Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “HAND DERMATOSES”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,045 records · Page 58Linked to original sources
PubMed1980

Antichlamydial antibodies in chronic palmoplantar pustulosis.

Serum antichlamydial antibodies were determined with an immunofluorescence method in 40 patients affected by palmoplantar pustulosis (PPP). Antibody titre greater than or equal to 16 was found in 53% of the cases, the titre being greater than or equal to 64 in 38% of the patients. By comparison, a titre of greater than or equal to 64 was found in 13% out of 55 psoriatics, in 12% out of 41 eczema and urticaria patients, and in 3% out of 37 healthy controls. The difference between the results from the PPP patients and that of the healthy controls was statistically significant (p < 0.01). In only 8 of the 40 PPP patients was any additional evidence found of a previous venereal infection. The possibility that PPP may represent an abnormal reaction to infectious agents, e.g. Chlamydia, is discussed.

Adult↗
PubMed1981

Increased prevalence of antithyroid antibodies and thyroid diseases in pustulosis palmoplantaris.

A statistically significant increased prevalence of antithyroid antibodies was found by an indirect immunofluorescence technique in 37 patients with pustulosis palmoplantaris, as compared with an approximatley age- and sex-matched group of healthy controls. A history of thyroid disease was also more frequent in patients with PPP than in the population at large. The increased risk of thyroid dysfunction should be kept in mind in the long-term care of PPP cases. The prevalence of non-cutaneous autoantibodies was not increased in psoriatic subjects. The results accord with the concept that PPP and psoriasis may be separate entities.

Adult↗
PubMed1982

The treatment of onychomycosis with miconazole tincture.

Treatment of onychomycosis is usually unsatisfactory. A small clinical trial using a solution of miconazole (Daktarin; Janssen) in alcohol was undertaken to assess its potential in this difficult condition. Ten unselected patients completed the 32-week trial and the results, irrespective of whether the infecting organism was fungal or monilial, are recorded. A much larger and controlled trial is essential before firm conclusions may be drawn, but the results, particularly in Candida infections, are encouraging.

Administration, Topical↗
PubMed1984

Primary and secondary sites of occupational contact dermatitis.

Patterns of distribution of allergic contact dermatitis follow a certain order in time. The disease starts at a given site, most often as a unilateral acrodermatitis and, should it become chronic, spreads locally. The subsequent pattern of distribution varies depending on the primary site and the type--occupational or otherwise--of the disease. In this study data collected two decades ago are confronted with the more recent ones relating to 1055 cases of occupational allergic contact dermatitis. Examination of this material brought to light no essential difference between the older and more recent patterns of distribution of secondary sites. The incidence, however, of certain multiple localizations and of the primary or secondary involvement of the face has diminished.

Dermatitis, Atopic↗
PubMed1983

On the role of proteinases from Candida albicans in the pathogenesis of acronecrosis.

Evidence is presented for the involvement of proteinases from Candida albicans in the pathogenesis of acronecrosis that occurred in a young woman and which coincided with Candida sepsis. Secretory acid Candida proteinase by immunofluorescence was traced in the obstructed blood vessels of necrotic skin that was infested with yeast. The specificity of immunofluorescence was proven by exclusion of cross reactivity with pepsin, cathepsin-D, acid erythrocyte proteinase and porcine renin. The possible molecular mechanisms of interference of fungal proteinases are discussed with respect to the renin-angiotensin system and blood coagulation.

Adult↗
PubMed1984

Immunohistological studies on tonsils with recurrent tonsillitis and focus-tonsil with pustulosis palmaris et plantaris.

By use of monoclonal antibodies and anti-immunoglobulin antibodies, the distributions of 15 adult tonsils with recurrent inflammation and palmoplantar pustulosis as focus-tonsil were investigated. The avidin-biotin-peroxidase complex (ABC) method was utilized throughout the experiment. Monoclonal antibodies of the Leu and OKT series revealed the location of T and B cell subsets characteristic in the tonsils with chronic inflammation and the focus tonsils with pustulosis palmaris et plantaris (PPP). In vitro sensitization of tonsil tissues was performed with crude antigen from tonsillar epithelium. Tonsil tissues with PPP demonstrated a significant increase in S-IgD-bearing lymphocytes and esterase-positive cells in the mantle zones of follicles, although the tissues of recurrent tonsillitis showed no such effects. It was speculated that tonsils with focal infections are usually standby for the production of antibodies against tonsillar epithelial antigens.

Adult↗
PubMed1980

[An aetiological study on pustulosis palmaris et plantaris due to tonsillar focal infection (author's transl)].

In clarification of the cause of Pustulosis palmaris et plantaris caused by tonsillar infection 19 patients with this condition and undergoing tonsillectomy were studied. IgE levels in the tonsils and blood serum were estimated both before and after tonsillectomy including various other laboratory tests. These results and the therapeutic effects of the tonsillectomy were analysed. 42 patients with tonsillitis undergoing tonsillectomy were used as controls. Lowered serum complement (C3) titres and decrease in neutrophil counts and serum IgG levels were observed in those patients whose cutaneous lesions were either completely or greatly improved following tonsillectomy. As neither the IgE levels in the tonsils nor in the serum were altered after tonsillectomy, the possibility of IgE mediated allergic type I reaction, as previously proposed by the present authors, was ruled out, and the aetiology was assessed to be an infectious allergy based on the Arthus reaction classified in the type III reaction.

Antistreptolysin↗