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[Nephrectomy of a giant hypernephroma (5,150 g)].

We report a giant renal adenocarcinoma (5150 g weight) excised in a 52 years old male. He presented a severe clinical symptoms: serious haematuria, fever (40 degrees C), left flank pain, abdominal discomfort and weight loss (10 kg). The patient underwent left renal artery embolization because of severe anemia (blood transfusion: 4 uu) but haematuria didn't decrease; that's why radical surgery was advised. Until our knowledge this case is the largest removed kidney adenocarcinoma published in the world literature (Medline 1966-2001).

Abdominal Pain↗

[Neurogenic gastric tumours. Schwannomas and neurofibromas (author's transl)].

The literature concerning the definition, frequency, development and morphology of neurogenic gastric tumours is reviewed. The clinical, radiological and histological findings in eleven cases seen by the authors are described. The radiological differential diagnosis and errors in diagnosis are discussed. The significance of tumour perforation in making a type diagnosis is pointed out. There are few angiographic reports available at present.

Adult↗

[Esophageal perforations after vagotomy].

Oesophageal perforation after vagotomy is a quite rare complication. We know figures between 0.4 and 0.8%. The radiodiagnostic verification has central significance for a possibly necessary reoperation, and hence the prognosis of the patient, if this perforation is not recognized under the operation, or necrosis of the wall should happen in the early post-operative phase. We give information about four own observations.

Adult↗

Major hepatic resection using vascular isolation and hypothermic perfusion.

The technique and results of 29 major hepatic resections using the method of complete vascular isolation and hypothermic perfusion of the liver are reported. The method enables the surgeon to perform otherwise difficult or impossible resections through chilled bloodless hepatic parenchyma. Major intrahepatic vascular structures can thus be recognized and controlled readily under clear vision. Direct neoplastic involvement of, or tumor thrombi in the portal vein, hepatic vein or vena cava, can be successfully dealt with by appropriate surgical measures. The operative mortality was 10.3% for this series which included many tumors previously deemed unresectable. The technical detail and intraoperative physiologic monitoring crucial to success in the use of the method are described. It is hoped that with the widened scope of resectability afforded by this technique, and the use of adjuvant chemotherapy, the currently experienced low cure rates for hepatic cancer can be improved.

Cyclophosphamide↗

Fungal septicemia in surgical patients.

Opportunistic systemic fungal infections are more frequent than generally realized. Increased awareness and a high index of suspicion of fungal super-infection in the presence of sepsis is required to bring about recognition and therapy. The intravenous catheter is an important portal of entry or may act as a foreign body favoring localization of a septic process. In its presence, fungemia must be guarded against. Whenever an intravenous catheter is removed, its tip should be cultured. Removal alone may be a critical item in therapy. In febrile patients, in whom the course of fever is not established, frequent blood cultures with attention directed specifically at fungi should be obtained. Fungi are not easily isolated and identified and only by requesting special attention from the microbiologist can the diagnosis be established in the average institutional laboratory in time to permit appropriate therapy. Since available therapeutic measures are strikingly effective when instituted early, awareness and alertness on the part of the clinician constitute the key to cure.

Adult↗

Air embolism occurring as a complication of central venous catheterization.

Two patients with air embolism (one fatal) which occurred during intravenous feeding with a central venous catheter are reported. The connection between intravenous administration sets and such catheters is shown to be a danger area which requires further technological improvement. The world literature concerning this hazard is reviewed.

Catheterization↗

Evaluation and complications of 107 staging laparotomies for Hodgkin's disease.

From 1971--1975, 107 staging laparotomies for Hodgkin's disease were performed at the University of Wisconsin Hospitals. Forty-one per cent of patients with abnormal abdominal lymphangiograms preoperatively had abdominal nodes which were negative for Hodgkin's. Thirteen per cent of patients with negative preoperative lymphangiograms had positive nodes at staging laparotomy. Twenty-nine per cent were upstaged by laparotomy, i.e. assigned to a less favorable stage (II A to III A), and 11.2% were downstaged. There were no surgical mortalities. Minor surgical complications occurred in 14.9%, and major ones in 3.7%. We conclude that surgical staging for Hodgkin's disease is valuable in making an accurate diagnosis and, hence, in determining the most effective treatment.

Adolescent↗

Intraperitoneal septic complications after hepatectomy.

One hundred forty-nine elective hepatic resections were performed during the 12 years from 1973 to 1984. Nineteen of these patients (12.8%) developed intraperitoneal septic complications after hepatectomy (IPSCH), of whom 13 died of liver failure. Perioperative variables associated with IPSCH were as follows: (1) right or extended right lobectomy, (2) age greater than 65, (3) operation time greater than 5 h, (4) blood loss at operation greater than 3000 g, and (5) post-operative bleeding, which required laparotomy for hemostasis. Improved outcome of IPSCH since 1981 coincided with the emergence of opportunistic pathogens. Survivors of IPSCH had been diagnosed earlier, all by culture of the subphrenic drainage, and all had a lower bilirubin level at the time of diagnosis. It is concluded that secure hemostasis and avoidance of tissue devitalization during hepatectomy are essential to reduce the incidence of IPSCH and that routine culture of the subphrenic drainage will improve the outcome of IPSCH.

Aged↗