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Breast cancer in previously burned skin: a postburn skin adnexal malignancy?

An unstable postburn scar at the submammarian fold 6.5 months after a burn injury turned out to be breast cancer. The unexpected histological findings and a possible correlation between the burn and the malignancy are discussed. This care report emphasizes the importance of histopathologic examination and the chance of unusual findings in a postburn ulcer.

Adenocarcinoma↗

Simple adnexal cysts in postmenopausal women: conservative management.

OBJECTIVE: To evaluate the expectant management of asymptomatic small, anechoic, simple ovarian cysts diagnosed by echography in postmenopausal women. To gain insight in the natural history of these cysts. METHOD: Thirty six postmenopausal women with asymptomatic ovarian cysts (from 1.5 to 5.0 cm) diagnosed by ultrasonography and with a CA 125 serum level within the normal range and a non-suspicious color Doppler were followed conservatively. Visits were scheduled at 8-10 weeks of the diagnosis, at 6-month intervals twice and annually thereafter. RESULTS: The follow-up period extended from 4 to 70 months with an average of 31.5 months. There were no cases of cyst enlargement. The cysts remained unchanged in 29 cases (80.5%), decreased in size in four cases (11.1%) and disappeared in three cases (8.3%). CONCLUSION: We think that the possibility of malignant transformation of one of these cysts is remote and the benefits of conservative management greatly outweighs its risks.

Adult↗

Tumors of the eye and ocular adnexal tissues.

This article reviews options in dealing with tumors of the cornea and conjunctiva, nictitating membrane neoplasms, and eyelid neoplasms. Orbital tumors, optic nerve and other intraocular tumors are also discussed.

Animals↗

Adnexal trauma.

Injuries to the adnexa have both functional and cosmetic implications. This article details the conditions, and their treatment, which ophthalmologists should be familiar with.

Eye Injuries↗

Laparoscopic management of 641 adnexal tumors in Kiel, Germany.

STUDY OBJECTIVE: To evaluate the effectiveness and safety of laparoscopic and laparotomic management of ovarian tumors. DESIGN: Retrospective analysis (Canadian Task Force classification II-2). SETTING: University-affiliated hospital. PATIENTS: Six hundred forty-one women with benign and malignant ovarian tumors. INTERVENTIONS: Laparoscopy and laparotomy. MEASUREMENTS AND MAIN RESULTS: Between January 1997 and December 1998, 493 (76.9%) ovarian tumors were treated laparoscopically and 138 (21.5%) by laparotomy. Criteria for laparotomy were high suspicion of malignancy and tumors larger than 10 cm that were technically too difficult for the laparoscopic approach. The mean size of tumors treated laparoscopically was 4.5 cm (range 1.1-11 cm) and by laparotomy 8.2 cm (range 3-20 cm). Mean operating times were 75.7 minutes (range 30-200 min) and 126 minutes (range 30-235 min), respectively, and mean blood loss was 193 ml (range 50-1200 ml) and 431 ml (range 50-2500 ml), respectively. Twelve laparoscopies were converted to laparotomy, six because of technical reasons such as severe adhesions, bleeding, or tumor size, and six for intraoperative suspicion of malignancy. Of the latter, four (66.7%) turned out to be ovarian carcinoma and two (33.3%) borderline tumors. Histologic evaluation clearly revealed predominance of functional ovarian cysts, endometriomas, and dermoid cysts in the group treated by laparoscopy, whereas ovarian carcinomas, large endometriomas, and serous cysts prevailed in the laparotomy group. CONCLUSION: With careful preoperative screening, the rate of laparoscopies for treatment of benign ovarian cysts can be increased. (J Am Assoc Gynecol Laparosc 8(1):74-82, 2001)

Adolescent↗

Correlation Between AFS Classification Systems of Adnexal Adhesions and Distal Tubal Occlusion, Tubal Mucosa at Salpingoscopy and Reproductive Outcome of the Patient

From November 1988 to December 1991, 45 infertile patients underwent salpingo-ovariolysis and/or salpingoneostomy during laparotomy or laparoscopy. Findings at surgery were scored according to the AFS classification. Salpingoscopy was performed to evaluate the status of the ampullary mucosa. The mean age of the patients was 29.5 years and the mean length of infertility prior to surgery was 4.4 years. All patients were contacted by phone to obtain information on reproductive outcome with a minimum period of 18 months of follow-up. Statistical analysis of data was performed using the Fisher's exact test. AFS scores were not correlated with reproductive outcome, while the status of the tubal mucosa at salpingoscopy was significantly correlated with reproductive outcome.

