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At least 1,063 records · Page 59Linked to original sources

Permeation of neoprene protective gloves by acetone: comparison of three different permeation cells in an open-loop system.

The increased interest in protective capacity of chemical protective clothing materials has resulted in an increasing number of reports from permeation testing, performed by various test procedures and with permeation cells of different configurations. To make it possible to compare the resultant data, it is necessary to identify what parameters will have a decisive influence on test results. The influence of various carrier gas flow rates on breakthrough time and permeation rate of acetone through gloves made of neoprene was investigated using three permeation cells of different configurations. The breakthrough times were not influenced by cell design or gas flow rate. On the other hand, both cell configuration and gas flow rate influenced the steady-state permeation rate.

Acetone↗

Permeation testing of protective gloves by using two different permeation cells in an open-loop system (neoprene-toluene).

Two permeation test cells of different sizes were used in a study of the permeation of toluene through two neoprene gloves and special neoprene sheet stock. Three flow rates of the collecting medium through the test cells were used to explore to what extent variation in flow rate would affect the breakthrough times and the steady-state permeation rate. The breakthrough time values were not affected to a significant degree by cell size or by increasing the flow rate of the collecting medium from 60 to 120 mL/min. The steady-state permeation rate values were evidently influenced by the flow rate of the collecting medium and by the size and configuration of the test cell.

Hand↗

Papular-purpuric gloves and socks syndrome associated with acute parvovirus B19 infection: case report and review.

The papular-purpuric gloves and socks syndrome (PPGSS) was first described in 1990. This syndrome is characterized by fever, acral pruritus, edema, petechiae, and oral erosions. Subsequently, parvovirus B19 has been implicated, in most cases, as the causative agent of this syndrome. To date, with two exceptions, all published cases of PPGSS have been from Europe and the Middle East and have been mainly reported in the dermatology literature. Herein, we report what we believe to be only the second case of documented parvovirus B19-associated PPGSS occurring in the United States. The patient presented with the typical clinical syndrome, and the diagnosis of acute parvovirus B19 infection was documented by serial serologies that demonstrated development of IgM antibody to virus during the acute phase of infection and seroconversion to IgG antibody in the convalescent period. We then review the existing literature on this unusual syndrome and its association with parvovirus B19.

Acute Disease↗

Subungual bacteria of the hand: contribution to the glove juice test; efficacy of antimicrobial detergents.

Methodologies for evaluating the efficacy of antimicrobial agents in the bacterial flora of the hand involve variations of the "glove juice" or "sterile bag" procedures. In this study we demonstrate that the subungual flora contribute significantly to the recovery of bacteria in these procedures. Culturing hands that had the subungual spaces sealed with acrylic polish demonstrated a decay type of curve for the number of bacteria recovered in successive samplings with 10(6) colony forming units (CFU) bacteria recovered in the first sampling and 10(3) in the sixth while the opposite hand on which the subungual spaces were not sealed demonstrated a continuous recovery of 10(6) CFU. Serial scrubbings of three minutes with plain detergent, 10% povidone-iodine or 4% chlorhexidine demonstrated a three logarithm reduction for povidone-iodine and four logarithm reduction compared to plain detergent alone for chlorhexidine in hands that had subungual spaces sealed, while the opposite hand showed only a 0.5 to 1.0 logarithm reduction. Povidone-iodine produced a 0.6 logarithm reduction and 4% chlorhexidine or 1.4 logarithm reduction in the density of subungual bacteria.

Bacteria↗

Application of glove designs in resurfacing the dorsum of the hand.

Careful surgery, a precise dressing technique with prolonged immobilization, and the utilization of designs borrowed from the glove industry are integral aspects in our attempts to resufrace the dorsal surface of the hand. One case is presented to demonstrate our method.

Adolescent↗

Purple glove syndrome.

Purple glove syndrome (PGS) often begins with discoloration and progresses to a petechial rash with induration or evidence of infiltration. The etiology of PGS is unknown, although various theories center around i.v. extravasation. We report a case of PGS in a child's foot associated with administration of Dilantin (phenytoin).

