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Changes in the dynamics of tremor during goal-directed pointing.

For successful performance of activities requiring a fine level of manipulative control and dexterity, precise control over the intrinsic oscillations (tremor) in each segment is essential. However, the question of how individuals control (minimize) their tremor during precise postural movements remains unresolved. The aim of this study was to investigate the changes observed in limb tremor during goal-directed postural pointing tasks. Seven subjects attempted to minimize limb tremor during a pointing task whereby progressively greater levels of accuracy were required. Subjects held a small lightweight laser pointer in their extended hand during all tasks, the goal being to maintain the laser emission within a specified target area. Frequency analysis showed that the tremor profile for the hand and index finger was characterized by two prominent frequency peaks, located between 2-4 and 8-12 Hz. When the accuracy requirement of the task increased, there was a significant increase in the amplitude of the 8-12 Hz peak for all segments. Analysis of the time series component of tremor revealed a similar trend with the root mean square (RMS) and approximate entropy (ApEn) of the finger tremor increasing as the accuracy requirement increased. This same pattern was not seen for hand tremor where a small but systematic decrease in both the tremor RMS and ApEn was observed. Overall, it would appear that subjects attempted to reduce tremor at the finger by exerting greater control over the hand (as evidenced by decreased tremor output and increased regularity in the tremor signal). Unfortunately, the consequence of this strategy was that the tremor in the distal effector actually increased. Changes in the tremor output observed as a result of defining an explicit external goal probably resulted from the enhanced visual information provided by the laser emission. However, it would appear that subjects were not able to utilize this feedback effectively to reduce their tremor during the targeting tasks.

Adult↗

Differences in postural control and movement performance during goal directed reaching in children with developmental coordination disorder.

Poor upper-limb coordination is a common difficulty for children with developmental coordination disorder (DCD). One hypothesis is that deviant muscle timing in proximal muscle groups results in poor postural and movement control. The relationship between muscle timing, arm motion and children's upper-limb coordination deficits has not previously been studied. The aim of this study was to investigate the relationship between functional difficulties with upper-limb motor skills and neuromuscular components of postural stability and coordination. Sixty-four children aged 8-10 years, 32 with DCD and 32 without DCD, participated in the study. The study investigated timing of muscle activity and resultant arm movement during a rapid, voluntary, goal-directed arm movement. Results showed that compared to children without DCD, children with DCD took significantly longer to respond to visual signals and longer to complete the goal-directed movement. Children with DCD also demonstrated altered activity in postural muscles. In particular, shoulder muscles, except for serratus anterior, and posterior trunk muscles demonstrated early activation. Further, anterior trunk muscles demonstrated delayed activation. In children with DCD, anticipatory function was not present in three of the four anterior trunk muscles. These differences support the hypothesis that in children with DCD, altered postural muscle activity may contribute to poor proximal stability and consequently poor arm movement control when performing goal-directed movement. These results have educational and functional implications for children at school and during activities of daily living and leisure activities and for clinicians assessing and treating children with DCD.

Child↗

Scaling back goals and recalibration of the affect system are processes in normal adaptive self-regulation: understanding 'response shift' phenomena.

This comment addresses a set of phenomena that have been labeled 'response shift'. We argue that many of these phenomena reflect recalibration of a goal-seeking system and an affect-management system, both of which are involved in normal adaptive self-regulation. In brief, we hold that these systems act as feedback control mechanisms. The reference values for both systems continuously undergo gradual recalibration. Because in most circumstances the adjustments tend to occur with equivalent frequency in both directions, their cumulative effect is minimal. In situations of either unusually prolonged goal attainment (and overattainment) or unusually prolonged adversity (as occurs, e.g., with deteriorating health), the cumulative effect can be substantial. We believe that these latter recalibrations of reference value account for many response shift phenomena. Other such phenomena are accounted for by the principle of hierarchical organization among the self-regulatory goals that comprise the self.

Adaptation, Psychological↗

Fractal correlation of initial trajectory dynamics vanishes at the movement end point in human rapid goal-directed movements.

