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PubMed2003

Automobile seat comfort: occupant preferences vs. anthropometric accommodation.

Automobile seat design specifications cannot be established without considering the comfort expectations of the target population. This contention is supported by published literature, which suggests that ergonomics criteria, particularly those related to physiology, do not satisfy consumer comfort. The objective of this paper is to challenge ergonomics criteria related to anthropometry in the same way. In this context, 12 subjects, representing a broad range of body sizes, evaluated five different compact car seats during a short-term seating session. Portions of a reliable and valid survey were used for this purpose. The contour and geometry characteristics of the five seats were quantified and compared to the survey information. Discrepancies were discovered between published anthropometric accommodation criteria and subject-preferred lumbar height, seatback width, cushion length, and cushion width. Based on this finding, it was concluded that automobile seat comfort is a unique science. Ergonomics criteria, while serving as the basis for this science, cannot be applied blindly for they do not ensure comfortable automobile seats.

Analysis of Variance↗
PubMed2003

The 3D scanner for measuring body surface area: a simplified calculation in the Chinese adult.

Three-dimensional (3D) surface anthropometry enables us to extend the study to 3D geometry and morphology of mainly external human body tissues. A model is presented for estimation of human body surface area (BSA), which is identical in form to the one proposed in 1916 by DuBois and DuBois is presented. The purpose of this study is to measure BSA, using 3D scanner, and to derive a simple BSA estimation formula for the Chinese adults. In as little as 12s, the Chang Gung Whole-Body Scanner (CGWBS) allows you to capture the shape of the entire human body. The total error in BSA measurement due to scanning measurement and software computational error is less than 1%. The 3D anthropometric measures in a healthy population (n=3951) were investigated, and the results were used to derive a BSA estimation formula. The results seem to be comparable to previous data that measured BSA using traditional methods. The BSA estimation model of this study also validated using 300 new measurements along with the formulae proposed in previous researches. The result suggests that our formula better fits our adults.

Adult↗
PubMed1998

Anthropometric variability, equipment usability and musculoskeletal pain in a group of nurses in the Western Cape.

This study examined the anthropometry and anthropometric fit of a group of nurses in Western Cape private hospitals. Anthropometric variables were measured using a sample of nurses and a correlation matrix generated. All nurses were given a questionnaire concerned with operational problems in the work environment and musculoskeletal pain. The nurses reported numerous problems in the working environment, including lumbar backache, inadequate space and equipment that caused bodily discomfort. There were consistent, statistically significant associations between the frequency of occurrence of these problems and the anthropometric data indicating that the problems were caused or amplified by body size variability and were not simply general usability problems which would affect all nurses irrespective of their body dimensions.

Adult↗
PubMed2001

Postprandial lipid metabolism and insulin sensitivity in young Northern Europeans, South Asians and Latin Americans in the UK.

The aim of this study was to determine whether the higher susceptibility to coronary heart disease and diabetes in South Asian immigrants to the United Kingdom compared with the Caucasian population may reflect insulin resistance and altered postprandial lipid metabolism. We also wished to study Latin Americans, an ethnic group that has not been previously studied in the United Kingdom. The intention was to carry out a detailed study in a relatively small number of subjects to provide essential baseline information for larger epidemiological studies. Postprandial lipaemia was measured in 25 subjects (eight South Asians, eight Latin Americans and nine Northern Europeans) who resided in the United Kingdom. Results from the postprandial studies were correlated to insulin sensitivity measured by the insulin tolerance test, food intake, anthropometry and adipose tissue fatty acid composition. In South Asians, postprandial glucose and insulin concentrations were greater than in the other groups (P<0.01 and <0.05, respectively), although there were no differences in postprandial triacylglycerol concentrations or in insulin sensitivity assessed with the insulin tolerance test. The decreased glucose tolerance in this group could not be explained by differences in percentage body fat, body mass index, or by dietary intake measured by food records or adipose tissue fatty acid composition. We conclude that postprandial lipaemia is not affected in young South Asians compared to Northern Europeans although glucose intolerance is detectable. The results from the present study should help in the design of further postprandial lipid studies in different ethnic groups.

Adipose Tissue↗
PubMed2003

C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups.

