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[Short- and long-term immune status in people after radiation injury as a result of the accident at the Chernobyl Nuclear Power Station].

Humoral and cellular factors of the immune system of 133 subjects injured in the Chernobyl accident were studied during first 1.5-2 months after radiation, 5-17 months and 3 years after they suffered acute radiation sickness (I-IV degree). Significant disorders in the immune system correlating with the severity of the disease were recorded. In late terms certain shifts persisted in the immune status of subjects who had suffered acute radiation sickness, II and III degree.

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[Psychological aftereffects of the disaster at the Chernobyl NPS].

Available are the data on the trend in psychoneurological syndromes demonstrable in all the periods of developing acute radiation disease in the victims of the disaster at the Chernobyl nuclear power station. It is shown that the risk of small-dose ionizing radiation may lead to psychological dysadaptation. Psychogenias are outlined as far as their triggering factors and manifestations in members of the emergency teams are concerned.

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[Content of blood lipids and characteristics of dyslipoproteinemias in people exposed to radiation during the accident at the Chernobyl nuclear power station].

Lipid and lipoprotein spectrum of the blood plasma was investigated and phenotyping of hyperlipoproteinaemias was carried out in men exposed to ionizing radiation and suffered from acute radiation illness as a result of the Chernobyl accident. An increase of the total cholesterol triglycerides and content frequency of atherogenic types of hyperlipoproteinaemias in comparison with average levels of population both a year and 3 years after irradiation was observed. No essential differences were found between the obtained indices 1 and 3 years after irradiation which testified to the stability of the revealed disturbances.

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Changes in the iodine content of vegetables following the Chernobyl accident.

In the early phenophases and at maturity the vegetables grown in the goitrogenic area have a lower iodine concentration than in non-goitrogenic areas. Within the same area, the amount of iodine is higher in young than in old vegetables and, in some species, it is higher in the young vegetables of the goitrogenic area than in the nature vegetables of the non-goitrogenic ones. Following the accident at the Chernobyl Nuclear Power Plant in April 1986, the iodine metabolism in plants was disorganized.

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[Dosage of irradiation of the population in the Bryansk region with plutonium deposited in the soil after the Chernobyl AES accident].

Proceeding from the data on 238Pu, 239Pu, 240Pu concentrations in the soil in different areas of the Bryansk Region, exposed to radioactive contamination after the Chernobyl accident, radiation dose exposures of residents as well as agricultural workers were assessed. Criteria of the ecological and radiation-hygienic standardization were used for calculation of values of dose factors, binding the alimentary and inhalation components of an irradiation dose with characteristics of Pu deposition in the soil. Inhalation of soil particles accounted for approximately 90% of a total radiation dose of the "soil" Pu component, and the alimentary component-for approximately 10% (of this, 99% were attributed to plant products). The authors proposed prognostic assessment of an expected effective equivalent dose for a period of 70 years for people, residing in these areas (0.08-0.45 cSi for the population and 0.6-3.2 cSi for mechanics).

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[The regulations of radiation exposure, radiation loads on the population and the medical consequences of the Chernobyl accident].

The paper is concerned with analysis of strategy of the regulation of radiation exposure of the population and the practical use of the levels of intervention in different phases after the Chernobyl accident. The author represents data on the levels of whole-body irradiation of the population in the areas under strict control, and dose exposure of the thyroid in children and adults. Mean individual and collective doses of whole-body irradiation over the period of 1986-1989 and predictable dose exposures were assessed. Some data on probable pathology of radiation genesis in the population in affect on 1990 were considered.

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[Clinico-electrocardiographic evaluation of the state of the cardiovascular system inpersonnel engaged in liquidating the consequences of the accident at the Chernobyl Atomic Power Station].

The paper is concerned with analysis of the results of clinico-electrocardiographic investigation of 107 rescuers, engaged in the elimination of the effects of the Chernobyl accident. A high percent (27.2%) of the detectability of borderline arterial hypertension was noted among the rescuers (aged to 39) that was determined by a strong psychoemotional tension resulting from work and radiation phobia.

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[The psychic status and work capacity of the victims of the accident at the Chernobyl Nuclear Power Station in the period of recovery from and near-term consequences of acute radiation sickness].

Analysis of the results of clinicopsychological investigation of persons developing ARS (I-III degree of severity) as a result of the Chernobyl accident has shown that 4-6 mos. after the exposure the psychic status and mental working ability of the affected persons showed close correlation with a degree of ARS. In 12-18 mos. profession and adequate employment played a decisive role in the formation of unfavorable psychic conditions and limited working ability. Later on in 2.5-3 years after exposure a decrease in psychic working ability, the development of unfavorable psychic conditions was noted more frequently in patients with ARS of more severe types and in examinees of older age. At all stages of rehabilitation personality traits of the affected persons play an important role in the revival of working abilities.

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[Functional status of the pituitary-thyroid system in children and adolescents exposed to radiation as a result of the accident at the Chernobyl Nuclear Power Station].

The paper is concerned with the results of a follow-up over the period of 1986-1989 of function of the hypophyseo-thyroid system in children and adolescents (approximately 6000 persons), residing in the South-West of the Kaluga Region, where radiation fallouts were observed after the Chernobyl accident. The results were based upon the analysis of medical examinations and determination of the blood levels of TSH, T4 and T3. A certain functional activation of the thyroid system was observed in a majority of the examinees. A conclusion has been made of a necessity of a long-term follow-up of the thyroid of persons who received radioactive iodine in childhood.

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[The level of lymphocytes in the peripheral blood as a criterion of the degree of severity of acute radiation sickness (based on materials from the accident at the Chernobyl Nuclear Power Station)].

