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[4 anthroposcopic markers in the Northern Greece population: hand folding, arm folding, tongue rolling and tongue folding].

Four anthroposcopic traits, namely hand clasping, arm folding, tongue rolling and tongue curling have been studied in a total of 7763 individuals from Thessaloniki and its surroundings, representing a sample of the population of Northern Greece. The statistical analysis of the data indicates significant sex differences only concerning tongue rolling. The frequencies obtained for the four traits under study are compared with data from the literature.

Ethnicity↗

Investigation on the distribution of genetic polymorphisms in Greece. 3. Red cell enzyme polymorphisms and genetic distances G.

112 Greeks living in W. Germany and coming from various parts of Greece and 280 individuals from the Isle of Alonissos (northern Aegean Sea) have been typed for seven polymorphic red cell enzymes, namely red cell acid phosphatase (aP), phosphoglucomutase (PGM1) adenylate kinase (AK), 6-phosphogluconate dehydrogenase (6-PGD), esterase D (EsD), glutamic-pyruvic transaminase (GPT), and glyoxylase I (GLO). The gene frequencies obtained in these two samples are compared with the hitherto reported corresponding data from other Greek populations. Finally genetic distances (basing on six polymorphic serum protein and red cell enzyme systems) have been computed for seven Greek population samples. The results of these distance measurements are discussed.

Acid Phosphatase↗

[Thermal springs of Kavassila/N. Ioannina/, Greece--research study].

The thermometallic springs of Kavassila, district Ioannina, are situated at a height of 410 m in a mild intermediate microclimate. They spring forth in two groups of springs near Sarantaporos river into which they pour without proper exploitation. Examinations of the water of the springs such as microbiological, microfloric blue algae and physico-chemicals have produced mainly: supply 400 m3/h, temperature 32 degrees C, electrical conductivity 1850 mS, colourless, taste of drinkable water, no emulsion, pH 7,60-8,20, sulfuric content 175,7 mg/l, strong odour of hydrogen sulphide, radon content 13-14 MACHE. Based on the above, the springs are to be characterised as hypothermic, hydrogen suplphide and sodium chloride containing mineral water, which is very suitable for drinking and bath therapy according to the principles of hydrotherapeutics: Water bath therapy and mud bath for the following diseases: skin diseases, rheumatoarthritic, chronic gynaecological, as well as vascular diseases. Inhalation therapy for troubles such as chronic troubles of the respiratory diseases, asthma, emphysema and laryngo-faryngeal pathological condition in both smokers and non-smokers. Drinking therapy for problems arising from the gastrointestinal tract, liver, bile ducts and kidneys. Similar springs in Greece, compared and mentioned are: Thermopylae, Kaiafa, Kyllini and abroad: Apenta-Springs Hungary and Piatigorsk Russia. For the correct exploitation of the thermomineral waters in Kavassila, the build-up of a modern curative hydrotherapeutic centre is proposed, due to the quality of the springs, as well as it's good and healthpromoting climate.

Balneology↗

Delta antigen positive chronic liver disease in Greece: clinical aspects and natural course.

Chronic delta infection occurs in Greece in about 10 to 15% of HBsAg+ subjects, being largely unrelated to parenteral transmission and/or to drug addiction. The observed cases exhibited histological changes ranging from chronic persistent hepatitis to chronic active hepatitis, cirrhosis, and even hepatocellular carcinoma on cirrhosis. The male/female ratio of patients with delta Ag + CLD was 3.8:1 and their mean age 40 years. They were younger compared to delta Ag-/HBsAg+ CLD and they presented with a wide spectrum of symptoms and signs. About 25% of the patients were oligosymptomatic or asymptomatic and about 40% manifested their disease as an episode of acute hepatitis with protracted or relapsing course followed by chronicity. Biochemical changes appeared to be more severe than in delta Ag-/HBsAg + CLD. The natural history was frequently characterised by a progressive course, terminating, in about 15 years, to death from cirrhosis and liver failure, although remissions occasionally occurred. HCC also developed but probably less frequently than in HBsAg positive, delta Ag negative CLD. Whether the natural course of delta Ag+ CLD can be modified by any form of treatment remains to be proved.