Inflammatory processes, marked in part by the acute phase reactant C-reactive protein (CRP) and insulin resistance are implicated in atherogenesis. Low insulin-like growth factor-I (IGF-I) and IGF binding protein-1 (IGFBP-1) concentrations are closely associated with insulin resistance. We examined CRP in ethnic groups with differing risk for cardiovascular disease and type 2 diabetes and its relationship with insulin sensitivity (Homeostasis model assessment (HOMA)-S) and the IGF system. European (n=155), Pakistani (n=108) and African-Caribbean (African Caribbean) (n=177) origin participants were randomly sampled from population registers. All underwent basic anthropometry, glucose tolerance testing and measurement of insulin sensitivity, CRP and other metabolic variables. CRP was significantly lower in African Caribbean men and women than in other ethnic groups. Across all groups CRP correlated negatively with (HOMA-S) (rho=-0.29, P<0.001). Regression analysis which included ethnicity and body mass index (BMI) showed that low HOMA-S (beta=-0.17, P<0.001) and low IGFBP-1 (beta=-0.14, P<0.001) were independently and inversely associated with CRP, but the effect was modified by obesity. In obese subjects insulin sensitivity was not associated with CRP. However, for the whole population, a 2.7 mg/l increase in CRP was associated with a 50% (95% confidence interval (CI) 10-210%) greater risk of WHO defined metabolic syndrome, independent of IGF-I (odds ratio (OR) 0.46 (95% CI 0.22-0.96)), IGFBP-1 (OR 0.58 (0.44-0.76)), female sex (OR 0.43 (0.22-0.84)), NEFA (OR 1.06 (1.03-1.09)) and Pakistani ethnicity. High CRP (as a measure of chronic subclinical inflammation), low IGF-I and low IGFBP-1 are independently associated with the presence of the metabolic syndrome and with insulin resistance. In obese subjects insulin sensitivity is not associated with changes in CRP whilst in non-obese subjects CRP independently contributes to variation in HOMA-S.

Age Factors↗
PubMed2004

[Malnutrition in hospitalized patients: prevalence and economic impact].

BACKGROUND AND OBJECTIVE: Malnutrition constitutes a serious problem of public health. We intended to know the prevalence of undernourishment in our hospital, as well as to assess the expenses generated by its presence. PATIENTS AND METHOD: A study of cohorts was designed to evaluate the nutritional state of randomly selected patients admitted to a third level hospital. We carried out a protocol of nutritional evaluation and quantified the associated costs including drugs, diet, and hospital stay according to diagnosis-related groups. RESULTS: In agreement with anthropometry and the index of corporal mass, the prevalence of malnutrition was 0.3% and 13.4%, respectively. When analyzing the biochemical markers, the prevalence rose to 65.7%. Patients with malnutrition at the time of admission underwent a 59.9% deterioration of their nutritional state. An increase of costs was observed in relation to the length of hospital stay (68.04% compared with normo-nourished patients). Costs related to consumption of medicines, especially antibiotics, were also higher, as well as costs related to nutritional support. CONCLUSIONS: Malnutrition is a phenomenon frequently observed in a hospital setting. Malnutrition associated costs are significant.

Anthropometry↗
PubMed2000

Influence of age on the thermic response to caffeine in women.

