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PubMed1987

Multimicrophone adaptive beamforming for interference reduction in hearing aids.

To reduce interference in monaural hearing aids from sound sources that are spatially separated from a target source, we are investigating methods for combining information from multiple microphones. In this paper, we describe an adaptive beamforming method that functions to preserve target signals arriving from straight-ahead of a microphone array while minimizing output power from off-axis interference sources. In a preliminary evaluation of a two-microphone system, sentence intelligibility tests were administered to normal-hearing subjects using processed and unprocessed materials from simulated environments in which the target was on-axis, the interference (speech babble) was 45 degrees off-axis, and the reverberation mimicked that of a living room, a conference room, and anechoic space. Compared to listening through a single microphone, the two-microphone beamformer reduced the target-to-interference ratio required to achieve 50 percent keyword intelligibility by 30, 14, and 0 dB in the anechoic, living-room, and conference-room conditions, respectively. The corresponding improvements over binaural listening (one microphone to each ear) were 24, 9, and 0 dB. Further tests in the living-room environment using the same beam-forming system but with filter impulse responses shortened by a factor of four (which would decrease the adaptation time by a factor of four) decreased the improvement by 5 dB. These results are sufficiently encouraging to warrant further tests involving more realistic reverberant conditions, multiple sources of interference, and time-varying acoustic environments.

Acoustics↗
PubMed1990

Always trainable? never educable? Updating educational expectations concerning children with Down syndrome.

The misperception that school-age children with Down syndrome always function at the trainable (noneducable) level at the time they enter kindergarten, or will assuredly function at the trainable level later in their schooling, continues to restrict their educational opportunities. The academic achievements of children with Down syndrome who participated in four early education studies were examined. Clear evidence of educable-level performance was revealed. The importance of functional indicators of educability that can complement intelligence test results in determining an appropriate educational placement was stressed.

Achievement↗
PubMed1997

Phosphorus-31 magnetic resonance brain spectroscopy of children at risk for a substance use disorder: preliminary results.

The purpose of this exploratory investigation was to evaluate the heuristic potential of 31P magnetic resonance spectroscopy (MRS) in elucidating a neurobiologic component of the liability for a substance use disorder (SUD). We investigated 31P MRS spectra employing chemical shift imaging (CSI) derived from four distinct anatomic brain locations (i.e. frontal, occipital, right parietal, left parietal) in three groups of peripubertal children who are hypothesized to be at increasing levels of familial SUD risk. Specifically, we studied children with a positive paternal family history of SUD and a disruptive behavior disorder (DBD) diagnosis (SUD+/DBD+; n = 10), in contrast, to those with a positive paternal SUD history in the absence of other psychopathology (SUD+/DBD-; n = 13) and matched control children from normal families (SUD-/DBD-; n = 13). In addition, we examined neurocognitive tests of our subjects to determine any associations between cognitive capacities with regional 31P MRS spectra. The highest-risk sample (SUD+/DBD+) demonstrated a diminished proportion of phosphodiesters confined to the right parietal voxel. This right parietal phosphodiester proportion correlated only with the Information Scale score on a standard intelligence test for children. This suggested a relationship between general learning ability and motivation for academic achievement and right parietal physiology in the highest-risk sample. Variations in synaptic pruning could account for this observation.

Adolescent↗
PubMed1976

Accelerated conservation acquisition and IQ gains by blind children.

Because blind chidlren are retarded in the attainment of substance conservation and other Piagetial concepts, it was hypothesized that a learning set training procedure which incorporated both substance conservation and subordinate concepts might accelerate the acquisition of substance conservation itself and promote generalization to weight conservation scores and IQ. To test the hypotheses, 28 blind children aged 8 to 13 (IQ range 62 to 131) were divided into two groups. Their visual capacities ranged from 20/500 in the best eye to total congenital blindness and etiologies were varied, but consisted primarily of cataracts and glaucoma. All children were pretested and posttested on Slosson's Intelligence Test, 40 substance conservation tasks, and 20 weight conservation tasks, which involved both continuous and discontinuous substance and included almost all those found in the literature prior to 1970. A lengthy learning set procedure employing everyday household objects was then used to teach the experimental children conceptual skills that are prerequisites to substance conservation. Finally the learning set procedure was used to teach the concept of substance conservation itself to the children. The trained group exhibited significantly increased substance and weight conservation scores and IQs (all ps less than .005). The control group, which had spent matched periods of time in intellectual enrichment activities failed to improve significantly on any of the dependent variables. The research suggests that acceleration of the development of Piagetian concepts may be profitable enterprise in the case of blind children.

