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Two cases of liposarcoma of the jaws were reported. These appear to be the first cases of their kind in the literature. Pathological and clinical features were discussed. Early diagnosis and radical treatment after accurate histological typing were stressed.
We review a new case of spermatic cord liposarcoma followed over a period of two years. After simple excision and 50 grays of radiotherapy had a local recurrence one year later; the patient a wide radical orchiectomy was then performed. A review of the literature illustrates the various clinicopathological data and their prognosis. The various treatments described are also analysed.
Four further cases of retroperitoneal liposarcoma are reported. Principal modes of revelation and diagnostic features are discussed, values of different complementary examinations evaluated, and prognostic factors and therapeutic elements of this serious affection outlined.
A case of an inoperable recurrent retroperitoneal liposarcoma, histologically diagnosed as being a mixed myxoid type and a round cell type, which was treated by continuous intra-arterial infusion chemotherapy, is reported. The authors applied this treatment method using adriamycin and 5-FU via the feeding arteries, i.e., the superior and the inferior mesenteric arteries. The tumor showed remarkable regression with no severe complications, even though general chemotherapy using adriamycin proved to be ineffective. This infusion method was thus evaluated as highly effective.
The author discusses liposarcoma of the ankle, a rare clinical entity, and four classifications of this disorder.
An 11-year-old girl noted a small mass on the left upper eyelid. The tumor was excised and diagnosed as round cell-type liposarcoma. In spite of intensive multimodal therapy, the tumor tended to recur, metastasizing to the central nervous system and soft tissues. The patient died of progressive disease three years after diagnosis. Features unique to this case include the ophthalmological primary site, the age at onset, the histological subtype and the mode of metastasis.
When confronted by a soft tissue neoplasm it is necessary to ask, before operation, whether it is malignant or benign. In this study of 6 cases of lipoma and 8 cases of liposarcoma of the limbs, the authors show that with the aid of computerised tomography the differential diagnosis can be made with certainty, based on densitometric evaluation.
To our knowledge, only seven cases of laryngeal liposarcoma have been reported in the English language literature. We add an eighth case and review the other seven cases. Our patient presented with a pedunculated mass arising from the left aryepiglottic fold and obstructing both the larynx and pharynx. The lesion has recurred locally three times in a period of four years. We discuss pathologic findings and management of this patient.
Liposarcomas are not frequently found in children or adolescents. An unusual localisation of this tumor was seen in a 14 year old girl. The prognosis of this disease is good in young patients. Surgical resection is the treatment of choice, chemo- and radiotherapy are additional therapeutic modalities.
We describe one case of retroperitoneal liposarcoma in newborn with few symptoms, evaluating the importance of the CT for his diagnosis.
Radical operation of a right perirenal myxoid liposarcoma is reported. Retroperitoneal sarcomas, in fact, show little response to antiblastic and radiation management. It is pointed out that angiographic diagnosis is an essential prelmiminary to correct surgical indication, particularly since the clinical picture may well be indistinct and poorly specific.
Tumors of adipose differentiation demonstrate considerable histologic variability as well as a wide variation in behavior patterns. A variety of clinical, gross, and microscopic features are useful in predicting behavior. Unfortunately, a number of different classification systems for liposarcoma with confusing nomenclature appear in the literature. This paper reviews general features affecting prognosis and presents a summary of the major classification systems. A subclassification of tumors into three grades (high, intermediate, and low) is suggested, based on potential for malignant behavior. Our system of grading may be used to guide the surgeon in the course of therapy. In light of the potential for confusion in identification and classification, good communication between surgeon and pathologist is essential to choice of appropriate therapy and ensuing chances for recurrence or survival.
Liposarcoma is a rare tumor in the larynx. A case of such lesion occurring in a 52 year old male patient is described. This is the second case to be reported in the world literature. The patient underwent hemilaryngectomy and later total laryngectomy for a recurrent tumor and is living and well six years after diagnosis.
A patient with abdominal liposarcoma is described, and the treatment of this in children extremely uncommon tumor is discussed. After complete surgical excision, local irradion with 5000-6000 rad should be considered only if no vital organs are irradiated. Because of the high tendency for local recurrence and for distant metastases of this tumor a primary polychemotherapy beginning immediately after surgical excision is proposed as in cases of other solid tumors in children for instance rhabdomyosarcoma or fibrosarcoma. 18 months after the surgical excision and after the beginning of polychemotherapy our patient is clinically well without demonstrable tumor growth.
Liposarcoma is a rare soft-tissue tumor. According to Enzinger, there are five subgoups. Histological criteria, the beginning, diagnostic and therapy of this tumor are represented. Results have been ascertained as follows, founded on eight cases of our own: 1. Adequate radical surgery and radiation therapy are needed in each case. 2. Recurrences are frequently, metastasition is rarely observed. 3. The prognosis is poor, if a recurrence appears within two years.
Metastasis of liposarcoma to the scalp occurred in a 50-year-old-man. Review of the literature disclosed no documented reports. Although cutaneous metastases from internal malignancies are of relative infrequent occurrence, such metastases may be limited to the scalp and a diagnosis can be established by a biopsy.
A large pedunculated myxoid liposarcoma of the cervical esophagus is presented. Because of its long pedicle, the presenting symptoms were primarily respiratory rather than digestive. The tumor lent itself to local excision rather than esophageal resection, given the absence of involvement of its pedicle and the resultant wide margin of excision. Review of the literature did not disclose a similar case.
A rare case of primary myxoid liposarcoma of the mesentery was observed and a detailed description of the clinical case and the operation performed is presented. In conclusion the clinical and diagnostic aspects of such tumours are analysed with emphasis on the major anatomical and pathological features.