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Computerizing reading training: evaluation of a latent semantic analysis space for science text.

The effectiveness of a domain-specific latent semantic analysis (LSA) in assessing reading strategies was examined. Students were given self-explanation reading training (SERT) and asked to think aloud after each sentence in a science text. Novice and expert human raters and two LSA spaces (general reading, science) rated the similarity of each think-aloud protocol to benchmarks representing three different reading strategies (minimal, local, and global). The science LSA space correlated highly with human judgments, and more highly than did the general reading space. Also, cosines from the science LSA spaces can distinguish between different levels of semantic similarity, but may have trouble in distinguishing local processing protocols. Thus, a domain-specific LSA space is advantageous regardless of the size of the space. The results are discussed in the context of applying the science LSA to a computer-based version of SERT that gives online feedback based on LSA cosines.

Artificial Intelligence↗

Building the TeraGrid.

On 1 October 2004, the most ambitious high-performance Grid project in the United States-the TeraGrid-became fully operational. Resources at nine sites--the San Diego Supercomputer Center, the California Institute of Technology, the National Center for Supercomputing Applications, the University of Chicago/Argonne National Laboratory, Pittsburgh Supercomputing Center, Texas Advanced Computing Center, Purdue University, Indiana University and Oak Ridge National Laboratory-were joined via an ultra-fast optical network, unified policies and security procedures and a sophisticated distributed computing software environment. Funded by the National Science Foundation, the TeraGrid enables scientists and engineers to combine distributed, multiple data sources with computation at any of the sites or link massively parallel computer simulations to extreme-resolution visualizations at remote sites. A single shared utility lets multiple resources be easily leveraged and provides improved access to advanced computational capabilities. One of the demonstrations of this new model for using distributed resources, Teragyroid, linked the infrastructure of the TeraGrid with computing resources in the United Kingdom via a transatlantic data fibre link. Once connected, the software framework of the RealityGrid project was used to successfully explore lattice-Boltzmann simulations involving lattices of over one billion sites.

Computer Security↗

Bioinformatics in neurosurgery.

WITH THE COMPLETION of the Human Genome Project, the amount of molecular biological sequence data available in public databases has reached staggering proportions. Data continue to accumulate at an exponential rate in the postgenomic era. Compilation, storage, searching, sharing, studying, and transmitting of all these data present formidable challenges. To keep pace with this extant database, the science of bioinformatics (sometimes called computational biology) has evolved. Bioinformatics is the combination of biology and computers and usually involves the storage or analysis of molecular biological sequence data at either the deoxyribonucleic acid, ribonucleic acid, or protein (amino acid) level. Most bioinformatics tools are freely available on the Internet for use by investigators around the globe. The collective wisdom from bioinformatics databases worldwide will continue to spawn advances in the neurological sciences for generations to come. Neurosurgeons must be aware of the power and potential applications of bioinformatics for the analysis of neurosurgical diseases.

Animals↗

Biostatisticians, biostatistical science and the future.

Biostatistical Science is in a 'golden period'. The definition of Biostatistical Science is the application of statistics, probability, mathematics and computing to advance our understanding of the subject matter in the biomedical sciences. Our field is experiencing unparallel developments due of the advances in communication and computing. We are becoming more global, we have resources which can expand educational opportunities for distant learning; the growth of quantitative methods in the biomedical sciences has made biostatistical science a key component in many research areas. What about the future? Are we receptive to change as many new scientific areas expand? Will the interaction between academia and industry likely to grow-especially in the training of future practitioners of biostatistical science. This paper discusses some of challenges facing our profession if we are to continue to be relevant in the biomedical sciences.

Biological Science Disciplines↗

Increasing the effectiveness and efficiency of academic advising through computerization.

Academic advising is an essential part of any university degree program and becomes especially important in programs where there is competitive and limited admission to professional courses. This requires that academic advisors have ready access to student scholastic and demographic data for counseling and statistical purposes. The use of computers in creating a database for student records has become routine in most universities and colleges. Computerization of these records through the registration process creates a university database with the potential for many different applications. This article describes the development of a computer software program for a baccalaureate science of nursing program that makes use of a university's database to provide the foundation of a computer software program used in the nursing academic advising office. Identifying the special needs and requirements of the nursing advising program and developing a close working relationship with the computer programmer were essential in the development and implementation process. The result was an increase in the effectiveness and efficiency of the advising process, better record keeping, and better use of available student data for statistical purposes.

Databases, Factual↗

A critique of research on the use of activities with persons with Alzheimer's disease: a systematic literature review.

TOPIC: The topic of this paper concerns the use of therapeutic activities with persons with Alzheimer's disease (AD). PURPOSE: The purpose is to present a critique of the research on these activities, with an emphasis on methodology. ORGANIZING CONSTRUCT AND SCOPE: Nursing literature identifies a number of purposes for activities for persons with AD. Activities should be therapeutic, enhance quality of life, arrest mental decline, and generate and maintain self-esteem. Other purposes of activities for this population are to create immediate pleasure, re-establish dignity, provide meaningful tasks, restore roles, and enable friendships. Activities may be more important to the psychological state of well-being of persons with dementia than the general physical and social environments in which they live. SOURCES: The literature reviewed was identified with the use of computer data bases (Medline - 1991-March 2001; Cumulative Index of Nursing and Allied Health Literature (CINAHL) - 1991-March 2001; and PsychLit - 1988-March 1999). In addition, data bases of Science Citation Index and Social Science Citation Indexes as they appear in the computer base, Web of Science, were searched for 1992-2001. The time period for each search was determined by the manner in which the literature was grouped for inclusion in the particular database. Hand searches of 11 selected journals included the years 1993-2001. The search dates were selected to reflect the time period when the largest number of studies on activities and AD have appeared in the professional literature. We critique a total of 33 studies. CONCLUSIONS: While researchers have demonstrated interest in the use of activities with persons with AD, theoretical and methodological difficulties, unclear findings and gaps exist, including a lack of emphasis on gender, ethnic, racial or cultural differences. Sampling issues involving diagnosis and staging complicate the research on individuals with AD. Case studies, single subject experimental designs, and tightly controlled quasi-experimental and experimental designs are needed to advance knowledge in this important area.