The purpose of this study was to examine age-related differences in the magnitude of caffeine-induced thermogenesis and the relationship of aerobic fitness, body composition, and hormone and substrate concentrations to the thermic effect of caffeine in younger and older women. Using a placebo-controlled, double-blind study design, 10 older (50 to 67 years) and 10 younger (21 to 31 years) healthy women who were moderate consumers of caffeine (self-reported intake: younger, 139 +/- 152 mg/d; older, 204 +/- 101 mg/d, NS, mean +/- SD) were characterized for fasting plasma glucose, insulin, free fatty acid (FFA), and caffeine levels, energy expenditure, body composition, anthropometry, aerobic fitness, physical activity, and energy intake. Before and after placebo and caffeine ingestion (5 mg/kg fat-free mass [FFM]), the following variables were measured: fasting plasma glucose, insulin, FFA, and energy expenditure, plasma glucose, insulin, and FFA, and energy expenditure in response to placebo and caffeine ingestion. Caffeine ingestion resulted in similar increases in younger and older women for plasma caffeine (younger, 80 +/- 34 to 5,604 +/- 528 ng/mL, P < .01; older, 154 +/- 134 to 5,971 +/- 867 ng/mL, P < .01) and fatty acids (younger, 294 +/- 118 to 798 +/- 248 micromol/L, P < .01; older, 360 +/- 180 to 727 +/- 310 micromol/L, P < .01), whereas plasma insulin and glucose levels remained unchanged from baseline. Energy expenditure increased following caffeine ingestion in both groups (younger, 15.4%, 1.09 +/- 0.14 to 1.24 +/- 0.13 kcal/min, P < .05; older, 7.8%, 0.98 +/- 0.14 to 1.06 +/- 0.12 kcal/min, P < .05), although there was a blunted thermic response in the older versus younger women (older, 6.9 +/- 5 kcal/90 min; younger, 15.5 +/- 7 kcal/90 min, P < .05). In younger women, the thermic response to caffeine was positively correlated with the waist circumference (r = .70, P < .05) and body weight (r = .91; P < .01), whereas aerobic fitness (r = .77; P < .05) was the only significant correlate in older women. In conclusion, older and younger women increase energy expenditure significantly following caffeine ingestion, but older women have a blunted thermic response compared with younger women. Second, the thermic response to caffeine is positively associated with the body weight and waist circumference in younger women, whereas a positive association with aerobic fitness was observed in older women. Thus, the physiologic determinants of the thermic response to caffeine differ among women of different age groups.

Adolescent↗
PubMed2003

Influences of apolipoprotein E polymorphism on the response of plasma lipids to the ad libitum consumption of a high-carbohydrate diet compared with a high-monounsaturated fatty acid diet.

The purpose of this study was to assess the contribution of the apolipoprotein E (apoE) polymorphism and factors, such as age and waist circumference, to variations in plasma low-density lipoprotein-cholesterol (LDL-C) response following ad libitum consumption of a diet rich in complex carbohydrates (high-CHO: 58% of energy as CHO) versus a diet rich in fat and monounsaturated fatty acids (high-MUFA: fat, 40% of energy and 22% as MUFA). Sixty-five men participated in this parallel 6- to 7-week study involving either a high-CHO or a high-MUFA diet. Fasting plasma lipid profile and anthropometry were determined at the beginning and at the end of the dietary period. The high-CHO and high-MUFA diets both induced significant (P<.01) and comparable reductions in body weight and waist circumference. These changes were associated with a significant (P<.01) and comparable decrease in LDL-C (-19% and -16%, respectively). Stepwise multiple regression analyses showed that 32% of the variation in the LDL-C response to the high-CHO diet was attributable to the apoE polymorphism (18.5%, P=.04) and waist circumference (13.5%, P=.03) indicating that men with a waist circumference greater than 100 cm and the E2 allele had the greatest reduction in plasma LDL-C after the high-CHO diet. On the other hand, in the high-MUFA group, waist circumference was the only significant contributing factor to the LDL-C response and accounted for 44.5% of its variance. In conclusion, the plasma LDL-C response to ad libitum comsumption of a high-CHO and a high-MUFA diets are not modulated to the same extent by the apoE polymorphism and waist circumference.

Adult↗
PubMed1997

Determinants of sex hormone-binding globulin blood concentrations in premenopausal and postmenopausal women with different estrogen status. Virgilio-Menopause-Health Group.

