by the Ministry of Health should contribute to a better understanding of this subject.

Arab World↗

From the biomedical model to the Islamic alternative: a brief overview of medical practices in the contemporary Arab world.

Following its climax in the 8th century under the Abbasids of Baghdad, the Arab world entered a prolonged period of division and decadence. "Western" medicine was introduced in the 19th century with the support of the general population. The historical participation of Arabs in the elaboration of that "Western" biomedical model and its apparently consensual re-introduction into the Arab world diffused any sense of cognitive alienation vis-à-vis practices promoted initially by non-Arab doctors. In the late 1960s, Islamist thinkers started proposing "Islamic medicine" as an alternative to the encroachment of the "Western" biomedical model within Arab and Muslim nations. In Islamic medicine, disease is attributed to lack of attention to the spiritual dimension of human beings, yet intermediate causal pathways are not provided. Alongside "orthodox" concepts, Islamic medicine promotes some herbal remedies, in addition to faith-healing through prayer and the recitation of holy verses. While most of those practices may be beneficial, they may cause some harm to patients if they entail delaying or denying timely recourse to "orthodox" medical care. There are currently no Islamic medicine training programs in any Arab country, and Islamic medicine has not emerged as a comprehensive health alternative comparable to other non-Western health models.

Arab World↗

Cancer in the Africans and Arabs of Zanzibar.

Among 392 cancers histologically diagnosed in Zanzibar during 1957-62 and 1964-67, a definite pattern seems to emerge. Skin and cervix cancers were the most common types in both Africans and Arabs. Skin cancer was predominantly of the squamous cell type. The Zanzibar Arabsthus appear to be protected against basal cell carcinoma which in the Arab desert community has been diagnosed with about the same frequency as squamous-cell carcinoma. In the same manner, the Zanzibar Arab immigrants seem to have a reduced risk for stomach and oesophageal cancers, which are common in other Arab countries. This is probably because Arabs in Zanzibar have adopted the dietary habits and other customs of the Zanzibar Africans in whom cancer of the alimentary tract seems to be uncommon. On the other hand, unlike Zanzibar Africans, the Arabs have an increased risk for Hodgkin's disease similar to that of the Middle East Arab population.

Africa, Eastern↗

Lung cancer in Israel, 1962-1982. I. Jews and Arabs.

The magnitude and dynamics of lung cancer incidence in Jews and Arabs in Israel between the years 1962 and 1982 were studied. In general, age-standardized incidence rates increased consistently between the years 1962 and 1976 among Jewish (24% increase) and Arab (39%) males, and to a lesser degree among Jewish females (15%). Arab females had the highest (77%) increase. From 1977 to 1982 a general decrease in incidence rates, which was largest among Arab males (19%) and females (15%), was noted. Rates among Jewish males are currently 26% higher than among Arab males, and are 162% higher among Jewish females than in Arab females. Lung cancer rates in both males and females in Israel (Jews and Arabs) are lower than in most developed countries in the world. Among the possible reasons are differences in the population risk factors profile, availability of health care and the level of diagnosis and ascertainment of cases.

Adolescent↗

Are Arabic numerals processed as pictures in a Stroop interference task?

In a picture-word interference task, picture naming is interfered by an incongruent word, but word naming is hardly hindered by the presence of an incongruent picture. In this study, we investigated whether Arabic digits are processed more like pictures or like words. We report two experiments in which Arabic digits and verbal numerals were confronted in a Stroop task. Arabic digit naming is interfered by the presence of an incongruent verbal numeral, while naming the verbal numeral is not influenced by the presence of an incongruent Arabic digit. In a second experiment, we excluded the hypothesis that the results are due to ignoring the Arabic digits: interferences from an incongruent distracter were similar for both notations in a semantic classification task. It seems that an asemantic conversion for Arabic digits is too slow to influence naming times, and that Arabic digit naming, like picture naming, is semantically mediated.

Adolescent↗

Assessing Arab-American health care needs.

A health needs assessment was conducted with Arab-American immigrants in northern California. Data were obtained from community forums, key informants, the U.S. Census, and from a survey of 47 Arab immigrants. In the community forums, parenting difficulties, marital conflicts, and health risks were identified. Key informants (clergy, community leaders, health professionals) identified mental health problems related to child rearing, referrals for appropriate services, education to assist Arab women interface with the health and education systems, and translation and cultural interpretation for Arab patients and health care providers. Arab patients requesting health care identified referrals for appropriate care, advocacy, education about the medical regimen, and technical assistance obtaining care. Social indicators indicated potential needs for health services for those of lower income. A survey of 47 Arab-Americans indicated that predominant illnesses experienced in the past year were upper respiratory infections, cardiovascular and hypertension, diabetes, and family and social stress. Health-related problems reported most frequently were family stress, adjusting to the U.S., managing acute illness, coping with adolescents, and marital stress. For the most part, this group was satisfied with medical care received and stated that their most important health services were health education, availability of Arab speaking health providers, and referrals for appropriate treatment.

Attitude to Health↗