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At least 1,027 records · Page 57Linked to original sources
PubMed2006

An in vitro assessment of the sealing ability of resilon/epiphany using fluid filtration.

The aim of this in vitro study was to compare the sealing ability of Resilon/Epiphany to gutta-percha and Roth or AH Plus sealers. Leakage of the obturated roots was measured using the fluid filtration technique. There were eight groups of 12 teeth each. Group 1: obturated with Resilon/Epiphany; group 2: obturated with gutta-percha/Roth, allowed to set for 3 wk; group 3: obturated with gutta-percha/Roth; group 4: obturated with Resilon/Epiphany using a single cone; group 5: obturated with Resilon cones without using primer/sealer (positive control); group 6: obturated with gutta-percha/AH Plus; group 7: same as group 6, but allowed to set for 8 h; and group 8: sealed on the outside with three layers of nail varnish (negative control). The results showed that only the positive control (group 5) leaked significantly more (p < 0.05) than the other groups. There was no effect of time on leakage. Resilon/Epiphany was no better than gutta-percha/Roth or gutta-percha/AH Plus at sealing root canals.

Analysis of Variance↗
PubMed2006

The quantitative evaluation of apical sealing of four endodontic sealers.

The aim of this in vitro study was to evaluate the apical seal obtained with four root canal sealers: Rocanal 2, Sealapex, AH Plus, and RC Sealer. Forty root canals were prepared using the step-back technique. The specimens were divided into four groups of 10 samples and obturated by laterally condensed gutta-percha with one of the tested sealers. The computerized fluid filtration method was used for evaluation of apical sealing properties. The quantitative apical leakage of each specimen was measured after 7, 14, and 21 days. Statistical analysis indicated that the apical leakage of all sealers used in this study decreased gradually from 7 days to 21 days (p < 0.05). Sealapex showed better apical sealing than the other sealers at 7, 14, and 21 days (p < 0.05). RC Sealer, AH Plus, and Rocanal 2 showed similar apical leakage values at every period (p > 0.05).

Analysis of Variance↗
PubMed2006

Improving the performance of EndoREZ root canal sealer with a dual-cured two-step self-etch adhesive. II. Apical and coronal seal.

This study tested the hypothesis that the seal of EndoREZ may be improved with an adhesive-modified technique. Instrumented single-rooted teeth were filled with: (a) Warm vertical compaction with AH Plus (control); (b). EndoREZ with master cones and passive application of accessory cones; (c) Application of Clearfil Liner Bond 2V before EndoREZ and gutta-percha condensation. Leakage was assessed by fluid filtration at 10 psi before root resection and after 3 to 12 mm apical resections. Statistical analyses revealed significant differences in filling technique and resection lengths. EndoREZ exhibited significantly higher overall leakage, while no difference was found between AH Plus and the adhesive-modified EndoRez technique. Apical resection of EndoREZ to 12 mm exhibited more leakage than all other interactions, but was not significantly different from the same material resected to 9 mm. Although EndoREZ exhibited an acceptable apical seal, its coronal seal may be improved with the use of a dual-cured self-etch adhesive.

Analysis of Variance↗
PubMed2006

Influence of moisture on the apical seal of root canal fillings with five different types of sealer.

The aim of this study was to evaluate the influence of moisture on apical leakage using five different types of sealer. There were 120 single-rooted teeth instrumented to .02/#60 and randomly assigned to 10 experimental groups, one control group (AH Plus, lateral condensation) (n = 10) or positive/negative controls (n = 5). Before obturation teeth were dried thoroughly, followed by recontamination with moisture in a wet chamber (moist groups; 37 degrees C for 7 days). The teeth of the experimental groups (a, dry; b, moist) were obturated with sealer (groups 1, AH Plus; 2, Apexit; 3, Ketac-Endo; 4, RoekoSeal; 5, Tubli-Seal) and a single gutta-percha cone .02/#55. Teeth were centrifuged (30 x g for 3 minutes) in 5% methylene blue. Linear dye penetration was measured under a stereomicroscope. Moisture led to less microleakage for Apexit, RoekoSeal, and Tubli-Seal and higher values for AH Plus and Ketac-Endo. Multifactorial ANOVA displayed a significant dependence of leakage on sealer (p < 0.001) and the combination sealer or moisture (p < 0.01). It depends on the sealer type in which way moisture affects the apical seal.