Adult↗

Investigations on the distribution of genetic polymorphisms in Greece. 2. Serum protein polymorphisms.

113 Greeks living in W. Germany and coming from various parts of Greece and 281 individuals from the Isle of Alonissos (northern Aegean Sea) have been typed for six serum protein polymorphisms, namely haptoglobin, group specific component (Gc), C 3, transferrin subtypes, Gm (1, 2, 3, 5, 13), and Inv (1). The gene frequencies obtained in these two samples are compared with the up to now reported data from other Greek populations. They show a marked genetic heterogeneity with respect to these polymorphisms.

Blood Proteins↗

Some epidemiologic studies of HBSAg in Greece.

In an epidemiologic study in 17 villages from different areas of Greece, 2898 persons were examined in order to find possible relations between HBSAg prevalence, altitude and endemic goitre morbidity. A lower prevalence with a significant difference was found in areas with a high altitude as compared with those with a low one, in endemic goitre than non-endemic areas, and in low altitude endemic than in low altitude non-endemic areas. Goitrous subjects had a lower HBSAg prevalence than non-goitrous subjects, but the difference was of borderline significance. The results can probably be explained by the presence of an environmental factor associated with altitude acting together with a host factor predisposing to endemic goitre and favouring the immunity to HBV infection.

Altitude↗

[Evaluations of respiratory functional parameters in sponge fishers from the island of Kalimnos (Greece)].

We had intended to study functional respiratory patterns of a sponge-divers group from the Island of Kalymnos (Greece). Such a group constitutes a very homogeneous sample for dietary habits and underwater activity, handed down from father to son. Some of these sponge-divers dives holding his breath; others use "narghilè", a special apparatus consisting in a nosepiece connected to an air compressor placed in the boat. As their activity is continuative and prolonged for several months in the years with repeated dives from dawn to dusk, and because air output of narghilè is nearly constant, it is possible to deduce that in these subjects functional respiratory modifications are occurred. After evaluated three groups (skindivers, narghilè-divers and control-group) we didn't notice any particular change of static and dynamic pulmonary volumes. Only Expiratory Reserve Volume is higher in spite to Knudson's values; this is probably due to psychological and emotional factors.

Diving↗

Mortality among institutionalised people with learning disabilities in Greece: a 30-year survey at the Leros PIKPA asylum.

The life expectancy of institutionalised people with learning disabilities is shorter than that of the general population. Data on population dynamics in institutions for such people are vital for planning purposes. Mortality can be considered a crude measure of quality of health care. Mortality data on the 914 admissions to the Leros PIKPA asylum for children and young adults with learning disabilities and associated problems in the years 1961-91 were reviewed. The overall crude mortality rate was 59.2 deaths per 1000 person-years. Twenty-two per cent of the deaths occurred within a year after admission. Age-specific mortality rates were particularly high for those aged one to four years, and declined thereafter. Male residents had lower mortality than female residents in almost all of the age groups. Compared with sex- and age-specific mortality data for the general population of Greece, the observed rates were 20-150 times higher but still comparable to those reported for people with more severe learning disabilities in institutions in other countries. Lifetable analysis by length of stay showed that male residents had a statistically significant higher probability of survival than female residents, which could not be attributed to age-related differential mortality. Culture-specific differential admission criteria may account for the observed sex difference.

Adolescent↗

Whole blood lead concentration and erythrocyte delta-aminolevulinic acid dehydratase (ALAD) activity in selected canine populations in Greece.