Many researchers have investigated the variability of discrete goal-directed movements. However, a possible time-dependent property for them has been ignored. We investigated the time-dependent property of the kinematic variability in human rapid goal-directed movements by using fractal analysis. The variability of the peak acceleration had fractal time correlation characterized by a non-negligible frequency-spectral exponent (beta=0.3). This beta value was reduced at the peak velocity (beta=0.2) and nearly reached zero at the peak movement amplitude, indicating that the variability became white noise with no time correlation. A similar result was observed in the progress of the positional trajectory. The functional significance of this phenomenon for the goal-directed task demand is discussed.

Acceleration↗

Are the treatment goals of culturally competent outpatient substance abuse treatment units congruent with their client profile?

This study examines whether organizational treatment goals varied among outpatient substance abuse treatment (OSAT) units identified as providing a level of culturally competent care for African Americans. Cross-sectional data from the 1995 National Drug Abuse Treatment System Survey (NDATSS) was used. Of the nationally representative, stratified sample of 699 units, 618 (88%) participated. Spearman correlation, analysis of variance, Behrens-Fisher t-tests, chi-square, and multivariate logistic regression were used. Culturally competent units, even after controlling for organizational and client characteristics, were more apt than non-culturally competent units to indicate that achieving steady employment, spiritual strength, and physical health were important treatment goals. A congruency exists among culturally competent OSAT units between the client profile, which is more distressful than that for non-culturally competent units, and the orientation of treatment goals, which are more holistic; that is, treating the total individual, rather than the addiction only.

Black or African American↗

Strategy to accelerate progress towards the attainment of international development goals and targets related to reproductive health.

Reproductive and sexual ill-health account for 20% of the global burden of ill-health for women, and 14% for men. The strategy presented in this document is the World Health Organization's first global strategy on reproductive health. It was adopted by the 57th World Health Assembly (WHA) in May 2004. Five priority aspects of reproductive and sexual health are targeted: improving antenatal, delivery, postpartum and newborn care; providing high-quality services for family planning, including infertility services; eliminating unsafe abortion; combatting sexually transmitted infections, including HIV, reproductive tract infections, cervical cancer and other gynaecological morbidities; and promoting sexual health. The strategy was developed as a result of extensive consultations in all regions with representatives from ministries of health, professional associations, non-governmental organizations, United Nations partners and other key stakeholders. It lays out actions needed for accelerating progress towards the attainment of the Millennium Development Goals (MDGs) and other international goals and targets relating to reproductive health, especially those from the International Conference on Population and Development in 1994 and its five-year follow-up. "The strong endorsement of this strategy by the WHA represents an unequivocal message that countries are committed to do all they can to achieve the goals and targets of the ICPD Programme of Action adopted in 1994." (Dr Paul Van Look, Director, WHO Department of Reproductive Health and Research).

Female↗

Goal-directed transesophageal echocardiography performed by intensivists to assess left ventricular function: comparison with pulmonary artery catheterization.

OBJECTIVES: Transesophageal echocardiography (TEE) is a valuable procedure for assessing left ventricular (LV) function, but it has not been widely applied in critical care because of the limited number of intensivists who are trained in echocardiography. This prospective study was designed to evaluate the feasibility of training intensivists to perform a goal-directed, limited-scope TEE to assess LV function in critically ill patients using a pediatric monoplane TEE probe. A secondary goal was to compare the usefulness of the TEE data with that of data obtained by a simultaneous pulmonary artery catheter (PAC). DESIGN: Prospective, blinded. SETTING: University teaching hospital. PARTICIPANTS: One hundred consecutive, intubated, intensive care unit patients. INTERVENTIONS: Five surgical intensivists with no previous background in echocardiography were trained under the supervision of two cardiologists to perform limited-scope TEE using a monoplane pediatric probe. One intensivist (A) reviewed the PAC data and recorded a diagnostic impression and therapeutic plan. A second intensivist (B), blinded to the PAC data, then performed TEE to determine cardiac volume, LV wall thickness, and LV global and regional wall motion. Intensivists A and B reviewed the data from both PAC and TEE, and intensivist A then formulated a new diagnosis and therapeutic plan. MEASUREMENTS AND MAIN RESULTS: Intensivists performed 48 TEE examinations under direct supervision of a cardiologist, and 52 without supervision, but reviewed poststudy. The average duration of TEE was 12 +/- 7 minutes. The intensivists' interpretations of TEE data were deemed correct in 93% of cases for LV wall thickness, 87% for intracardiac volume status, 81% for regional LV wall motion abnormalities, and 77% for global LV function. When the TEE and PAC technologies were compared, it was found that the TEE data disagreed with the PAC evaluation of intracardiac volume in 55% of cases and with the PAC assessment of myocardial function in 39% of cases. The post-PAC therapeutic recommendations were different from the post-TEE therapeutic recommendations in 58% of patients. CONCLUSIONS: Training intensivists in limited-scope, goal-directed TEE, using a pediatric monoplane probe to evaluate LV function, can be done rapidly and safely, and yield data pertinent to management of critically ill patients even in the early stages of skill acquisition.