In women, sex hormone-binding globulin (SHBG) concentrations are the result of a balanced effect of stimulatory and inhibitory factors. Estrogens represent the principal stimulatory hormones, whereas androgens, insulin, excess body fat, and the pattern of body fat distribution have inhibitory effects. Menopause is characterized by major changes in blood sex steroid concentrations, notably a marked reduction of estradiol levels. In this study, we therefore investigated the relationship between hormonal and nonhormonal regulatory factors of SHBG and its blood levels in two groups of premenopausal and postmenopausal women characterized by normal-high or reduced estrogen concentrations. The data were obtained from an analysis of the cross-sectional database obtained during the first survey of the Virgilio-Menopause-Health Project, an epidemiologic longitudinal study aimed at investigating the impact of menopause on body weight, fat distribution, and related major metabolic, hormonal, and cardiovascular risk factors. A total of 329 women, 133 in premenopause and 196 in postmenopause without diabetes, thyroid diseases, or relevant cardiovascular, renal, and hepatic dysfunction, were included in the study. A clinical history (including dietary and physical-activity habits), anthropometry (body mass index [BMI], waist to hip ratio [WHR], and bioelectrical impedance analysis [BIA]), and morning blood samples in the fasting state for sex hormones, insulin, and biochemistry were available for all the women. Premenopausal and postmenopausal women showed no significant difference in SHBG concentrations (38.7 +/- 17.9 v 36.6 +/- 17.5 nmol/L, respectively). On the contrary, postmenopausal women were characterized by a marked reduction of estradiol levels and significantly lower levels of testosterone. After adjusting for age, insulin was lower and the glucose to insulin ratio was higher in postmenopause than in premenopause. Age-adjusted values for all anthropometric parameters were not significantly different in the two groups. In simple correlation models, SHBG was significantly and negatively correlated with BMI, WHR, and insulin and testosterone levels in both premenopausal and postmenopausal women, whereas estradiol levels correlated positively and significantly with SHBG only in the premenopausal group. A significant positive correlation between the glucose to insulin ratio and SHBG was present in both groups. Using multiple regression models, in the premenopausal group, SHBG levels were correlated positively with estradiol and negatively with testosterone and insulin, but not with the WHR. On the contrary, in the postmenopausal group, SHBG values had a significant negative correlation with the WHR, whereas the relationship with estradiol was not significant; moreover, the relationship with testosterone and insulin, although significant, became less marked. In conclusion, this study indicates that (1) there is no significant difference in SHBG blood concentrations between premenopause and postmenopause; (2) SHBG values are correlated positively with estradiol and negatively with insulin and testosterone concentrations, but the predictive value of these variabiles on SHBG appears to be different in premenopause and postmenopause; and (3) SHBG levels decrease with increasing WHRs, particularly in the postmenopausal group. Therefore, determinants of SHBG blood concentrations are likely to change on passing from premenopausal to postmenopausal status. In particular, there seems to be a threshold level for which estradiol is an important determinant of SHBG blood concentrations.

Adult↗
PubMed1999

Multivariate identification of metabolic features in inflammatory bowel disease.

Weight loss and malnutrition are commonly reported in inflammatory bowel disease (IBD), but differences between Crohn's disease (CD) and ulcerative colitis (UC) patients have rarely been pointed out. In this regard, a sample of 102 consecutive patients with a diagnosis of either CD (n = 63, 33 males) or UC (n = 39, 25 males) based on previously reported clinical, morphologic, and histopathologic criteria were studied. Twenty-six anthropometric and metabolic variables were measured upon admission. Body composition was assessed by both anthropometry and bioimpedance measurements, and energy expenditure and substrate oxidation were assessed by indirect calorimetry. The data were subjected to principal-component analysis and to factor rotation to derive a set of a few basic independent descriptors of the metabolic features of each subject. Six descriptors were found to be responsible for greater than 86% of the total sample variability and to associate very well with mutually disjoint subsets of the original variables. The six summarizing factors are listed in order of decreasing percentage of explained variation (size 41.8%, fatness 17.9%, fuel 12.2%, shape 5.4%, energy 5.2%, and steroid 3.9%). CD and UC patients differed significantly with respect to fatness (CD lower, P = .004) and carbohydrate (CHO) fuel preference (CD lower, P = .030). Hence, CD patients showed a reduced fat mass (FM) compared with UC patients, and from a metabolic point of view, too, CD and UC are not superimposable. In fact, the lower CHO oxidation (CHOox) rate and consequent preferential lipid utilization found in CD patients may be taken into account as a contributing cause of lipid tissue wasting and in planning therapeutic enteral regimens.

Adolescent↗
PubMed2001

Second-trimester placental volume and infant size at birth.

