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Data collection and study implementation.

Every step of the research process involves decisions that must be made. In almost all cases, there are many possible choices, and none of them is wrong. However, it is up to the researcher to consider all of the options and systematically eliminate possibilities based on a theoretical framework, previous findings and methods described in the literature, or circumstances specific to each research question. When the methods used are less than ideal for some reason, the researcher should identify the problems as limitations to the study. Sometimes the limitations restrict the population to which the data can be generalized. In other instances, the limitations identify new areas of study that the current investigation did not address, but for which the current data provide support.

Data Collection↗

Prognosis in valvular heart disease. I. Description of purpose, organization, data collection techniques, estimates of statistical power, and criteria for termination of patient entry. VA Cooperative Study Group on Valvular Heart Disease.

This report describes the design of a multicenter study with two major goals: the identification of valvular heart disease patients at risk for death or a serious complication, and the comparison of hemodynamic function and late outcome of a mechanical prosthetic valve (Björk-Shiley) with a bioprosthesis (Hancock porcine heterograft valve). Strengths of the study design are quantitative assessment of valvular and left ventricular function before and 6 months after valve replacement, measurement in a central laboratory of critical data items such as valve orifice area and left ventricular volumes, and assignment of cause of death and valve-related complications by a committee blinded to valve type. Statistical power calculated by a simulation technique shows only modest loss of power with frequent examination of outcome compared to infrequent examination. Guidelines for premature termination of the study because of superiority of one valve type are described; this includes a critical region with a sloping boundary, which allows for greater chance variation early in the study when the number of patients and events is small, gives the greatest statistical power, and yet appears to provide adequate protection for the subjects in the study.

Bioprosthesis↗

[Are data collected in France sufficient for a quantitative analysis of food-related infections?].

International marketing of animals, animal products and food stuffs and the emergence or re-emergence of food poisoning has raised the risk of international transmission of certain infectious agents. Risk analysis, with its three components, assessment, management, and information, constitutes a new approach to state health policies. To guarantee health safety of the human, animal and plant populations, states can prohibit importation or marketing of food products if their decisions are based on open scientific evidence. Risk assessment is a structured open process evaluating available data designed to modelize transmission of the infectious agent integrating the different elements of the food chain from production to consumption. The assessment process involves four phases, The results of risk assessment depend on the pertinence and the quality of the data used for each of these four phases. Data required to implement risk assessment are unfortunately widely dispersed. The food and agriculture industry, official regulatory agencies, consumer watch organizations, and the scientific community all have useful information for risk assessment. The lack of standard methods to collect, process and diffuse data further complicates the problem.

Data Collection↗

The health diary: an examination of its use as a data collection method.

Use of a health diary has been common in nursing practice settings. Nurses have incorporated the diary as a means of helping clients to document their symptoms and factors which may have precipitated them, often with the aim of modifying particular health behaviours. To date there has been limited exploration of this tool in a nursing research context. Advantages and disadvantages associated with the diary when utilized as a research instrument in health settings are summarized and particular consideration is given to their use in nursing research with cancer patients. Features of the method such as completion and respondent co-operation, format and issues surrounding data analysis are considered. The advantages of this method warrant further exploration in nursing research, despite conflicting and insubstantial evidence regarding the feasibility, validity and reliability of specific kinds of information reported in a diary.

Data Collection↗

Perceptual bias in speech error data collection: insights from Spanish speech errors.

