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At least 1,063 records · Page 59Linked to original sources
PubMed1989

[Significance of HCG injection for ovulation induction and of ovulation prediction factors in the practice of artificial insemination using donor sperm. A randomized study].

This randomised study was carried out on 77 patients who underwent 269 cycles of donor insemination (AID). The randomization was carried out to decide whether HCG should be used or not to provoke ovulation. The results in AID show, in our study, that using HCG in estimating oestradiol makes very little difference. On the other hand, measuring LH and the quality of the sperm that is used for the insemination seem to us to be important, whereas the quality of the cervical mucus is absolutely fundamental. Ultrasound makes it possible to determine the date when the AID should be carried out in difficult cases. The use of HCG to release the oocytes can be discussed when the cervical score is less than 7 when the other parameters are favourable, and in particular when the diameter of the dominant follicle is 18 mm or more. A higher pregnancy rate should be able to be obtained in AID if all parameters are looked at.

Chorionic Gonadotropin↗
PubMed1989

Timing of ovulation for artificial insemination.

Two studies involving eighty women having treatment with artificial insemination by donor (AID) have demonstrated that the use of a urinary semi-quantitative assay for luteinising hormone (LH) gives pregnancy rates comparable to those obtained using plasma LH for the timing of insemination. The advantage of self test assay is evident in a scattered region such as Grampian.

Adult↗
PubMed1989

Attitudinal survey of sperm donors to an artificial insemination clinic.

Donors (n = 42) to an artificial-insemination-by-donor sperm clinic were surveyed to ascertain individual motivations and attitudes regarding participation. Responses were compared to those of a matched control group (n = 50) of nondonors. Donors were motivated by money, with the majority (69%) unwilling to participate if financial incentives were withdrawn. Anonymity was desired, and donors did not favor disclosure of information to a national registry tracking insemination outcomes. However, donors and controls did endorse providing sperm for an infertile brother. Donors and controls differed significantly in response to 2 of 15 questions asked, with differences due to perceptions of donor motivation. Although perceived as altruistic by peers, donors did not envision themselves as such, and most considered donating semen similar to donating blood or organs.

Adult↗
PubMed1989

[Clinical application of intrauterine insemination].

Nineteen infertile couples were treated with intrauterine insemination (IUI) using husband's semen. Three women with asthenospermic husbands, one with unknown cause and one treated with a combination of induced ovulation and IUI conceived. Three healthy infants have been delivered up to now. The indications for IUI, the importance of proper preparation of semen, the technique of insemination and prediction of ovulation in IUI are discussed.

Adult↗
PubMedDate not supplied

[Results of heterologous artificial insemination, ethical- deontological implications].

Fourteen female patients married to infertile men were artificially inseminated with the semen of unknown donors within 1985-1987. Over 150 inseminations (no complications except sporadic pain) produced 7 pregnancies out of which 5 were finished with the delivery of healthy babies, one was terminated in the seventh week with abortion. Fate of the remaining pregnancy is unknown. Ethical-legal implications of AID, the problem of donors and classification of semen, and necessity to store the semen at the temperature of liquid nitrogen due to the risk of AID are emphasized.

Abortion, Spontaneous↗
PubMedDate not supplied

Ureaplasma urealyticum in semen for artificial insemination: its effect on conception and semen analysis parameters.

Semen specimens from 24 donors in an artificial insemination program--selected for women whose infertile status was determined to be male factor-related and for whom no female factor could be determined--were cultured for the presence of Ureaplasma urealyticum. A life table statistical analysis indicated that conception did not occur sooner in the U. urealyticum-negative group (n = 14) compared with those women inseminated with the U. urealyticum-containing semen (n = 10). In addition, no significant differences were detected in semen analysis count, grade, or motility between semen with or without U. urealyticum. We found no differences in the occurrence of fetal morbidity or mortality in ten conceptions between the women impregnated with Ureaplasma-positive (n = 14) and Ureaplasma-negative (n = 6) semen. Thus, our study does not support the role of U. urealyticum as a cause of male factor-related infertility or early pregnancy loss.

Actuarial Analysis↗
PubMed1987

Sperm processing and intrauterine insemination for oligospermia.

