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Results for “LEIOMYOSARCOMA”

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At least 1,063 records · Page 59Linked to original sources
PubMed1991

[Leiomyosarcoma of the spermatic cord: a case report].

A 63-year-old man presented with painless hard swelling of left scrotal contents. Left orchiectomy with high ligation of the spermatic cord was done with clinical diagnosis of testicular tumor. Histopathologically, this tumor was diagnosed as leiomyosarcoma, primarily, arising from the spermatic cord. After operation, prophylactic radiotherapy (60Co, 5,890 rad) was given locally. There has been neither local recurrence nor metastasis for 10 months after operation. This is the 18th case of leiomyosarcoma of the spermatic cord in Japan.

Combined Modality Therapy↗
PubMed1991

[Leiomyosarcoma of the larynx. Histological, immunohistochemical and ultrastructural study of a case with review of the literature].

Laryngeal leiomyosarcoma: histological, immunohistochemical and ultrastructural study of one case with review of the literature. Leiomyosarcoma of the larynx have rarely been reported and a review of the literature has yielded only 8 cases. Authors report a case in a 45-year-old patient. Histological exam of the surgical specimen showed a malignant spindle cell tumor. Ultrastructurally, neoplastic cells presented some features of smooth-muscle cells. Immunohistochemical studies revealed that most tumor cells coexpressed vimentin and smooth-muscle actin.

Actins↗
PubMedDate not supplied

[Leiomyosarcoma of the inferior vena cava: literature review and surgical treatment. Apropos of 2 retrohepatic localizations].

Two cases of leiomyosarcoma of retrohepatic inferior vena cava are reported. The two patients are women and are currently alive with metastases one, seven years, and the other one year postoperatively. Leiomyosarcoma of inferior vena cava s a rare tumor which has an unexplained predilection for women. Clinical symptoms are non specific and depend mostly on the segment of the vessel involved. Preoperative diagnosis is based on ultrasonography, computed tomography and cavography. Although the prognosis is poor due to local recurrence and metastasis, we recommend an aggressive approach by radical tumor resection and caval reconstruction.

Angiography↗
PubMed1991

Leiomyosarcoma of the left atrium: case report and review of the literature.

Leiomyosarcomas are extremely rare primary cardiac tumours. A 46-year-old woman presenting with symptoms and signs of rapidly progressive left ventricular failure and apparent systemic lupus erythematosus was subsequently found to have a grade III/III left atrial leiomyosarcoma which was confirmed surgically. Pathology showed a cellular neoplasm arranged in fascicles with multinucleated giant cells, with areas of high grade sarcomatous change. The patient died seven months postoperatively with intractable heart failure. At autopsy, tumour infiltrated the pericardium, both atria and the right ventricle, with invasion of the diaphragm and posterior mediastinum. The current world literature is reviewed with respect to this rare and often misdiagnosed tumour.

Female↗
PubMed1990

[Leiomyosarcoma of the uterus--a clinicopathologic analysis of 11 cases].

Eleven patients with leiomyosarcoma of the uterus are analysed clinicopathologically. The youngest patient was 36 and the oldest was 61 with a mean of 50.8 years. The common clinical symptoms were menorrhagia or irregular vaginal bleeding, lower abdominal pain and rapidly enlarging abdominal mass. None was diagnosed before operation for lack of specific symptoms. All tumors with 10 or more mitotic figures (MF) per 10 high-power fields (HPF) were diagnosed as malignant whereas for those with less than 10 MF/10 HPF the diagnosis of uterine leiomyosarcoma must depend on cellular pleomorphism, number of giant cells, increase in nuclear-cytoplasmic ratio and presence or absence of boundary between the tumor and normal tissue. The main treatment was total hysterectomy and bilateral salpingo-oophorectomy. The 2- and 5-year survival rates were 36.3% and 27.3%, respectively. Five cases with Stage III and IV lesions died within 11 months after operation. The clinical stage at the initial treatment is the most important prognostic factor. For tumors confined to the uterus, cellular pleomorphism, mitotic figure and boundary between the tumor and normal tissue are the other important prognostic factors.

