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Nature's medicinal bounty: don't throw it away.

Plant-derived drugs have an important place in both traditional and modern medicine. For this reason a special effort to maintain the great diversity of plant species would undoubtedly help to alleviate human suffering in the long term. Proven agroindustrial technologies should be applied to the cultivation and processing of medicinal plants and the manufacture of herbal medicines.

Humans↗

Community-tailored One Health educational intervention to enhance knowledge and practices for zoonotic disease prevention in rural Thailand: A protocol for a prospective cluster randomised controlled Trial in Chanthaburi, Thailand (Saan Suk trial).

BACKGROUND: Zoonotic infectious disease risk arises at human-animal-environment interfaces where pathogen spillover can occur. Rural communities living in biodiverse settings may experience frequent contact with wildlife and shared environments through livelihoods, food practices, and economic activities. Reducing spillover risk and strengthening pandemic prevention requires both structural and individual-level change. Community-based interventions that promote awareness, risk perception, self-efficacy, pro-environmental behaviour, and safe coexistence with wildlife may support prevention by shifting behavioural determinants of zoonotic disease risk. The Saan Suk intervention was co-developed with rural communities in Thailand using a Human-Centred Design approach and is grounded in the Health Belief Model and One Health principles. The intervention is intended to be feasible, acceptable, and deliverable through Thailand's established Village Health Volunteer (VHV) system. METHODS: This protocol describes a parallel-arm, cluster-randomised controlled superiority trial that will be conducted during July - October 2026, in Chanthaburi Province, Thailand. 24 villages will be equally randomised to the Saan Suk intervention or the current practice (control). In intervention villages, trained VHVs will deliver, once a week over four weeks, a multimodal One Health educational intervention designed to improve knowledge of zoonotic spillover, promote protective behaviours, reduce risky wildlife-related contacts, and support respectful coexistence with wildlife. Trained outcome assessment teams will conduct structured interviews with 42 adult participants per village, yielding a total sample size of 1,008 participants. The sample size was calculated for the primary outcome, accounting for clustering, with 90% power to detect a medium effect size (6 points on the 0-100 knowledge scale) at a significance level of 0.05, accounting for a design effect with an ICC of 0.028. The primary outcome is knowledge of zoonotic spillover, transmission pathways, risk factors, protective and risky behaviours, and safe coexistence with wildlife. Secondary outcomes include attitudes, self-efficacy, preventive and risky behaviours, and reported contacts with major local reservoir hosts. A structured questionnaire was developed, expert-reviewed, and piloted for the outcome assessment. Outcomes will be analysed using mixed-effects regression models with random effects for village and adjustment for relevant pre-specified confounders. Primary analyses will follow the intention-to-treat principle. DISCUSSION: This trial will evaluate whether a co-designed, VHV-delivered One Health educational programme can improve knowledge of zoonotic disease prevention and behavioural determinants in rural communities living in close contact with wildlife and shared ecosystems. If effective and feasible, Saan Suk could inform integration into routine VHV training and community-based zoonotic disease and pandemic prevention strategies. TRIAL REGISTRATION: The Saan Suk trial is registered with the German Clinical Trials Register (DRKS). Registration ID: DRKS00038582; date of registration: 11 May 2026.

Zoonoses↗

Disparities in access to care among rural working-age adults.

CONTEXT: Nationally, minority population disparities in health and in the receipt of health services are well documented but are infrequently examined within rural populations. PURPOSE: The purpose of this study is to provide a national picture of health insurance coverage and access to care among rural minorities. METHODS: A cross-sectional analysis using the 1999-2000 National Health Interview Surveys examined insurance status and receipt of ambulatory care during the past year. Multiple logistic regression was used to measure factors influencing the odds of insurance coverage and a provider visit. FINDINGS: Among rural minority adults, 32% of blacks, 35% of "other" race persons, and 45% of Hispanics were uninsured compared to 18% of whites. Differences in insurance status were not significant for rural blacks and Hispanics after resources such as education, income, and employment were held constant. Examining use, 37% of rural Hispanics and 27% of blacks, versus 20% of whites and 19% of persons of other race, had not made a health care visit in the past year. When resources were held constant, blacks and persons of other race/ethnicity no longer differed from whites, but differences among Hispanics persisted. CONCLUSIONS: A comprehensive approach to the health needs of rural working age adults must consider the unique characteristics of rural communities and populations, requiring cultural as well as financial creativity in the design of health delivery systems. The importance of resources such as education and employment points to the need to link health problems to area-specific rural economic development.

