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At least 1,027 records · Page 57Linked to original sources
PubMed1978

Clinical course of adult metachromatic leukodystrophy presenting as schizophrenia. A report of two living cases in siblings.

Adult metachromatic leukodystrophy is a demyelinating disease due to an inherited lack of arylsulfatase A activity. The purpose of this paper is to present the characteristics of this disorder as they occurred chronologically in two siblings, prior to and subsequent to the appearance of gross neurological deficits. A deficit in spatial relationships, as contrasted with verbal abilities, was observed initially in both cases at age 13. Initial psychiatric symptoms were noted at age 16 and 18, with both patients being diagnosed subsequently as schizophrenic. Gross neurological deficits were observed 2 and 13 years, respectively, after the appearance of psychiatric symptoms. A deficit in spatial relationships may be a very sensitive early indicator of adult metachromatic leukodystrophy.

Adolescent↗
PubMed1986

Out-of-body experiences in schizophrenia. A questionnaire survey.

Questionnaires on perceptual distortions, symptoms of schizophrenia, and out-of-body experiences (OBEs) were completed by 71 volunteers with a history of schizophrenia and 40 control subjects (patients in a hospital accident ward). Significantly more of the schizophrenics (42%) than of the control group (13%) answered "yes" to a question about OBEs. However, a follow-up questionnaire showed that only 14% of schizophrenics (i.e., the same as the control group) had had "typical" OBEs, in which a change of viewpoint was reported. Those reporting typical OBEs did not report more perceptual distortions or symptoms of schizophrenia than did those reporting no OBEs, although those reporting other atypical experiences did. On this basis there is no evidence to consider the typical OBE as pathological or as symptomatic of schizophrenia.

Adult↗
PubMed1993

Culture, biology, and the near-death experience. A reappraisal.

Life review and tunnel sensation in near-death experiences appear to be culture-bound phenomena, confined largely to societies where historic religions are dominant. The clinical literature postulating biological theories for life review and tunnel sensations, therefore, may have been developed somewhat prematurely. The present review argues that social and historical explanations are more persuasive in the context of the available evidence presented here.

Humans↗
PubMed2004

Self creation and the limitless void of dissociation: the 'as if' personality.

The concept of the 'as if' personality has been used variously in analytic literature without having formed part of a clinically based theoretical development over time. The author discusses the bases of her notion of the 'as if' personality, as observed across a number of patients and supervised patients in intensive, long term analytic treatment. In this composite clinical picture, a grouping of elements that form a particular kind of defence of the self is identified in certain patients with an exceptional capacity for creative engagement in the world, surpassing expectations given their background. The picture includes the presence of physical breakdown and illness, as psychic suffering arising from early narcissistic wounding and from a physical, emotional and/or sexual abusive familial environment, was held for too long in bodily memory but not in mind. A distinction is made between the 'as if' personality, the persona and the false self. The 'as if' personality concerns the action of defensive dissociation deriving from very early experiences of internalizing the presence of an absent object, creating the sense of an internal void at the core of the self. At the same time, the self is capable of acts of self creation through a succession of identifications and internalizations with other sources of environmental nourishment, which substitute for, and are constructed around, the original sense of internal emptiness. Thus are restored, but only up to a point, the resources of the originally diminished self. Until these resources have been used up, the self is often able to excel in activities to an exceptional degree. The countertransference is shown to be the means of both useful but often perilously obtained clinical experience and information, supporting the work along the hazardous analytic journey.

Adult↗
PubMed1980

Windows in the intensive therapy unit.

Retrospective surveys were carried out on two groups of patients who had survived a stay of at least 48 h in an Intensive Therapy Unit. One group had been kept in a unit without windows, and the other in a similar unit with translucent but not transparent windows. Survivors from the windowless unit had a less accurate memory of the length of their stay, and were less well orientated in time during their stay. The incidence of hallucinations and delusions was more than twice as high in the windowless unit. The phenomenon of depersonalisation in the face of life-threatening danger is described and discussed.

Adult↗