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At least 109 records · Page 6Linked to original sources

[A case of ASD with SLE treated with Carmeda BioActive surface circuit in cardiopulmonary bypass system].

A 61-year-old woman of ASD complicated with SLE was operated on. We used a heparin coating Carmeda BioActive Surface (CBS) in cardiopulmonary bypass circuit for the purpose to prevent the postoperative complications due to the reduced complement activation by SLE. This system could prevent the decline of the reduced complement activation during cardiopulmonary bypass and after operation. The management of steroid therapy for SLE patient, usefulness of heparin coating CBS system for hypocomplement disease were discussed.

Anti-Inflammatory Agents↗

Compassionate use of the amplatzer ASD closure device for residual postinfarction ventricular septal rupture following surgical repair.

We report successful transcatheter closure of a post-MI ventricular septal rupture acutely following unsuccessful surgical repair. Catheter closure was accomplished by the use of a 26-mm Amplatzer atrial septal occluder. Initial attempts to close the defect with the use of 28-mm and 33-mm CARDIOSEAL were unsuccessful. Closure technique, immediate and long-term follow-up outcomes are reported.

Aged↗

Delivery sheath tear after modification for ASD closure.

During transcatheter closure of an atrial septal defect with insufficient aortic rim, a standard delivery sheath was modified by cutting a bevel at the distal tip to improve device orientation. The sheath split longitudinally when attempting to recapture the closure device. Troubleshooting allowed a device to be implanted successfully. Pitfalls regarding our sheath modification and methods to overcome prolapse of the left atrial disk into the right atrium are discussed.

Cardiac Catheterization↗

Diagnosis and surgical treatment of five cases of triple shunt (ASD + VSD + PDA).

Five patients with triple shunt (atrial septal defect, ventricular septal defect, and patent ductus arteriosus) were treated surgically during the past twelve years (1978-1989). They developed severe cardiac and respiratory failure in the neonatal period and/or in early infancy. Simultaneous repair of the triple shunt was performed, but initially two patients suffering severe cardiac failure were lost immediately after operation. The following three patients were operated on relatively soon after establishing a definitive diagnosis and a successful outcome was able to be achieved. Repeated evaluation of the patient with echocardiography was necessary for diagnosis. Early primary operation is, therefore, considered to be the treatment of choice after confirming the diagnosis.

Cardiac Catheterization↗

The superior QRS axis in ostium primum ASD: a proposed mechanism.

The influence of abnormal hemodynamics, ventricular hypertrophy, and right bundle branch block on the AQRS was studied pre- and post-operatively in 29 patients with OPSD. The AQRS markedly diminishes with the surgical correction of abnormal hemodynamics and the subsequent resolution of RVH or BVH. With the persistence of ventricular hypertrophy postoperatively or the surgical induction of RBBB, the AQRS either remains unchanged or, in the latter instance, becomes more superior and rightward. The dependence of the superior AQRS on these factors suggests that a left anterior hemiblock is not responsible for this AQRS. In OPSD early activation of the posterobasal region of the left ventricle through an abnormally short posterior fascicle results in a minimal superior AQRS which is then exaggerated in the presence of abnormal hemodynamics, ventricular hypertrophy, or RBBB. Thus, the superior AQRS in OPSD with associated RBBB does not represent a true bifascicular block and has a different natural history and clinical significance.

Adolescent↗

A possible association between fetal/neonatal exposure to radiofrequency electromagnetic radiation and the increased incidence of autism spectrum disorders (ASD).

Recently disclosed epidemiological data indicate a dramatic increase in the incidence of autism spectrum disorders. Previously, the incidence of autism has been reported as 4-5 per 10000 children. The most recent evidence indicates an increased incidence of about 1 per 500 children. However, the etiology of autism is yet to be determined. The recently disclosed data suggest a possible correlation between autism incidence and a previously unconsidered environmental toxin. It is generally accepted in the scientific community that radiofrequency (RF) radiation is a biologically active substance. It is also readily acknowledged that human exposures to RF radiation have become pervasive during the past 20 years, whereas such exposures were uncommon prior to that time. It is suggested that fetal or neo-natal exposures to RF radiation may be associated with an increased incidence of autism.

Autistic Disorder↗

Use of a donor heart that had undergone previous cardiac surgery for ASD closure.

We report the use of a heart from a 19-year-old female donor who had undergone open heart surgery for closure of an atrial septal defect at the age of 12. The explantation procedure was modified to prevent hemodynamic instability. The recipient, a 59-year-old male with increased pulmonary vascular resistance had an uneventful recovery after transplantation.

Adult↗