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Type 1 diabetes mellitus and oral health: assessment of periodontal disease.

BACKGROUND: The periodontal disease status of 320 dentate adults, diagnosed 23.7 years previously with Type 1 insulin dependent diabetes mellitus, was evaluated. These patients had been monitored at 2-year intervals as part of a large University of Pittsburgh longitudinal study assessing the medical complications associated with insulin dependent diabetes. METHODS: During one of their regularly scheduled medical examinations, a group of 320 adult dentate subjects (mean age of 32.1 years) received a periodontal examination as part of a comprehensive oral health assessment. The oral health assessment collected data regarding demographics, oral health behaviors, tooth loss, coronal and root caries, salivary functions, and soft tissue pathologies. For the periodontal assessments, 3 facial sites (mesial, midcervical, distal) of the teeth in the right maxillary/left mandibular or left maxillary/right mandibular quadrants were evaluated for calculus, bleeding on probing (BOP) and loss of gingival attachment (LOA). RESULTS: Attachment loss was significantly greater for older patients whereas BOP and calculus levels were relatively constant across age categories. Univariate analyses of factors possibly related to extensive periodontal disease (LOA > or =4 mm for at least 10% of sites examined) indicated an association with older age; lower income and education; past and current cigarette smoking; infrequent visits to the dentist; tooth brushing less than once per day; older age of onset; longer duration of diabetes; and the diabetic complication of neuropathy. A multivariate regression model of all possibly significant factors found current cigarette use (odds ratio [OR] = 9.73), insulin dependent diabetes onset after 8.4 years of age (OR = 3.36), and age greater than 32 years (OR = 3.00) explained the majority of the extensive periodontal disease in this group of diabetic patients. CONCLUSIONS: Management and prevention of extensive periodontal disease for Type 1 diabetic patients should include strong recommendations to discontinue cigarette smoking.

Adult↗

An overview of periodontal surgical procedures.

It is obvious from the foregoing that there are many technical approaches to periodontal surgery. The mere presence of a periodontal pocket of a cerain depth as the major indicator for surgery is not as steadfast as once believed. Other criteria such as hemorrhage and exudate must also be used in evaluating the need for surgery. The decision on which approach to use remains with the therapist and the individual situation which he/she is faced. However, in the past decade it has become increasingly clear that the need for so-called more advanced surgical procedures is not as important to the control of periodontal diseases as was once thought. Regardless, it is also clear that some form of surgical intervention, as defined by this paper, is still necessary to interrupt the sequence of events that make up the pathogenesis of periodontal disease that leads to eventual tooth loss. This paper has reviewed and evaluated some of the current procedures available to the therapist in the surgical approach to therapy.

Alveoloplasty↗

Trauma to the oral cavity.

Sports events, particularly those in which mouth protectors are not commonly used, can be associated with injuries to the oral structures. While the incidence of sports-related orofacial injuries is not as high as for other traumatic events, the incidence could be reduced further by increased use of mouth and face protection. When injuries occur, quick action by primary health care providers can significantly improve the final outcome of the definitive treatment. Also important is appropriate follow-up evaluation and care since the effect of trauma on teeth is not always immediately apparent. Destructive resorption, unnecessary tooth loss, and possible alveolar infections may be prevented by referral to appropriate health care providers for evaluation following the initial urgent care of trauma patients.

Athletic Injuries↗

A long-term followup on the retention rate of zinc oxide eugenol filler after primary tooth pulpectomy.

A retrospective study of all the patients' records (> 6000) in a pediatric dental practice was done to assess ZOE retention after a pulpectomized primary tooth was lost and the succedaneous tooth erupted. There were 65 children with 81 ZOE pulpectomies done in 30 incisors and 51 molars. Pulpectomies were done at a mean chronologic age of 52.2 months and followed for a mean time of 90.8 months from time of placement. The initial radiograph after the pulpectomized tooth was lost, showed retained ZOE filler particles in 49.4% of the cases while 27.3% had retained ZOE a mean time of 40.2 months after pulpectomy tooth loss. Short-filled pulpectomies retained significantly less ZOE than long fills (P = 0.04). With time, retained ZOE particles either resorbed completely or showed reduction of filler size in 80% of the cases. No pathology was associated with the retained ZOE particles. Retention of ZOE was not related to pulpectomy success (P = 0.11), preoperative root resorption (P = 0.76), age of the patient (P = 0.24 incisors; P = 0.87 molars), extraction/exfoliation of the pulpectomy (P = 0.75), or timing of the pulpectomy's loss (P = 0.72).

Age Factors↗

Periodontal disease in ancient populations.

