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At least 1,009 records · Page 56Linked to original sources
PubMed1975

Pathogenesis of staphylococcal infections of the skin.

Staphylococcus aureus does not grow readily on normal skin, where an important factor inhibiting its growth is the resident flora. Hydration of the stratum corneum favors the growth of S. aureus. Before lesions of staphyloderma are produced, organisms multiply on the surface. Substances produced as the result of multiplication enter the skin and produce an irritant reaction characterized by necrobiosis, spongiosis followed by perivascular infiltration, exocytosis and intraepidermal vesicle formation. A technique was used whereby the skin surface was separated from growing S. aureus by a filter. Pustules were produced through the filter.

Humans↗
PubMed1983

A statistical analysis of a pediatric dermatology clinic.

Statistical analysis was performed of the diseases seen and therapies utilized during the first two years of the Pediatric Dermatology Clinic at the University of Miami School of Medicine, Miami, Florida. This survey includes 2,821 patient visits made by 1,578 patients. This analysis classifies patients by diagnosis, sex, age, race, and treatment. Diagnostic and treatment frequencies, sex and race ratios, and trends in the patient's age at presentation are also noted. This survey reveals a wide spectrum of pediatric dermatologic disease with 154 different diagnoses made. A review of the 86 different therapeutic modalities utilized is also presented.

Acne Vulgaris↗
PubMed1977

Cutaneous microflora of patients with repeated skin infections.

The microflora of normal skin in 16 patients with repeated staphylococcal and streptococcal skin infections was examined to determine whether abnormalities existed which would indicate a protective role for the indigenous flora against colonization by pathogens. Five sites-hands, feet, axilla, groin and back-were examined quantitatively and qualitatively and compared with a control group. Total populations of indigenous flora were significantly higher from patients with repeated skin infections of the back, axillae and feet. The frequency of isolation of different species from normal skin was comparable between the control and experimental groups, with the exception of the incidence of Staphylococcus aureus and Proteus species which were isolated only from patients with repeated skin infections. Gram-negative bacteria were isolated with comparable frequency between the two groups, but patients with repeated skin infections tended to carry gram-negative bacteria on multiple sites. It was concluded from the high population of indigenous flora and the types of microogranisms present that the microflora of normal skin did not appear to protect patients with repeated skin infections against colonization by pathogens. The presence of high populations of Staphylococcus aureus on the normal skin of patients with repeated skin infections would appear to be the most important contributing factor.

Bacteria↗