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PubMedDate not supplied

Desktop image analysis: workstations of the future.

We report the use of an interactive graphics-oriented workstation to explore quantitative information extracted from medical images. At the University of California at Los Angeles, a Macintosh II personal computer operates as a stand-alone system and images are imported from a central PACS (picture archiving and communication system) server through an Ethernet network. The image-analysis program contains a complete set of general-purpose tools for image manipulation and processing, as well as specific tools for clinical analysis of cardiac and vascular images obtained by various techniques. Most of these features were designed to communicate information through color-coded graphic displays. Ten novice users were given a brief introduction to the program and asked to perform eight analytic tasks. The overall success rate was 95%, and the subjects considered the program easy to use without a manual or formal training. We conclude that with a well-designed graphic interface, physicians without training in the use of computers can easily learn to manipulate and analyze medical images.

Computer Graphics↗
PubMed1977

An automated cerebral blood flow analyzer: concise communication.

We present an automated cerebral blood-flow (CBF) analyzer can be used as an intermittent CBF monitor during carotid endarterectomies. Given a 1-min sample of an intracarotid injection of xenon-133, this device will display a CBF value with a range from zero to 200 ml/100 g per min. Results from this CBF analyzer were compared with those from manual computations in 181 separate determinations during 51 surgical procedures. The analyzer is effective, accurate, and reliable.

Carotid Arteries↗
PubMed1987

The design of design teams in high-technology industries.

Every design enterprise in high-technology involves a large multi-disciplinary team. In the context of man-machine interaction there are two related issues concerning the design system. Firstly, the team must be divided into sub-teams which can complete separate tasks within the context of the total system concept. Secondly, there are human factors design issues which often run across the work of the sub-teams. The division of a design effort into separate tasks is a considerable art but there are some general principles such as the minimisation of communication across interfaces and the standardisation of procedures for consolidating, communicating and recording design decisions. A human factors service must be available on a wide range of issues, including coding and storage of information concerning progress to date, the man-machine interfaces, work space and working environment design, and the design of instruction manuals. The ergonomist cannot confine his solutions within design. There are complementary issues of training which are usually organisationally separated. The ergonomist must cooperate with personnel specialists responsible for staffing levels and training. In recent years useful bridges have developed in the form of common interests in task analysis and simulation.

Journal Article↗
PubMed2006

Potential effects of hyperbaric oxygen therapy in acute pancreatitis.

BACKGROUND: To extract from the biomedical published reports, the effects of hyperbaric oxygen (HBO) on inflammatory disease, in particular acute pancreatitis. METHODS: This review will explain these effects and evaluate potential mechanisms of action of HBO in acute pancreatitis. A Medline/PubMed search (January 1966 to July 2004) with manual cross-referencing was conducted, including all relevant articles investigating the molecular and systemic effects of HBO on inflammatory diseases, particularly focusing on the studies of acute pancreatitis. All publication types, languages and subsets were searched. RESULTS: Original and review articles and short communications were extracted. The selected original articles covered the molecular and systemic effects of HBO and the effects in inflammatory disease states. The major findings are that HBO can act as an anti-inflammatory agent and as an antimicrobial agent. Many of the effects of HBO would be beneficial in the treatment of acute severe pancreatitis. Work carried out to date in animal models of acute pancreatitis shows promising improvements in severity but studies are limited to date. CONCLUSION: Acute pancreatitis impairs the pancreatic and systemic microcirculation and causes acute inflammation. These processes are potentially improved by HBO therapy.

Humans↗
PubMed2002

Extended attributes of event monitor systems for criteria-based notification modalities.

The efficacy of event monitors (EMs) at reducing morbidity and mortality of certain clinical conditions (CCs) is well established. In addition, studies have shown that user inverted exclamation mark s preferences on the modality of notification are correlated to the type of reminder or alert. Nonetheless, few institutions have implemented large scale automated monitoring of a considerable number of distinct CCs, and to our knowledge, none of these sizable projects also offer user-customizable communication modalities (CMs) over all monitored conditions. As both the numbers of CMs and CCs increase, the complexity of customizing user preferences amplifies following a geometric progression. This paper demonstrates an automated approach, based on generic notification attributes (NAs) and notification criteria (NC), which significantly simplifies the management and personalization of the CMs for institutions where the manual assignment of a CM for every alert is forbidding. The methods by which these NAs were developed, their significance for existing CCs and their implementation using the Arden Syntax and Guideline interchange format (GLIF) are described. The proposed Criteria-Based Notification is shown to improve two facets of the management of event monitors: 1) the assignment of CMs becomes independent from clinical conditions, de-facto removing institution-specific CMs from the knowledge bases of the event monitors and inserting CC-specific and institution-independent NAs, thus increasing their reusability and sharability; 2) knowledge-based independent NAs facilitate both institution-level management and user-level preference configuration.