Analysis of Variance↗
PubMed2005

Levels and temporal trends of PCDD/PCDFs and non-ortho PCBs in ringed seals from East Greenland.

The levels and temporal trend of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and non-ortho substituted PCBs (c-PCBs, i.e. CB77, CB126 and CB169) were determined in ringed seal blubber from central East Greenland collected in 1986, 1994, 1999 and 2003, respectively. Since 1986 the concentrations of PCDDs, PCDFs and c-PCBs all show a decreasing trend. The annual decreases were estimated to 5.2% and 5.3% for pg/g WHO-TEQ ww of PCDD/Fs and c-PCB, respectively. The annual median concentrations of PCDDs ranged from 5.4 to 24.4 pg/g WHO-TEQ ww and those of PCDFs from 2.5 to 5.1 pg/g WHO-TEQ ww. Compared to PCDD/Fs concentrations in ringed seals from other Arctic areas the levels of PCDD/Fs found in 1986 were the highest recorded. The annual median concentrations of c-PCBs decreased 24.2 to 9.1 pg/g WHO-TEQ ww. The levels of c-PCBs observed in 1986 are similar to levels found in ringed seals from Svalbard in 1990 and from eastern Hudson Bay in 1989-1992. The dominant and most TEQ-contributing PCDD congener was 1,2,3,7,8-PeCDD. CB126 was the dominating and most TEQ-contributing c-PCB congener. The concentrations of PCDDs, PCDFs and c-PCBs were highly significantly inter-correlated. Principal component analysis of the PCDD/PCDF congeners and c-PCBs was performed to analyse the pattern of compounds during time.

Adipose Tissue↗
PubMed2005

Effect of water turbidity on the visual acuity of harbor seals (Phoca vitulina).

The underwater visual acuity (the angle subtended by the minimal resolvable line width of high contrast square wave gratings at a viewing distance of 2m) of two male harbor seals was determined at different levels of water turbidity. Starting with visual acuity angles of 5.5' and 12.7' in clear water we found visual acuity to decrease rapidly with increasing turbidity at rates of 7.4' and 6.0' per formazin nephelometric unit (FNU). Besides the individual differences in visual performance of the harbor seals tested, our results reveal a dramatic loss of visual acuity even at moderate levels of turbidity. At sites in the German Wadden Sea, where harbor seals are known to roam and forage, we measured turbidity levels exceeding 40FNU. These data suggest that turbidity has to be considered as an important factor in the sensory ecology of pinnipeds.

Animals↗
PubMed2006

Visual fields and eye movements in a harbor seal (Phoca vitulina).

The boundaries of the visual fields of a harbor seal were measured using static perimetry. In the seal lying on a plane surface (fixation point "0 degrees" straight ahead at eye-level), the visual field with fixed eyes extended over 208 degrees horizontally and reached from -12 degrees to +69 degrees vertically. The binocular visual field amounted to 67 degrees. Eye movements of 12 degrees (+/-2) degrees to both sides and 64 degrees upwards could be induced. In the seal performing eye movements, a visual field of 210 degrees in the horizontal plane and 121 degrees to the dorsal side was determined. From the measured eye movements, a visual field of 232 degrees in the horizontal plane appears possible.

Animals↗
PubMed2005

Electrosurgical bipolar vessel sealing for radical abdominal hysterectomy.