Adult↗

Cosmetic surgery: surgical tools--psychosocial goals.

What determines patients' goals for cosmetic surgery and their satisfaction with the outcome? Historical trends, body image theory, evolutionary biology, and clinical and experimental psychology each contribute answers. The physical changes that patients seek are typically a means to psychosocial goals. Individual objectives vary, but often share an origin in recurrent painful feelings, thoughts, or experiences. Surgical goals include: (1) changes in emotional states or cognitions; (2) improvement in interpersonal relationships; and (3) an altering of reactions of the larger society. Psychological studies of cosmetic surgery patients have been designed primarily to address two fundamental questions: (1) is there a preoperative psychological profile of cosmetic surgery patients; and (2) does cosmetic surgery produce enduring, beneficial psychological change? The use of specialized screening interview questions, and effective collaboration with mental health providers, help a wider range of patients achieve successful surgical outcomes.

Body Image↗

Will Lake Michigan lake trout meet the Great Lakes Strategy 2002 PCB reduction goal?

The Great Lakes Strategy 2002 establishes the long-term goal that all Great Lakes fish should be safe to eat without restriction. As an indicator of progress toward that goal, the Strategy specifies that lake trout PCBs will decline 25% from 2000 to 2007. We estimated the plausibility of achieving this near-term goal by examining a time-series of Lake Michigan lake trout PCB concentrations from 1972 to 2000. We used two different Bayesian approaches, Bayesian model averaging (BMA) and dynamic linear models (DLM), to model the trajectory of these historical data and forecast concentrations through 2007. Both approaches indicate that the probability of a 25% reduction from 2000 to 2007 is negligible. The most likely lake trout PCB declines predicted by the BMA and DLM over this time period are 6.8% and 8.9%, respectively. Our results suggest that declines in lake trout PCBs will be in the range of 5-10% assuming conditions similar to recent years. This rate of decline will be difficult to discern without adequate data collection. If sufficient data are not gathered to document further declines, then the relaxation of lake trout consumption advisories is indeed a long-term prospect.

Animals↗

Task difficulty, cardiovascular response, and the magnitude of goal valence.

Sixty-four young women expected to perform an easy, moderately difficult, or extremely difficult memory task with the opportunity to earn a small incentive for good performance. Cardiovascular (heart rate, systolic and diastolic blood pressure) and subjective measures were taken immediately prior to task performance. Both systolic blood pressure (SBP) responses and ratings of goal attractiveness were nonmonotonically related to expected task difficulty, with the most pronounced SBP elevations and highest goal attractiveness in the moderately difficult task condition. Product-moment correlations among cardiovascular response measures revealed a strong positive association between systolic and diastolic pressure (but not heart rate) change in the easy condition, positive relationships among all measures in the moderately difficult condition, and no significant correlations in the extremely difficult condition. Subjective measures of arousal were not affected by the task difficulty manipulation. Principal findings are discussed in terms of a theoretical model proposed by Brehm (1979) that states that motivation varies as a nonmonotonic function of the difficulty of goal attainment. Intercorrelations among cardiovascular response variables are considered in terms of their possible indication of the mechanisms underlying blood pressure changes associated with variations in motivation.

Adult↗

Impulsive motor behavior: effects of personality and goal salience.

