Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “LEIOMYOSARCOMA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,045 records · Page 58Linked to original sources
PubMed2005

Leiomyosarcoma of the vulva: a case report.

BACKGROUND: Leiomyosarcoma of the vulva is a rare gynecologic malignancy, comprising approximately 1% of vulvar cancers. CASE: A 36-year-old woman was referred for a slowly growing painless vulvar mass that was initially thought to be a Bartholin's duct cyst but was cancerous upon biopsy. A modified radical vulvectomy was performed, and pathology revealed a grade 1 leiomyosarcoma. Thirteen months later, the tumor had not recurred. CONCLUSION: Vulvar cancer must be considered in patients with a suspected Bartholin duct cyst that demonstrates atypical features. A biopsy should be obtained if the mass appears firm or solid on palpation, is ulcerated or presents in a slightly different location from the usual area of the Bartholin gland.

Adult↗
PubMed2005

Laryngeal leiomyosarcoma.

Laryngeal leiomyosarcoma is rare. The authors report the case of a 48-year-old patient who presented with progressive hoarseness. This symptomatology was associated with a laryngeal tumour. Immunohistopathological study indicated a leiomyosarcoma. Acute dyspnoea resulted in an urgent tracheostomy, followed by total laryngectomy without neck dissection later. In the light of this observation and a literature review, histopathological characteristics, clinical aspects and therapeutic indications will be discussed for this localisation.

Dyspnea↗
PubMedDate not supplied

[Salvage surgery in the treatment of massive abdominal recurrence of uterine leiomyosarcoma. Clinical case].

Uterine leiomyosarcomas carry a dismail prognosis. Diagnosis is often an unexpected pathology discovery after hysterectomy for fibroma. Prognosis depends on the degree of locoregional extension and thus on early diagnosis. Extended surgery in case of relapse is sometimes the only possible approach for symptoms control and improvement of quality of life. A case of massive involvement of the abdomen by a relapsed uterine leiomyosarcoma treated by extreme surgery is here presented.

Abdominal Neoplasms↗
PubMed2005

Leiomyosarcoma of ovary--a case report.

Leiomyosarcomas are rare to arise in ovary and only 23 cases have been reported so far. They are considered to arise from components supporting the vascular elements in the hilar region. We report the case of a 75 year old lady, who was treated by resection of the tumour with hysterectomy and oophorectomy for ovarian leiomyosarcoma and followed up to six months.

Aged↗
PubMed2005

Leiomyosarcoma of the larynx: A case report.

Leiomyosarcoma of the larynx is an extremely rare neoplasm; only about 50 cases have been reported in the English-language literature. We report a new case of laryngeal leiomyosarcoma in a 65-year-old man. The metastatic work-up was negative, and the patient underwent total laryngectomy. He remained disease-free 12 months postoperatively.

Aged↗
PubMed2006

Leiomyosarcoma of uterus--a case report.

Leiomyosarcoma of uterus is a very rare malignant mesenchymal tumour of uterus. It may arise from the uterine myometrium de novo or may be transformed from a pre-existing benign leiomyoma. A 55-year-old female presenting with 20-22 weeks size of uterus and bleeding per vagina was clinically diagnosed as a case of leiomyoma uteri and cervical polyp, was subjected to abdominal hysterectomy. The tumour mass was later confirmed histologically as leiomyosarcoma of uterus presumed to be transformed from pre-existing leiomyoma uteri.

Female↗
PubMed2006

[Leiomyosarcoma of brachiocephalic vein: case report].

Primary leiomyosarcoma of venous origin is a rare but frequently lethal disease. Clinical symptoms can be different, often not much evident or absolutely absent. Preoperative diagnosis is difficult also with modern imaging and only pathological examination can identify this malignant tumor. Successful therapy requires early surgery but the long-term survival is poor. A case of leiomyosarcoma arising from veins has been presented.

Brachiocephalic Veins↗
PubMed2006

[Two cases of spermatic cord leiomyosarcoma].

A 72-year-old man and a 59-year-old man presented with painless hard swelling of left scrotal content. They underwent left high orchiectomy with clinical diagnosis of spermatic cord tumor. The pathological examination revealed leiomyosarcoma. The former had adjuvant radiation therapy locally. These are the 28th and 29th cases of spermatic cord leiomyosarcoma in Japan.

Aged↗
PubMed2007

Primary leiomyosarcoma of the mandible. A case report.

The aim of this article is to describe a case of leiomyosarcoma of the mandible with immunohistochemical analysis that was useful in making the final diagnosis. A 40-year-old woman was referred to the Stomatology Clinic of Sao Paulo Tatuape Hospital, for evaluation of a lesion on the left side of the mandible. This lesion presented a fast growth in the last 6 months. Intraoral examination showed a firm, fixed, red colored mass measuring, approximately 60-mm in diameter. No lymph nodes involvement was found. The radiographic examination showed a lytic lesion showed ill-demarcated radiolucent with facial and lingual cortical bone destruction. Microscopic examination of the mandibular lesion showed a neoplasm composed by interlacing fascicles of spindle-shaped cells. Most of the cells presented a blut-ended elongated shape. A marked cellular pleomorphism was observed, represented by cells with irregular shape and abundant eosinophilic cytoplasm. Nuclei were large, hyperchromatic, either vacuoled or cigar-shape. The cytoplasm of the cells stained red with Masson s trichrome stain. Neoplastic cells expressed vimentin, smooth-muscle actin, HHF-35 and desmin. These findings were consistent with the diagnosis of leiomyosarcoma.

