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[Alterations in Fallopian tube biopsies caused by pregnancy (author's transl)].

The clinical significance of decidual changes and inflammation in Fallopian tubes of women undergoing sterilization shortly after the delivery was assessed microscopically in 133 resected specimens. Thirteen excision specimens obtained from non pregnant patients served as controls. Foci of ectopic decidua in the mucosa were found in 14.3% of cases in the first group, whereas none was noted in the control group. An inflammatory reaction consisting of edema, hyperemia, and lymphocytic, histiocytic and occasional granulocytic infiltration was noted in 67.6% of patients ligated after delivery. No significant inflammatory reaction was demonstrated in specimens of the control group. In the post partum group the clinical findings and the gross examination of the tubes at the time of operation did not suggest any inflammatory changes. The microscopic changes observed therefore do not warrant the diagnosis of a salpingitis and are to be considered as a physiological response during pregnancy.

Adult↗

Mature cystic teratoma of the fallopian tube associated with an ectopic pregnancy.

We describe the occurrence of a mature cystic teratoma of the fallopian tube discovered at laparoscopy for an ectopic pregnancy. Only five previous reports of this concurrence have been found in the medical literature. We review the reported cases of tubal teratoma and summarize all cases found with an ectopic tubal pregnancy.

Adult↗

Primary choriocarcinoma of the fallopian tube: report of a case.

A case of the relatively rare condition of a choriocarcinoma in the fallopian tube is presented. The patient apparently recovered completely and quantitative beta hCG assay demonstrated negative results after TAHBSO and adjuvant chemotherapy. This brings the total cases reported to 77.

Adult↗

Immunohistochemical analysis of estrogen and progesterone receptors in fallopian tubes during ectopic pregnancy.

OBJECTIVE: To study decidualization, estrogen receptor (ER), and progesterone receptor (PR) expression in fallopian tubes containing an ectopic pregnancy (EP). DESIGN: Assessment of decidual reaction by light microscopy, staining of ER and PR in epithelium and stroma by immunohistochemical methods. SETTING: Academic hospital. PATIENTS: Twelve women with an ampullary located EP. INTERVENTION: A partial or complete tubal resection. RESULTS: Only minimal decidualization was observed in five tubes. Estrogen receptor expression was noted in glandular cells in seven tubes. No correlation was found between decidualization and ER staining. No PR expression was seen in glandular epithelium or in stroma. CONCLUSIONS: It is postulated that absence of PR is correlated to poor decidualization and to failure of treatment of EP with antiprogestins (RU486).

Decidua↗

A solitary diverticulum of the fallopian tube.

A rare case is described in which a diverticulum of the middle portion of the right Fallopian tube was demonstrated by hysterosalpingography. The patient aged 26 years, had a history of a ruptured left mid-tubal pregnancy 8 years previously and was suffering from infertility. The radiographic appearance of the lesion is characteristic, the aetiology is obscure and treatment should be conservative.

Adult↗

[Primary cancer of the fallopian tube. A case revealed by pelvic peritonitis].

We report the case of a primary carcinoma of the fallopian tube in which the diagnosis was done through laparoscopy for pelvic peritonitis. The pathologic diagnosis was possible with tubal sampling at the same time. The treatment associated radical surgery and radiotherapy. This rare kind of tumor is exceptionally diagnosed this way.

Adenocarcinoma, Papillary↗

Outpatient falloposcopy: intra-luminal imaging of the fallopian tube by trans-uterine fibre-optic endoscopy as an outpatient procedure.

OBJECTIVE: To develop trans-uterine falloposcopy using the linear eversion technique in outpatients. DESIGN: A prospective, descriptive study of the introduction and application of this new technique. SETTING: A tertiary referral University Research Clinic independent of operating theatres and inpatient admission. SUBJECTS: Twenty-one infertile women with previous evidence of fallopian tube disease. MAIN OUTCOME MEASURES: Rate of successful tubal cannulation and procedure completion, tubal section visualized, condition of the tubal epithelium, subsequent treatment plan. RESULTS: A bilateral examination was attempted in 19/21 patients and completed in 18. Two early falloposcopies with inadequate analgesia were aborted due to pain after only one tube had been examined without an attempt to identify or cannulate the contralateral tubal ostium. In one patient, neither ostium was identified or cannulated. After ostial localization, 37/37 tubes were cannulated. If the ostium was not localized but 'blind' cannulation attempted, 1/3 were cannulated successfully. Epithelium characteristic of the ampulla was seen in 31/38 (82%) tubes, and of the proximal tube only in 3/38 (8%). Successful bilateral assessment noted complete bilateral proximal obstruction in 2/18 patients, non-obstructive bilateral endotubal damage in 7/18, unilateral damage in 3/18 and bilateral healthy tubes in 6/18. Unilateral examination in two patients found minimal evidence of damage in one and severe intra-tubal adhesions in the other. After falloposcopy, 11/21 patients elected for IVF, 9/21 tubal surgery and 1/21 for IVF whilst awaiting surgery. CONCLUSION: Falloposcopy is a technique which can be performed in an outpatient clinic. It is well tolerated, and high rates of luminal cannulation and visualization are possible. Atraumatic access to the tube and visualization of its lumen offer exciting opportunities for diagnosis and treatment of tubal conditions.

Ambulatory Care↗

Transvaginal ultrasonographic study of the fallopian tube.