Recent clinical and anthropological findings indicate that the conventional concept of the pathogenesis of periodontal disease requires review. The periodontal lesion has been defined as a generalised horizontal loss of crestal bone resulting from host immune and inflammatory responses triggered by the action of commensal bacteria, and the extension of gingivitis into the deeper periodontium to become periodontitis has been assumed to occur slowly but steadily over many years. Anthropological and clinical investigations reveal that the widespread loss of crestal tissue is relatively unusual and that lesions of the alveolus are commonly localised and severe. Longitudinal studies have shown that the disease progresses in bursts and is stable in both the gingivitis and periodontal modes in between the burst activity. The findings of the present study demonstrate that generalized horizontal periodontitis has been unusual and has not been responsible for tooth loss. Other factors responsible for deficient alveolar margins in dry bones have been overlooked in most studies, leading to overassessment of the incidence of periodontal disease in postmortem materials; the same assumptions have led to overassessment of periodontal disease in clinical studies and practice.

Anthropology, Physical↗

Effect of periodontal therapy on patients maintained for 15 years or longer. A retrospective study.

A retrospective study of tooth loss in 211 patients who were treated for periodontal disease in private practice and maintained for 15 to 34 years on 3- to 6-month recall schedules is reported. The average age of the patients was 42 years, and the average length of time in maintenance was 22 years. On the basis of response to therapy, the patients were classified as Well-Maintained (62%), Downhill (28%) and Extreme Downhill (10%). Seven hundred and seventy-one (771) teeth were lost (13.4%) due to all causes. Molar teeth are the most prone to loss and the mandibular cuspid is the most resistant. The importance of maintenance therapy is emphasized.

Adolescent↗

Oral and maxillofacial surgical therapy for the older adult.

Older adults can present with a wide range of oral and maxillofacial diseases and conditions, and many of these are best treated surgically. One of the distinguishing features of geriatric surgery is the large percentage of older adults who have medical conditions that must be planned for perioperatively. Good communication between the surgeon and the primary care physician is important for this perioperative management. Orofacial infections, the most common of which are odontogenic in origin, require some form of surgical treatment and may or may not require treatment with antibiotics. Preprosthetic and reconstructive surgery may be necessary to treat the sequelae of oral and maxillofacial fractures, the sequelae of tooth loss, or surgical defects incurred during the treatment of cancer, osteomyelitis, osteoradionecrosis, or disorders of the TMJ.

Aged↗

[Periodontal disease and prevention in children and adolescents].

Clinical and epidemiological studies have shown that: 1. Bacterial plaque which accumulates around the teeth is responsible for chronic periodontal inflammation. From adolescence on, this inflammation is almost universal. 2. Gingivitis prepares the periodontitis, which is characterized by a migration of the epithelial attachment, pocket formation and progressive bone loss. 3. Calculus is formed by plaque calcification. Its rough surface allows bacterial retention and proliferation in contact with the epithelial covering. 4. The mechanisms of host resistance to parasitic plaque are mostly unknown. This resistance is variable and seems to decrease with age. 5. Periodontal disease in children and adolescents is a real problem in preventive medicine, because of its immediate or remote consequences on tooth loss. Thanks to fluoride, the prevention of dental caries is quite effective; the prevention of periodontal disease is on the contrary much more difficult. Mechanical removal of plaque is tedious and must be done again and again; however, it is not logical to separate prevention of caries from that of periodontal disease. Information of the public at large on oral health is of utmost importance, as well as a good cooperation of the teachers in preventive programs for schoolchildren. Every health department or service should try to apply the following measures: -Permanent employments for "school dental nurses" should be created, on a part-time or full-time basis. They should take care of the organisation and supervision of oral health programs. -In each school dental service, a dentist should be responsible for teaching the theoretical and practical aspects of periodontal prevention. -Caries reduction obtained by fluorides is no excuse to reduce the "treatment staff". This staff should be devoted to prevention at large and to refreshing courses. In a young population with regular supervision, prevention of periodontal disease can meet with considerable success. Initial periodontal disease is reversible: it is possible to avoid the degradation of gingivitis in progressive periodontitis, and this helps maintaining dental and periodontal health throughout life.

Adolescent↗

Dental paleopathology in a Serbian Medieval population.

Analysis of the pattern of dental disease in two Late Medieval populations from cemeteries excavated at archaeological sites in western Serbia was based on the study of tooth wear, ante-mortem tooth loss, caries, dental enamel hypoplasia, alveolar resorption, abscesses and calculus. The findings reported here show a high prevalence of attrition, alveolar resorption and caries, which suggest an abrasive diet and poor oral hygiene.