This experiment used a circle tracing paradigm to extend our recent theoretical development concerning the contributions of extraversion and neuroticism to impulsive performance on continuous motor tasks. Subjects (N = 137) completed the Eysenck Personality Questionnaire and were randomly assigned to 1 of 2 circle conditions: The goal condition provided subjects with a salient behavioral end point for their tracings, whereas the no-goal condition promoted behavioral uncertainty. In both conditions, Ss were asked to trace the circle under neutral and inhibition instructions. Using Gray's impulsivity and anxiety dimensions to group subjects, impulsive subjects under inhibition instructions displayed significantly faster tracing speed than nonimpulsive subjects in the presence of a salient goal, whereas anxious subjects appeared behaviorally impulsive in a situation promoting uncertainty and response conflict. Conceptualizing impulsivity and anxiety in terms of extraversion and neuroticism, with impulsive Ss as neurotic extraverts and anxious Ss as neurotic-introverts, it is proposed that Ss' level of extraversion determines the type of stimuli to which they are responsive, and that level of neuroticism influences the magnitude of this reaction.

Adult↗

The attenuating effect of role overload on relationships linking self-efficacy and goal level to work performance.

The reported research examines the moderating effects of role overload on the antecedents and consequences of self-efficacy and personal goal level in a longitudinal study conducted in an industrial selling context. The results indicate that role overload moderates the antecedent effect of perceived organizational resources on self-efficacy beliefs. They also show that role overload moderates the direct effects of both self-efficacy and goal level on performance, such that these relationships are positive when role overload is low but not significant when role overload is high. Further, the results reveal a pattern of moderated mediation, in which goal level mediates the indirect effect of self-efficacy on performance when role overload is low but not when it is high. Implications for theory and managerial practice are discussed.

Conflict, Psychological↗

When do stereotypes come to mind and when do they color judgment? A goal-based theoretical framework for stereotype activation and application.

The authors describe a theoretical framework for understanding when people interacting with a member of a stereotyped group activate that group's stereotype and apply it to that person. It is proposed that both stereotype activation and stereotype application during interaction depend on the strength of comprehension and self-enhancement goals that can be satisfied by stereotyping one's interaction partner and on the strength of one's motivation to avoid prejudice. The authors explain how these goals can promote and inhibit stereotype activation and application, and describe diverse chronic and situational factors that can influence the intensity of these goals during interaction and, thereby, influence stereotype activation and application. This approach permits integration of a broad range of findings on stereotype activation and application.

Ethnicity↗

Charting WHO--goals for licit and illicit drugs for the year 2000: are we 'on track'?

Both on a global and a regional basis, the World Health Organization (WHO) has set prominent goals for the turn of the millennium on the reduction of harms associated with licit and illicit drugs. Gauging what the world and its different regions are doing with respect to these specific public health goals is hindered by a conceptual problem: there is no clear concept and consistent way of defining or measuring 'harm' related to drugs, licit or illicit. In many instances, 'harm' is equated with substance use prevalence. Often, especially outside the developed world, basic harm data is not even available. Globally, a conceptually clear and consistently applied scheme of harm measurement related to licit and illicit drugs is needed, acknowledging the fact that drug-related harms occur at different individual and social levels as well as over different periods of time. Harms must also be recognized as an outcome of interactions between the substance user, the drug itself, and the physical and social environment. Looking at available macro-indicators of harm, it must be concluded with, we do not seem to be 'on track' globally in reducing harms related to drugs in accordance with the WHO goals. For alcohol and tobacco, trends for increased harm are just starting to show in the developing world, and will worsen over the next couple of decades. For illicit drugs, failing drug control policies have result in dramatically negative developments for public health, especially with respect to HIV infections and drug-related deaths, in the developed as well as developing world.

Alcohol Drinking↗

Satisfaction of members of interdisciplinary rehabilitation teams with goal planning meetings.

OBJECTIVE: To study how satisfied members of interdisciplinary rehabilitation teams are with goal planning meetings. DESIGN: Survey. SETTING: A regional rehabilitation center for people with acute nonprogressive brain injuries in the United Kingdom. PARTICIPANTS: Forty-four rehabilitation professionals who participated in 31 goal-planning meetings held between January 1, 2001, and March 30, 2001. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Responses to a questionnaire about staff satisfaction with rehabilitation team meetings. RESULTS: Forty-four of 46 members of 21 different rehabilitation teams completed the questionnaires. They included 12 occupational therapists, 7 physiotherapists, 7 physicians, 6 nurses, 5 clinical psychologists, 5 speech pathologists, and 2 social workers. Median scores of different domains were as follows: participation, 13; behavior, 20; outcome, 14; and process, 16. Correlations between the participation and outcome domains (rho=.731, P=.01) and the process and outcome domains (rho=.384, P=.05) were significant. None of the domain scores correlated with features of the meetings. Scores given by chairpersons for participation (P=.001) and outcome (P=.047) were significantly higher than those given by other participants. CONCLUSIONS: Professionals were satisfied with the behavior of other participants and the process of goal-planning meetings. Satisfaction with outcome was related to satisfaction with the participation in and the process of the meetings. Chairpersons were more satisfied with the participation domain.