OBJECTIVE: We analyzed the use of an electrosurgical bipolar vessel sealing system for radical abdominal hysterectomy. METHODS: We compared operating time, transfusion requirements and other surgical parameters in 52 patients undergoing radical abdominal hysterectomy with systematic pelvic +/- paraaortic lymphadenectomy for stage IB1-IIB cervical cancer between January 2001 and June 2004. At 21 operations between January 2001 and March 2002, the parametrium, paracolpos and vaginal cuff were resected with clamps and the pedicles suture ligated; 31 operations between November 2001 and June 2004 were done with a bipolar vessel sealing system (LigaSure Vessel Sealing System, Valleylab, Boulder, CO). Four surgeons did all operations. Data were compared with the t test. RESULTS: Patients operated with the LigaSure system received fewer packed RBC transfusions than those operated with clamps (mean, 0.61 +/- 1.1 vs. 2.14 +/- 2.6 units, respectively; P = 0.01), even when looking at patients who underwent only pelvic (without paraaortic) lymphadenectomy (mean, 0.52 +/- 1.1 vs. 1.29 +/- 1.2 units, respectively; P = 0.02). The transfusion rate in the two groups was 26% (8/31) and 67% (14/21), respectively (P < 0.05). Operating time did not differ significantly (199 +/- 33 vs. 213 +/- 45 min, respectively). There were no significant differences between the groups in number of pelvic nodes removed, febrile morbidity, postoperative stay, or days until residual urine <100 ml. One patient in the LigaSure group developed a ureterovaginal fistula that resolved with stenting. CONCLUSION: The LigaSure system appears useful to reduce blood loss at radical abdominal hysterectomy.

Electrocoagulation↗
PubMed2003

A novel technique for self-sealing, wedge-shaped pars plana sclerotomies and its features in ultrasound biomicroscopy and clinical outcome.

PURPOSE: To investigate a new type of self-sealing pars plana sclerotomy clinically and by means of ultrasound biomicroscopy and to compare the outcome with conventionally sutured sclerotomies. DESIGN: Prospective, nonrandomized clinical trial. METHODS: Twenty-one patients underwent pars plana vitrectomy either with (control group) or without suturing (study group) at the Institute of Ophthalmology, University Medical Centre Nijmegen, The Netherlands, between January 1 and March 31, 2002. One day and 6 to 8 weeks postoperatively, the sclerotomy sites were studied by clinical examination and ultrasound biomicroscopy. Results were graded according to verbal descriptor scales. RESULTS: The study included 21 patients scheduled for pars plana vitrectomy of one eye. Mean follow-up time was 6.5 weeks (range, 6-8). Three patients were lost to follow-up. Of the remaining patients, 12 had self-sealing wedge-sclerotomies and six were conventionally operated. No intraoperative complications occurred in any participant and no visual loss or postoperative hypotony was observed. On the first day after surgery there was significantly more scleral dehiscence in the control group (P =.012). This divergence disappeared during the follow-up period. All other differences noticed were not statistically significant. CONCLUSIONS: Our novel technique of sutureless wedge-shaped sclerotomy allows the creation of simple, reliable, and self-sealing pars plana openings. Clinical examination and assessment by ultrasound biomicroscopy showed results to be at least as safe as conventionally sutured sclerotomies. This new method allows stable intraoperative ocular pressure conditions and seems promising.

Adult↗
PubMed2000

Mixing collagen with fibrin glue to strengthen the sealing effect for pulmonary air leakage.

BACKGROUND: To strengthen the sealing effect of fibrin glue for pulmonary air leakage, atelocollagen was mixed with the glue and the mixing effect was examined. METHODS: A mixture of fibrinogen and thrombin with atelocollagen was used as a test sample. The concentrations of atelocollagen were adjusted to levels of 0%, 0.375%, 0.75%, 1.1%, and 1.5%. We next performed air leakage tests on a plastic cap with pin holes and swine lung and also measured the elasticity and the adhesion strength. RESULTS: The pressure required to rupture the sealant on a plastic cap with pin holes increased as the concentration of atelocollagen increased, and the bursting pressures were significantly higher in the glue with 0.75%, 1.1%, and 1.5% of atelocollagen than in the glue without atelocollagen (p < 0.01 and p < 0.001). The air leakage pressure on the swine lung was significantly higher in the glue with 0.375%, 0.75%, and 1.1% of atelocollagen than in the glue without atelocollagen (p < 0.05 and p < 0.01), and it was the highest with 0.75%. The elasticity of the glue significantly increased as the concentration of atelocollagen increased (p < 0.001). However, the adhesion strength of the glue significantly decreased as the concentration of atelocollagen increased (p < 0.05 to p < 0.001). CONCLUSIONS: The mixing of atelocollagen with fibrin glue more effectively sealed pulmonary air leakage due to an increased elasticity of the glue while its adhesion strength decreased. The optimal concentration of atelocollagen in the fibrin glue to obtain the best sealing effect was 0.75%.