OBJECTIVE: To investigate the ability of second-trimester placental volume measured sonographically to predict birth size. METHODS: A total of 712 women were recruited from the antenatal clinic of the University Hospital of the West Indies; 561 fulfilled the study criteria and progressed to delivery. Placental volume and fetal anthropometry (biparietal diameter, head and abdominal circumferences, and femoral length) were measured sonographically at 14, 17, and 20 weeks. The main outcome measures were infant birth and placental weights, length, head, chest, and abdominal circumferences at birth. RESULTS: Placental volume in the second trimester was positively associated with all birth measurements. Of the fetal measurements at 14 and at 17 weeks, head circumference was the strongest predictor of birth weight (B [slope of the regression line] =.095, P =.014 at 14 weeks; B =.118, P =.012 at 17 weeks), but at 20 weeks, abdominal circumference was the strongest. However, at each age, placental volume was the strongest determinant of birth weight, and improved the prediction based only on fetal measurements. The odds ratio for low birth weight (under 2500 g) increased by 1.68 (95% confidence interval 1.05, 2.69, P = 0.03) for every standard deviation decrease in placental volume at 14 weeks' gestation. CONCLUSION: The present study suggests that low birth weight was often preceded by small placental volume in the second trimester. Placental volume may be a more reliable predictor of size at birth than fetal measurements, and may be useful in early identification of the fetus at risk in the perinatal period.

Adolescent↗
PubMed1977

Office assessment of nutritional status.

The standard components of nutritional assessment-anthropometry, clinical examination, dietary intake, and biochemical analysis--have been discussed in the context of "office or clinic practice." With appropriate modifications of these tehcniques, nutritional assessment can become a basic and integral part of pediatric care.

Adolescent↗
PubMed1996

Lifecourse exposure and later disease: a follow-up study based on a survey of family diet and health in pre-war Britain (1937-1939).

There is an increasing interest in the origins of adult disease in early life. The elucidation of such explanations of current morbidity and mortality must depend upon the follow-up of previously established cohorts. This paper describes the design of and background to such a follow-up of one of the richest data sources for this type of research: Sir John Boyd Orr's survey of diet and health in pre-war Britain. 1,352 families from 16 centres in England and Scotland were surveyed; 3,762 children aged up to 19 years from these families were examined. Socio-economic information and detailed one week dietary diary records are available for all families. Detailed medical examinations (including anthropometry) were undertaken on children in 14 of the centres. Most of the information is cross-sectional although 1,322 children were examined on two or more occasions one year apart to assess the effects of dietary supplementation. Dietary records were retrieved for 1,343 (99.3%) of the families. Medical examination records were found for 3,560 (94.6%) of the children who were examined in the survey and attempts have been made to trace 4,973 children who were either examined or whose family participated in the dietary survey. The data demonstrate relationships between family food expenditure and height in childhood and housing conditions. Eighty-five per cent (4211/4973) of the children have been traced and flagged on the National Health Service Central Register, Southport. The characteristics of those traced do not differ significantly from those we have been unable to trace although untraced females were slightly heavier. To date 696 (16.5%) of the cohort have died. The cohort will be used to investigate the relationship between diet, nutritional status (height, weight, cristal height), health and social circumstances in childhood, and mortality and morbidity in adulthood.

Adolescent↗
PubMed2003

Body composition in French women 75+ years of age: the EPIDOS study.

BACKGROUND: There are presently no published data on age-related changes in body composition in French individuals older than 65 or 80 years. This paper presents a cross-sectional study of 7518 community-residing French women older than 75 years. METHODS: We examined age differences changes in body composition and anthropometry between age groups (76-80, 81-85, and 86-95 years of age). Whole body composition was estimated using a dual energy X-ray absorptiometry (DXA) scanner. Measurements of appendicular skeletal muscle (ASM) mass and sarcopenia were performed for a subsample of 1321 women. RESULTS: Significant age differences exist in total fat mass and total bone mineral content in elderly women between 76 and 95 years of age. There was also a significant decreased in fat free soft tissue mass from 76 to 85. The decline in fat free mass may be reduced over 85 years of age. The prevalence of low muscle mass, or sarcopenia, increased with age from 8.9 in 76-80 to 10.9% in 86-95 age group, but the difference was not statistically significant. CONCLUSIONS: Interventional programs developed to prevent or reduce sarcopenia would have a better influence on population under 85 years, i.e. when the decline in ASM mass is the most severe. Others longitudinal studies could be performed to confirm our results.