The success of IVF has led to the adaptation of IVF sperm processing methods for WIUI. When WIUI is used for treating oligoasthenospermia, there is a theoretical advantage because an isolated population of only the most motile, capacitated sperm are placed directly into the wife's uterus. The cervix and its mucus are bypassed, which may provide a mechanical or biochemical advantage for semen from subfertile males. Removal of seminal plasma (and prostaglandins contained therein) prevents the painful uterine contractions that can occur when raw semen is placed directly into the uterine cavity. The disadvantages of WIUI are related to its expense, problems with precise timing of ovulation, and the frustration that can occur when inseminating personnel are not available whenever ovulation occurs on weekends or holidays. Only truly committed couples who will try WIUI for multiple cycles should be selected for this method of infertility treatment. Although male-factor infertility currently is one of the main indications for WIUI, the widely variable pregnancy rates reported with WIUI leave some doubt regarding its ultimate role in the treatment of this condition. Our own preliminary results with WIUI for treatment of asthenospermia, oligoasthenospermia, and "cervical factor" infertility are encouraging, although the numbers of patients are small. We anticipate that with further refinement of methods of sperm processing and with the newer improved methods of home monitoring of ovulation, these results may improve. Factors that determine pregnancy rates of WIUI for the treatment of oligoasthenospermia are numerous. The degree of oligospermia and/or asthenospermia, the cooperation and persistence of the couple through the required cycles of WIUI (drop-out rate), the method and meticulousness of sperm processing, the accuracy of monitoring ovulation, the availability of insemination personnel whenever ovulation occurs (even on weekends and holidays), and possibly the duration of infertility will all play a role in the ultimate success of WIUI programs. Couples selecting WIUI must be aware that it does not now offer a high pregnancy rate when used for treatment of male-factor infertility. The apparent increased pregnancy rate of WIUI compared with other methods of AIH may have resulted from modern methods of monitoring ovulation. Studies have not yet been performed to show whether comparable pregnancy rates would be obtained if similar methods of monitoring ovulation were used with cervicovaginal methods of AIH. We believe the only clear indication for WIUI now is an abnormal sperm-cervical mucus interaction.(ABSTRACT TRUNCATED AT 400 WORDS)

Female↗
PubMed1985

Psychological and attitudinal profiles in donors for artificial insemination.

Few objective data are available concerning the psychological profiles and attitudes of sperm donors in artificial insemination programs. We studied 30 consecutive new volunteers and 45 established sperm donors using the Cattell 16PF personality profile and an attitudinal survey concerning motives for donation, attitudes toward uses of sperm, desire for knowledge of outcomes, and attitudes toward disclosures of identifying and nonidentifying information between the parties to artificial insemination. Donors differed from the population norms in 7 of 16 first-order and 1 of 4 second-order personality factors, and this difference appeared to reflect their self-selection as donors. The predominant motive for donation was altruism, but secondary motives were also common. Financial motivation was very low in this population with few students. Donors approved of all current and most hypothetical uses of sperm but were not in favor of disclosures of information to other participants in the program. Restriction of disclosures to nonidentifying details was more acceptable. Unmarried donors were more often motivated for nonaltruistic reasons and were more in favor of disclosures. Attitudes of sperm donors were mostly stable over at least 3 years, but an increasing minority with time envisaged circumstances that might lead to their withdrawal from the program.

Attitude↗
PubMed1978

[A contribution to the problem of heterologous insemination (author's transl)].

The problem of a heterologous insemination must occasionally be dealt with. The conditions for such treatment are not good in the Federal Republic of Germany. This, however, should not negatively influence the quality of the therapy. At least the serologic characteristics of the donor should be known. The impetus for this article was provided by the unsuccessful course of a pregnancy after heterologous insemination in a patient with an established, severe Rhesus incompatibility.

Blood Group Antigens↗
PubMed1979

The use of donor mucus and insemination for cervical factor.

In a case of infertility due to cervical factor, application of donor mucus into the cervical canal was effective. The donor mucus with the first fraction of the husband's split ejaculate were incubated at 37 degrees C for 20 minutes. The mucus was then introduced into the cervical canal and a cervical cap for insemination was applied. A positive postcoital test was demonstrated after 6 hours. The patient conceived following a second such treatment. Donor cervical mucus aplication and insemination seem to be of value in the treatment of cervical factor.

Adult↗
PubMed1979

[Heterologous artificial insemination (author's transl)].

The indications for insemination, the selection of donor, consultation with the recipient parent and the technique will be described, based on our four-year experience. A description of the examination before the insemination and the results from a small collection of cases will be discussed.

Erythroblastosis, Fetal↗
PubMed1980

Factors affecting donor artificial insemination success rates.

