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[Phytotherapy in chronic dermatoses and wounds: what is the evidence?].

Phytotherapeutic preparations and synthetic derivatives of plant origin have been used in conventional dermatology for a long time. A further spectrum of phytotherapeutic agents for the treatment of dermatological diseases and wounds is known from alternative medical treatment. To the efficacy of these phytotherapeutic agents only few data from studies are available. Own studies and studies published in the specialist literature, especially on chamomile, arnica, calendula, hamamelis, Aloe vera, cardiospermum, Mahonia aquifolium, oak bark, bittersweet stalk, and capsaicin indicate that these plants may be of value in selected dermatological indications. Other controlled clinical efficacy studies and pharmacological studies are needed to prove the assumed effects, to record the spectrum of side effects, and to clarify the mechanisms of action.

Chronic Disease↗

Vulvar dermatoses--irritant and allergic contact dermatitis of the vulva.

Irritant and allergic contact dermatitis are commonly seen in patients complaining about itching, burning and irritation in the vulvar area. Irritation often precedes allergic sensitization. Clinically, irritant and allergic contact dermatitis can be difficult to distinguish. Diagnosis is made by history, clinical investigation and patch testing. Recommended patch test series are the standard series, a medicament series, the patient's own topical medicaments, popular remedies and other suspected products. A skin biopsy may be useful to establish the diagnosis of contact dermatitis, but it is usually not helpful for the differential diagnosis between irritant and allergic dermatitis.

Allergens↗

'Patient's delay'--analysis of the preclinical phase of occupational dermatoses.

BACKGROUND: In order to cure diseases effectively it is important that they are detected in their early stages so that medical precautions can be taken. With job-related disorders it is conceivable that anxiety concerning the workplace, as well as other factors of a demanding nature, may lead to a further delay of diagnosis and treatment. OBJECTIVE: The study was carried out for the purpose of gathering information about the patients' reactions in the preclinical phase of job-related eczema. METHODS: 79 patients suffering from a job-related skin disease were questioned. The patients were divided up into groups according to their respective delay and the results evaluated in line with the method of logistic regression. RESULTS: The average delay was 8.6 months. Fear of losing their job was mentioned by most participants as the reason for the postponement of seeking medical care. People with a long delay were mainly men, senior and Swiss citizens, those with a higher education and those with a longer professional training. CONCLUSION: Patient delay in occupational dermatology highly depends on the support of employers and on the counseling of workers on job-related skin disease and their insurance protection.

Adolescent↗

Altered capillary response to tape stripping in psoriasis and some other dermatoses: the petechial threshold test.

66 psoriatics, 34 normal adults, 10 normal juveniles, and smaller groups of patients afflicted either with seborrheic dermatitis-rosacea or atopic dermatitis were examined for the threshold of capillary petechia formation on clinically normal forearm skin in response to repeated tape stripping. A definitely lowered petechial threshold was found in psoriatics (mean of 9 vs. 19 tape strips) and also in persons with the seborrheic-rosacea complex. Normal juveniles and patients with atopic dermatitis had an increased threshold. The possible relation of these data are pointed out to recent findings of ultrastructural abnormalities of psoriatic papillary capillaries, and an altered capillary response is suggested as a sine qua non precondition for the development of psoriasis. The petechial threshold test is recommended as a simple adjunct diagnostic tool.

Capillaries↗

Antimicrobial effectiveness of Locacorten-Vioform cream in Secondary infections of common dermatoses.

In a double-blind study involving 430 patients, Locacorten (0.02%)-Vioform (3%) cream was found to be highly effective in the treatment of dermatological conditions complicated by secondary bacterial involvement. Themicrobiological conversion and clinical improvement in patients treated with Locacorten-Vioform combinations were markedly greater than those achieved in the groups medicated with (1) Vioform 3%, (2) Locacorten 0.02%, and (3) placebo cream. Staphylococcus aureus was the most prevalent organism isolated from the skin lesions. All strains were sensitive to Vioform, as compared to 62% found to be resistant to other antimicrobials.

Administration, Topical↗