Adult↗

Trauma to primary teeth of South African pre-school children.

A clinical survey of 1466 children of typical South African communities showed a prevalence rate of primary tooth trauma of 15%. Trauma was least common at age 1-2 years (10.7%) and most common at 4-5 years (20.6%). The commonest trauma seen was fracture of enamel only (71.8%) followed by fracture of dentine (11.2%), tooth loss (8.2%) and discolouration without other sign of injury (5.6%).

Age Distribution↗

Self-reported and clinical oral health in users of VA health care.

BACKGROUND: This article describes the oral health of users of Veterans Administration (VA) health care using both clinical and self-report measures, and models relationships between these measures and self-perceived oral health. METHODS: We conducted a cross-sectional study of 538 male users of VA outpatient care in the Boston area. Questionnaires assessed self-reported oral health, oral-specific health-related quality of life, health behaviors, and sociodemographic information. Clinical data were collected on oral mucosa status, number of teeth and root tips, dental caries, and periodontal treatment need. We report clinical and self-reported oral health status by age group (era of military service). We regressed models of self-perceived oral health on clinical indices and self-reported measures of the impact of oral health on daily life, adjusting for sociodemographic characteristics and health behavior. RESULTS: Among those participants aged 65 to 91 years old, 2.8%, 18.7%, and 41.5% rated their oral health as excellent, very good, or good, respectively. Among 50- to 64-year-old men, the corresponding values were 1.4%, 18.5%, and 40.4%, while among those aged 22 to 49 years old, the values were 2.3%, 17%, and 34.1%. Tooth loss was common among users of VA care; 34% of those aged 65-90 years, 28% of those aged 50-64 years, and 8% of those aged 25-49 years had no teeth. Periodontal treatment needs were uniformly high among persons with teeth; mild mucosal change was common, and 10% had root tips. Regression models showed self-perceived oral health was better in persons with more teeth and recent dental treatment, and worse with tooth mobility, coronal decay, and more medical problems. Measures of the impact of oral conditions on daily life added significantly to the amount of explained variance in self-perceived oral health. CONCLUSIONS: Clinical conditions and the impact of oral health on daily life are important determinants of self-perceived oral health.

Adult↗

Tooth survival in institutionalized elderly Cape Coloreds from the Cape Peninsula of South Africa.

An investigation has been conducted in order to assess the oral health status and need for dental treatment among Cape Coloreds resident in homes for the aged in the Cape Peninsula of South Africa. Tooth loss was greater in females than in males (P less than 0.002) but a statistically significantly greater proportion of surviving teeth were grossly carious in men than in women (P less than 0.002). More teeth had survived in the mandible than in the maxilla (P less than 0.002) and proportionately more teeth were grossly carious in the maxilla than in the mandible (P less than 0.002). The distribution pattern of the remaining dentition according to tooth type was similar for both jaws, the canines being the most persistent teeth.

Aged↗

Reasons for extraction of permanent teeth in Japan.

Eight hundred forty-nine Japanese dentists were asked to record the reason for every tooth extraction of permanent teeth during 1 week in each of four seasons. The reasons were assigned to six groups: dental caries, periodontal disease, eruption problems, trauma, orthodontics and other reasons. Thirty-eight to 40% of the dentists returned the forms in each season, relating to a total of 11,175 extracted teeth. Overall, caries was the most frequent reason for tooth extraction (55.4%), followed by periodontal disease (38.0%). The females lost more teeth due to caries than did the males. In the > or = 16 age groups, caries was the main reason for tooth extraction. However, periodontal disease became principal only in the males aged 46-65 yr. Anterior teeth, especially in the mandible, represented the highest percentage of periodontal extractions. A considerable difference in the major reason for maxillary tooth loss was observed between both sexes. Maxillary premolars and molars in the males were extracted for periodontal disease as much as for caries, whereas caries was the predominant reason for loss of all maxillary teeth in the females.

Adolescent↗

Tobacco smoking: a major risk factor for loss of teeth in three 70-year-old cohorts.

Oral health was examined in a random sample of 1377 people in three 70-year-old cohorts studied within 5-yr intervals. During the studied period 1971-1983 the prevalence of toothlessness decreased from 52 to 34%. Toothlessness in men was more common in smokers, 48%, and ex-smokers, 32%, than in non-smokers, 20%. Eichner's index was used as a measurement of dental invalidity. This index showed a worse dental state among smokers and ex-smokers compared to non-smokers. Multivariate analyses indicated that tobacco smoking was a major independent risk factor for tooth loss in elderly men.

Age Factors↗

Revascularization of traumatized teeth assessed by laser Doppler flowmetry: case report.