Adolescent↗
PubMed1976

Genetic factors in myopia.

A school population has been screened to locate same-sexed twins with myopia and also to compare intelligence test performance of myopic and nonmyopic individuals. Augmentation of the twin data by a survey of the world literature has led to the identification of a total of 106 MZ twin pairs, 100 of them concordant for myopia, as well as 41 DZ pairs, 12 concordant. Myopic students score eight points higher on IQ tests than nonmyopes, the entire bell shaped distribution curve being shifted to a higher range. The intellectual gain precedes in time the development of nearsightedness.

Adolescent↗
PubMed1995

Neuropsychological deficit and academic performance in children and adolescents following traumatic brain injury.

Evaluated the utility of neuropsychological testing in predicting academic outcome in children 1 year following traumatic brain injury (TBI). Fifty-one school age children who were admitted to hospital after TBI were assessed with a battery of neuropsychological measures at 3 months postinjury. Academic achievement was assessed at 3 and 12 months postinjury. The neuropsychological battery included intelligence testing and measures of memory, learning, and speed of information processing. Academic outcome was assessed in terms of post-TBI changes in reading, spelling, and arithmetic; changes in teacher ratings of school performance; and change in school placement. According to logistic regression analysis, change in placement from regular to special education at 1-year post-TBI was predicted by injury severity and by neuropsychological performance at 3 months post-TBI. Findings suggest that neuropsychological testing is useful in identifying children with special educational needs subsequent to TBI.

Achievement↗
PubMed1999

Recognition of spoken words by native and non-native listeners: talker-, listener-, and item-related factors.

In order to gain insight into the interplay between the talker-, listener-, and item-related factors that influence speech perception, a large multi-talker database of digitally recorded spoken words was developed, and was then submitted to intelligibility tests with multiple listeners. Ten talkers produced two lists of words at three speaking rates. One list contained lexically "easy" words (words with few phonetically similar sounding "neighbors" with which they could be confused), and the other list contained lexically "hard" words (words with many phonetically similar sounding "neighbors"). An analysis of the intelligibility data obtained with native speakers of English (experiment 1) showed a strong effect of lexical similarity. Easy words had higher intelligibility scores than hard words. A strong effect of speaking rate was also found whereby slow and medium rate words had higher intelligibility scores than fast rate words. Finally, a relationship was also observed between the various stimulus factors whereby the perceptual difficulties imposed by one factor, such as a hard word spoken at a fast rate, could be overcome by the advantage gained through the listener's experience and familiarity with the speech of a particular talker. In experiment 2, the investigation was extended to another listener population, namely, non-native listeners. Results showed that the ability to take advantage of surface phonetic information, such as a consistent talker across items, is a perceptual skill that transfers easily from first to second language perception. However, non-native listeners had particular difficulty with lexically hard words even when familiarity with the items was controlled, suggesting that non-native word recognition may be compromised when fine phonetic discrimination at the segmental level is required. Taken together, the results of this study provide insight into the signal-dependent and signal-independent factors that influence spoken language processing in native and non-native listeners.

Adult↗
PubMed1998

[Higher touch and kinesthetic functions in children with former speech/language development disorders: a neuropsychological study].

