Indications for the treatment by plastic surgery of the effects of radiation and radiolesions on the skin.
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The paper is devoted to the development of a mathematical model for describing probabilities of occurrence of radiation complications on the skin (as well as in other normal organs and tissues) during its irradiation with homogeneous and inhomogeneous dose fields as a function of an irradiated skin area. The model naturally necessitates the isolation of an equivalent dose (an equidosimetric value) introduced by I. B. Keirim-Marcus which can be effectively used for comparison of homogeneous and inhomogeneous dose fields in normal organs and tissues. The development of mathematical models describing probabilities of occurrence of radiation complications in normal organs and tissues opens up new opportunities for improvement of methods of cancer radiotherapy design.
Radiation ulcera are a permanent source of danger. Their treatment may be long and difficult. Surgical competence is the clue to treatment. Conservative treatment is justified only in the beginning and for short periods. The goal of surgery is excision of damaged tissue and plastic cover with healthy skin. The technique will have to be chosen according to findings and localisation.
The process of epithelialization and the antiseptic effect of nucliderm-gel applied locally have been studied on 63 oncologic patients subjected to radiotherapy. In all cases under study, nucliderm-gel promotes skin epithelialization and has a high antiseptic effect as compared with the drugs applied hitherto.
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The pemphigus vulgaris lesions first developed in a 70-year-old man as a reaction to superficial X-ray treatment of solar keratoses on the forehead.
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