Color↗

The juvenile variant of papular-purpuric gloves and socks syndrome and its association with viral infections.

BACKGROUND: Papular-purpuric gloves and socks syndrome (PPGSS) occurs mostly in adults and has been shown to be related to several possible viral infections. However, childhood-onset PPGSS seems to be not so rare as previously thought in our clinical experience. OBJECTIVES: To survey the general characteristics of childhood-onset PPGSS and to determine the possible association between this juvenile variant of PPGSS and various viral infections. PATIENTS AND METHODS: Thirty-three children with erythematopurpuric papular eruptions on the hands and/or feet were enrolled. Detailed history-taking and physical examination were performed on all of them. Blood samples were obtained from 25 patients about 1-5 weeks after the appearance of cutaneous eruptions to check complete blood counts, differential white blood cell counts, and IgM and IgG antibodies to parvovirus B19, cytomegalovirus (CMV), viral capsid antigen of Epstein-Barr virus (EBV) and measles. RESULTS: The median age of these 33 patients was 23 months. The mean duration of the skin eruption was 4.8 weeks (SD 2.7, 95% CI 3.9-5.0). Lymphocytosis was present in 13 patients (52%) while mild eosinophilia occurred in only three patients (12%). Five patients (20%) were positive for IgM antibodies against CMV and seven (28%) were positive for IgM antibodies against EBV. Only one patient (4%) was detected to have IgM antibodies against parvovirus B19. CONCLUSIONS: Childhood-onset PPGSS shows somewhat different clinical features from the adult type. It may represent a nonspecific manifestation of several viral infections, including CMV, EBV and parvovirus B19 infections.

Age of Onset↗

Papular-purpuric gloves-and-socks syndrome.

BACKGROUND AND OBJECTIVE: Papular-purpuric gloves-and-socks syndrome (PPGSS) is a recently described dermatosis in which human parvovirus B19 (HPV B19) has been implicated as etiologic agent; however, it is suspected that PPGSS may be caused by various agents. This study was designed to survey the general characteristics of PPGSS and to determine the role of HPV B19 in its etiology. METHODS: We analyzed data from 21 patient and examined serum samples from three new cases for various viruses. RESULTS: The PPGSS displays a striking uniform clinical pattern. Histologic and immunofluorescence findings are non-specific. Seroconversion of HPV B19 was reported in six cases and confirmed in two of our patients. In only one case was a possible causative role of Coxsackie virus B6 suggested consistently. CONCLUSIONS: The PPGSS represents a distinctive dermatosis and a manifestation of HPV B19 infection. Unlike erythema infectiosum, anti-HPV B19 antibodies seem to develop later after onset of the skin eruption and while viremia is still present.

Adolescent↗

Simultaneous occurrence of pure red cell aplasia and papular-purpuric 'gloves and socks' syndrome in parvovirus B-19 infection.

Papular-purpuric 'gloves and socks' syndrome (PPGSS) has been associated with parvovirus B-19 infection. We report a case of an adult immunocompetent male who presented with PPGSS. Bone marrow examination revealed pure red cell aplasia. Parvovirus B-19 DNA was detected by polymerase chain reaction in the patient's serum, whole blood and in the cutaneous lesions. This report illustrates the variety of clinical manifestations caused by B-19 infection, presents for the first time the concurrent appearance of pure red cell aplasia and PPGSS in the same patient and, finally, suggests that PPGSS may be due to direct lytic effect of the virus.

Adult↗

Nickel penetration through rubber gloves.

Positive patch tests confirm nickel penetration through rubber gloves. Dimethylglyoxime (DMG) results indicate that nickel reactivity may occur where DMG testing is negative.

Absorption↗

Protective effect of gloves--compiled in a data base.

