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PubMed1975

[Prognosis of pathologic personality changes, repeated hospitalizations and assessment of the risk of suicide attempts in reactive depression].

With the aid of clinical scales and eventual components, regressive and discriminant analysis the author elaborated a system of prognostical indices for the assessment of unfavourable outcomes and formation of pathological personality development as well as in patients with reactive conditions in the form of depressions, neurasthenia and hysterical neurosis. Observations which amounted to the mark equal to or exceeding the critical (68) should be considered as dangerous in relation to a formation of a pathological personality.

Adjustment Disorders↗
PubMed1983

Family structure and dynamics in DePalma's horror films.

An analysis of the familial relationships in Brian DePalma's five major horror films reveals a persistent unconscious fantasy formation involving the nuclear family. These single-parent, only-child families are all tragically destroyed because of an inability to adequately mourn the absent parent. Although the asexual young adults in the films are spared the completely disastrous effects of madness and violence, they are still psychologically traumatized. This hidden subtextual theme involving the family parallels DePalma's bleak view of authority figures outside the home, as well as American society in general. Adequate identity formation requires that people both inside and outside the family accept the adolescent as a separate person. The grim psychological truth threading its way throughout DePalma's horror films is that these young adults are psychically devastated by the effects of a primitive, fused symbiotic relationship in interaction with a society that does not provide an adequate role for the developing person. Consequently, their attempt to psychologically move outside the family, which includes the maturation of their sexuality, results in the destruction of the family itself.

Family↗
PubMed1993

IgA as a marker of clinical progression among HIV-seropositive intravenous drug users.

The recognition of markers of progression towards disease in carriers of HIV is important in order to identify those who will develop AIDS and to start antiviral treatment at the appropriate time. Most studies of potential markers of progression have been made on homosexual men and haemophiliacs. We studied a population of 87 intravenous drug users (IVDUs), recruited between May 1984 and May 1986, in order to determine the usefulness of CD4 and CD8 counts as well as IgG, IgM and IgA values in predicting progression to AIDS. Eight persons developed AIDS during a median period of 44 months. Overall, the mean IgA value was lower in HIV-seropositive IVDUs than in HIV-negative IVDUs and in HIV-negative persons not using IV drugs and who acted as controls. Even so, a concentration of IgA > 2.5 g/l at enrollment was the best predictor of progression to AIDS. This finding suggests that a raised concentration of IgA may be an important early marker of progression towards disease in this population.

Acquired Immunodeficiency Syndrome↗
PubMed1981

Mildly handicapped children in the mainstream--implications for the health educator.

The Education for All Handicapped Children Act of 1975, PL 94-142, will cause mildly handicapped children to be integrated into mainstream academic classes including health education. Because of the disparate needs of these children, health educators will have to provide for a diverse group of learners. Since it is clear that health education encompasses topics crucial to the overall social and personal development of the handicapped, it is essential that health educators become prepared to maximize learning opportunities for the handicapped child in the mainstream.

Child↗
PubMed1979

Screening and selecting candidates for a hospital pharmacy residency program.

An applicant screening and selection procedure for a hospital pharmacy residency program which (1) efficiently processes a large number of applicants while minimizing the subjective nature of the review process and (2) ranks candidates for submission to the ASHP Residency Matching Program is described. A screening and selection committee consisting of five staff members of the hospital pharmacy department was created. Goals of the residency program and qualities of the optimal resident were defined prior to development of the screening and selection program. Two forms were used by staff in the screening process: a screening worksheet for the preinterview screen, and an evaluation chart for the interview phase. Each form outlined the criteria which serve as indicators of academic, professional and personal development in a format that allows easy extraction of data. By carefully defining program goals and identifying specific human qualities most compatible with those goals, the likelihood of successful applicant selection through use of a systematic screening process is increased.

Education, Pharmacy, Graduate↗
PubMed1994

A psychoanalyst looks at a hypnotist: a study of folie à deux.

This paper traces my personal development from anesthetist to hypnotist, psychotherapist, and, finally, psychoanalyst. The change was precipitated by the successful treatment of a patient with congenital organic skin disease by hypnotism. Alongside my change of profession, I attempt to illustrate my change of ideas and the change of my relationship to patients which accompanies these other changes. I feel that my personal experience throws some light on the nature of suggestion and hypnotism and how they differ from each other and from psychoanalysis. I believe that observations support the idea that hypnotism is a folie à deux caused by mutual projective identification between two people and that in a less dramatic form this condition commonly occurs in normal development as well as in pathological psychological states. Several cases illustrate these ideas.