Animals↗
PubMed1995

Membrane potential and input resistance are ambiguous measures of sealing of transected cable-like structures.

For many years, membrane potential (Vm) and input resistance have been used to characterize the electrophysiological nature of a seal (barrier) that forms at the cut end of a transected axon or other extended cytoplasmic structure. Data from a mathematical and an analog model of a transected axon and other theoretical considerations show that steady-state values of Vm and input resistance measured from any cable-like structure provide a very equivocal assessment of the electrical barrier (seal) at the cut end. Extracellular assessments of injury currents almost certainly provide a better electrophysiological measure of the status of plasma membrane sealing because measurements of these currents do not depend on the cable properties of extended cytoplasmic processes after transection.

Animals↗
PubMed1997

The use of negative pressure to promote the healing of tissue defects: a clinical trial using the vacuum sealing technique.

A prospective clinical trial from January 1994 to February 1996 evaluated the efficacy of a vacuum sealing technique in dealing with sacral pressure ulcers, acute traumatic soft tissue defects and infected soft tissue defects following rigid stabilization of lower extremity fractures in 45 patients. Polyvinyl foam under negative pressure generates an area of high contact forces at the wound/foam interface. This situation appears to facilitate granulation tissue production while maintaining a relatively clean wound bed. In 84% (38/45) of the patients the use of the vacuum sealing technique following irrigation and debridement decreased the dimensions of the initial wound, thus facilitating healing time and the eradication of any pre-existing infection. Wound closure by granulation, secondary closure, or split thickness skin grafting was achieved in 35 wounds. The vacuum sealing technique is an effective option in the management of infected wounds.

Adult↗
PubMed1999

The use of the angio-seal haemostatic puncture closure device in high risk patients.

The use of the Angio-Seal haemostatic puncture closure device in 45 patients considered to be at increased risk of puncture site complications is described. Successful device deployment occurred in 44 of 50 arteries (88%). Two major complications were associated with, but not necessarily caused by, the Angio-Seal device. Four minor complications were observed. In a subset of 23 patients well enough to mobilize early after their procedure, 17 did so at an average of 2.6 h as opposed to the routine 12-18 h for patients after a procedure involving a 6-8F sheath. Once the initial learning curve has been overcome, the Angio-Seal device is a simple and successful method of achieving arterial haemostasis following catheterization and is associated with a low risk of complications. At present we would recommend its use for high risk patients only, as manual compression is effective in the majority of routine cases.

Aged↗
PubMed1989

Centrifugal counter-current partition chromatography with helical coil rotor. Simplified counter-current chromatography with a rotating face-seal.

A centrifugal counter-current partition chromatograph has been developed and tested in order to simplify earlier counter-current chromatographic (CCC) procedures. It includes a helical coil rotor and a rotating face-seal. The rotor is designed to be adapted in an ordinary laboratory centrifuge for toroidal coil CCC. Twisting between the inlet and outlet tubing is avoided by using the rotating seal in the rotor. The seal is placed between the rotor, on which helical coils are mounted, and a newly designed centrifuge lid. This chromatographic rotor, rotating simply around its own axis, has simplified a previous CCC device in which a coil planet mechanism is used to avoid tube twisting whilst retaining the capability for chromatographic separations. Results for separations of nystatin, dinitrophenylamino acids and Poly I:C were comparable to those obtained by liquid chromatography and the previous CCC procedure.

Amino Acids↗
PubMed1999

Replacement of the proximal aorta and aortic valve using a composite bileaflet prosthesis and gelatin-impregnated polyester graft (Carbo-Seal): early results in 143 patients.