Alzheimer Disease↗

Position of information science in the medical and health studies curricula.

Innovation of both the content and forms of informatics teaching directed on exploitation of technical facilities and methods of information and communication technologies (ICT) in non-informatics universities study programmes and in life-long education is still actual today. Expanding knowledge base of the life and health sciences requires to form new skills to educate the end-users and facilitate an immediate information access. Theoretical and practical teaching in pregradual medical and health studies includes the basic contacts of students with the modern technique and special medical devices supported or completed by computers. The teaching of information science and corresponding subjects represents small but important part of medical and health studies curricula at all medical faculties in Slovakia (Fig. 2, Ref. 8).

Curriculum↗

Development of a computer-adaptive test for depression (D-CAT).

Depression is one of the most prevalent mental health problems and measuring depressive symptoms becomes increasingly important in science as well as medical practice. Computer Adaptive Tests (CAT) based on the Item Response Theory (IRT) promise to enhance measurement precision and reduce respondent's burden. Our aim was to develop a CAT application to measure depressive symptoms. Three thousand two hundred seventy psychosomatic patients answered an overall of 11 mental health questionnaires at the University Clinic in Berlin. Three independent reviewers rated 144 items out of these questionnaires as indicative of depressive symptoms. All items underwent six empirical steps to analyze unidimensionality, local independence and item discrimination. Finally 64 items could be used to calculate item parameters applying a Generalized Partial Credit Model (GPCM). CAT scores were estimated using an 'expected a posteriori' algorithm (EAP). Two simulation experiments showed that for theta values within the range of 2SD around the mean (98% of the cases), the latent trait can be estimated out of approximately six items with a predefined standard error of [Symbol: see text] 0.32 (reliability rho [Symbol: see text] 0.90). The CAT-scores correlated high with scores of all depression items (r = 0.95), with the Beck Depression Inventory (r = 0.79) and with a CES-D 8 item short form (r = 0.76). We conclude that the Depression-CAT measures depressive symptoms with high precision and low respondent burden.

Adolescent↗

Applications of computer modelling for the design of orthopaedic, dental and cardiovascular biomaterials.

Biomaterials do not escape from the general trend present in all contemporary science and technology towards increasing use of computers and information technology. In this paper the use of computer modelling for the design of biomaterials is discussed. The word 'biomaterials' is interpreted in its broadest sense, i.e. referring to any foreign object brought into the body for temporary or permanent use. Computer modelling will first be discussed as a tool to model biological structures (bones, arteries) or to investigate and simulate biological interactions at implant-host interfaces. It will then be illustrated how computer modelling, using insights gained from the modelling of the biological structures themselves, is used in the design process of dental, orthopaedic and cardiovascular prostheses. The area of computer modelling for biomaterials applications has become so vast that an exhaustive overview is impossible in the framework of one paper. Rather, some illustrative case studies will be discussed which are, in the opinion of the authors, representative of general trends in this challenging domain of science on the boundary between engineering and medicine.

Cardiovascular Diseases↗

The Statistical Package for the Social Sciences (SPSS) as an adjunct to pharmacokinetic analysis.

Computer techniques for numerical analysis are well known to pharmacokineticists. Powerful techniques for data file management have been developed by social scientists but have, in general, been ignored by pharmacokineticists because of their apparent lack of ability to interface with pharmacokinetic programs. Extensive use has been made of the Statistical Package for the Social Sciences (SPSS) for its data handling capabilities, but at the same time, techniques have been developed within SPSS to interface with pharmacokinetic programs of the users' choice and to carry out a variety of user-defined pharmacokinetic tasks within SPSS commands, apart from the expected variety of statistical tasks. Because it is based on a ubiquitous package, this methodology has all of the benefits of excellent documentation, interchangeability between different types and sizes of machines and true portability of techniques and data files. An example is given of the total management of a pharmacokinetic study previously reported in the literature by the authors.

Computers↗

Processing for science.

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Acquired Immunodeficiency Syndrome↗

InfoFair: an annual computer and information event.

Since 1983, the Spencer S. Eccles Health Sciences Library has presented InfoFair, an annual event featuring presentations, exhibits, demonstrations, and workshops on computer and information topics of interest to health professionals and health information providers at the University of Utah Health Sciences Center and throughout Utah. The first InfoFair was held in response to an increasing number of inquiries from library users on how to search MEDLINE from their home or office computers. The focus of InfoFair has expanded and changed over the past nineteen years to reflect changes in library users' computer and information needs, concerns, and interests. While themes and programs have changed, a definite set of trends, guidelines, and procedures have developed based on the experience gained each year. The purpose of this paper is to review and evaluate the changes in InfoFair from 1983 to 2001 and to present information for use by other libraries for planning and presenting similar events.

Computer User Training↗