Brain Injuries↗

[Goal-oriented measurement of short-, medium- and long-term effects in pneumological rehabilitation].

UNLABELLED: Assessment of goal-oriented short-, mean-, and long-term effects in pneumological rehabilitation: Despite of increasing quality in rehabilitation, the amount of treatment in pneumological rehabilitation has decreased by 40% in the last few years. A typical mark of quality is determination of individual objectives to reach a goal of therapy. METHODS: In 566 patients (381 male, 185 female, mean age 47.0 year, body mass index 27.5 kg/m2) goals have been assessed by a questionnaire given at the beginning, the end, 6, and 12 months after rehabilitation. The effect size (ES) of single symptoms, defined as difference between initial and following score values, divided by their standard deviation was used as mild (ES < 0.4), mean (ES < 0.8), or strong (ES > = 0.8) effect. Only those patients were considered, who initially rated for "often" and "very often" in a single symptom. RESULTS: At the end of rehabilitation the effect size was strong in 22 of 24 symptoms, mainly nocturnal symptoms. After 12 months 9 symptoms still revealed strong, and 12 mean effect sizes. These mainly again concerned nocturnal symptoms as palpation of the heart, breathlessness, cough, sweating, and headache, but even diurnal tiredness, spontaneously falling asleep, and lack of concentration revealed ES > 0.8. Additionally in 46 patients, who were incapable for work in more than 6 weeks the year before rehabilitation, a reduction of 81 days off job was measured in the year after rehabilitation. DISCUSSION: The definition of aims of therapy is a mark of quality, and ES proves as a sensitive instrument of assessment, giving remarkable effects even one year after medical rehabilitation.

Female↗

Determination of an optimal forecast model for ambulance demand using goal programming.

A multistep approach to determining the optimal parameters of an exponential smoothing model was used to forecast emergency medical service (E.M.S.) demand for four counties of South Carolina. Daily emergency and routine (non-emergency) demand data were obtained and forecast statistics generated for each county sampled, using Winters' exponential smoothing model. A goal programme was formulated to combine forecast results for emergency calls with routine call forecasts. The goal programme gave a higher priority to accurate forecasting of emergency demand. The forecast model generated implicitly weights demand by severity and provides a reliable estimate of demand overall. The optimal parameter values for the smoothing model were obtained by minimizing the objective function value of the goal programming problem. The parameter values obtained were used to forecast demand for E.M.S. in the selected counties. The results of the model were compared to those using a multiple linear regression model and a single-objective-based exponential smoothing model for 2 months of data. When compared with two single-objective forecast models, the multiple-objective approach yielded more accurate forecasts and, therefore, was more cost-effective for the planner. The model presents and demonstrates a theoretical approach to improving the accuracy of ambulance demand forecasts. The possible impact of this approach on planning efficiency is discussed.

Ambulances↗

Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex.

Finding one's way in space requires a distributed neural network to support accurate spatial navigation. In the rat, this network likely includes the hippocampus and its place cells. Although such cells allow the organism to locate itself in the environment, an additional mechanism is required to specify the animal's goal. Here, we show that firing activity of neurons in medial prefrontal cortex (mPFC) reflects the motivational salience of places. We recorded mPFC neurons from rats performing a place navigation task, and found that a substantial proportion of cells in the prelimbic/infralimbic area had place fields. A much smaller proportion of cells with such properties was found in the dorsal anterior cingulate area. Furthermore, the distribution of place fields in prelimbic/infralimbic cells was not homogeneous: goal locations were overrepresented. Because such locations were spatially dissociated from rewards, we suggest that mPFC neurons might be responsible for encoding the rat's goals, a process necessary for path planning.

Action Potentials↗