The use of transabdominal/transvesical sonography in gynecologic diagnosis is limited by the physical properties of the transducers used as well as the lack of sufficient acoustic interfaces. Therefore, delicate tubal structures cannot be visualized adequately. Transvaginal application of a 6.5-MHz transducer probe (with a 10-mm crystal) enables the effective use of higher frequencies, enhancing resolution. This higher resolution improves picture quality and increases potential diagnostic power in evaluating the female pelvis in general and the fallopian tube in particular. This report presents the sonographic picture of the normal and pathologic tube. Tubal pathology should be described in terms of the tubal cavity, walls, and content, as well as location and mobility. The more frequently encountered clinical entities, such as the fluid-filled tube, tubo-ovarian inflammatory processes, and tubal gestation are discussed.

Fallopian Tube Diseases↗

Atypical epithelial proliferations in the fallopian tube.

Between the years 1950 and 1979, thirty-nine diagnoses of "atypical epithelial proliferation in the fallopian tube" were made in the Gynecologic Pathology Laboratory at The Johns Hopkins Hospital. In this discussion, the criteria for histopathologic diagnosis of such alterations are described. This series demonstrated an association of the tubal proliferations with malignancy in the upper genital canal and exogenous or endogenous estrogen stimulation. However, progression of these proliferative conditions to invasive tubal cancer was not documented.

Epithelium↗

Term pregnancy after fallopian tube transposition.

A 23-year-old woman suffered from primary sterility because of congenital malformation of the uterus and tubes. There was a left unicornuate uterus. The left ovary and the isthmic and ampullary parts of the right tube were missing. Microsurgical transposition of the left tube was performed successfully. Our technique may encourage microsurgeons to use transposition of fallopian tube in cases in which only one tube and one ovary on contralateral sides are available.

Adult↗

Recanalization of obstructed fallopian tube by selective salpingography and transvaginal bougie dilatation: outcome and cost analysis.

OBJECTIVE: To investigate effectiveness and cost of transcervical salpingography and recanalization in the management of infertility caused by tubal occlusion. DESIGN: Retrospective analysis of patients investigated with transcervical selective salpingography and, in some instances, treated by transcervical recanalization. SETTING: Four hundred patients with hysterosalpingography diagnosis of obstructed fallopian tubes (clinical environment) are investigated. A repeat hysterosalpingogram after administration of a prostaglandin antagonist demonstrated patency of the tubes in 82 patients and selective transcervical salpingography demonstrated patency in an additional 131 patients. INTERVENTION: Transcervical tubal recanalization. Of the remaining 187 patients, recanalization by transcervical technique was successful in 145 patients. The underlying etiology for tubal obstruction was salpingitis isthmica nodosa in 62, salpingitis and perisalpingitis in 71, endometriosis in 8, failed surgical anastomosis in 43, and undeterminate cause in 3 patients. Pregnancy was attained in 24 patients, there were 10 minor and 1 major complication. OUTCOME MEASURE: Attained and maintained patency of tubes, pregnancy, attendant complications. CONCLUSION: A pregnancy rate of 12.8% was attained after transcervical recanalization of obstructed tubes. An attendant increased rate of pregnancy in patients proven patent after selective salpingography, valuable detailed information about proximal and distal tubes after recanalization of the obstructed proximal tube segment, the low rate of complications, and low cost are factors recommending the use of this technique. Moreover, tubal surgery or IVF treatment are not influenced adversely by prior transcervical tubal recanalization and remain an option for patients who failed to attain pregnancy.

Adult↗

[Second look laparoscopy after fallopian tube perforation with the tubal endoscope].

In recent years, falloposcopic, visualization of the tubal lumen has become a topic of great interest. The development of a linear everting catheter system (Imagyn Medical Inc., Laguna Niguel, Calif., USA) allows cannulation of the fallopian tubes without exerting shear forces upon the tubal epithelium. We report the findings of a second-look laparoscopy after accidental tubal perforation at falloposcopy. Second-look laparoscopy was performed in a patient 6 months after tubal perforation with the falloposcope and no adhesions or signs of inflammation could be detected. On chromopertubation, no tubal fistula was found to be present. Two months after treatment, the patient got pregnant spontaneously. Pregnancy and delivery were without any complications. We conclude that technique of falloposcopy provides a safe access to the endotubal lumen. Even a perforation created by the microendoscope does not appear to be associated with any long-term complications.

Adult↗

[Primary metastasizing fallopian tube carcinoma. Case report and overview of current therapy].

Case report a primary metastasizing carcinoma of the fallopian tube with radical operation and 4 cycles of antineoplastic chemotherapy (cisplatin and treosulfan). Tumor markers decreased to normal level following primary treatment and the first chemotherapy cycle. After six months we did and immunoscintigraphy and second-look-laparotomy including the Regaj-procedure. There was a histological complete remission. Additionally we give a review about cytostatic treatment of this cancer the last then years. Radical operation combined with adjuvant chemotherapy is said to be successful.

Adenocarcinoma↗

Spontaneous contractile pattern of isolated circular and longitudinal muscle layers from the ampullae of normal and damaged fallopian tubes.

Ampullary biopsies were obtained from twenty-three normal fertile women and from eleven women with hydrosalpinges. The contractile activity of 4-mm muscle strips was studied isometrically in organ bath. Both normal circular and longitudinal muscle strips contracted with similar frequency, duration and amplitude. Circular and longitudinal muscle strips from hydrosalpinges contracted with a lower frequency and a longer duration and the amplitude of contractions was higher than normal. The difference in frequency and duration was statistically significant. The possible explanations for these differences in rhythmicity between normal and diseased fallopian tubes are presented and the prognostic relevance discussed.

Adult↗