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At least 1,063 records · Page 59Linked to original sources
PubMed1990

Application of propolis to dental sockets and skin wounds.

The purpose of this study was to examine histologically the effects of propolis topical application to dental sockets and skin wounds. After topical application of either a 10% hydro-alcoholic solution of propolis or 10% hydro-alcoholic solution alone, cutaneous wound healing and the socket wound after tooth extraction were examined. The rats were sacrificed at 3, 6, 9, 15 and 21 days after the operation. The specimens were subjected to routine laboratory studies after staining with hematoxylin and eosin. It was concluded that topical application of propolis hydro-alcoholic solution accelerated epithelial repair after tooth extraction but had no effect on socket wound healing.

Animals↗
PubMed1991

Removal of epulis by CO 2 laser.

From analysis of the epulis patient population for 40 years, it could be established that of 1019 lesions, 12.8% relapsed, in 40% of surgical interventions, with the extraction of the tooth involved. For the removal of epulis, we have developed our own method. As a first step, the tumor is excised by CO 2 laser. Thereafter, excochleation and bone decortication are performed, followed, as a third step, by evaporation. In each case, an attempt is made at preserving the teeth. When necessary, radicular treatment and fixation are performed. Postoperatively, minimal edema and pain occurred, and the majority of the patients were able to work on the first postoperative day. Following laser removal of 63 epulides, recurrence was seen in 5 cases (7.9%) without intraoperative tooth extraction. The combined method was applied successfully also in a hemophilic patient. Besides the conventional laser surgical handpiece, an endoscope of own construction was used on surfaces untreatable by direct sight.

Adolescent↗
PubMed1990

[Removal of epulis using CO2 laser (clinicopathologic analysis and surgical experience)].

From analyzing the epulis patient population of 40 years it could be established that from the 1019 lesions 12.8% relapsed, in 40% of surgical interventions, beside the extraction of the tooth involved. For the removal of epulis an own method has been elaborated by the authors. As a first step the tumour is excised by carbon dioxide laser, thereafter excochleation and bone decortication are performed, which is followed, as a third step, by evaporation. In each case attempt is made at preserving the teeth, when necessary radicular treatment and fixation are done. Postoperatively minimal edema and pain occurred, the majority of the patients was able to work on the first postoperative day. Following laser removal of 63 epulis recurrence was seen in 5 cases (7.9%), without intraoperative tooth extraction. The combined method was successfully applied also in a hemophilic patient. Beside the conventional laser surgical handpiece an endoscope of own construction was also used on surfaces untreatable from direct sight.

Carbon Dioxide↗
PubMed1997

Chronology of alveolar healing following immediate implantation of Ricinus communis polyurethane resin: histometric analysis in rats.

The purpose of the present study was to determine whether granules of Ricinus communis polyurethane resin implanted immediately after tooth extraction interfere with the time course of alveolar wound healing in rats. Progressive bone neoformation in parallel to a decrease in the volume fraction of connective tissue was quantified by a histometric method 1, 2, 3, and 6 weeks after tooth extraction. In spite of the biocompatible nature, the presence of polyurethane resin granules in the cervical third led to a small (9-22%) but significant delay in bone formation in the middle and apical alveolar thirds from the second week on, as compared to controls.

Alveolar Process↗
PubMedDate not supplied

Deterioration of Kearns-Sayre syndrome following articaine administration for local anesthesia.

Worsening of the neuromuscular manifestations in Kearns-Sayre syndrome after administering local anesthesia with articaine has not been reported. The authors describe a severe adverse reaction to local anesthesia with articaine for tooth extraction in a 28-year-old woman with Kearns-Sayre syndrome due to a 5.9-kb mitochondrial DNA deletion. The patient was subjected to local anesthesia with 1.5 mL (60 mg) articaine in the left submandibular nerve for tooth extraction. Five minutes after the injection the patient developed weakness of the limb muscles, extreme fatigue with increased desire to sleep, a feeling of heat, inappetence, and frequent urination. The adverse reaction resolved spontaneously within 48 hours without sequelae. Administration of articaine may cause severe side effects in patients with Kearns-Sayre syndrome. Articaine should be used with caution in these patients.

Anesthesia, Local↗
PubMedDate not supplied

Dental management prior to hematopoietic stem cell transplantation.