Adult↗
PubMed1990

[Primary right atrial leiomyosarcoma in an adult].

Primary leiomyosarcoma of the heart is very rare, and in most cases the diagnosis is performed during postmortem examinations. We report on a 71-year-old woman with a large leiomyosarcoma of the right atrium. The preoperative diagnosis of cardiac tumor was made by 2-D echocardiography, transesophageal echocardiography, computed tomography, and MR-imaging, and was confirmed by histological and immunhistological findings of the resected part.

Actins↗
PubMedDate not supplied

[Leiomyosarcoma of the small intestine in the young adult: unusual diagnostic approach].

The authors report the case of a 40-year-old woman with fever and diarrhoea in whom a tumour of the small intestine was discovered by computerized tomography (CT), the barium meal being not contributory. Transcutaneous fine needle aspiration biopsies under CT guiding revealed a grade II leiomyosarcoma. Twenty months after radical resection, the patient is alive and asymptomatic. The authors review the literature about the histological grading and the immunocytochemical characteristics of leiomyosarcoma, its treatment and prognosis.

Adult↗
PubMed1990

[A case of primary leiomyosarcoma of the lung].

We reported a case of 66-year-old female with leiomyosarcoma of the right lower lobe of the lung with the complaint of abnormal shadow of the chest roentgenogram. On December 2, 1987, partial resection was performed and the tumor was totally removed. Histological examination revealed primary leiomyosarcoma of the lung. By electron microscopic observation, pinocytotic vesicle was not observed, but myofilaments were observed in the cytoplasm.

Aged↗
PubMed1990

[A case of leiomyosarcoma of the small intestine. Clinical and anatomopathologic considerations].

Leiomyosarcoma of the small intestine is a malignant mesenchymal tumour composed of smooth muscle cells from the muscular coat or, rarely, from muscularis mucosae, which in the majority of cases is characterised by a clinically silent development and by an unfavorable prognosis. The considerable difficulty of obtaining a histological definition of the degree of malignancy of the leiomyosarcoma is also typical. The paper reports a clinical case and summarises its main clinical and anatomopathological aspects. In particular, the difficulties of clinical and histological diagnosis of the degree of malignancy are underlined, together with the fact that these have a considerable influence on the possibilities and results of surgical therapy and survival rates.

Female↗
PubMed1990

[A case report of five-year survival with repeated resection of metastases from jejunal leiomyosarcoma].

A case of five-year survival of jejunal leiomyosarcoma with metastases to the liver and mesentery treated with four times surgery was reported here. Four metastatic lesions were detected in the sigmoid mesocolon once and in the liver three times and resected with hope of cure. The patient, a 37 years old male, tolerated surgical procedures including an extended right hepatic lobectomy and recovered each time. He is leading a satisfactory daily life 5 years and 3 months after the initial operation although multiple liver metastases were detected 10 months after the fourth operation. A positive surgical therapy is advocated in selected patients who have spreading leiomyosarcoma of the bowel.

Adult↗
PubMed1990

[Differential diagnosis and analysis of 34 cases with esophageal and cardiac leiomyoma and leiomyosarcoma].

34 cases with esophageal and cardiac leiomyoma and leiomyosarcoma were treated by surgery from Nov. 1955 to Mar. 1988. Two groups, that of the esophagus and that of the gastric cardia were divided. The patients average age is 34.8-year and 51.8-year respectively. The shortest course of the disease is 15-day and the longest one is 12-year. Dysphagia had been the major symptom. 30 cases had single tumor and 4 cases had multiple lesions. Totally 41 tumors were resected, among which the smallest tumor is 0.6 X 0.4 X 0.3 cm, the largest one is 10 X 9 X 7 cm. Diagnostic criteria to differentiate leiomyoma from leiomyosarcoma and these smooth muscle tumors from other diseases were discussed.

Adult↗
PubMedDate not supplied

Leiomyosarcoma metastatic to the brain with prolonged survival.