OBJECTIVE: We report the combined early results from two centers in the United Kingdom using a composite conduit consisting of a bileaflet mechanical valve incorporated into a gelatin-impregnated, ultra-low porosity, woven polyester graft (Carbo-Seal; Sulzer Carbomedics, Inc, Austin, Tex). METHODS: Between August 1992 and March 1997, 143 patients underwent aortic root replacement with the Carbo-Seal composite prosthesis. The indication for surgery was acute type A dissection in 31 (22%), chronic type A dissection in 9 (6%), ascending aortic aneurysm without dissection in 100 (70%), and false aneurysm of the ascending aorta in 3 (2%). Twenty-seven patients (19%) had undergone previous sternotomy, and 40 (28%) were seen as emergencies. Concomitant procedures were performed in 38 (27%), including 18 aortic arch or hemiarch replacements. Total follow-up is 270 patient-years. Follow-up is 100% complete. RESULTS: The early (30-day) mortality was 7% (10 patients). Permanent neurologic events occurred in 2%. At a mean follow-up of 23 months, 94% of survivors were in New York Heart Association functional class I. Freedom from reoperation was 97.2% +/- 1.6% (1 standard error [1 SE]) at 12 months and 95.7% +/- 2.2% at 48 months. Including early mortality, survival was 90.1% +/- 2.6% at 12 months and 83.1% +/- 3. 5% at 48 months. CONCLUSIONS: Aortic root replacement with use of the Carbo-Seal prosthesis can be undertaken with a relatively low early mortality and morbidity. A low reoperation rate and high intermediate-term survival can be expected, but continued follow-up is needed to determine the long-term efficacy of this prosthesis.

Aged↗
PubMed1998

BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation.

Secretory proteins are cotranslationally translocated across the mammalian ER membrane through an aqueous pore in the translocon while the permeability barrier is maintained by a tight ribosome-membrane junction. The lumenal end of the pore is also blocked early in translocation. Extraction of soluble lumenal proteins from microsomes and reconstitution with purified proteins demonstrate, by fluorescence collisional quenching, that BiP seals the lumenal end of this pore. BiP also seals translocons that are assembled but are not engaged in translocation. These ribosome-free translocons have smaller pores (9-15 A diameter versus 40-60 A in functioning translocons) and are generated when ribosomes dissociate from functioning translocons with large pores. BiP therefore maintains the permeability barrier by sealing both nontranslocating and newly targeted translocons.

Adenosine Diphosphate↗
PubMed1992

Sealing ability of Thermafil with and without sealer.

The purpose of this study was to evaluate the apical sealing ability of root canals filled using three obturating techniques. Sixteen maxillary first molars were obturated with Thermafil, 16 with Thermafil and a ZOE sealer, and 16 with laterally condensed gutta-percha. Two canal instrumentation methods were used, conventional step-back preparation with K-Flex files and traditional instrumentation combining reaming with reamers and filing with K-Flex files. Following obturation, the teeth were prepared for evaluation of the seal using India ink and a Profile Projector. The depth of penetration of the dye was statistically evaluated for each of the three roots with an analysis of variance. For sealing ability, there was no significant difference at the p < 0.05 level between the conventional step-back preparation and the traditional instrumentation technique. However, a significant difference was present at the p < 0.05 level for the obturation techniques. The mean linear dye penetration for the Thermafil technique was greater than that for lateral condensation.

Dental Leakage↗
PubMed1995

Apical sealing ability of a new glass ionomer root canal sealer.

This study compared the sealing ability of Ketac Endo with and without smear layer and Tubli Seal. Thirty upper central incisors and canines with straight canals were instrumented and randomly divided into three equal groups of 10. All teeth were obturated with laterally condensed gutta-percha. An additional group of five teeth with unobturated++ root canals served as positive controls. The sealers were Tubli Seal (group A), Ketac Endo (group B), and Ketac Endo preceded by the removal of the smear layer (group C). The teeth were immersed in India ink for 7 days, centrifuged for 5 min at 3000 rpm, cleared, and then examined under a light microscope at X 50 magnification. The mean value of ink penetration for group A was 0.14 mm, for group B 0.24 mm, and for group C 0.48 mm. No statistically significant differences were observed among groups (p > 0.05).

Acrylic Resins↗