Decision Making, Computer-Assisted↗
PubMed1989

Interactive microcomputer for acquisition of patient information.

Written records and first-generation hospital information systems do not meet their primary purpose to assist physicians in solving patients' problems. Simply automating the present chart formats is not the answer. An example of the concept needed for charting is the intensive care unit chart. Anesthesiology charts provide little useful information for the continued care of the patient postoperatively. They serve principally as legal archival documents. Automation of the anesthesia record should free the anesthesiologist of the need to search for preoperative information and to manually record most information intraoperatively. Decisions about how much data to archive and how to extract the data pertinent to continuing care are the challenges for physicians. The technologic tools are available for the design and implementation of a software system that focuses on effective communication of the patient's problems throughout the perioperative period as the patient moves from ward to operating room, through the recovery room and intensive care unit, and to the ward and home.

Anesthesiology↗
PubMed2003

3: Rehabilitation principles for treating chronic musculoskeletal injuries.

Evaluation of patients for rehabilitation after musculoskeletal injury involves identifying, grading and assessing the injury and its impact on the patient's normal activities. Management is guided by a multidisciplinary team, comprising the patient, doctor and physical therapist, with other health professionals recruited as required. Parallel interventions involving the various team members are specified in a customised management plan. The key component of the plan is active mobilisation utilising strengthening, flexibility and endurance exercise programs. Passive physical treatments (heat, ice, and manual therapy), as well as drug therapy and psychological interventions, are used as adjunctive therapy. Biomechanical devices or techniques (eg, orthotic devices) may also be helpful. Coexisting conditions such as depression and drug dependence are treated at the same time as the injury. Effective team communication, simulated environmental testing and, for those employed, contact with the employer facilitate a staged return to normal living, sports and occupational activities.

Biomechanical Phenomena↗
PubMedDate not supplied

Scanner technology for data-based decision making.

Scanner systems offer several benefits to nurse executives. Clinical, educational, and administrative data can guide the nurse executive's decisions providing greater control over patient care outcomes. Information from large patient care data sets provides a powerful tool for persuading executives in other departments. Additionally, the nurse executive who can eliminate the need for personnel to conduct time consuming and costly manual data entry, may be able to justify financial support for continued development of the nursing department's information system and technological training for the staff. In this way, scanner technology meets the immediate need for information and serves as an entry to more advanced communications systems.

Electronic Data Processing↗
PubMedDate not supplied

[Pharmacology and pharmacy on the INTERNET].

The article is devoted to the information on pharmacology and pharmacy which can be found in Internet. It contains Internet addresses of departments and faculties of pharmacology and pharmacy, manuals and textbooks, tests, scientific societies. The article also includes some information about discussion groups and grants.

Computer Communication Networks↗
PubMed1992

Epidemiology of rheumatic diseases in rural and urban populations in Indonesia: a World Health Organisation International League Against Rheumatism COPCORD study, stage I, phase 2.

To determine the incidence of musculoskeletal pain, disabilities, and help seeking behaviour, a questionnaire was administered to a rural population of 2184 men and 2499 women and an urban population of 481 men and 590 women aged over 15 years by house to house interviews with completion rates of 95.2% (rural) and 97.1% (urban). The incidences of pain in the joints, back, or neck were 23.6% (rural) and 31.3% (urban). The incidence of disability due to an inability to walk, lift, carry, and dress was 2.8% (rural) and 0.9% (urban). The percentage of the population with pain who had to stop work owing to disability was 75% (rural) and 78% (urban). Official health care facilities were used by 62% (rural) and 71% (urban) of the population. Traditional health care was used by 87% (rural) and 89% (urban). The high percentage of subjects unable to work was due to a predominance of manual labour occupations (rural, 90%, urban, 80%). The age and sex specific incidence of rheumatic diseases in these populations were similar to other developing and developed countries. The primary rheumatology service was inadequate due to the low priority given by the health service to non-communicable diseases and inadequate rheumatology teaching of the primary health care doctors during undergraduate training. Musculoskeletal pain is a major public health problem in Indonesia and is still not fully appreciated.