In a total number of 275 dogs of various ages, sex and breed, blood lead concentrations (BLC) and erythrocyte ALAD activity were measured. Sixty-six of the dogs were living in lead mining areas (Group A), 157 in urban areas (Group B) and 52 in rural areas (Group C) of Greece. Mean BLC differed significantly (P < 0.05) between locations and were 326,97 and 68 micrograms/L, respectively. Mean ALAD activity was significantly different (P < 0.05) only between Groups A and B as between groups A and C. A significant (P < 0.05) negative correlation existed between BLC and ALAD activity. A normal range of erythrocyte ALAD activity of 807-992 mumol/PBG/LRBC/h was established for dogs. None of the 33 Group A dogs and 2 of the Group B dogs that had a BLC of 350 micrograms/L presented clinical signs indicating acute or chronic lead intoxication. No erythrocyte basophilic stippling or large number of nucleated red blood cells were seen in the 30 dogs of Group A with BLC > 350 micrograms/L.

Animals↗

Incidence of subclinical lead (Pb) exposure in cattle of an industrial area in Greece.

The incidence of subclinical lead (Pb) poisoning was investigated in the cattle population of an industrial area in northern Greece. The cattle were divided into two groups with respect to their alleged exposure to Pb, which was assayed by determining whole blood and hair Pb concentration and erythrocyte delta-aminolevulinic acid dehydratase (ALA-D) activity. The cows which were located closer to potential contamination sources were found to have higher (P < 0.05) blood and hair Pb content, whereas no significant differences were noted in ALA-D activity. Hair Pb increased significantly (P < 0.05) with age, an observation which should lead to further, more extensive research, in order to evaluate the possibility of using hair as indicator of chronic Pb intake.

Animal Feed↗

Current profile of active leprosy in Greece; a five-year retrospective study (1988-1992).

The epidemiological characteristics of newly diagnosed, active leprosy cases (incidence, N = 16 Greeks and 4 expatriates) and relapsed cases (recurrences, N = 25, all Greeks) were studied. Most of the cases were multibacillary, over 50% being lepromatous. The relapses were analyzed by sex, disease duration and residence (rural or urban). Most of the newly diagnosed cases presented with nonreactional skin lesions (70%). The relapses were self-reported and detected mainly because of type 2 leprosy reactions (56%). The main source of the infection for new cases was members of their former extended family. The statistical trend of leprosy in Greece is a continuing decline in a country which already has a very low endemicity.

Adolescent↗

[Healthy meningococcal carriers in 1973 in Greece. Sensitivity of the isolated strains to minocycline, rifampicin and sulphadiazine (author's transl)].

The frequency of healthy carriers of meningococci in Greece in 1973 has been studied by examining 1105 nasopharyngeal swabs from 731 recruits, during the four recruitment periods of this year. The frequency of healthy carriers among inductees within 24 hours from the arrival in the Camp was 38.9%. After a stay of 35 to 40 days in the training Camp the frequency of healthy carriers rose to 66.4%. Among all the soldiers examined, 24.5% were carriers of meningococci of group B, 13.2% of non-typable strains, 8.1% of autoagglutinable strains, 4.1% of meningococci of group A, 3.7% of meningococci of group C and smaller percentages of strains of groups X, Y, Z and of cross-agglutinating strains. The prevalence of carriers of meningococci of groups A and C and of autoagglutinable strains was higher among recruits who have been in the Camp for 35 to 40 days. The prevalence of carriers of the other serogroups was about the same among the inductees and the other recruits. No significant differences were found in the frequency of carriers of each serogroup among soldiers on their arrival, who were permanent residents of urban or rural areas of various parts of the country. No significant seasonal variation was noted in the frequency of carriers of each serogroup. Frequent changes of the group of meningococci harboured were noted among 374 recruits examined upon their arrival, as well as after 35 to 40 days of residence in the training Camp. Among 534 strains of meningococci examined none was resistant to either minocycline or rifampicin. Among 226 strains isolated from inductees, 44.7% were resistant to 1 mug/ml of sulphadiazine, while among 235 strains isolated from recruits after they have been in the Camp for 35 to 40 days, 57.9% were resistant to that sulphonamide.

