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[Initial experience with transluminal laser recanalization in patients with stenosing arteriosclerosis of the lower extremities].

Early experience with transluminal application of low-intensity laser beam (632 nm) to treat atherosclerotic vascular occlusions in 23 patients with combined disorders (Leriche's syndrome and coronary heart disease) is summed up. The beam was carried to the site of occlusion through special laser catheters developed at the A. N. Bakulev Institute of Cardiovascular Surgery (USSR Academy of Medical Sciences). Objective assessment of blood flow recovery in the ischemized limbs was based on angiography, hemodynamic studies, volumetric sphygmography combined with ultrasonic dopplerography and digital subtraction angiography.

Adult↗

[Arterial recanalization using the laser. A technic for the future?].

On the basis of two years' experience, a technique for the use of percutaneous endoluminal continuous emission Nd-YAG laser has been developed for arterial recanalisation. The effectiveness of this type of laser has been demonstrated in a large number of clots and atheromatous plaques, including calcified plaques. A balloon catheter gives a coaxial position of the fiber in center of the artery. Infusion of a blood solution containing 3 g of haemoglobin/100 ml at a rate of 20 ml/minute limits the thermal parietal lesions, improves the conditions of laser treatment and eliminates any risk of arterial perforation. No embolic debris is collected down-stream. Recanalisation of long arterial segments in amputated legs was performed prior to the human application. Ten patients have been treated with no mortality and virtually no morbidity. The narrowness of the reformed arterial lumina resulted in early re-thrombosis in the first 5 cases, requiring balloon modelling to ensure patency with a follow-up of 1 to 3 months in the 5 following patients.

Aged↗

[Regression of residual coronary stenosis after recanalization by fibrinolysis in myocardial infarction. Quantitative analysis of coronary angiography immediately after obstruction removal, at a 15-day and 3-month follow-up].

There seems to be a high risk of reobstruction after local fibrinolytic therapy in myocardial infarction because the severity of the residual stenosis. However, it is quite common to observe a significant improvement of these stenoses at follow-up coronary angiography. Also, one may demonstrate a patent coronary artery after initial failure of the recanalisation procedure. The aim of this research was to study objectively the outcome of the residual coronary stenosis after intracoronary fibrinolytic therapy during myocardial infarction. The degree of stenosis expressed as a percentage reduction of the average diameter of the vessel measured in two perpendicular incidences was assessed immediately after initial fibrinolytic therapy, and at 15 days and 3 months' follow-up. The study group of 31 patients was divided into two subgroups: group I (16 patients) with successful revascularisation and a patent vessel at the first control; and group II (15 patients): unsuccessful revascularisation or with reobstruction at the first control angiography (2 cases). The coronary angiographies were interpreted by an observer who had no knowledge of the patients or of the order of the investigations. In group I, the degree of stenosis decreased from 74 +/- 18 p. 100 to 64 +/- 16 p. 100 (p less than 0.05) at the first control, and then to 47 +/- 24 p. 100 (p less than 0.001) at the second control (less than 50 p. 100 in 7 cases).(ABSTRACT TRUNCATED AT 250 WORDS)

Arterial Occlusive Diseases↗