Two groups of children took part in this study to test the hypothesis that children diagnosed in infancy as specific speech/language-impaired have deficits in tactile-kinesthetic functions: A formerly clinical group of 25 German-speaking pupils with a mean age of 8;7 years (SD 7.1 months) who have previously been identified as specific speech/language-impaired (on average at 4;11 years, SD 10.6 months) and a control group of 25 normal pupils in elementary school without a former or actual speech/language disorder (mean age: 9;2 years, SD 8.3 months). The control group was matched with the formerly clinical group for gender and age. Performance scores of both groups on a nonverbal intelligence test (the Raven's Matrices), on a tactile-kinesthetic subtest (Berliner-Luria-Neuropsychologisches Verfahren f¿r Kinder), and on a developmental language test (Heidelberger Sprachentwick- lungstest) were compared. There was a significant difference (p < 0.05) in the mean tactile-kinesthetic performance of both groups (3.1 vs. 4.0) who present a nearly identical nonverbal intelligence. Thirty-two percent of the formerly clinical group demonstrated a performance below the norm. Analysis of the laterality did not reveal significant differences in performance between left and right hand, neither in right-handers nor in left-handers of both groups. Nevertheless right-handers demonstrated on average a better somatosensory performance with their left hand. Mean language and tactile-kinesthetic performance correlate significantly in the formerly clinical group (r = 0.45, p < 0.05), but not in the control group (r = 0.08). The formerly clinical group was inferior in performance to the normal subjects especially in complex functions as in the tactile discrimination of sharp/blunt and in topognosia.

Child↗
PubMed1982

The politics of nature and nurture.

Scientists' explanations of group differences are based as much on their political values and unconscious needs as on objective data. It is argued that explanations of black-white differences on intelligence tests, deviant patterns of emotional and social behavior, sex differences, and attitudes toward social change and political action as primary prevention, all are influenced by underlying ideologies.

Environment↗
PubMed1981

Sex-role patterns, paternal rearing attitudes and child development in different social classes.

Sex-role patterns, the father's rearing attitude and the child's intellectual and emotional development in different social classes were studied in a randomly selected sample of 58 Swedish unbroken families of a small child. Working class men and women married younger and the women were more often house-wives. Working class men had more often been reared in an "authoritarian" way and more often reared their children in the same way. Upper middle class men had taken a more active part in the care of the child. Working class children scored lower on the intelligence tests, especially the verbal ones and were more often estimated as socially immature.

Adult↗
PubMed1995

Cognitive estimation in neurological disorders.

The Cognitive Estimation Test (CET) was devised by Shallice & Evans (1978) in an attempt to quantify the tendency observed in some patients with frontal lobe lesions to produce bizarre estimates in response to questions to which people do not usually know exact answers (e.g. 'what is the height of a double-decker bus?'), despite performing normally on standard intelligence tests. In the present study, the CET performance of a large number of patients suffering from head injury, brain tumour, ruptured aneurysm (anterior communicating artery and other), multiple sclerosis, dementia, encephalitis, Korsakoff's syndrome and anxiety/depression were compared with CET scores from 150 healthy controls. Patients with Korsakoff syndrome demonstrated significantly impaired CET performance. A subgroup of patients with discrete frontal lesions was compared with a group with localized non-frontal lesions. No significant difference in CET performance was observed between anterior and posterior lesioned patients. The sensitivity of the CET to anterior brain dysfunction is called into question by the present findings.

Adult↗
PubMed1979

[Catamnestic studies of normally intelligent encephalopathy patients among children and adults].

Our studies show that the special features in the psychic development of encephalopaths showing normal intelligence consist in delayed motor, intellectual and educational progress. While motor retardation is reduced with age, as a result of such factors as rhythmical and psychomotor musico-therapy, individual intelligence test results drop more frequently at school age. The drop is less marked in students attending special classes, although they go back to their original schools after grade 4. The trend toward deterioration in intellectual development is reduced with age, i.e. when educational progress as encouraged by society, slows down. Despite their normal performance with regard to intelligence these students markedly lag behind their healthy contemporaries as far as performance at school is concerned.

Adolescent↗
PubMed1998

Determinants of cognitive disorders in Autosomal Dominant Cerebellar Ataxia type 1.