The authors investigated oral health treatment in patients scheduled for hematopoietic stem cell transplantation. Fifteen patients were scheduled for bone marrow transplantation: 12 had leukemia, two had aplastic anemia, and one had myelodysplastic syndrome. Twenty-three patients were scheduled to undergo peripheral blood stem cell transplantation: 20 had malignant lymphoma and three had leukemia. Patients with platelet counts of < or = 50,000/mm3 who required tooth extraction and those with platelet counts of < or = 30,000 /mm3 who required scaling received platelet transfusions before the dental treatment. We saw no bleeding problems in these patients. Dental care for patients who had neutrophil counts of > or = 500/mm3 included tooth extractions or scaling, with no postoperative infection. Even those with severe immunosuppression (neutrophil count: 100-150/mm3) tolerated treatment when prophylactic measures, such as intravenous administration of antibiotics, were used. One patient with a neutrophil count of < or = 50/mm3 developed an infection after even conservative therapy. Thus, caution should be exercised when treating patients scheduled for HSCT as even conservative therapy can initiate and infection.

Adult↗
PubMed1986

Blood pressure and electrocardiographic response to dental treatment with use of local anesthesia.

The incidence of ST segment depression during tooth extraction was significantly higher in patients with cardiac disease than it was in patients without cardiac disease, indicating that the cardiac patients experienced myocardial ischemia. The almost equivalent incidence of ST segment depression during anesthetic administration and surgery suggests that the administration of local anesthetic is as stressful as tooth extraction for cardiac patients. Medical consultation before dental treatment and use of stress-reduction techniques may be indicated for patients with or suspected to have cardiac disease.

Adult↗
PubMed2003

Bucco-lingual bone remodeling around implants placed into immediate extraction sockets: a case series.

BACKGROUND: Implants placed immediately after tooth extraction have shown high percentages of clinical success. Few studies in the scientific literature have observed the horizontal bone remodeling in the buccal-lingual direction after immediate placement of implants. The aim of this study was to analyze bone healing and coronal bone remodeling around 15 implants placed immediately after tooth removal without the use of guided bone regeneration (GBR) techniques. METHODS: Ten patients received a total of 15 implants placed immediately after removal of 15 single-rooted teeth. All implants were placed within the alveolar confines, limiting, in most cases, small peri-implant bone defects. After implant placement, the distance from the buccal to lingual bone plate was measured. No membranes or filling materials were used. Primary flap closure was performed in all cases. RESULTS: At second-stage surgery, all peri-implant defects were completely filled and the distance from buccal to lingual bone was measured again. The pattern of bone healing around the neck of immediate implants showed an absence of peri-implant defects and a narrowing of bone crest width in a buccal-lingual direction. The mean distance between buccal bone and lingual bone at the time of implant placement was 10.5 mm (+/- 1.52) and, at second-stage surgery, 6.8 mm (+/- 1.33). CONCLUSIONS: The coronal bone remodeling around immediate implants showed a healing pattern with new bone apposition around the neck of the implants and, at the same time, bone resorption with horizontal width reduction of the bone ridge. The small peri-implant bone defects were completely healed without the use of GBR procedures. An absence of complications during the healing period was also observed, probably due to the absence of barrier membranes and grafting materials.

Adolescent↗
PubMed1996

Immediate implantation of glass-ionomer cement granules increases osteogenesis during rat alveolar wound healing.

A study was conducted to determine whether granules of type III glass-ionomer cement (currently used as a fast-setting lining material and fissure sealant) implanted immediately after tooth extraction interfere with the time course of alveolar wound healing. Histologic examination of the entire socket showed normal progression of the healing process. Progressive bone neoformation in parallel with a decrease in the volume fraction of connective tissue was quantified by a histometric method up to 6 weeks after tooth extraction. The presence of glass-ionomer granules in the cervical third led to a small delay in bone formation by the first week but not thereafter, as also observed in the remaining regions of the alveolus (middle and apical thirds) which tended, in contrast, to show a larger amount of trabecular bone from the third week onwards. These results show that the material does not hinder the wound healing process, and in fact favors bone neoformation.

Alveolar Process↗
PubMed2006

Compliance as a prognostic indicator: retrospective study of 505 patients treated and maintained for 15 years.