Journal Article↗

Laparoscopic Ligation of Large Adnexal Varices

A 14-year-old girl experienced severe incapacitating pelvic and abdominal pain. A large venous anomaly was noted at laparoscopy, performed in Saudi Arabia, corresponding to the patient's pain. Multiple endoloop laparoscopy ligations of the venous complex was performed. A follow-up laparoscopy 8 months later confirmed continued occlusion of the vascular complex. The patient continued to have satisfactory pain relief when examined 21 months postoperatively.

Journal Article↗

Papillary endothelial hyperplasia of adnexal vasculature.

Papillary endothelial hyperplasia is an exuberant predominantly intravascular endothelial proliferation which may simulate angiosarcoma both clinically and histopathologically. This report describes what, to the best of our knowledge, is a unique case of papillary endothelial hyperplasia within para-ovarian and paratubal veins in relation to a multicystic mesothelial and haemorrhagic ovarian mass. Papillary endothelial hyperplasia should be included in the differential diagnosis of vascular lesions in this site.

Adult↗

Early surgical intervention as definitive treatment for ocular adnexal capillary haemangioma.

BACKGROUND: Capillary haemangioma is the most common orbital and eyelid tumour of childhood, with a prevalence ranging from 1 to 3%. Periorbital haemangiomas can cause amblyopia secondary to anisometropia, induced astigmatism, strabismus or occlusion of the visual axis. Oral and intralesional steroids are considered to be the most accepted form of primary treatment. The authors have been performing early surgery as definitive treatment in selected lesions and believe it has an important role. METHODS: A retrospective chart review of 17 infants (2-20 months old) seen between 1996 and 2002 was carried out. Indications for surgery in the present series were astigmatism, rapid growth, anisometropic amblyopia and obscuration of the visual axis. Thirteen were treated primarily with surgery and the other four were treated with other methods prior to considering surgery. Preoperative computed tomography scans were obtained when indicated. RESULTS: Fourteen lesions were completely excised; residual tissue was deliberately left in order to preserve vital structures in three cases. No major surgical complications were noted. One child with residual tissue after surgery, who had proliferation of the remaining tissue, developed anisometropic amblyopia and ptosis. One child had a mild ptosis postoperatively that resolved after 6 months. Follow up was for an average 11.1 months. CONCLUSIONS: Early surgical intervention should be considered in a multidisciplinary team approach as a primary treatment option with selected, isolated haemangiomas, without a significant cutaneous component. Surgery is a safe, effective treatment for selected lesions, provides a definitive early treatment, and prevents astigmatism and occlusion-related amblyopia.

Amblyopia↗

Validity of pulsatility and resistance indices in classification of adnexal tumors with transvaginal color Doppler ultrasound.

Transvaginal pulsed color Doppler ultrasound was used to examine 72 patients with a pelvic mass preoperatively. Tumor morphology was assessed, prominent areas of vascularization within the tumor were observed and the pulsatility index and the resistance index of tumor and uterine arteries were measured. Flow velocity waveforms with low pulsatility are considered to reflect neovascularization. The ultrasound diagnoses were compared with histopathological or cytological diagnoses. There were 61 benign, eight malignant and three borderline cases. In 75% of the malignant and 23% of the benign tumors, an intratumoral flow with a low pulsatility was detectable. The mean pulsatility index of tumor blood vessels was 1.2 in benign, 0.7 in malignant and 0.6 in borderline neoplasms. The corresponding mean resistance index values were 0.6, 0.5 and 0.5. The differences were not significant and the overlap between the malignant and benign lesions was large. The pulsatility index and resistance index of uterine arteries were significantly decreased in malignant tumors. The results show that, using a cut-off resistance index value of 0.6, the sensitivity and specificity of color Doppler in the detection of malignant and potentially malignant tumors were 82% and 72%, respectively. However, a practical cut-off level for either pulsatility or resistance indices, that could assist in differentiating between malignant or benign lesions, does not seem to exist.

Journal Article↗