Adolescent↗

Land settlement policies and population redistribution in developing countries: performance, problems and prospects.

The author describes and compares land settlement in various developing countries, focusing on the movement of people to underutilized agricultural areas. "The purpose of this article is fourfold: first, to discuss the performance of settlement programmes, concentrating on the extent to which they have achieved their population redistribution and other objectives; second, to analyse major economic and social problems confronting them; third, to identify factors that have contributed to their success or failure; and, fourth, to assess alternative policy options." This analysis of land settlement programs "suggests that so far they have made no more than a modest contribution to the solution of the problems of population distribution, unemployment and poverty."

Agriculture↗

China's "tidal wave" of migrant labor: what can we learn from Mexican undocumented migration to the United States?

"The purpose of this article is to place Chinese labor migration from agriculture within the context of the literature on labor mobility in developing countries by comparing it to undocumented Mexican migration to the United States. The similarities fall within three general areas: the migration process, the economic and social position of migrants at their destination, and the agrarian structure and process of agricultural development that has perpetuated circular migration. The last section of the article draws upon these similarities, as well as differences between the two countries, to generate predictions concerning the development of labor migration in China."

Agriculture↗

Factors that contribute to the low use of bed nets in a malaria endemic zone of sub-Saharan Africa: a questionnaire survey in a rural population in Zambia.

BACKGROUND: One objective of the World Health Organisation in the Roll Back Malaria initiative is to intensify the use of impregnated bed nets in malaria endemic regions. OBJECTIVES: To investigate knowledge about malaria transmission, awareness of disease prevention by the use of insecticide treated bed nets and current bed net use among hospital users in rural Zambia. DESIGN: A questionnaire survey. SUBJECTS: Relatives of children (six months to five years) admitted to St Francis' hospital in the Eastern Province of Zambia. RESULTS: The majority of those surveyed understood how malaria is transmitted (90.7%), knew the main clinical features of malaria (99.4%) and knew that bed nets are useful in reducing the frequency of getting malaria (98.1%). However, very few of those questioned owned a bed net (27%). This is primarily due to a lack of availability of affordable nets rather than a lack of understanding about their use. CONCLUSIONS: This survey demonstrates a willingness of the participants to purchase subsidised bed nets. We propose that donor provision of affordable bed nets in hospitals and rural health clinics would be a readily achievable method of increasing bed net use in rural Zambia and so help reach this objective of the Roll Back Malaria initiative.

Bedding and Linens↗

Australian rural midwives: perspectives on Continuing Professional Development.

INTRODUCTION: Continuing Professional Development (CPD) provides an important counter to workforce pressures affecting rural midwives; however, there is a lack of information about how rural midwives understand and perceive CPD and how this is situated in the practising and social context. This research aimed to explore rural midwives' experiences and perceptions of CPD in context. METHODS: A qualitative approach gathered focus group data on the beliefs, opinions and perceptions of a total of 52 rural midwives (nine focus groups), across three Australian states: Western Australia, Victoria and Tasmania. The focus groups were taped and transcribed verbatim and data was analysed thematically using an inductive approach, with the aid of an NVivo (QSR Software, Durham, UK) computer program. RESULTS: Four key themes emerged from the data: midwives' views of CPD; their motivations for undertaking CPD; the choices they make around CPD; and how context factors facilitate their involvement in CPD. Congruence with issues evident in the literature were: the difficulties associated with role diversity, the need for acquiring key skills before engaging in CPD, and the importance of a culture supportive of ongoing learning. CONCLUSIONS: CPD can be considered an important strategy for the retention and professionalism of midwives. The study findings helped fill a gap in the literature about rural and regional Australian midwives' perspectives on CPD.

Attitude of Health Personnel↗

Academic nursing practice in rural West Virginia.

This exemplar highlights how a rural academic nursing practice has been effective in facilitating the integration of the tripartite academic role of education, research, and service for one university faculty member. The integration of students into the practice is described. The experience provided them with critical insights into rural academic practice during their delivery of prenatal care services to a vulnerable population of women in rural Appalachia. This exemplar also describes the use of the academic nursing practice as a laboratory both for studying the specific problems of this vulnerable population of women and their families, and testing interventions tailored to the needs of the community. Finally, the other ways the academic nursing practice benefits faculty and students, including integration of educational technology into the practice setting and opportunities for faculty leadership in rural community development, are discussed.

Community Health Centers↗