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Temperament, activity, and expectations for later personality development.

Temperament is assumed to be the biologically based, emotional core of personality. Adult personality is presumed to emerge developmentally from temperament. One mechanism that may link temperament to subsequent personality development involves caregiver expectancies. Stability in personality may be associated with caregiver expectancies about the meaning of temperament-based behavior. The expectancies, in combination with implicit theories of personality development, support stability and patterned change. This multimethod study examined the relations among motor activity differences, temperament, and expectations about future personality characteristics in preschool children. It was hypothesized that motor activity and temperament differences would be linked to teachers' expectations about later personality development. The hypothesis that expectations about such links would be moderated by the sex of the child was also examined. Outcomes generally corroborated hypotheses. Results are discussed in terms of personality development and age-related adaptations to social contexts.

Adaptation, Psychological↗

Relationships between conscientiousness, self-efficacy, self-deception, and learning over time.

The present study examined the dual mediating effects of self-efficacy and self-deception on the relationship between conscientiousness and learning over time. Data from 134 college students were used to investigate the relative impact of self-efficacy and self-deception. Consistent with the hypothesized model, conscientiousness was significantly and positively related to both early training self-efficacy and self-deception, and both self-efficacy and self-deception had significant effects on learning but in opposite directions. Furthermore, the relative impact of self-efficacy and self-deception on learning changed over time as expected. The negative effect of self-deception in early stages of training disappeared at later stages of training but the positive effects of self-efficacy remained. Support was not found for self-efficacy and self-deception as mediators of the conscientiousness-learning relationship.

Adult↗

Workplace safety performance: conscientiousness, cognitive failure, and their interaction.

This research investigated the effects of cognitive failure on workplace safety and accidents over 2 studies. It was hypothesized that cognitive failure would directly predict safety behavior and workplace accidents and predict these outcomes over and above conscientiousness. It was found that cognitive failure uniquely accounted for workplace safety behavior and accidents. However, it has been suggested by researchers that certain individual differences might interact to produce differential effects. Thus, a moderated model was tested examining the interaction of cognitive failure and conscientiousness. It was found that cognitive failure moderated the relationship between conscientiousness and accidents and unsafe work behaviors. Overall, results suggest that cognitive failure plays an important part in individual safety behavior, especially when conscientiousness is low.

Accidents, Occupational↗

Ethical issues in living organ donation: donor autonomy and beyond.

Despite nearly 50 years of experience with living kidney donation, ethical questions about this practice continue to haunt us today. In this editorial I will address two of them: (1) Given the possibility of limited understanding and coercion, how can we be sure that a person who offers to donate an organ is acting autonomously? and (2) Do people have a right to donate? The universal requirement for informed consent is the traditional method for ensuring that a person is acting autonomously. But, while obtaining fully informed consent is desirable, it may not always be achievable or necessary. When the recipient is very dear to the potential donor, the donor may base his decision primarily on care and concern rather than on a careful weighing of risks and benefits. I will argue that consent that emanates from such deep affection should be considered just as valid as consent that is fully informed. But consent is not enough. There is no absolute right to donate an organ. If there were such a right, then some physician would be obligated to remove an offered organ upon request, regardless of the risks involved. I do not believe that physicians have such an obligation. Physicians are moral agents who are responsible for their actions and for the welfare of their patients. Therefore, while the values and goals of the potential donor should be given great weight during the decision-making process, physicians may justifiably refuse to participate in living organ donation when they believe that the risks for the donor outweigh the benefits.

Conscience↗

Origin of leg musculature during Drosophila metamorphosis.

Pro- and mesothoracic leg imaginal disks of late third-instar larvae of genotypes affecting the electrophoretic mobilities of alpha-glycerolphosphate dehydrogenase (EC 1.1.1.8) and arginine kinase (EC 2.7.3.3) were transplanted into host larvae of different genotypes. The metamorphosed implants were analyzed microscopically for the presence of musculature, histochemically for the distribution of enzyme activity, and electrophoretically for determination of the phenotypes of the two muscle-marker enzymes. The results permit the conclusion that leg imaginal disks contain muscle stem-cells.

Adipose Tissue↗

Inducibility of spleen focus-forming virus by BrdUrd is controlled by the differentiated state of the cell.

All Friend cells--except thymidine kinase (ATP:thymidine 5'-phosphotransferase, EC 2.7.1.21)-deficient mutants--are highly inducible for the release of biologically active spleen focus-forming virus (SFFV) after exposure to BrdUrd. We studied SFFV production in somatic cell hybrids made between Friend leukemia cells (FLC) and cells expressing various differentiation programs. High inducibility of SFFV and release of constitutive Friend virus (FV) and SFFV are eliminated in all hybrids in which the potential for erythroid differentiation is suppressed. FV release and its induction by BrdUrd are unchanged in hybrids that maintain the expression of erythroid differentiation.

