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The aim of this review article is to provide a clinical guideline for the child presenting with easy bruising, distinguishing among the different etiologic groups associated with this symptom what is normal and what is not, allowing then to establish an algorithm for work-up and follow-up. We also precise in which concrete situation it would be necessary to refer the child to a pediatric hematologist.
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Two children, four and two years old, played on top of wheat, that had been fumigated with malathion, pyrethrum and phosphine. Both died within 18 hours. Because after the autopsy, death could not be attributed to any organic or violent cause, a toxicological analysis was carried out. No drugs, except alcohol, was detected. Those results were attributed to hydrolysis of malathion, yielding two molecules of ethanol. As this was an indirect proof of malathion ingestion, it was assumed that phosphine had been ingested as well and that consequently this was the cause of death, because it is much more toxic than malathion and because it was continuously generated from not completely dissolved aluminiumphosphide tablets, while the children were still playing.
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The first steps in the identification of the cause of a bleeding disorder is careful evaluation of the patient's haemostatic competence and an assessment of the personal and family histories. Laboratory assessment should be guided by the clinical impression.
Invasive infections in humans with organisms from the fungal subclass Zygomycetes are most commonly seen in immunocompromised and diabetic patients. Rarely, such fungal infections may be seen in immunocompetent, nondiabetic individuals. In these cases, cutaneous trauma with direct implantation of fungal organisms into the wound from soil contamination is the frequent scenario. We present the case of a 31-year-old gravid woman involved in a single-vehicle automobile accident who presented to our institution with severe head trauma. On admission, a small ecchymotic area on her right forearm was noted. The lesion eventually expanded and ulcerated. Culture and histologic examination of tissue from the site revealed fungal organisms consistent with Zygomycetes. Subsequent studies confirmed the fungal organism as Apophysomyces elegans. Antifungal therapy was initiated, and multiple debridements were performed. Amputation of the right arm above the elbow was eventually necessary, but aggressive surgical intervention and antifungal therapy were unsuccessful in preventing the spread of the infection. The patient died 2 weeks after admission from polymicrobial sepsis. This case illustrates the dangerously invasive nature of A elegans, even in immunocompetent individuals.
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Autologous bone grafts for alveolar ridge augmentation are the gold standard for restoring atrophic residual ridges in preprosthetic surgery. Many indications, donor sites, and techniques have been reported. The purpose of this article is to review the anatomy, surgical technique, and potential complications associated with proximal tibia bone harvest. A consecutive series of 44 patients who underwent proximal tibia bone graft harvest between 2000 and 2003 was studied by retrospective chart review. Five major and 7 minor complications were observed; overall morbidity was low. A significant amount of corticocancellous bone may be harvested from the proximal tibia with minimal morbidity.
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The United Nations Convention against torture prohibits repatriation of refugees if there is reason to believe they will be tortured on return to their country. A history of torture is therefore an important factor in making a case for asylum. In this study, the results of the medical examinations of 59 torture victims investigated at the Department of Forensic Medicine, University of Aarhus, Denmark, 1996-2002, are presented and discussed. Variables including age, sex, education, health, torture methods, condition of confinement, torture aftereffects, and findings at the forensic examination were registered in a database (Paradox) and analyzed. In 70%, aftereffects of torture could be documented. These included scars after fixation, burns, incisions, or flogging. Symptoms and signs from joints, muscles, and nerves were common in victims who had been suspended. Many of the victims of phalanga had painful feet and signs of walking impairment. A majority of the victims suffered from posttraumatic stress syndrome. An independent medical report offers an opportunity to evaluate and elaborate the story told by the victim and should be used in disputed cases. We have a duty to protect refugees against torture.
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