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Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

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At least 1,045 records · Page 58Linked to original sources

Editorial peer review in US medical journals.

This study determined if the process of editorial peer review is the same for all medical journals. Two categories of indexed US medical journals were examined: group 1 consisted mainly of well-known, clinically oriented journals, while group 2 was composed primarily of interdisciplinary or specialized journals. Data were collected through a series of interviews and questionnaires. All 16 group 1 editors or managing editors were interviewed. Questionnaires were mailed to 124 group 2 editors (69.4% were returned). Results showed that, although some of the practices of editorial peer review are the same, the two groups of journals had distinct editorial peer review practices. Group 1 made less use of editorial peer review than group 2 by relying on the editorial staff at several important decision points.

Interviews as Topic↗

Clinical pharmacological evaluation of calcium antagonists and other drugs modifying myogenic tone in essential hypertension.

The factors determining the acute and long-term response to calcium antagonists have been studied in controlled trials in essential hypertension. The importance of dose and plasma level in determining the response has been confirmed. The blood pressure response has been modelled and mathematically described, with drug concentrations related to blood pressure falls by linear or Emax (maximum fall in blood pressure) models. The acute response predicted the response after 6 weeks of treatment. Neither age nor plasma renin activity independently influenced the response to calcium antagonists. The level of pretreatment blood pressure (starting blood pressure) was positively related to indices of response. In similar studies with other drugs modifying myogenic tone, while vascular reactivity to selective agonists was reduced, enhanced or unchanged, blood pressure falls were related to plasma levels in all cases.

Blood Pressure↗

Profile of the breast center: one year's experience.

The Grant Regional Breast Center (GRBC) has proven to be an effective means to offer radiologic breast exam. Not only has the service been very well received by patients but it has also shown a profit for the institution. The numbers are too small to show that there has been an increase in early screening. The numbers do suggest, however, that there has been an increased access to screening. Hopefully, this increased access and awareness will lead to increased early detection and increased long-term survival.

Breast Neoplasms↗

Health services research as a scientific process: the metamorphosis of an empirical research project from grant proposal to final report.

The process of health services research is rarely examined; attention is usually focused on results and policy implications. Large and small decisions made during the execution of a study, however, can have major impacts on its outcomes. This article describes a project that underwent major changes because of problems discovered in the basic data and threats to the valid interpretation of econometric results uncovered by qualitative case studies. Although the combination of difficulties encountered in this project may be unusual, it is likely that many similar problems and opportunities occur in other empirical studies.

Blue Cross Blue Shield Insurance Plans↗

Journal matters.

Explore the source record for details and available documents.

Authorship↗

A method for estimating the in-house use of the periodical collection in the University of Minnesota Bio-Medical Library.

During two one-week periods in April 1972, information on periodical title and date was gathered from periodicals collected from study and reshelving tables of the University of Minnesota Bio-Medical Library. IT WAS DETERMINED THAT: (1) a few titles accounted for most of the total use; (2) the relationship between age and amount of use of a journal may be described by the equation y = ke(-bx); and (3) the last five years of publication accounted for 58% of the total use.

Libraries, Medical↗

Restricted randomization designs in clinical trials.

Though therapeutic clinical trials are often categorized as using either "randomization" or "historical controls" as a basis for treatment evaluation, pure random assignment of treatments is rarely employed. Instead various restricted randomization designs are used. The restrictions include the balancing of treatment assignments over time and the stratification of the assignment with regard to covariates that may affect response. Restricted randomization designs for clinical trials differ from those of other experimental areas because patients arrive sequentially and a balanced design cannot be ensured. The major restricted randomization designs and arguments concerning the proper role of stratification are reviewed here. The effect of randomization restrictions on the validity of significance tests is discussed.

Clinical Trials as Topic↗

Development of methodologic tools for planning and managing library services. IV. Bibliography of studies selected for methods and data useful to biomedical libraries.

This selective bibliography is intended to serve as a guide to empirical studies reporting data and methods that can be used by medical librarians to assess their own efforts objectively and to improve the effectiveness and efficiency of services they offer. The decision rules that governed selection of items for the bibliography are specified in detail. A total of 178 items published between 1915 and mid-1968 met the selection criteria. The list of items is supplemented by a keyword index derived from titles. Half the items are journal articles; a third of these articles appeared in the Bulletin, and most of the remainder in thirteen other library and information science journals. Most of the non-journal items are technical reports issued by the organization that conducted or sponsored the work. The characteristics of this literature suggest that few medical libraries, unless they are part of a university system that includes the collection of a library or information science school, are likely to have quick access to the literature base needed to support a comprehensive program of self-evaluation studies and the continuing education of their own staff. Regional medical libraries might well undertake to ensure both ready access to, and awareness of, literature on the scientific aspects of librarianship.

Bibliographies as Topic↗