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At least 1,009 records · Page 56Linked to original sources
PubMed2001

Autovaccination of dairy cows to treat post partum metritis caused by Actinomyces pyogenes.

Autovaccines are therapeutic vaccines manufactured from a disease causing micro-organism for individual treatment of patients, animals, or sometimes herds to treat chronic or recurrent infections. Despite the common use of autovaccines in veterinary medicine, their mechanism of action, i.e. the immunologic effector mechanism activated after administration, has never been investigated. Here we present data concerning the use of autovaccines to treat metritis infection in a group of dairy cows. Following autovaccination we observed a significant decrease in CD4+ cells paralleled by an increase in T-cells expressing the gammadelta-T-cell receptor (gammadelta-TCR) in the peripheral blood of the treated animals. Lymphocyte proliferation assays showed an initial increase in antigen-specific responsiveness followed by a decrease in this responsiveness during autovaccination treatment. We therefore conclude that administration of an autovaccine leads to the activation of immunologic effector mechanisms which contribute to recovery of the diseased animals.

Actinomyces↗
PubMed1986

Mandibular osteomyelitis caused by Actinomyces Israelii. Report of a case.

An unusual case of cervicofacial actinomycosis with cortical osteomyelitis of the ascending ramus is presented. The portal of entry of the infection was most probably by an extra oral route. The authors have emphasized the importance of repeated smear examinations, cultures, and sensitivity tests to rule out actinomycosis in such cervicofacial infections. The difficulties encountered in the isolation of A. Israelii are discussed.

Actinomyces↗
PubMed2006

Severe large bowel obstruction secondary to infection with Actinomyces israelii.

Abdomino-pelvic actinomycosis is a rare disease, which usually follows a chronic course. However, bowel obstruction may reveal an acute clinical picture. We report on a 38-y-old female with abdomino-pelvic actinomycosis, characterized by a 10 cm long filiform stenosis of the sigmoid colon and bilateral ovarian abscesses. She developed acute ileus that required emergency surgery.

Actinomyces↗