Pregnancy was achieved at least once by 75 of 100 women treated with artificial insemination donor (AID). In all, 94 gestations were recorded, with a mean time to achieve pregnancy of 3.3 cycles. Success rates were studied relative to ovulatory function, cervical mucus parameters, previous reproductive history, and following pelvic surgery. A life-table analysis of conception according to actual inseminations performed during each cycle gave a 61% conception rate within 6 months, including patients who discontinued therapy after only one treatment cycle. Clomiphene citrate was used freely for ovulation induction. These patients took longer to conceive (5.5 cycles), but had an abortion rate similar to that of the general group. An effect of cervical mucus on the time necessary to initiate pregnancy was not demonstrated. Six of seven patients who had undergone reparative surgery for restoration or promotion of fertility conceived. The highest number of conceptions with double AID was found on cycle days 13 and 15.

Adult↗
PubMed1984

[Religion confronting insemination].

The author attempts the difficult task of summarising the attitude of Catholicism, the Protestant religion, Jehovah's Witnesses, the Greek Orthodox and the Jewish Churches, as well as Islam, to artificial insemination, especially by donor. He discusses reasons for forbidding artificial insemination even from the husband because of onanism. He shows that the Protestant religion alone does not object to AIH and that its role as far as AID is flexible. As far as other religions AID is absolutely proscribed.

Belgium↗
PubMed1978

[Disturbances in ovulation following on artificial insemination with donors (A.I.D.) (author's transl)].

The authors report on the results of statistical analysis of temperature curves in 139 patients before artificial insemination from donors (A.I.D.) and in the cycles in which they were inseminated. It appears that frequently the practice of A.I.D. causes ovulation to come early or late. Late ovulation seems to be the most frequent cause of failures which are then considered to be due to "psychogenic sterility".

Female↗
PubMed1978

Homologous insemination.

Between July 1, 1969, and October 31, 1977, 619 patients were evaluated for infertility. Homologous insemination (AIH) was employed in 53 patients, many of whom had other contributory causes of infertility. There have been 14 single pregnancies in 11 women, including 4 spontaneous abortions, 1 ectopic pregnancy, 8 term deliveries, and 1 pregnancy in progress. Twenty women are currently under treatment. Another 16 women had unsuccessful AIH prior to beginning donor insemination. Seven subsequently conceived with donor semen. Specific indications for AIH and the recommended technique are discussed in detail as well as the occurrence and management of concomitant infertility factors in this study group. It is concluded that AIH does have a role in the management of certain infertile couples.

Adult↗
PubMed1976

Fifteen years experience with artificial insemination.

Artificial insemination is today an accepted procedure in circumventing sterility. In recent years this procedure gained much popularity as the number of infants available for adoption steadily decreased due to the liberal abortion laws. A review of 15 years of practiced experience (senior author) is presented. In all described cases (168 women) artificial insemination was performed personally by the author. The high rate of success (80% of the presented cases) is attributed to a very meticulous and highly individualized approach to each case. Review of literature is presented.

Adolescent↗
PubMed1998

Multi-level modelling of conception in artificial insemination by donor.

Data on insemination with donor's sperm have a crossed hierarchical structure due to the coexistence of female factors (ovulatory cycles within pregnancy attempt within women) and male factors (inseminations within donations within donors). A crossed random multi-level logistic model, taking account of this structure, permits an improved estimation of the fixed effects and provides insights into their influence at each level in the hierarchy. We present an efficient algorithm for fitting such models using alternating EM steps. We further discuss the inclusion of compositional covariates to determine what information the quality of a donation conveys regarding the donor basal fecundability and on the specific sperm donation.

Adult↗
PubMed1997

Birth of offspring following artificial insemination in the common marmoset, Callithrix jacchus.

The objective of the study was to develop a method for artificial insemination (AI) in the common marmoset, a New World primate species. For AI to be successful, sperm must be deposited at an appropriate site and time in the female reproductive tract, details of which are currently not available for Callitrichid species. Epididymal sperm were deposited in the cervix of 18 marmoset monkeys (Callithrix jacchus) around the time of expected ovulation using either 3, 2, or 1 inseminations. Six out of 18 females conceived, resulting in the first reported births following AI in this species. These pregnancies show that the presence of coagulum in the vagina and the stimulus of the female reproductive tract by natural mating are not essential for effective sperm transport in this species. Although 3 different timing regimes for sperm deposition relative to ovulation were employed, no protocol was demonstrably better than the others in terms of number of conceptions. The proportions of motile, live, and morphologically normal sperm in the suspensions used for AI were comparable with published values for ejaculates from fertile male macaques. These preliminary results indicate that births are possible following AI in marmosets: the technique could be used to aid effective genetic management of the species and possibly to facilitate captive breeding of endangered Callitrichids.

Animals↗