Adolescent↗
PubMed1986

Interview, diagnostic, and legal aspects in the forensic psychiatric assessments of deaf persons.

Forensic psychiatric assessments rely on many underlying presumptions concerning the language development and abilities of their subjects. Although these assumptions may apply across a culturally diverse group of hearing subjects, they probably do not apply to those who are prelingually deaf because such deaf persons never developed verbal language. In this article, a review of the range of literature focusing upon the unique aspects of interviews, diagnosis, and legal understanding of the deaf is conducted. An attempt to illuminate those features believed to be most relevant to forensic assessments of this unique population is made. The demands of interviews conducted in manual language are discussed and particular attention is paid to the impact of the interpreter upon confidentiality, privilege, agency, and the dynamics of the interview. It is also suggested that many of the baseline behaviors of the deaf may, at least partly, result from differences in communication style between the deaf and hearing. This article reports that many major mental disorders occur with the same frequency among the deaf and hearing and include many of the same symptoms. However, organic mental disorders may occur at a somewhat greater rate among the deaf because of the organic basis of deafness. Finally, the ways in which deafness and the use of an interpreter may influence the deaf person's ability to understand and relate to legal concepts and process are discussed. It is noted that many of these problems may arise from a deaf persons inexperience or undereducation about legal matters rather than psychopathology.

Deafness↗
PubMedDate not supplied

[Diagnosis and classification in psychiatric disorders].

This paper provides a general overview of the evolution of the diagnostic concepts in Psychiatry, of the research methods for future improvement, of the goals reached and of the deterrants that have to be surpassed. Classification, standardization and systematization of mental disorders has not been an easy task. For this reason, during a long period of time a wide diversity in the classification of the mental illness that ran along with the thinking trend of each and everyone of the different authors has been observed. This resulted in a division of the specialty and in the contamination of its ideologies and also, it has damaged the reputation of the diagnosis. The development of psychopharmacology and of the epidemiological systems made necessary the implementation of a strict diagnostic system that could make possible the planning of treatments, the establishment of prognosis and the design of preventive measurements. England was the cradle of this change due to the fact that the situation of the specialty availed itself of the influence of the prestigious and noteworthy German professors exiled in this country. Since 1972, some of the material that has been published illustrates the new tendency of nosology. Since then, there has been a great proliferation of works in this field. The culminating point of these investigations is represented by the Diagnosis and Statistical Manual of the American Psychiatric Association and by the International Classification of Illnesses (ICD-10). From this point of view, diagnosis is just a provisional hypothesis of a work that can be identified because of its pathological expressions and which is also of help in the communication between specialists.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans↗
PubMed1979

Clinical and arthrographic studies on the valve mechanism in communicating popliteal cysts.

Forty-one knee joints presenting with significant popliteal cysts were examined clinically and arthrographically. The fluid was aspirated from the cysts and replaced by contrast medium of low viscosity. On knee flexion the contrast fluid spontaneously passed over into the joint in 16 cases (no valve mechanism), in 7 small amounts of fluid were forced into the joint when the cysts were manually compressed, and in 18 no fluid passage to the joint was observed on manipulation (valve mechanism). When a valvular action was established, effusion in the joint was rare and the fluid from the cyst was usually viscous. The cysts with a valvular connection were significantly larger than those without a valve mechanism.

Adult↗
PubMed1997

Language bias in randomised controlled trials published in English and German.