We assessed neuropsychological performances of 22 patients affected by Autosomal Dominant Cerebellar Ataxia type 1. All subjects completed a comprehensive battery of standardized tests requiring a verbal response, without time constraints. In order to verify the hypothesis that disease severity is the major factor in determining the cognitive status in this syndrome, patients were divided into three groups according to the severity of the clinical picture, as evaluated by the Inherited Ataxias Progression Scale (IAPS). Statistical analysis of the three groups' raw scores showed a significant decrement in patients with more severe clinical pictures on verbal short-term memory tasks. A similar trend, but not significant, was seen for general intelligence tests and verbal learning tasks. The decrement of verbal short-term memory could be related to motor speech problems. On the other hand, the decline of cognitive abilities over the course of the Autosomal Dominant Cerebellar Ataxia type 1 was not homogeneous enough to ensure statistically reliable trends. Therefore, this cross-sectional study suggests that the progression of the disease is a necessary factor in determining cognitive decline, but it is not sufficient. Other disease-related factors (age at onset, genotypic variety) could play a critical role: among these, the size of the expanded CAG repeats is significantly related to a decline of verbal intelligence and short-term memory in SCA2 patients.

Adult↗
PubMed2006

Moderate prenatal alcohol exposure and cognitive status of children at age 10.

BACKGROUND: The effects of prenatal alcohol exposure (PAE) on measures of intelligence have been well documented in children with fetal alcohol syndrome. However, deficits in general intellectual ability in children with low to moderate PAE are less well understood. The objective of this study was to assess the association between moderate PAE and cognitive ability in children at age 10 controlling for other prenatal and birth factors, maternal and child psychosocial factors, and environmental characteristics. METHODS: Data were collected as part of the Maternal Health Practices and Child Development Project, a prospective study of prenatal substance use with 636 mother-child pairs. Women were assessed during each trimester of pregnancy and with their children at birth; 8 and 18 months; and 3, 6, and 10 years. Each phase included an evaluation of growth, development, cognitive, and psychological functioning. At age 10, cognitive ability was assessed using the composite score and verbal, abstract/visual, quantitative, and short-term memory area scores of the Stanford-Binet Intelligence Test, fourth edition. Maternal intellectual ability, maternal prenatal and current drug use, maternal and child psychosocial characteristics, demographics, and home environment were included in the analysis. RESULTS: A significant relation was found between alcohol exposure during the first and second trimesters and the composite score of the Stanford-Binet for African American children at age 10. Significant relations were also found for the verbal, abstract/visual, and quantitative subscales. Additional predictors of IQ at age 10 included mother's IQ, home environment, and child's report of depression. CONCLUSIONS: There is a significant association between PAE and cognitive ability at age 10 among African American offspring. There was no relation between PAE and scores on the Stanford-Binet scales among the Caucasian offspring.

Adult↗
PubMedDate not supplied

[So-called sporadic ulcero-mutilating acropathy: neuropsychological study of 10 cases. II].

Ten patients complaining of Sporadic Ulcerating and Mutilating Acropathy (SUMA) of Bureau and Barrière, also known as alcoholic-acrodystrophic neuropathy, were given the Wechsler-Bellevue's intelligence test (form I) and the Rey's memory test for standard psychometric evaluation. Pathologic mental deterioration of an organic type was found in a very large number of cases: 7 out of 10. The psychical picture that has been recognised is of three kinds: I) homogeneous mental deterioration of verbal and performance skills without any important memory feebleness (4 cases); II) partial mental deterioration shown by memory impairment as a single defect (1 case); III) total deterioration: kind I and II together (2 cases). The SUMA organic brain syndrome has not distinctive features as regards to common chronic alcoholism, but one can believe that it reveals itself with a higher frequency. This is likely to be in connection with a high individual susceptibility to the noxious effect of alcohol (wine) intake. Cerebral and peripheral neuronal damage seems to be established with the same developing modality during the time.

Aged↗
PubMed1993

Binaural noise-reduction hearing aid scheme with real-time processing in the frequency domain.