Adult↗
PubMed1991

[Leiomyosarcoma of the duodenum].

The paper reports the case of a patient with leiomyosarcoma of the duodenum who underwent radical duodenocephalopancreatectomy and survived for 22 months after the operation. Following a review of the international literature on the topic, the diagnostic procedures and prognostic criteria of this uncommon tumour are discussed. In conclusion, leiomyosarcoma always presents considerable problems of diagnosis even with the aid of biopsy and only surgery can lead to recovery in a limited number of cases.

Duodenal Neoplasms↗
PubMed1991

[Leiomyosarcoma of the right ventricle. Report of a case and review of the literature].

Primary cardiac leiomyosarcoma is a very rare condition. Only 15 cases have been reported in the literature. We report the case of a 27 year old man admitted to hospital for chest pain in March 1985. Echocardiography showed a right ventricular tumour which was completely resected at surgery. The diagnosis of leiomyosarcoma was confirmed by histological examination. After 22 months follow-up, the patient was still alive despite pulmonary metastases. The diagnosis of cardiac tumour used to be made post-mortem but since the introduction of new methods of investigation, especially 2D echocardiography, the diagnosis can be made at an early stage and allows rapid surgical resection, the only means of obtaining the histological diagnosis and of completely curing benign tumours.

Adult↗
PubMedDate not supplied

A huge gastric leiomyosarcoma diagnosed preoperatively through diagnostic imaging.

The authors were able to diagnose a huge gastric leiomyosarcoma prior to surgery using various diagnostic imaging techniques. The patient was a 68-year-old woman who presented with a large gas-filled mass the size of a child's head in the center of her abdomen. Based on characteristic findings from a gastric barium study, CT, MRI, and angiography, the patient was diagnosed as having a gastric leiomyosarcoma displaying extramural growth. Upon operation an extramural tumor (20 x 19 x 12 cm) originating from the gastric antrum was confirmed.

Aged↗
PubMed1991

Abscessed leiomyosarcoma of the ileum.

A-49-year-old man was admitted because of a lower abdominal mass. During the five days prior to admission, he had noted fever and lower abdominal pain. Palpation of the abdomen revealed a tender mass, 10 cm in diameter, in the suprapubic region. An x-ray revealed an irregular collection of gas, 9 cm in diameter, in the pelvic cavity, which appeared as a mirror image when the patient was upright. Based on the physical finding and the results of a barium enema, abdominal CT, MRI, and small intestine imaging, a diagnosis of leiomyosarcoma of the ileum was made. Excision of the tumor and part of the small intestine was performed. A saccular tumor, 11 x 6 x 5 cm, was found 1.0 m from the cecum and growing out of the wall of the ileum. A large amount of pus was found inside the cavity. The pathological diagnosis was leiomyosarcoma.

Abscess↗
PubMed1991

Myxoid leiomyosarcoma of the stomach: a case report.

A case of myxoid leiomyosarcoma of the stomach which developed in a 53-year-old man is reported. The tumor was localized mainly in the greater omentum and was directly connected to the muscle layer of the stomach. No direct invasion to adjacent organs, peritoneal disseminations or distant metastases were noted. Histologically, the tumor prominently comprised a myxomatous lesion with a cellular area portion. The tumor cells had a bipolar or multipolar shape with oval or elongated nuclei, and were scattered in the myxoid stroma which was rich in hyaluronic acid. The cellular area showed a fascicular tumor cell arrangement and also contained pleomorphic tumor cells with abundant mitoses. Immunohistochemically, the tumor cells were positive to vimentin and weakly positive to desmin. Ultrastructurally, pinocytotic vesicles and cytoplasmic microfilaments with focal densities were found in the tumor cells. It is considered important to differentiate between the diagnosis of myxoid leiomyosarcoma and that of any other myxoid malignant tumor.

Desmin↗
PubMed1991

Pancreatic leiomyosarcoma. A case report.

The pancreas is an unusual site for leiomyosarcoma. Only 12 such cases have previously been reported. A case of pancreatic leiomyosarcoma in a 68-year-old man is presented and the diagnostic dilemma and management of such a tumour are discussed.

Aged↗
PubMed1991

Leiomyosarcoma of large and small veins: clinical findings and results of treatment in six patients.

Vascular leiomyosarcomas are rare malignant tumours originating from the media of the vessel wall. Six patients (five women and one man, aged 44-66 years) have been treated for a vascular leiomyosarcoma located in the inferior vena cava (three patients), the suprarenal, the external iliac and an antecubital vein. In four patients, the tumour was large and extended beyond the vessel wall giving rise to a retroperitoneal mass. In two patients the tumour was confined to the inner wall of respectively a large and small vein, occluding the lumen; the former was in the inferior vena cava and the latter in an antecubital vein. Block resection was performed in all patients. The tumours showed mitotic indices ranging from 6-32 mitoses/10 high power fields. The five patients with retroperitoneal tumours received additional radiotherapy varying from 50.00-70.00 Gy, on the basis of either macroscopic residual tumour or indefinite radicality. One of these five patients developed distant metastases within 2.5 years without local recurrence, the other four had no evidence of recurrence at follow-up, 3-7 years (mean 4.2 years) after surgery. The results illustrate the role of adjuvant radiotherapy in the control of local recurrence, when resection in this type of tumour proves to be either non-radical or totally radical.

Adult↗