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Liposarcoma of the heart. A case report.

The authors report a tumor of the heart in a 33-year-old man. Preoperative diagnosis was of a cardiac myxoma. Upon operation, the tumor was revealed to arise from the right atrial free wall, occupying most of the atrial and ventricular cavities and causing a noticeable enlargement and obstruction of the tricuspid valve as well as the mentioned cardiac chambers. A smaller part of the tumor was placed on the outside of the right atrial wall, and implants of the tumor in the distal part of the aorta, extending backward to the bifurcation of the pulmonary artery and its branches, were also observed. Histological examination showed a myxoid-type tumor with light and ultrastructural features of liposarcoma. The patient died 13 months after surgery with regional extension of the tumor.

Adult↗

Uptake of technetium-99m DTPA in retroperitoneal liposarcoma.

99mTc-DTPA, a renal agent, has been noted to accumulate in tumors such as neurofibroma, uterine myoma, soft tissue sarcoma, hepatic hemangioma, leiomyosarcoma, and plasmacytoma. We report a case in which uptake of 99mTc-DTPA was demonstrated in a retroperitoneal liposarcoma.

Aged↗

Liposarcoma of the cervix.

The case of a 45-year-old woman with a fungating cervical mass which was diagnosed as liposarcoma is described. She had a recurrence which was excised six months later and there was no clinical evidence of metastasis. No report of a similar case has been found in the African literature and this is probably the first documented report.

Biopsy↗

[Renal liposarcoma: diagnostic and therapeutic considerations].

We report on two cases of renal liposarcoma. The clinical features of this tumor type are described and diagnostic and therapeutic considerations are put forward. The usefulness of CT in the diagnosis of this disease entity is underscored. This permits us to evaluate the response to treatment and furthermore, it permits early detection of recurrence.

Female↗

Retroperitoneal liposarcoma presenting with bilateral leg lymphedema--case report.

The case of a 54-year-old man with a large right retroperitoneal liposarcoma presenting with bilateral leg lymphedema, is reported. Total excision of the tumor resulted in marked reduction of the edema in both legs persisting for four years. Follow-up lymphographies demonstrated lymphatic drainage dysfunction on both sides; nevertheless, the edema did not recur. Based on these findings, a non-compressive hypothesis concerning the evolution of lymphedema in this case is postulated.

Follow-Up Studies↗

[Liposarcoma of the renal sinus].

The authors describe a case of liposarcoma of the renal sinus, a relatively uncommon tumor site. We briefly review its pathogenesis and underscore the importance of the preoperative differential diagnosis, particularly from other tumor masses that are often difficult to distinguish.

Aged↗

[Pulmonary metastasis with left intra-atrial extension of liposarcoma. Apropos of a case].

The direct extension of a neoplastic thrombus of the pulmonary veins into the left atrium is extremely rare. The authors report the case of a pulmonary metastasis from a liposarcoma of the thigh extending into the pulmonary veins and prolapsing into the left atrium. The patient was successfully treated by tumorectomy under cardiopulmonary bypass then by left upper lobectomy.

Adult↗

Primary liposarcoma of the omentum: a rare intra-abdominal tumour.

Two cases of primary omental liposarcoma are described, each presenting in a different manner, thus emphasising the spectrum of clinical features associated with this condition. Treatment guidelines are laid down based upon a review of the world literature. The role of radical surgical excision in the management of this often well-encapsulated but highly malignant tumour is emphasised.

Adult↗

[Atypical lipoma, floret-like pleomorphic variant. A lipomatous lesion simulating a liposarcoma].

A case of submucous lump of the majus labium of a 56 year old female has reported. This is a composite lesion which shows a loose connectival texture and a high cellularity with spindle cells, multivacuolated cells of irregular shape and hyperchromatic nuclei; moreover, there are characteristic multinucleated floret-like cells. This is a particular variant of Atypical Lipoma defined as Pleomorphic Lipoma by Enzinger. Despite this ominous cellularity, the lesion is perfectly benign. The small size and the superficial site are the majors elements of good prognosis. In retroperitoneal localization lesions with similar histologic presentation and of major size show more severe prognosis and are classified as Low Grade Well Differentiated Liposarcoma.

Diagnosis, Differential↗

[Liposarcoma in childhood. Report of an exceptional case. Review of the literature].

This paper describes a case of liposarcoma of exceptional paratesticular location (first in the literature described in infancy). The case corresponds to a 5-year-old boy. The influence of the histology, location of the tumour and possibility of complete surgical exeresis is fundamental with regard to prognosis and evolution. Pediatric experience is extremely limited and we may superimpose the treatment in children of that carried out in adults (more case histories), in whom multimodal therapy (surgery, radiotherapy, chemotherapy) concludes with encouraging results. The updating of previously published cases reveals the predominance of myxoid histology, a lower index of relapses in infancy and a high peak of incidence in early infancy.

Child, Preschool↗

[Liposarcoma in children. Apropos of 3 cases and a review of the literature].

Liposarcoma is an uncommon tumour in childhood. Three cases are reported. Two patients remain alive and well without local recurrence or metastasis following the initial treatment, however one patient died as a result of direct tumour extension despite chemotherapy. A review of the literature revealed the following features: the extremity are the most common location, the predominance of myxoid histology and its best prognosis. The treatment is the complete surgical excision, the efficiency of radiotherapy or chemotherapy has not been formally proved.

Buttocks↗

[Liposarcoma].

During a 12-year period, 10 men and 5 women ranging in age from 22-76 (mean 53 years), were treated for liposarcoma. In 7 the tumor was located in the retroperitoneum, in 5 in the lower extremity and in 1 each, in the back, shoulder and groin. The best results were given by wide excision of the tumor followed by chemo or radiotherapy.

Adult↗

[Spermatic cord liposarcoma].

In a 36-year-old man with a left scrotal mass a tumor was found and excised through an inguinal incision, together with the testis and the contents of the inguinal canal, in continuity. Histological examination showed a liposarcoma of the spermatic cord. Only 55 cases of this rare scrotal tumor have been reported. The literature indicates that while there is a tendency to local recurrence, there have been no reports of distant metastases. It appears that radiotherapy and chemotherapy are not necessary in this condition.

Adult↗

A mediastinal liposarcoma: an illustrative approach to mediastinal tumors.

Mediastinal masses remain an interesting diagnostic and therapeutic challenge for clinicians because of the low incidence of the tumors, frequent lack of symptoms, and the inaccessibility of the tumors for biopsy. An unusual mediastinal liposarcoma with intracavitary cardiac extension is presented to illustrate the approach to mediastinal tumors in general.

Humans↗

[Gigantic liposarcoma of the retroperitoneum].

A case of giant liposarcoma of the retroperitoneum (7.5 kg, diam. 39 x 30 x 18 cm) is reported. The most frequent sites of onset are discussed and stress is laid on the most useful diagnostic investigations. Surgical treatment, the only possibility of treatment for such large tumors, is often not radical and the recurrence rate is high.

Female↗

[Retroperitoneal liposarcoma. Clinical aspects, diagnosis, therapy and prognosis].

Retroperitoneal liposarcoma is a very rare tumor. There are about 250 cases in the world literature. This article discusses our four cases and the literature concerning this rare disease. The emphasis will be on the epidemiology, pathology, clinical presentation, diagnostic evaluation, therapeutic approach, and ultimate prognosis.

Aged↗