Adult↗
PubMed2004

Diseases of modern living: neurological changes associated with mobile phones and radiofrequency radiation in humans.

Health effects of radiofrequency radiations (RFR) including mobile phone technology and the adequacy of their safety standards remain uncertain. Case reports of peripheral neurological effects of RFR describe mainly disturbances of noxious sensation (dysaesthesia). Cases associated with other RFR sources as well as mobile phone technology are examined seeking insights into neurophysiological mechanisms and safety levels. Cases have arisen after exposure to much of the frequency range (low MHz to GHz). In some instances symptoms are transitory, but may be lasting in others. After very high intensity exposures nerves may be grossly injured. However, after lower intensity exposures which may result in dysaesthesia, ordinary nerve conduction studies demonstrate no abnormality although current perception threshold studies may. Only a small proportion of similarly exposed persons develop symptoms. The role of modulations (e.g. pulses) needs clarification. Some of these observations are not consistent with the prevailing hypothesis that all health effects of RFR arise from thermal mechanisms. It is concluded that RFR from mobile phones can cause peripheral neurophysiological changes in some persons. The effects occur at exposure levels below the present safety levels for RFR. Possible non-thermal mechanisms are discussed and may point to future directions of research.

Cell Phone↗
PubMed1999

Primary central nervous system lymphoma: from clinical presentation to diagnosis.

Immunocompetent patients with primary central nervous system lymphoma (PCNSL) present with a median age of 55 years, immunosuppressed patients with a median age of 40 years. They show a broad range of signs and symptoms. Symptoms of increased intracranial pressure and personality change are most frequent, followed in frequency by ataxia and hemiparesis. The median time from onset of symptoms to diagnosis is 3-5 months in immunocompetent patients and 2 months in immunodeficient patients. The time to diagnosis can be considerably longer in patients with slowly developing personality change or fluctuating symptoms due to spontaneous or steroid-induced remission of so-called sentinel lesions. Native CT scans show iso- or hyperdense lesions with homogenous contrast enhancement. T1-weighted MRI scans show hypointense and T2-weighted scans hyperintense lesions. The definitive diagnosis of PCNSL requires biopsy. In some cases, however, the definitive diagnosis may exclusively be made by the demonstration of malignant B-lymphocytes in the cerebrospinal fluid.

Adult↗
PubMedDate not supplied

Lateral crus sculpturing in open rhinoplasty: the Delicate Alar Clamp.

The wide exposition obtained with the open approach in rhinoplasty allows a precise evaluation of size, morphology, thickness, and position of the alar cartilages. This precise intraoperative diagnosis has permitted the development and improvement of surgical techniques in nasal tip sculpturing. At the same time, many surgical instruments have been adapted or created for the external approach. We describe our preferred and most commonly selected sequence in primary rhinoplasty with emphasis on the nasal tip work. A new, personally developed instrument, named the Delicate Alar Clamp, utilized to hold and stabilize the lateral crus during measurement and sculpturing of the cartilage, is presented with the description of its technical characteristics and practical application.

Humans↗
PubMed2003

Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11.

OBJECTIVE: To estimate the potential public health impact of the findings of the Age-Related Eye Disease Study (AREDS) on reducing the number of persons developing advanced age-related macular degeneration (AMD) during the next 5 years in the United States. METHODS: The AREDS clinical trial provides estimates of AMD progression rates and of reduction in risk of developing advanced AMD when a high-dose nutritional supplement of antioxidants and zinc is used. These results are applied to estimates of the US population at risk, to estimate the number of people who would potentially avoid advanced AMD during 5 years if those at risk were to take a supplement such as that used in AREDS. RESULTS: An estimated 8 million persons at least 55 years old in the United States have monocular or binocular intermediate AMD or monocular advanced AMD. They are considered to be at high risk for advanced AMD and are those for whom the AREDS formulation should be considered. Of these people, 1.3 million would develop advanced AMD if no treatment were given to reduce their risk. If all of these people at risk received supplements such as those used in AREDS, more than 300,000 (95% confidence interval, 158,000-487,000) of them would avoid advanced AMD and any associated vision loss during the next 5 years. CONCLUSION: If people at high risk for advanced AMD received supplements such as those suggested by AREDS results, the potential impact on public health in the United States would be considerable during the next 5 years.

Antioxidants↗
PubMed1993

Introduction to special section: theoretical developments in the cognitive psychotherapies.