This paper studies the reliability and validity of naturalistic speech errors as a tool for language production research. Possible biases when collecting naturalistic speech errors are identified and specific predictions derived. These patterns are then contrasted with published reports from Germanic languages (English, German and Dutch) and one Romance language (Spanish). Unlike findings in the Germanic languages, Spanish speech errors show many patterns which run contrary to those expected from bias: (1) more phonological errors occur between words than within word; (2) word-initial consonants are less likely to participate in errors than word-medial consonants, (3) errors are equally likely in stressed and in unstressed syllables, (4) perseverations are more frequent than anticipations, and (5) there is no trace of a lexical bias. We present a new corpus of Spanish speech errors collected by many theoretically naïve observers (whereas the only corpus available so far was collected by two highly trained theoretically informed observers), give a general overview of it, and use it to replicate previous reports. In spite of the different susceptibility of these methods to bias, results were remarkably similar in both corpora and again contrary to predictions from bias. As a result, collecting speech errors "in the wild" seems to be free of bias to a reasonable extent even when using a multiple-collector method. The observed contrasting patterns between Spanish and Germanic languages arise as true cross-linguistic differences.

Adult↗

Bridging the digital divide: aspects of computerized data collection and analysis for language professionals.

Recent technological developments have made inexpensive digital speech recording and analysis available to any researcher interested in using them. This paper explores the benefits of working with digital sound files, it provides the reader with system recommendations, explains how to digitize audio recordings, and includes suggestions for selected uses.

Biophysical Phenomena↗

Daily events and mood state among individuals living with HIV: examination of the within-persons approach to data collection using daily diary methodology.

Studies examining the link between stressful events and coping with HIV have relied on a between-persons approach focusing on how individuals differ on some characteristics. Although the between-subjects approach has yielded important information, our goal was to use a within-persons approach, making repeated measurements of the same persons over many days, to examine the impact of changing circumstances on the mood states of those with HIV. A second goal was to determine if asking participants to report their daily experiences via a computerized interactive voice system is a viable way to collect such information. This study collected a variety of trait measures for seven HIV patients and subsequently used a computerized telephone system to collect information regarding daily events and mood states over 21 consecutive days. Several daily measures, including self-esteem, optimism, and positive social interactions were significantly related to daily mood states. Trait measures, with the exception of symptom distress, were ineffective in predicting variations in daily mood states. It was concluded that a computerized telephone system is a viable means of collecting information from HIV patients on a daily basis and within-persons methodology may provide useful information about daily events affecting mood states beyond that generated by a between-persons approach.

Adaptation, Psychological↗

The learning curve: the advantages and disadvantages in the use of focus groups as a method of data collection.

Focus groups are not simply a discussion between people, but are focused interviews exploring interactions between participants. In this paper, Ian Mansell, Glynis Bennett, Ruth Northway, Donna Mead and Laurie Moseley explore the complexities and practicalities of using focus groups in research, with reference to a study of palliative care services.

Attitude of Health Personnel↗

[Classification and data collection of the results of paranasal sinus surgery].

In recent years, many techniques for endonasal microsurgery and endoscopic sinus surgery have been developed. This has led to problems in using pathologic findings and reporting results obtained with these procedures. In this article we propose a classification system to eliminate the problems of correlation, standardization and interpretation of the results of paranasal procedures.

Data Collection↗

Surveying board and care homes: issues and data collection problems.

National information is seriously lacking concerning the number and types of board and care homes, their residents, and the quality of services provided. Shortcomings in current living arrangement classification procedures used in federal surveys are critically examined. A definition and classification system is proposed that would transcend state and local government differences caused by differences in licensure and regulations.

Aged↗

Data collection in the clinic.

Important contributions to the understanding of rheumatic diseases can be made by clinicians in university and nonuniversity settings performing research as part of ordinary patient-care activities. This article describes in detail cost-effective methodologies that have been used to develop successful, longitudinal research and clinical care databanks. Specific forms and detailed recommendations are also included.

Ambulatory Care↗

Crystallization, data collection and phasing of infestin 4, a factor XIIa inhibitor.