Infection of the pulp space in addition to the attachment damage of a traumatic injury to a tooth, results in serious complications and often tooth loss. Therefore, the prevention or treatment of root canal infection is a major consideration in these cases. In immature teeth, revascularization of a necrotic pulp is possible and highly desirable. Unfortunately, current sensitivity tests are poor indicators of revascularization, with the result that many pulps are removed unnecessarily. Laser Doppler flowmetry is an objective test of the presence of moving red blood cells within a tissue, which has been reported to be effective in the detection of tooth pulp vitality as well. A case is presented where an eight year old child severely luxated both maxillary central incisors. While only one of the incisors was weakly responsive to CO2 ice at 76 days after replantation, the laser Doppler flowmeter indicated that revascularization was occurring in both teeth at a much earlier time. Because of the laser Doppler readings, endodontic treatment was not initiated and the teeth developed normally.

Child↗

Heritable disorders of the RANKL/OPG/RANK signaling pathway.

Figure 7 summarizes the heritable disorders identified to date that directly involve the RANKL/OPG/RANK signaling pathway in humans. Activating mutations in TNFRSF11A encoding RANK and deactivating mutations in TNFRSF11B encoding OPG cause systemic bone disease (FEO, PDB2, ESH and JPD) featuring accelerated bone turnover, low bone mass, deafness early in life, and loss of dentition by enhancing signaling. No human disease has been identified involving defects in the TNFSF11 gene encoding RANKL. Despite genetic bases for these autosomal dominant and recessive conditions involving bone cell receptors, focal expansile osteolytic lesions are common and can occur perhaps from further local activation of osteoclast-mediated bone resorption following trauma. These disorders resemble PDB which can be inherited as an autosomal dominant trait with focal osteolytic disease, sometimes with deafness and tooth loss, and increasingly associated with mutations, but in other genes.

Bone Diseases, Metabolic↗

Socioeconomic inequalities in oral health in childhood and adulthood in a birth cohort.

OBJECTIVES: To determine whether adult oral health is predicted by (a) childhood socioeconomic advantage or disadvantage (controlling for childhood oral health), or (b) oral health in childhood (controlling for childhood socioeconomic advantage or disadvantage), and whether oral health in adulthood is affected by changes in socioeconomic status (SES). METHODS: Participants in a longstanding cohort study underwent systematic dental examination for dental caries and tooth loss at ages 5 and 26 years. The examination at age 26 years included the collection of data on periodontal attachment loss and plaque level. Childhood SES was determined using parental occupation, and adult SES was determined from each study member's occupation at age 26 years. Regression models were used to test the study hypotheses. RESULTS: Complete data were available for 789 individuals (47.4% female). After controlling for childhood oral health, those who were of low SES at age 5 years had substantially greater mean DFS and DS scores by age 26 years, were more likely to have lost a tooth in adulthood because of caries, and had greater prevalence and extent of periodontitis. A largely similar pattern was observed (after controlling for childhood SES) among those with greater caries experience at age 5 years. For almost all oral health indicators examined, a clear gradient was observed of greater disease at age 26 years across socioeconomic trajectory groups, in the following order of ascending disease severity and prevalence: 'high-high', 'low-high' (upwardly mobile), 'high-low' (downwardly mobile) and 'low-low'. CONCLUSION: Adult oral health is predicted by not only childhood socioeconomic advantage or disadvantage, but also by oral health in childhood. Changes in socioeconomic advantage or disadvantage are associated with differing levels of oral health in adulthood. The life-course approach appears to be a useful paradigm for understanding oral health disparities.

Adult↗

Levator labii superioris muscle transposition to treat oromaxillary sinus fistula in three horses.

OBJECTIVE: To describe surgical transposition of the levator labii superioris muscle to treat oromaxillary sinus fistula in horses. STUDY DESIGN: Clinical study. ANIMALS: Three horses with chronic oromaxillary sinus fistula. METHODS: After severing its tendinous insertion, the muscle belly of the levator labii superioris muscle was retracted and transposed through the oromaxillary sinus fistula. The tendon exited the oral cavity through a full-thickness buccal incision created adjacent to the oral end of the fistula and was then tunneled subcutaneously in a ventral direction before being anchored by sutures to the cheek tissues. RESULTS: Fistulae healed with few complications and with good cosmetic and functional results. CONCLUSIONS: Oromaxillary sinus fistula associated with molariform tooth loss in horses can be treated successfully by transposition of the levator labii superioris muscle. CLINICAL RELEVANCE: Transposition of the levator labii superioris muscle should be considered for resolution of chronic oromaxillary sinus fistula in horses.

Animals↗