Animals↗

Altered protein kinase C in a mast cell variant defective in exocytosis.

The murine mast cell line PB-3c is dependent on interleukin 3 (IL-3) with respect to survival and proliferation. These cells also require IL-3 to display antigen-mediated serotonin release, which is coupled to a transient increase of cytosolic free calcium ([Ca2+]i). The antigen-mediated exocytosis is inhibited by phorbol 12-tetradecanoate 13-acetate (PTA), an activator of phospholipid/Ca2+-sensitive protein kinase. In contrast, the malignant mast cell variant PB-1 is IL-3 independent with respect to proliferation but is unable to undergo antigen-mediated exocytosis. Yet this cell line exhibits basal levels of [Ca2+]i, serotonin content, and numbers of IgE receptors comparable to those of PB-3c cells. Subcellular distribution studies revealed that the specific activity of cytosolic protein kinase C of PB-1 cells was only 40% of that found in PB-3c cells. Furthermore, the PB-1 cells showed a significantly higher specific activity of membrane-bound protein kinase C than PB-3c cells. Scatchard plot analysis of [3H]-phorbol 12,13-dibutyrate binding to intact PB-1 cells demonstrated the presence of 20% high-affinity (Kd = 6 nM) and 80% low-affinity (Kd = 60 nM) phorbol ester receptors, whereas PB-3c cells displayed only the low-affinity phorbol ester binding. Immunological characterization of protein kinase C from both cell lines revealed the presence of a normal 77-kDa protein kinase C holoenzyme in both cell lines. In addition, a 72-kDa protein kinase C-related protein band was found mainly in the membrane fraction of the PB-1 variant. It is suggested that this altered and membrane-bound form of protein kinase C may be involved in the blockage of the antigen-mediated exocytosis of PB-1 cells.

Animals↗

Conscientious refusal and a doctors's right to quit.

Patients sometimes request procedures their doctors find morally objectionable. Do doctors have a right of conscientious refusal? I argue that conscientious refusal is justified only if the doctor's refusal does not make the patient worse off than she would have been had she gone to another doctor in the first place. From this approach I derive conclusions about the duty to refer and facilitate transfer, whether doctors may provide 'moral counseling,' whether doctors are obligated to provide objectionable procedures when no other doctor is available, why the moral consensus among doctors seems relevant even though it does not determine whether something is morally acceptable, and whether doctors should stay out of fields whose standard procedures they find morally unacceptable.

Conscience↗

Personality differences in hindsight bias.

Ten personality correlates of hindsight bias were tested in a study with 75 participants answering almanac-type knowledge questions. Participants showed hindsight bias when hindsight estimates were compared to foresight estimates (memory condition), when hindsight estimates were compared to foresight estimates of other participants (BS = between-subjects hypothetical condition), and when hindsight estimates were compared to foresight estimates in response to equally difficult control items (WS = within-subject hypothetical condition). The magnitude of hindsight bias in both hypothetical conditions was positively associated with the participant's field dependence and his or her tendency for favourable self-presentation (as measured by social desirability and impression management). Between-subjects hypothetical hindsight was associated with the participant's conscientiousness and need for predictability and control (as measured by a rigidity scale). In a multiple regression analysis, 39% of the variance in BS hypothetical hindsight, 24% of the variance in WS hypothetical hindsight, but no significant proportion of the variance in memory hindsight could be accounted for by personality measures. It is concluded that individual differences in hindsight bias exist and must be taken into account in a complete model of the effect.

Adult↗

Treating homosexuality: a response to Yarhouse.

Professor Mark A. Yarhouse proposes an 'identity synthesis' model of sexual modification therapy for homosexuals. This model is meant primarily to target the process by which one's sexual identity is synthesized, rather than the changing of sexual orientation itself. I highlight some of the advantages of Yarhouse's model along with some of its potential pitfalls. My primary point of departure with Yarhouse concerns how one ought to direct those self-identified homosexual clients who fall within our clinical sphere of influence and who, in the end, contrary to our better judgment, decide that they would like to pursue a course of "homosexualization." Based on the "autonomy" - emphasizing aspects of the identity synthesis model, it appears that Yarhouse is willing to sanction the referral of certain clients to "therapists" who are willing to facilitate these clients' homosexualization. I do not believe that Christians involved in the care of homosexuals can licitly participate in such referrals.

Behavior Therapy↗