The cognitive psychotherapies have developed and substantially differentiated since their inception in the 1950s. Six major themes in their theoretical development are discussed: (a) the differentiation of rationalist and constructivist therapies and metatheories of knowing; (b) the acknowledgement of social, biological, and embodiment processes in therapy; (c) the recognition of unconscious processes; (d) an increasing focus on self-organizing and self-protective processes in life span personality development, with such processes being embedded in interpersonal and social system dynamics; (e) a shift toward different views of emotionality and the incorporation of experiential techniques; and (f) a synergistic involvement in the psychotherapy integration movement. The cognitive psychotherapies reflect remarkable activity, a point illustrated and elaborated in the articles that constitute this special section.

Adaptation, Psychological↗
PubMed1997

Psychosocial correlates of psychopathology in a national sample of the morbidly obese.

BACKGROUND: Although several studies have documented the existence of psychopathology in the morbidly obese, there is disagreement as to its extent and nature. The disagreement has been difficult to resolve because earlier studies have tended to use small, regional samples, and diverse, unstandardized approaches to measuring psychopathology. METHODS: To add clarity, the present study utilized an unusually large, national sample, all subjects of which were administered a standardized, comprehensive test of psychopathology (the MMPI-2), an intensive interview concerning psychosocial history, and a medical examination. Subjects' scores on the MMPI-2 were compared to available norms. The psychosocial interview yielded information about families of both origin and reference. Information about comorbidities, medications, and body mass index (BMI) were available from the medical examinations. Multiple regression analyses were performed to determine the variables that best predicted psychopathology and BMI. RESULTS: The percentage of subjects whose MMPI-2 scores exceeded and approached psychopathological levels was in excess of normative expectations. The 1,3,2 pattern of scale scores on this test expresses depressive disorder, with anxiety and somatization features. Regression analyses showed that abuse of the subject and of substances in the family of origin positively predicted, while education and number of children negatively predicted both psychopathology and BMI. CONCLUSIONS: Dysfunctionality in the family of origin may lead to obesity through such regressive coping styles as stress eating, but this can be offset by personal development and nurturance responsibilities.

Adaptation, Psychological↗
PubMed1978

[Psychological aspects of glossodynia (author's transl)].

The term glossodynia refers to all conditions with pain and dysaesthesia of the tongue and entire oral mucosa manifesting themselves in burning, prickling, itching, stinging, and other frequently bizarre sensations as well as subjective xerostomia and bad taste. In most cases psychiatric diseases are the cause of the complex of complaints whereas local and general disorders are of only minor importance. Menopausal women with atypical depression are most often affected. Schizophrenia and abnormal personality development are far less frequent in glossodynia. After exclusion or therapy of organic disorders antidepressants are the treatment of choice in glossodynia. Thereapeutic difficulties may arise in patients suffering from marked xerostomia whose complaints may intensify during therapy because of the anticholinergic effect of most antidepressants, and in neurotic persons.

Adult↗
PubMed1987

Characteristics and functions of community health workers in Saradidi, Kenya.

A community-based health development programme in Saradidi, Kenya had 126 village health helpers (VHH's) for the 56 villages. These volunteer health workers lived in the community and served a total population of about 43,000 in an area of 225 km2. Each VHH served a maximum of 100 households averaging 4.0 persons. Conditions imposed by the community were that the VHH be perceived to be a mature person, to be compassionate and to have a desire to help people and to live in the village. Literacy or formal education were not requirements. VHH's were chosen and supported by the people who lived in their village. Characteristics of the 126 VHH's were that 96.8% were women, 99.2% were married, 75.4% were between 25 and 39 years of age, and 80.2% had at least five years of formal education (only 7.1% had none). The VHH's spent an average five to ten days each month on programme activities in addition to their other responsibilities which included preparing meals, cleaning their homes, carrying water and firewood from long distances, caring for their children and cultivating food for their family. Each VHH visited about 15 households per month, spending one to two hours on a visit. Problems experienced by a random sample of 36 VHH's included difficulties due to lack of transport, lack of medicines, slowness of the community to accept new ideas, distance from project clinic, lack of food in the village, weak village health committees, and no payment for services. The main support for the VHH's came from village women individually, women's groups, and the central programme committee. Village Health Committees did not provide effective support. Nevertheless, in four years only four of the 126 VHH's dropped out of the programme. The main reasons that 36 VHH's reported for continuing to volunteer were as follows: the continuous training they were given was beneficial (mentioned by all); they agreed to serve the villages and did not want to go back on their word (36.1%); they liked the work (19.4%); they felt they have an impact on the health of people in the village (16.7%); the allowances they sometimes receive (22.2%); and personal development (13.9%). The characteristics and responsibilities of community health workers in Saradidi were similar to those elsewhere. The ingredients for a successful volunteer programme such as this one are present in many areas.(ABSTRACT TRUNCATED AT 400 WORDS)

Activities of Daily Living↗
PubMed2005

Developing functional outcome measures for unilateral neglect: a pilot study.