Aged↗
PubMed2003

Does early physical activity predict body fat change throughout childhood?

BACKGROUND: Declining levels of physical activity in the population at large may be responsible in part for the rising rates of childhood obesity. Studies to date, however, have not consistently demonstrated such a protective effect. We used longitudinal data from the Framingham Children's Study (FCS) to address this important question. METHODS: We used 8 years of activity monitoring (Caltrac electronic motion sensors) and repeated anthropometry measures for 103 children to examine the effect of activity on body fat change from preschool to early adolescence. Longitudinal data analysis methods were employed to account for the use of repeated measures on these children. RESULTS: Children in the highest tertile of average daily activity from ages 4 to 11 years had consistently smaller gains in BMI, triceps, and sum of five skinfolds throughout childhood. By early adolescence (age 11), the sum of five skinfolds was 95.1, 94.5, and 74.1 for the low, middle, and high tertiles of activity, respectively (P for trend = 0.045). This protective effect of activity was evident for both girls and boys. CONCLUSION: This longitudinal study adds strong support for the hypothesis that higher levels of physical activity during childhood lead to the acquisition of less body fat by the time of early adolescence.

Adipose Tissue↗
PubMed1985

Do maternal energy reserves limit fetal growth?

Birth weight and maternal anthropometric measurements were made in a sample of 2456 deliveries in a poor, African peri-urban community. Maternal anthropometry was similar to that observed in affluent societies, whereas birth weight was significantly lower, even when adjusted for maternal weight and parity. Moreover, multiple stepwise regression showed that for a given maternal weight, fatter women had smaller babies. This is at odds with the classical hypothesis that a maternal energy deficit limits fetal growth.

Anthropometry↗
PubMed1995

Clinical disorders and pressure-pain threshold of the forearm and hand among automobile assembly line workers.

The prevalence of forearm and hand disorders was examined by questionnaire and clinical examination in 199 automobile assembly line workers and in 186 controls. The pressure-pain threshold, hand grip force and hand anthropometry were also studied. There was an increased prevalence of de Quervain's disease for male automobile assembly line workers, and of carpal tunnel syndrome in female workers. The prevalence of symptoms in the forearm and hand during the last 7 days were twice as high among automobile assembly line workers than controls for both men and women. The occurrence of symptoms in the last 7 days was associated with de Quervain's disease, carpal tunnel syndrome and sick-leave due to forearm or hand problems, and it also influenced activities of daily living. Hand grip strength and anthropometrics were not associated with findings in the clinical examination or the occurrence of symptoms in the last 7 days. Low pressure-pain threshold was not associated with findings in the clinical examination, except for reported occurrence of symptoms in the last 7 days for women. Pressure-pain threshold as an indicator of tissue damage is discussed.

Adolescent↗
PubMed1991

Nutritional assessment of continuous ambulatory peritoneal dialysis patients: an international study.

We examined the nutritional status of 224 patients from six centers in Europe and North America to assess the incidence of protein-energy malnutrition. A "subjective nutritional assessment" was made, using 21 variables derived from history and clinical examination, or anthropometry and biochemistry. Eighteen patients (8%) were severely malnourished, 73 (32.6%) were mildly to moderately malnourished, and 133 (59.4%) did not show evidence for malnutrition. There was a higher incidence of mild to moderate malnutrition in diabetics than in nondiabetics. A statistical analysis identified 12 variables, seven objective and five subjective, that correlated with subjective nutritional assessment. Actual intercenter differences for the incidence of malnutrition were related to patient age, nutritional status at the commencement of continuous ambulatory peritoneal dialysis (CAPD), the length of time on CAPD, and residual renal function. Variables that were most frequently correlated with subjective nutritional assessment and with one another included plasma albumin, mid-arm muscle circumference (MAMC), weight loss, and the clinical judgement of muscle wasting and loss of subcutaneous fat. Loss of residual renal function correlated with muscle wasting and months on CAPD. Our data identified differences between the two sexes. In women there was a trend for more anorexia, greater weight loss from muscle wasting, and a larger decrease in albumin, whereas in men there was a more gradual decrease in nutritional status. Loss of residual renal function contributed to anorexia and symptoms of severe malnutrition.

Adolescent↗