A study was made of the peripheral blood lymphocyte level as a function of gamma-radiation dose after single gamma-radiation attack resulted from Chernobyl disaster. After the initial drop an average level of lymphocytes was stabilized by day 2 after exposure and no further systematic decrease in the number of lymphocytes occurred. The accuracy of prognostication of the severity of acute radiation sickness, determined by the average lymphocyte level on days 3-6 amounted to as low as 50%. However, when the neighbouring, by the severity, groups of patients were taken into account, the accuracy was 88%.

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[Chromosomal restructuring of three species of chiromonads from the Chernobyl region (Diptera, Chironomidae)].

Chromosomal polymorphism of three species--Chironomus plumosus, Ch. balatonicus and Glyptotendipes glaucus collected from the Chernobyl Zone demonstrated following characteristics: lack of standard karyotype, the presence of hetero- and homozygotic inversions (seven para- and one pericentric), increase in centromeric heterochromatin (55% larvae in homo- and heterozygotic state), the presence of B chromosomes (21%)--in Ch. plumosus; only two larvae had a standard karyotype, the rest demonstrating hetero- and homozygotic inversions (eleven paracentrics), reciprocal translocations of the IVF and IA arms, B chromosomes (5.4%), increase in telomeric (43.6%) and centromeric (1.8%) heterochromatin--in Ch. balatonicus; two types of hetero- and homozygotic inversions, replacement of standard sequences in C and D for inversional homozygotic ones--in Gl. glaucus.

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[Proteins of the lupin family, binding molybdenum, tungsten, and radionuclide effluents from the Chernobyl Atomic Energy Station].

Yellow lupine seeds were found to contain two proteins and a low molecular weight fraction possessing the ability to bind Mo, W and radionuclides from the Chernobyl nuclear power in vivo and the 185W isotope in vitro. These proteins differ in their electrophoretic mobility. The electrophoretically less mobile protein undergoes proteolytic degradation; the proteolytic product retains the ability to accumulate microelements.

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[Results of a follow-up of participants in the liquidation of the effects of the Chernobyl AES accident].

The paper is concerned with the results of analysis of a clinico-laboratory study of persons (residents of Armenia) who took part in the elimination of the effects of the Chernobyl accident. Investigation of general morbidity revealed no correlation with exposure to ionizing radiation. The symptom complex of pathological changes included CNS functional disorders, a transition from the hypokinetic type of a heart response to exercise to the normokinetic one, lowered immune status and tissue peripheral blood flow, unmarked hematological and biochemical shifts, suggesting suppression of the body antioxidant system.

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[The structural-dynamic characteristics of the reactive psychoses in persons subjected to ionizing radiation exposure as a result of the accident at the Chernobyl Atomic Electric Power Station].

Thirty case histories were examined of patients who participated in liquidation of sequels of the Chernobyl disaster or inhabiting contaminated territory during the first months after the catastrophe. Of them eleven showed reactive states accompanied by psychopathological disorders. The psychotic disorders in these subjects were simple and concrete by their clinical course, developed mainly during the first 2-4 months after the disaster when the stressogeneity was maximal. This conclusion is confirmed by the fact that of 148 persons subjected to radiation effects and treated at a Kiev Mental hospital from 1986 through 1990 reactive psychoses were observed only in 11 cases.

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[Level and pattern of morbidity of children residing in the Ukrainian S.S.R. exposed to radioactive pollution as the result of the Chernobyl AES accident].

It has been shown that there is a significant increase in total morbidity in children residing in the areas exposed to radioactive pollution due to the accident at the Chernobyl Atomic Power Station. This is due largely to higher morbidity of respiratory disease. There is also an increased in the incidence of digestive diseases, iron-deficiency anemias, mental disorders. The recorded growth of childhood morbidity in the areas examined is much higher than that in the children living in other areas unexposed to radioactive pollution.

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[Immunological aspects of the study of contingents of population exposed to ionizing radiation effects as the consequence of the Chernobyl AES accident].

The immune system was examined in those who participated in the liquidation of accident sequelae at the Chernobyl Atomic Power Station and the population exposed to ionizing radiation. Alteration in surface antigenic markers of basic regulatory subpopulations of immunocompetent cells and metabolic changes are caused by radiation and co-existent somatic diseases. Typing for HLA antigens and proteins with a genetically determined phenotype revealed characteristic features of their distribution for the general population.

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[Clinico-immunocytological characteristics of leukemia in persons exposed to ionizing radiation effects due to the Chernobyl AES accident].

A total of 18 patients with acute leukemia from those exposed to radiation when they had liquidated the consequences of the accident at the Chernobyl Atomic Power Station were examined. Sixteen of them had acute myeloblast cell leukemia, one had acute lymphatic leukemia, and another one had acute promyelocytic leukemia. A complex of hematological, immunocytological, and cytochemical findings, as well as leukocytic and erythrocytic genetically determined antigen typing were used for diagnosis. Signs of severe vegetovascular dystonia was found to be followed by acute leukemia in all the patients. A relationship was established between the therapy resistance and the HLA antigen homozygosity in combination with genetically-determined low reactivity. There were no significant differences between the parameters in question and those in patients with acute leukemia who had been studied in the preaccident period.

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[Characterization of irradiation levels of the population in the controlled areas 4 years after the Chernobyl AES accident].

Based on a summary of the radiation and hygienic control data, the authors suggest empiric mathematic models depicting the dynamics of the formation of external and internal radiation doses within the first 4 years after the Chernobyl NPP accident. It has been established that in the areas of rigid control, the mean radiation dose amounted, within the period indicated, to 3.5 kev, that due to external radiation to 2.67 kev; the collective dose for 273,00 population living in those areas constituted 9.6 kev.

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