Therapeutic embolization of infantile hepatic hemangioma with polyvinyl alcohol.
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The presence of plasticizers in PVC toys obtained in October 1998 was investigated. Diisononyl phthalate (DINP), di-2-ethylhexyl phthalate (DEHP), di-n-butyl phthalate (DBP), dinonyl phthalate (DNP), diheptyl phthalate (DHP), and di-2-ethylhexyl adipate (DEHA) were detected. The phthalates were found in all of the 68 samples. The principal phthalate found in toys was DINP, which was present in 48 of 68 samples. The DINP content ranged from 15 mg/g to 580 mg/g, and mean content was 308 mg/g. The highest content was found in a pacifier toy. DEHP was present in 20 of 68 samples and the content ranged from 2.0 mg/g to 380 mg/g. The mean content was 162 mg/g. It was found in 60% of domestic toys.
The levels of dibutyl phthalate (DBP), butylbenzyl phthalate (BBP), di-(2-ethylhexyl) phthalate (DEPHP), di-isononyl phthalate (DINP), di-(2-ethylhexyl) adipate (DEHA) and di-isononyl adipate (DINA) were determined in 50 processed foods (ham and sausage, fried dumpling and shao-mai, fish paste products, croquette and fried fish, bread, noodle, pickles, etc.). DBP, BBP, DEHP, DINP, DEHA, and DINA were contained at nd approximately 47.7, nd approximately 16.6, nd approximately 749, nd approximately 358, nd approximately 57.2 and nd approximately 20,200 ppb, respectively. High-level contamination of DINA was found in fish paste products, croquette and shao-mai, presumably because of migration from plasticized wrapping film using for food packaging. We studied the relationship between DINA migration from wrapped PVC film into fried croquette and its standing time after frying. When the croquette was wrapped immediately after frying, the migration from wrapping film into the croquette was highest (36,400 ng/g). On wrapping after standing for 5 min and 30 min, the migration level was reduced to 1/3.5 and 1/14 of the highest level, respectively.
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By pouring-cooling method, five kinds of hydrophilic gels (starch, agar, gelatin, CMC-Na and PVA) were prepared. The characteristics of preparation, tenacity and elasticiey were compared. Taking the PVA gel which features better characteristics as the carrier a plaster of verapamine hydrochloride and a traditional Chinese antitussive and expectorant in the form of plaster were prepared. The behavior of drug-releasing in vitro and curative effect were preliminarily studied. The results show that the PVA gel may be a fine carrier for transdermal therapeutic system.
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The method of immobilization of Bacillus subtilis by using polyvingyl alcohol(PVA) as the carrier of immobilized cells was studied. The effects of conditions of immobilization on the structure and mechanical strength of PVA immobilized cells and the ability for producing alpha-amylase of the immobilized cells were investigated. The comparative test of fermentation by using the immobilized cells with PVA as carrier and the immobilized cells with sodium glyinate as carrier and free cells was carried out in the same condition. The results showed that Bacillus substilis cells were immobilized efficently by PVA and the immobilized cells could normally grow and reproduce and produce alpha-amylase. In the same condition, the activity of alpha-amylase produced boy the immobilized cells was 28% higher than that produced by free cells and 11% higher than that produced by the cells immobilized with sodium glyinate as carrier.