In order to be able to give up-to-date and relevant information to those who have to choose and recommend suitable protective gloves, a data base has been developed containing test data on protective effects against chemicals. Permeation data, clinical as well as experimental, have been collected and, after dermatological assessment, inserted into different files in a microcomputer.

Dermatitis, Contact↗

Simulation of a cold-stressed finger including the effects of wind, gloves, and cold-induced vasodilatation.

The thermal response of fingers exposed to cold weather conditions has been simulated. Energy balance equations were formulated, in a former study, for the tissue layers and the arterial, venous, and capillary blood vessels. The equations were solved by a finite difference scheme using the Thomas algorithm and the method of alternating directions. At this stage of development the model does not include any autonomic control functions. Model simulations assumed an electrical heating element to be embedded in the glove layers applied on the finger. A 1.3 W power input was calculated for maintaining finger temperatures at their pre-cold exposure level in a 0 degree C environment. Alternate assumptions of nutritional (low) and basal (high) blood flows in the finger demonstrated the dominance of this factor in maintaining finger temperatures at comfortable levels. Simulated exposures to still and windy air, at 4.17 m/s (15 km/h), indicated the profound chilling effects of wind on fingers in cold environments. Finally, the effects of variable blood flow in the finger, known as "cold-induced vasodilatation," were also investigated. Blood flow variations were assumed to be represented by periodic, symmetric triangular waves allowing for gradual opening-closing cycles of blood supply to the tip of the finger. Results of this part of the simulation were compared with measured records of bare finger temperatures. Good conformity was obtained for a plausible pattern of change in blood flow, which was assumed to be provided in its entirety to the tip of the finger alone.

Algorithms↗

[Human parvovirus B19 infection which first presented with petechial hemorrhage, followed by papular-purpuric gloves and socks syndrome and erythema infectiosum].

A case of human parvovirus B19 (B19) infection is reported. A 6-year-old previously healthy girl was admitted to our hospital complaining of slight fever and petechial hemorrhage on her neck, trunk and the proximal parts of extremities. On admission, the platelet count was within normal range (180 x 10(3)/microliter) but white blood cells and reticulocytes were moderately suppressed (2.4 x 10(3)/microliter and 1@1000, respectively). The purpura disappeared in a week and the blood cell counts fully recovered without any specific treatment. Detection of B19 DNA and anti-B19 IgM antibody in the serum on admission led to the final diagnosis. Since the cellular receptor for B19, the blood group P antigen, is expressed on vascular endothelial cells as well as erythroid progenitor cells, the purpura was considered to be the result of direct vascular injury. She was very unique as she subsequently exhibited papular-purpuric gloves and socks syndrome and erythema infectiosum during follow-up. This case may provide a new insight into the pathogenesis of cutaneous manifestations of B19 infection.

Child↗

Transparent plastic incubator for the anaerobic glove box.

An incubator designed for use inside an anaerobic glove box is described. The incubator is made of transparent plastic material, has sliding plastic doors, and can be made in various sizes from readily available materials.

Journal Article↗

Detection of gas leaks in an anaerobic glove box.

An inert gas, Freon, can be added to the atmosphere of an anaerobic glove box without deleterious effect to cultures of anaerobic microorganisms. The sensitive probe of a Halogen Leak Detector passing over the outside surface of the box will pinpoint any escaping Freon and therefore locate the leak.

Anaerobiosis↗

Rapid entry port for an anaerobic glove box.

A rapid entry mechanism for an anaerobic glove box is described. The entry port is practical for entry or removal of one or two items and requires only seconds to operate. No deleterious effect on isolation or growth of anaerobes has been encountered since installation of the rapid entry port 3.5 years ago. Details for its construction are given.

Anaerobiosis↗

Compact anaerobic glove box for hospitals and research laboratories.

An anaerobic glove box designed for moderate-sized hospitals or research laboratories is described. The compact vinyl and metal enclosure becomes anaerobic rapidly after inflation, requires no vacuum pump, and provides incubator space equivalent to 15 standard anaerobic jars.

Anaerobiosis↗