BACKGROUND: Some randomised controlled trials (RCTs) done in German-speaking Europe are published in international English-language journals and others in national German-language journals. We assessed whether authors are more likely to report trials with statistically significant results in English than in German. METHODS: We studied pairs of RCT reports, matched for first author and time of publication, with one report published in German and the other in English. Pairs were identified from reports round in a manual search of five leading German-language journals and from reports published by the same authors in English found on Medline. Quality of methods and reporting were assessed with two different scales by two investigators who were unaware of authors' identities, affiliations, and other characteristics of trial reports. Main study endpoints were selected by two investigators who were unaware of trial results. Our main outcome was the number of pairs of studies in which the levels of significance (shown by p values) were discordant. FINDINGS: 62 eligible pairs of reports were identified but 19 (31%) were excluded because they were duplicate publications. A further three pairs (5%) were excluded because no p values were given. The remaining 40 pairs were analysed. Design characteristics and quality features were similar for reports in both languages. Only 35% of German-language articles, compared with 62% of English-language articles, reported significant (p < 0.05) differences in the main endpoint between study and control groups (p = 0.002 by McNemar's test). Logistic regression showed that the only characteristic that predicted publication in an English-language journal was a significant result. The odds ratio for publication of trials with significant results in English was 3.75 (95% CI 1.25-11.3). INTERPRETATION: Authors were more likely to publish RCTs in an English-language journal if the results were statistically significant. English language bias may, therefore, be introduced in reviews and meta-analyses if they include only trials reported in English. The effort of the Cochrane Collaboration to identify as many controlled trials as possible, through the manual search of many medical journals published in different languages will help to reduce such bias.

Bias↗
PubMed2004

Dissociating linguistic and nonlinguistic gestural communication in the brain.

Gestures of the face, arms, and hands are components of signed languages used by Deaf people. Signaling codes, such as the racecourse betting code known as Tic Tac, are also made up of such gestures. Tic Tac lacks the phonological structure of British Sign Language (BSL) but is similar in terms of its visual and articulatory components. Using fMRI, we compared the neural correlates of viewing a gestural language (BSL) and a manual-brachial code (Tic Tac) relative to a low-level baseline task. We compared three groups: Deaf native signers, hearing native signers, and hearing nonsigners. None of the participants had any knowledge of Tic Tac. All three groups activated an extensive frontal-posterior network in response to both types of stimuli. Superior temporal cortex, including the planum temporale, was activated bilaterally in response to both types of gesture in all groups, irrespective of hearing status. The engagement of these traditionally auditory processing regions was greater in Deaf than hearing participants. These data suggest that the planum temporale may be responsive to visual movement in both deaf and hearing people, yet when hearing is absent early in development, the visual processing role of this region is enhanced. Greater activation for BSL than Tic Tac was observed in signers, but not in nonsigners, in the left posterior superior temporal sulcus and gyrus, extending into the supramarginal gyrus. This suggests that the left posterior perisylvian cortex is of fundamental importance to language processing, regardless of the modality in which it is conveyed.

Adolescent↗
PubMed1992

On the evolution of language and generativity.

One of the properties that most conspicuously distinguishes human language from any other form of animal communication is generativity. Language with this property therefore presumably evolved with the Homo line somewhere between H. habilis and H. sapiens sapiens. Some have suggested that it emerged relatively suddenly and completely with H. sapiens sapiens, and this view is consistent with (a) linguistic estimates as to when vocal language emerged, (b) the relatively late "explosion" of manufacture and cultural artifacts such as body ornamentation and cave drawings, and (c) evidence on changes in the vocal apparatus. However, evidence on brain size and developmental patterns of growth suggests an earlier origin and a more continuous evolution. I propose that these scenarios can be reconciled if it is supposed that generative language evolved, perhaps from H. habilis on, as a system of manual gestures, but switched to a predominantly vocal system with H. sapiens sapiens. The subsequent "cultural explosion" can then be attributed to the freeing of the hands from primary involvement in language, so that they could be exploited, along with generativity, for manufacture, art, and other activities.

Brain↗
PubMed1996

Brief communication: when Adam delved ... an activity-related lesion in three human skeletal populations.

A rare, activity-related lesion, the clay-shoveller's fracture, was identified during osteological analysis in three human populations dating from the Roman to the later Medieval period in England, circa fourth to 14th centuries A.D. The prevalence of this fracture in these populations suggests an osteological indicator for several possible manual activities, but also one that may be the result of a long-standing human subsistence adaptation requiring digging in the soil. Since males as opposed to females appear to be preferentially affected, the occurrence of such injuries has the potential to provide an insight into the sexual division of labor in earlier human populations.

Adult↗