Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “FIBROMA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,027 records · Page 57Linked to original sources

Perifollicular fibroma.

Perifollicular fibroma is a very unusual lesion and infrequently seen. The present report describes a thirty-two year old white man with unusual manifestations of this condition which usually presents as a small number of lesions on the head and neck, most often in adults. It has a characteristic pathologic picture of perifollicular fibrosis. The origin of this lesion is uncertain, but most probably represents a tumor of the connective tissue sheath of the follicle.

Adult↗

Strain differences in Shope fibroma virus. An immunopathologic study.

The pathogenic effects of plaque-purified Boerlage and Patuxent strains of Shope fibroma virus (SFV) in neonatal rabbits are compared with results of previous reports which used nonpurified SFV. Clinically, the Boerlage strain produced large tumors; whereas the same dose of Patuxent strain SFV induced much smaller tumors locally. Neither virus caused metastatic or extensively invasive local spread in our study. Some Patuxent recipients died of respiratory infections prior to sacrifice. However, both groups of rabbits handled the tumor well; the tumor began regressing 15-20 days after inoculation. Histologically, the tumors produced by those viruses were identical. Patuxent strain recipients were otherwise normal. Boerlage strain recipients showed increased persistence of extramedullary hematopoiesis and scattered foci of parenchymal necrosis in their livers. They also showed considerable cell death in thymic lobules. In rabbits given Patuxent strain SFV, virus antigens were detected only in the tumor by immunohistologic examination. Boerlage viral antigens were found in the tumor and overlying skin. We also detected virus systemically in Boerlage recipients: it was present in fixed tissue phagocytes in the spleen and liver and also in parenchymal cells of the lungs, liver, and kidney. Boerlage strain SFV recipients also showed detectable virus in their thymus, both at the periphery of the thymic lobules and in the connective tissue separating thymic lobules from each other. Despite the disseminated nature of the infection, rabbits that received the latter strain fared as well as those receiving Patuxent strain SFV.

Animals↗

[Osseous desmoid fibroma (2 case reports)].

Bone dermoid fibroma, described by Jaffe in 1958 is a benign fibroblastic tumour characterized by a remarkable tendency to expansion and to local recidives, without metastasizing. Some 38 cases have been reported to the present in the specialized literature. Two new cases are reported now, the first in the Romanian medical literature, one with localization of the tumour in the superior tibioperoneal metaphysis, and another located in the inferior femoral metaphysis. The first case recidivated after 3 surgical exereses over a period of nearly two years, and had to be amputated. The second case was solved by resection-arthrodesis of the Juvara-Merle d'Aubigne type, and is currently followed-up.

Adult↗

Tenosynovial fibroma.

Tenosynovial fibroma or angiofibroma of tendon sheath is a distinctive clinicopathological entity occurring mainly in young and middle-aged men and affecting dominantly the distal extremities. Fingers, hands and wrists are the site of 80 per cent of cases. Palmar aspects of hands and plantar aspects of foot are preferentially involved. The trunk and neck are seldom affected. They are generally small, firm, sometimes painful lesions attached to tendon sheath and/or tendon. The lesion must be distinguished from a variety of benign lesions including nodular fasciitis, angiomyoma and giant-cell tumour of tendon sheath. It can also be confused with sarcoma, including synovial sarcoma, because of the presence in it of characteristic slit-like spaces which have been identified as vascular rather than synovial spaces by virtue of the Factor VIII content of their lining cells.

Adult↗

[Right ventricular fibroma. Value of different methods of invasive and noninvasive exploration].

The authors report the case of a 20 year old man with a primary cardiac tumour. The relative usefulness of invasive (catheterisation and angiography), and non-invasive investigations (echocardiography, computerised axial tomography, myocardial scintigraphy and digitalised angiography) in determining operability and the benign or malignant nature of the tumour was evaluated. The patient was admitted to hospital for severe incapacitating effort dyspnoea. Cardiac auscultation was suggestive of pulmonary stenosis associated with tricuspid regurgitation. M mode and 2D echocardiography demonstrated a large mass within the right ventricular cavity and also its size shape, mobility and its relationship to the interventricular septum, tricuspid valve and the main pulmonary artery. Echo contrast studies confirmed tricuspid regurgitation and also demonstrated a patent foramen ovale. The cardiac CAT scan confirmed the preceding data. Myocardial scintigraphy demonstrated the vascular character of the tumour. Digitalised angiography showed the presence of a tumour in the right ventricle and the rest of the morphological information was identical to that obtained by conventional angiography. Cardiac catheterisation demonstrated an obstruction to right ventricular ejection and abnormal filling of both ventricles. It was the association of 2D echocardiography and Technetium 99 myocardial scintigraphy which provided the most information. The results of the other investigations were not essential in deciding the operative indications. A 230 g tumour was excised at surgery and the tricuspid valve replaced by a Hancock n 33 bioprosthesis. Anatomopathological examination showed the tumour to be a fibroma. The finding of a tricuspid diastolic rumble led to control catheter and angiographic studies 13 days after surgery.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Desmoplastic fibroma of the ulna. A case report.

