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PubMed1991

Pathological mimics of chronic inflammatory bowel disease.

When all of the macroscopic and microscopic features of Crohn's disease and ulcerative colitis are present, the correct diagnosis is usually made without difficulty. When some of the changes are absent, the accuracy of diagnosis is reduced. This review has outlined those diseases which feature some of these pathological changes and may masquerade as idiopathic chronic inflammatory bowel disease. Some of the pathological mimics are iatrogenic while other common diseases, such as bacterial infection, ischaemia, and diverticulosis may produce confusing histological appearances. The picture is complicated by the fact that many of these pathological imitators may themselves cause or predispose to chronic inflammatory bowel disease, or may complicate chronic inflammatory bowel disease. For example, drugs and infectious agents are recognisable causes of relapse in ulcerative colitis; Crohn's disease may cause diverticulitis in patients with diverticulosis; and lymphoma may complicate ulcerative colitis. It behooves all practising histopathologists to recognise these mimics of ulcerative colitis and Crohn's disease to ensure appropriate management for patients with inflammatory pathology of the intestines.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMed1989

Coexistent Crohn's disease and sigmoid diverticulosis.

This study reports six patients with a diagnosis of diverticular disease with associated localized Crohn's colitis who were all treated by segmental resection. Two patients died in the post-operative period from disease unrelated to their colonic pathology. The remaining four patients remain well, show no signs of recurrent disease and have required no further surgery. The behaviour and significance of the two conditions occurring in the same patient is discussed.

Aged↗
PubMed1983

Simultaneous recording of myoelectrical activity and resistance from the human colon.

A system used to record myoelectrical activity from the rectosigmoid colon has been modified so that a continuous recording of electrical resistance is obtained simultaneously. Normal subjects, patients with diverticular disease and patients with the irritable colon syndrome have been studied by this method. There were variations in resistance in the form of waves for 74.7, 88.5 and 89.0% of the time in the three groups. These changes were abolished by intravenous glucagon. The predominant frequency of the waves was 2-4 c/min and often coincided with myoelectrical waves of the same frequency. It is concluded that the resistance changes are produced by local movement in the colonic wall at the electrode site and that this technique may be valuable in studying colonic motility.

Colon↗
PubMed2001

[Determination of colon resection limits in diverticulosis].

Results of surgical treatment of 112 patients with colon diverticulosis are analyzed. It is established that during operation it is necessary to perform such scope of resection which permits to create anastomosis between colon parts without their discoordination. The risk of complications from anastomosis decreases to 3.7%. The creation of anastomosis with significant discoordination leads to high risk of its insufficiency. It is desirable to resect the colon's parts with moderate discoordination. When the extension of of resection margins due to parts with moderate discoordination is dangerous, it is possible to create the anastomosis with ileo- or colostoma. In this case the risk of inflammatory complications remains, but conservative treatment of these complications in the conditions of feces efflux is effective.

Adult↗