Infestin is a protein from Triatoma infestans (kissing bug) composed of seven Kazal-type domains that is further processed to yield several serine protease inhibitors with varying specificities. Infestins 3 and 4 are the last two domains of the infestin gene and are found in vivo in the insect's anterior midgut. The last domain, infestin 4, has been cloned, expressed and purified. Here, the crystallization of infestin 4 using the sitting-drop vapour-diffusion method with PEG 8000 as precipitant is described. Crystals belong to the orthorhombic space group P2(1)2(1)2(1), with unit-cell parameters a = 25.89, b = 45.64, c = 57.41 A. X-ray diffraction data were collected to a maximum resolution of 1.8 A using a synchrotron-radiation source. Initial phases were calculated by molecular replacement using an edited rhodniin molecule as the search model. Structure refinement is in progress.

Animals↗

Evaluating maternity services: how representative are data collected using a pregnancy diary?

As a part of the evaluation of Nottingham's response to the Changing Childbirth initiative, a cohort of pregnant women were asked to complete diaries, recording their perceptions of events and their feelings over the entire pregnancy period. Before the study began, we were concerned that the diary completion rate could be low and that those completing would be unrepresentative of the population. In this paper, we report the nature of responses to the diary and show that these problems were far less serious than was initially expected. A high degree of coverage was achieved, implying that large numbers of women were sufficiently motivated to maintain detailed records over many months. The research suggests that the diary is a viable method of data capture in such circumstances.

Adult↗

A linear model method for rank measures of association from longitudinal studies with fixed conditions (visits) for data collection and more than two groups.

Several statistical methods are available for the analysis of responses with ordinal categories or continuous distributions for the respective visits in longitudinal studies. This paper discusses an alternative nonparametric strategy for studies with more than two groups through Mann-Whitney rank measures of association for all pairs of groups. The proposed method is based on U-statistic theory, and it applies a linear or linear logistic model to the Mann-Whitney estimators for the probabilities of better response for each group relative to each of the others. In addition, the ways of adjusting for covariables and managing stratification factors are explained. Analysis of parallel dose-response relationships for two treatments is illustrated for the proposed method with data from a multicenter study with repeated measurements. A nonparametric estimator for relative potency is provided from the method.

Algorithms↗

[Data collection in nursing: report of a teaching experience].

After courses of Assessment of Adults questionnaires were sent to 84 nurses in order to know if their practice of physical examination was modified by them. These nurses worked in different hospitals and graduated schools. The majority of them related that they improved their knowledge about the matter and modified their practice.

Adult↗

VHA, Inc., introduces new data-collection tool allowing national and regional comparisons in real-time.

VHA, Inc., has rebuilt its online comparative clinical measurement (CCM) tool to help get hospital members on the same page in terms of clinical measurement in real-time. In June, it introduced a new version (CCM 2005) that includes the six new clinical goals or "changes of care" outlined late last year by the Institute for Healthcare Improvement in its 100,000 Lives campaign.

Benchmarking↗

Direct comparison of kinematic data collected using an electromagnetic tracking system versus a digital optical system.

The purpose of this study was to quantify the dynamic accuracy of kinematics measured by a digital optical motion analysis system in a gait analysis laboratory (capture volume approximately 20m(3)) compared to a standard range direct-current electromagnetic (EM) tracking device (capture volume approximately 1m(3)). This is a subset of a larger effort to establish an appropriate marker set for the optical system to quantify upperlimb kinematics simultaneously with gait, in comparison to previous studies of isolated upperlimb movements that have employed EM tracking devices. Rigid clusters of spherical reflective markers and EM sensors were attached to a mechanical articulator that mimicked three-dimensional joint rotations, similar to the elbow. As the articulator was moved through known ranges of motion (i.e. gold standard), kinematic data were collected simultaneously using both tracking systems. Both systems were tended to underestimate the range of motion; however, the application of post hoc smoothing and least-squares correction algorithms reduced these effects. When smoothing and correction algorithms were used, the magnitude of the mean difference between the gold standard and either the EM or optical system did not exceed 2 degrees for any of the compound motions performed. This level of agreement suggests that the measurements obtained from either system are clinically comparable, provided appropriate smoothing and correction algorithms are employed.

Algorithms↗