Stroke patients may develop personal neglect, peripersonal neglect or both. Four new measures were tested in a sample of 42 right-handed inpatients (25 male; 17 female, median age 72 years). Participants removed keys from a rack, identified grocery items, washed their face, and cleaned a tray. Prior to this, they were classified as: no neglect (15), personal neglect (8), peripersonal neglect (7), and both personal and peripersonal neglect (12). The sensitivity and specificity of each new measure was determined by agreement with the classification. Test-retest reliability was determined using weighted kappa statistics or limits of agreement. Four occupational therapists (OTs) rated videos of the face and tray measures, and software was developed to measure objectively time spent and area covered on Face and Tray. Keys and Grocery had high specificity, good reliability but poor sensitivity. For the OTs' video ratings, there was good and moderate inter-rater reliability on Tray and Face respectively for area covered, but not time spent. Intra-rater reliability was also better for area than time on Tray. However, the validity of Face and Tray themselves is currently inadequate. A longitudinal study is proposed to modify the measures, increase their sensitivity and evaluate their ability to monitor change over time.

Aged↗
PubMed1984

Sex role orientation, personality structure, and adjustment in women.

In an effort to clarify and expand the theoretical foundation for behavioral researches on androgyny the present study, through an extensive literature review, attempted to establish personality structure as a function of masculine instrumentality (M) and feminine expressivity (F) in females. Results were strong and confirming, suggesting that considerable relationship may exist between certain sex role socialization practices and general personality development. In addition, the implications of instrumentality and expressivity for adjustment were investigated through a planned contrast of clinical and normal groups, with the expectation that feminine females would appear more frequently in the clinical group. However, results clarified that it is the lack of masculine instrumentality in the personality, not the feminine role per se, which is implicated in mental illness. These findings lend clarity to previous researches on androgyny and adjustment. Implications for feminine socialization and ego psychology are considered.

Adolescent↗
PubMed2003

Dietary fats and the risk of incident Alzheimer disease.

BACKGROUND: Few studies have investigated the effects of dietary fats on the development of Alzheimer disease. We examined the associations between intake of specific types of fat and incident Alzheimer disease in a biracial community study. METHODS: We performed clinical evaluations on a stratified random sample of 815 community residents aged 65 years and older who were unaffected by Alzheimer disease at baseline and who completed a food-frequency questionnaire a mean of 2.3 years before clinical evaluation. RESULTS: After a mean follow-up of 3.9 years, 131 persons developed Alzheimer disease. Intakes of saturated fat and trans-unsaturated fat were positively associated with risk of Alzheimer disease, whereas intakes of omega-6 polyunsaturated fat and monounsaturated fat were inversely associated. Persons in the upper fifth of saturated-fat intake had 2.2 times the risk of incident Alzheimer disease compared with persons in the lowest fifth in a multivariable model adjusted for age, sex, race, education, and apolipoprotein E epsilon4 allele status (95% confidence interval, 1.1-4.7). Risk also increased with consumption of trans-unsaturated fats, beginning with the second fifth of intake (relative risk, 2.4 compared with the lowest fifth; 95% confidence interval, 1.1-5.3). We observed linear inverse associations between Alzheimer disease and vegetable fat (P =.002), and, after further adjustment for other types of fat, marginally significant associations with intake of omega-6 polyunsaturated fat (P =.10 for trend) and monounsaturated fat (P =.10 for trend). Intakes of total fat, animal fat, and dietary cholesterol were not associated with Alzheimer disease. CONCLUSION: High intake of unsaturated, unhydrogenated fats may be protective against Alzheimer disease, whereas intake of saturated or trans-unsaturated (hydrogenated) fats may increase risk.

Aged↗
PubMed1999

[Measurement and evaluation of natural and artificial UV radiation].

Natural and artificial UV radiation are environmental factors with both beneficial and harmful biological effects. This article will explain the physical measurement quantities and their relation to the biologically effective dose and will summarize the present technical state of the art of personal UV monitoring. In practical use are dosimeters based on polysulphone, a polymer which undergoes changes in its optical properties upon irradiation with UV. Other systems determine the UV dose by quantifying damage induced in Bacillus subtilis spores upon UV exposure. An electronic UV sensor represents a new and interesting development. Personal UV dosimeters will become an useful tool in both clinical and scientific areas within dermatology.

Dose-Response Relationship, Radiation↗