BACKGROUND: The relationship of patient compliance to overall tooth prognosis remains controversial. There are little data, often conflicting, that pertain to tooth loss as a function of patient compliance. METHODS: This retrospective study evaluates the impact of compliance (complete versus erratic) on common periodontal clinical variables, such as probing depth, bleeding index, plaque index, and tooth loss for 505 patients in a long-term period of observation (15 to 23 years) and maintenance therapy (at least 10 years). Compliance was defined in two ways for all analyses. Under the definition for compliance 1, patients who missed <30% of all prescribed maintenance visits were classified as complete compliers. Under the definition for compliance 2, patients who never went 2 years without a maintenance visit were classified as complete compliers. Change in clinical variables was dichotomized into reduction in plaque index versus no reduction, reduction in bleeding on probing versus no reduction, reduction in the percentage of periodontal pockets>3 mm versus no reduction, no increase in decayed, missing, or filled teeth (DMFT) versus increase, and no tooth loss versus tooth loss. The effects of both definitions of compliance were then evaluated in a series of multiple logistic regression models with adjustment for potential confounders. RESULTS: The analysis of the dichotomous change in clinical parameters over time revealed that complete compliers tended to show reduction in bleeding on probing and reduction in plaque index compared to erratic compliers for both definitions of compliance. In contrast, complete compliers under compliance 2 were less likely to have a reduction in the percentage of periodontal pockets >3 mm compared to erratic compliers, whereas complete compliers under compliance 1 had about the same likelihood of demonstrating a reduction in periodontal pockets compared to erratic compliers under this classification scheme. Under both definitions for compliance, complete compliers were more likely to exhibit tooth loss than erratic compliers, with the greatest tooth loss exhibited by complete compliers under the definition for compliance 1. CONCLUSIONS: Based on these results, complete compliers under both definitions tended to show a reduction in plaque and bleeding on probing over time. However, change in periodontal pockets and DMFT over time varied according to the definition of compliance that was used. In addition, the results seem to indicate that the decision for tooth extraction made by dental health professionals at maintenance visits may result in greater tooth loss.

Adult↗
PubMed1991

The effect of a teflon membrane to augment the healing of extraction sockets in monkeys.

The present study was undertaken in 9 monkeys to test the effect of a teflon membrane to augment the healing of extraction sockets. The 4 lateral incisors of each animal were extracted using a surgical flap approach. Two of the sockets on one side were covered with teflon membrane (experimental sites), while the same procedure was repeated with the exception of the applications of the teflon membrane on the remaining two sockets of the contralateral side (controls). The distal surfaces of the central incisors were notched at the level of the crest of the alveolar bone as the reference points for measurements of alveolar bone response. Re-entries were performed on three monkeys at 50, 90 and 150 days after tooth extraction and the bone fill of the sockets was evaluated. It was concluded from the results that there was a tendency for the teflon membrane placement to result in a greater amount of clinical alveolar bone fill and lesser extent of bone resorption after tooth extraction.

Animals↗
PubMed1980

Properties of dissociatively extracted fetal tooth matrix proteins. II. Separation and purification of fetal bovine dentin phosphoprotein.

After an initial 4 M guanidine HCl extraction to remove enamel contaminants, subsequent guanidine HCl/EDTA extraction of fetal bovine molar dentin removes almost all of the high molecular weight phosphoprotein from the tissue in a single step. The fetal bovine dentin phosphoprotein is then purified by a series of ion exchange (DEAE-cellulose or DEAE-Se-phacel) and gel filtration (Sepharose CL-6B) chromatographic steps, all under denaturing elution conditions in 7 M urea (ion exchange) or 4 M guanidine HCl (gel filtration). The final purified phosphoprotein product was chromatographically and electrophoretically homogenous. The apparent molecular weight for this fetal bovine dentin phosphoprotein was approximately 100,000 both by 4 M guanidine HCl gel filtration and polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. This value is considerably higher than those previously reported for any other dentin phosphoprotein preparation. Roughly half of the total serine residues in the protein were phosphorylated and these residues together with aspartic acid comprised approximately 80% of the total polypeptide backbone. The purified fetal bovine dentin phosphoprotein was also glycosylated, containing approximately 6 galactosamine, 2 to 3 glucosamine, and 2 to 3 sialic acid residues/mol.

Amino Acids↗