Carrier State↗

Diet and coronary heart disease: a case-control study in Athens, Greece.

We conducted a case-control study in Athens, Greece, between January 1990 and April 1991 to examine the association between diet and coronary heart disease. The case series comprised 329 patients with electrocardiographically confirmed first coronary infarct or a first positive coronary arteriogram, or both, who were admitted to a major teaching hospital during a 16-month period. Controls were 570 patients admitted to the same hospital for minor conditions believed to be unrelated to nutrition. Total energy intake was inversely associated with coronary heart disease risk, a quintile energy increase corresponding to a relative risk of 0.96. After controlling for total energy intake, dietary fat was positively related to coronary heart disease, and total carbohydrates were negatively related to coronary heart disease, the nutrient-specific relative risks for a quintile increase being 1.19 (95% confidence interval = 0.96-1.48) and 0.81 (95% confidence interval = 0.67-0.97), respectively. Major fat components (saturated, monounsaturated, and polyunsaturated fat) did not appear to have differential risk implications for coronary heart disease; however, cooking with margarine was associated with an increased relative risk (1.87; 95% confidence interval = 0.82-4.28). Dietary proteins, cholesterol, and vitamin C were not associated with coronary heart disease.

Aged↗

The incidence of gallstones in Greece; an autopsy study.

In the fifty-year period, from 1925 to 1974, 6596 autopsies were performed at three departments of Pathology in Athens. The incidence of gallstones was 5.97% in the total material. The incidence in females was 8.86% and in males 4.52%, with a ratio 2:1. An increase of the incidence has been noticed since 1925. Under the presented data Greece could be included among the countries with an intermediate frequency of gallstones, but with a tendency to follow the Western countries pattern. The significance of the Greek standard of living and the dietary surveys on the gallstone formation, are briefly discussed.

Adolescent↗

DYS19, D12S67, and D1S80 polymorphisms in population samples from southern Italy and Greece.

Genotype and allele frequencies of the DYS19, D12S67, and D1S80 highly polymorphic loci were determined in population samples from southern Italy (103 subjects) and Greece (84 subjects) using the amplified fragment length polymorphism (AFLP) technique (polymerase chain reaction followed by native PAGE and silver staining). Five, eleven, and eighteen alleles were found at the DYS19, D12S67, and D1S80 loci, respectively. PIC values ranged from 0.55 (DYS19 locus in Italians) to 0.79 (D12S67 locus in Italians). The distribution of D12S67 and D1S80 genotypes conformed to Hardy-Weinberg equilibrium, as confirmed by three statistics. Heterogeneity G tests, carried out on allele frequency distributions, showed a significant difference between the samples at the DYS19 locus, whereas no difference was found with regard to the other polymorphisms. Using data from the literature, we widened the comparison to other European groups analyzed for the same markers. All the polymorphisms were found to distinguish between populations of the same main ethnic group. In particular, D1S80 allele frequencies distinguished the Finns from other European groups (Spanish, German, Italian, and Greek samples). The reduced assay time, the high polymorphism level, and the ability to distinguish between populations indicate that these markers have potential value in population genetic studies.

Alleles↗

Prevalence of obesity in Greece.

The purpose of the present study is the presentation of the available literature on obesity in Greece. The heterogeneity of design, small sample size and limited number of studies conducted, complicates the delineation of definite trends. Nevertheless, the existing literature appears to point at a high prevalence of obesity among Greek children. Childhood obesity, may partly be accounted for by the over-protection and forced feeding by Greek parents. With regard to the incidence of obesity among Greek adolescents, studies have yielded controversial results. On the other hand, the existing evidence appears to indicate a high prevalence of obesity among Greek adults and the elderly, particularly those above 30 years of age. In contrast to the females, males appear to be characterised by central obesity. These observations highlight a need for primary prevention measures.

Adolescent↗