A binaural noise-reduction algorithm for suppressing lateral noise sources was implemented in real-time and tested with normal and hearing-impaired subjects. With this algorithm, frequency bands with interaural time and amplitude differences characteristic for the "target" direction of the desired speech sound reach both ears without any attenuation. However, frequency bands with an interaural time and amplitude difference deviating from these desired values are attenuated. Speech quality assessments as well as speech intelligibility tests demonstrate a significant noise reduction of up to about 5 dB in signal-to-noise ratio for a dummy-head recorded "cocktail-party situation" in an anechoic chamber. For two additional acoustical situations, however, the subjective speech quality from the algorithm degrades with increasing reverberation, while the output from a real-time "dereverberation" algorithm was ranked higher with increasing reverberation. The results with hearing-impaired listeners suggest a combination of both algorithms, while stressing the importance of binaural listening and binaural hearing aids for the rehabilitation of impaired listeners in noisy environments.

Acoustic Stimulation↗
PubMed1991

[Articulatory evaluation after mesopharyngeal reconstruction with the radial forearm flap].

Soft palate and tonsil (mesopharynx) play an important role on articulation and swallowing. We must take care not to restrict these physiological function when we reconstruct the mesopharyngeal defect after cancer ablation. In order not to restrict the postoperative function of mesopharynx, we take it the more important to preserve the function of the residual tissue rather than to rebuild the lost function. We took notice of pliable nature of the radial forearm flap and tried to reconstruct mesopharyngeal defect in five cases with this flap. We analyzed articulatory function and velopharyngeal closure in these cases, postoperatively. Articulatory function was assessed on the results of intelligibility test with 100 Japanese monosyllables. In four cases out of five, about 70% of syllables were accurately heard. According to the Hirose's standard of speech function after the operation of oral and/or oropharyngeal cancer, those four cases were evaluated also to be excellent. Whether the resection was done beyond the uvula or not, proved not to have anything to do with the postoperative speech intelligibility. Although speech intelligibility once went down immediately after the operation, it improved around six months later. The improvement might be due to the following facts; The forearm flap was cicatrized postoperatively, disturbing the mobility. After the softening of the cicatrix began, the flap gradually recovered flexibility, which enabled surrounding structure to move more smoothly. Articulatory dysfunction was characterized as plosives tend to be misunderstood as nasals or affricates. Concerning nasality, the velopharyngeal closure was examined by fiberscope. Perfect closure was seen in two cases, near-perfect in two cases, and insufficient in one case.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed2006

How similar are fluid cognition and general intelligence? A developmental neuroscience perspective on fluid cognition as an aspect of human cognitive ability.

This target article considers the relation of fluid cognitive functioning to general intelligence. A neurobiological model differentiating working memory/executive function cognitive processes of the prefrontal cortex from aspects of psychometrically defined general intelligence is presented. Work examining the rise in mean intelligence-test performance between normative cohorts, the neuropsychology and neuroscience of cognitive function in typically and atypically developing human populations, and stress, brain development, and corticolimbic connectivity in human and nonhuman animal models is reviewed and found to provide evidence of mechanisms through which early experience affects the development of an aspect of cognition closely related to, but distinct from, general intelligence. Particular emphasis is placed on the role of emotion in fluid cognition and on research indicating fluid cognitive deficits associated with early hippocampal pathology and with dysregulation of the hypothalamic-pituitary-adrenal axis stress-response system. Findings are seen to be consistent with the idea of an independent fluid cognitive construct and to assist with the interpretation of findings from the study of early compensatory education for children facing psychosocial adversity and from behavior genetic research on intelligence. It is concluded that ongoing development of neurobiologically grounded measures of fluid cognitive skills appropriate for young children will play a key role in understanding early mental development and the adaptive success to which it is related, particularly for young children facing social and economic disadvantage. Specifically, in the evaluation of the efficacy of compensatory education efforts such as Head Start and the readiness for school of children from diverse backgrounds, it is important to distinguish fluid cognition from psychometrically defined general intelligence.

Adolescent↗