A case of uterine leiomyosarcoma with cerebral and pulmonary metastasis is presented. The patient underwent chemotherapy and multiple surgical procedures, including three craneotomies for resecting cerebral metastasis. More than four years of survival with good quality of life were obtained. An aggressive surgical therapy in the rare cases of cerebral metastasis of leiomyosarcoma may be justified.

Adult↗
PubMedDate not supplied

Leiomyosarcoma of the lung. Primary cytodiagnosis in two consecutive cases.

Two cases of primary leiomyosarcoma of the lung are described, in which primary cytodiagnosis of the tumor type was established prior to surgery. The cytologic features of the cell samples obtained and correlated histopathologic findings are described. The cytologic features of pulmonary leiomyosarcomas are sufficiently characteristic to allow definitive diagnosis, if representative cell samples are obtained.

Aged↗
PubMed1989

[A case of giant leiomyosarcoma that grew exogastrically in a year and four months].

Presented is a 69-year-old female who had gigantic leiomyosarcoma showing a pedunculated and exogastric growth. Though the patient had been diagnosed as having a gastric submucosal tumor (SMT) on being given an upper GI series and an endoscopical examination, she did not enter hospital until a year and 4 months later. On admission, a large SMT was suspected after an upper GI series and an endoscopic examination. Computed tomography (CT), ultrasonography (US), and angiography revealed a gastric SMT that had grown exogastrically. Subsequently, this tumor was resected with the gastric wall. Histologically, tumor was determined as being a leiomyosarcoma. CT and US were found useful in demonstrating the SMT with its exogastric growth.

Aged↗
PubMed1989

[Case report of a second resection of rectal leiomyosarcoma due to recurrence after 10 years].

A leiomyosarcoma of the rectum is a rare disease, and cases of a recurrence are even more rare. Reported is the case of a patient who, in 1987, underwent a per sacral resection of a rectal tumor which was diagnosed as leiomyosarcoma. In 1987, after symptoms that showed that the patient's feces had become narrower, a recurrence of this tumor was diagnosed, so that the patient again underwent an abdominoperineal rectomy. The postoperative course has been good. Details of this disease still remain unclear. In Japan, there have been only 10 such cases of a recurrence reported. Of these, a liver metastasis and a localized recurrence are the most common. Long term follow-ups are considered necessary.

Aged↗
PubMed1989

[Multiple leiomyosarcoma of the small intestine. Apropos of a case].

The authors report a case of multiple leiomyosarcomas of the small intestine, which is a very exceptional entity. After reviewing the pathological features and the distribution of leiomyosarcomas, they present the radiological and especially the computed tomographic findings of this type of tumour. They stress the difficulty of the differential diagnosis both in the solitary forms and in the exceptional multiple forms.

Aged↗
PubMed1989

[Usefulness of ultrasonography-guided fine needle aspiration cytology in a case of jejunal leiomyosarcoma].

The patient was a 45-year-old man with the symptoms of abdominal pain and constipation. Laboratory data showed no remarkable changes. Ultrasonic and CT-scan examinations revealed a mass deeply situated in the abdominal cavity. Ultrasonography guided needle aspiration cytology was performed. Obtained specimen showed a large cluster accompanied by numerous smaller clusters, and dispersed single cells. Most of cells were spindle in shape with abundant cytoplasm, and uniform in size. These cells have moderately hyperchromatic nuclei with finely granular pattern, which were round or oval, and have tiny nucleoli. Some cells were binucleated. The nuclear membrane was sharp and well preserved. Giant cells or mitotic figures were not observed. As a result, cytological diagnosis was "suspicious of leiomyosarcoma". The tumor was resected. The specimen consisted of a segment of the jejunum with an irregularly-shaped, and reddish soft first-sized mass continued to jejunum muscle layer. The cut surface of the mass showed central cavitation and necrosis in part. Histological diagnosis was well differentiated leiomyosarcoma originated from the jejunum. The tumor was composed of smooth muscle like cells arranged in bundles with some bizarre multinucleated cells and rare mitotic figures.

Biopsy, Needle↗