This report of desmoplastic fibroma of bone (DFB) in the left ulna represents the 56th published case of the neoplasm. To the best of the authors' knowledge, the present case is the first instance of this type of excision of the distal ulna performed for DFB with a metallic prosthesis and successful restoration of distal radial ulnar anatomy and function.

Adult↗

[Juvenile aponeurotic (calcifying) fibroma].

A 10-year old boy suffered from a chondroid tumour in plantar part of the 3rd metatarsophalangeal joint. Alternating fibrous and chondroid structures were found by microscopy as well as collagen dystrophy with calcification. Giant cell reaction around connective tissue necrosis reminded of rheumatoid structure. Combined lesions described as characteristic for juvenile aponeurotic fibroma.

Calcinosis↗

[Fibroma of the ureter].

Fibrous polyps are very rarely found benign tumors of the ureter. Therapy should consist local resection of the tumor carrying part of the ureter with reestablishment of ureteral continuity. The diagnosis can be suspected from clinical signs, urography and retrograde pyelography. One own case of unusual morphology of ureteral fibroma is presented.

Adult↗

Successful surgical ablation of reentrant ventricular tachycardia caused by myocardial fibroma.

We successfully removed a fibroma of the left ventricle in a 13-year-old boy. The tumor had caused recurrent ventricular tachycardia, which was resistant to antiarrhythmic drugs. Preoperative and intraoperative electrophysiological studies led to a diagnosis of reentrant ventricular tachycardia. After surgical excision of the tumor, the ventricular tachycardia stopped completely and until now, 1 year after the operation, no antiarrhythmic drugs have been required.

Adolescent↗

[Giant fibroma of the pleura. Apropos of 2 cases].

Two cases are reported of giant pleural fibroma (2.9 and 4.2 kg), of slow growth (both had been present for 17 years), developing in the parietal pleura in a 56-year-old woman and in the triangular ligament of a 35-year-old man respectively, and treated by surgical excision. Findings in these cases and data on those reported in the literature indicate the principal pathologic and clinical characteristics of these very rare benign tumors of the pleura: onset in the absent of any history of exposure to dust (asbestos); usually fortuitous discovery; suggestive radiological appearances (calcification in some cases) that are not pathognomonic however; differentiation from fibrous mesothelioma by the microscopic or particularly gross pathologic appearance; treatment exclusively surgical and of variable difficulty according to the size of and especially the structures related to the tumor, with the need for careful preoperative screening.

Adult↗

[Trichoblastic fibroma].

A trichoblastic fibroma in the oval fossa of the left thigh of a 70 year old female is described. Basaloid cell complexes were surrounded by a moderately cellular, partly fibromyxoid stroma. Epithelial buds resembled the primitive hair germ which derives from the embryonal periderm. Epithelial layers, 1-2 cells thick, were enclosed in a hyalinized and condensed stroma. The development of a real hair bulb or a real hair matrix was not found.

Aged↗

[Clinical study of pleural fibromas].

After 3 personal observations of pleural fibromas, 67 analogous cases have been recorded. Clinical, radiological and pathological signs are recalled. The authors stress the 2 points which can turn this benign tumour into a serious disease :--onset of major hypoglycemia,--recurrences happening in a malignant fashion.

Adult↗

Successful excision of an intramural fibroma of the left ventricle.

A 2-year-old boy who presented with unrelated recurrent respiratory infections was found to have an enlarged cardiac silhouette on his chest roentgenogram. Clinical evaluation, echocardiography and cardiac cineangiograms failed to provide an accurate diagnosis. A left ventricular tumor was identified by exploratory thoracotomy and successful excision of an intramural fibroma of the left ventricle subsequently accomplished.

Child, Preschool↗

Desmoplastic fibroma of the mandible: report of case.

Desmoplastic fibroma of the bone is a rare tumor; only 48 cases of the disease have ever been reported. The tumor has most often been observed in the metaphysis of long bones. Nine cases of the lesion have been reported in the mandible. The lesion occurred in the left mandibular body of one of our patients. We treated the entity by surgically removing the tumor and concurrently reconstructing the jaw with a bone graft taken from the iliac crest. There has been no recurrence a year and eight months postoperatively.

Adult↗

Nonossifying fibroma. Electron microscopic examination of two cases supporting a histiocytic rather than a fibroblastic origin.

Nonossifying fibromas appear to be histiocytic lesions. On the basis of light and electron microscopic studies, as well as behavior, they are identical to benign fibrohistiocytomas found in soft tissues. The fibroblastic appearance of some of these lesions by light and electron microscopy, especially in older lesions, reflects the ability of histiocytes to behave as facultative fibroblasts. Final data of the cell of origin for these lesions must await more definitive studies by other methods, perhaps using immunologic, immunoperoxidase and/or surface markers techniques.

Adolescent↗