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[Murine typhus].

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Animals↗

[Epidemic typhus].

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Anti-Bacterial Agents↗

Sero-epidemiological survey of scrub typhus.

A total of 1017 human sera from ecologically different areas in the states of Rajasthan and Jammu & Kashmir were subjected to the CF test using the Gilliam strain antigen of R. tsutsugamushi. Results revealed that 2.4% and 3.5% of the populations examined in the two states respectively, were found to possess antibodies to the test antigen. The titres of positive sera varied from 1:8 to 1:32. Findings of this survey could be correlated with the local topography, presence or absence of vector and the exposure of susceptible population to the rickettsial agent. However, the presence of hidden foci in the neighbouring areas not covered by the current survey cannot be ruled out.

Antibodies, Bacterial↗

[A histologic study of Ceratophyllus consimilis Wagn. fleas infected by the agent of murine typhus (Salmonella typhimurium)].

Histological studies of C. consimilis infected with S. typhimurium have shown that the microbes are preserves along the whole extent of the alimentary canal, expecially in the midgut and pyloric portion. Bacteria are concentrated in the gastral cavity; in addition, they were found to penetrate the alimentary epithelium cells and pyloric valve tissue. The number of microbes and their distribution in the intestine undergo great variations that depends largely on the insects feeding rhythm. During bloodsucking a "lavenment" of the alimantary canal takes place; as a result, numerous microbes accumulated here are periodically excreted outside. The infection with Salmonella typhimurium is often accompanied by pathological changes in fleas tht is expressed in the destruction of the midgut epithelium and pyloric valve tissue.

Animals↗