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At least 991 records · Page 55Linked to original sources
PubMed2003

Improving neurologic outcome in off-pump surgery: the "no touch" technique.

BACKGROUND: As patients referred for cardiac surgery include increasingly older individuals, the prevalence of comorbid factors, such as previous cerebrovascular disease, carotid disease, aortic atherosclerosis, and reoperations, is on the rise. Avoiding manipulation of the ascending aorta in this high-risk subgroup may become a necessity to perform safe coronary artery bypass grafting (CABG) surgery. METHODS: We retrospectively reviewed our database of 640 off-pump CABG patients and identified 84 patients in whom we adopted the "no touch" technique (NTT). Revascularization was carried out with single or bilateral internal thoracic arteries (ITA) and by connecting additional coronary grafts (saphenous vein, radial artery) in a T or Y configuration. The right gastroepiploic artery was used as a conduit in 2 patients. The brachiocephalic artery was used as an alternative inflow site in 3 patients (reoperation). RESULTS: Age, sex, risk factors, functional class, and history of congestive heart failure were comparable in the two groups. In the NTT group, the frequencies were higher for severe atherosclerosis of the aorta (13% versus 0%; P =.00), carotid disease (25% versus 16%; P =.02), and history of previous cerebrovascular accidents (17% versus 8%; P =.04). Complete revascularization was achieved in 96% of the patients in the off-pump CABG group, compared with 90% in the NTT group (P =.17). No differences in the prevalence of postoperative low cardiac output syndrome, intra-aortic balloon pump use, perioperative myocardial infarction, or operative mortality at 30 days were observed between the two groups. In the NTT group, weak trends toward a lower incidence of postoperative delirium (8% versus 15%; P =.12), a lower incidence of stroke (0% versus 1%; P =.85), and a shorter intensive care unit stay (P =.07) were observed. Hospital stay was also shorter in the NTT group (P =.04). CONCLUSION: Avoiding aortic manipulations in patients with severe atherosclerosis of the aorta, carotid disease, and a previous history of cerebrovascular accidents is technically feasible and is associated with a low risk of mortality and good shortterm results. Adopting this practice may reduce the incidence of stroke and improve early outcome in this subset of patients.

Cardiac Output, Low↗
PubMed2005

Role of fine needle aspirate mapping and touch imprint preparations in the evaluation of azoospermia.

OBJECTIVE: To assess the utility of fine needle aspiration cytology (FNAC) and touch imprint cytology (TIC) in the evaluation of azoospermia. STUDY DESIGN: FNAC, TIC and open testicular biopsy (OTB) were used to evaluate 31 azoospermic men. RESULTS: OTB revealed normal spermatogenesis (10), spermatogenic arrest (12), Sertoli cell only syndrome (SCO) (7) and unsatisfactory cases (2). Cytologic examinations (TIC vs. FNAC) revealed normal spermatogenesis (11 vs. 9), spermatogenic arrest (13 vs. 7), SCO (2 vs. 1) and unsatisfactory cases (5 vs. 5). Sensitivity and specificity of TIC and FNAC were 98% vs. 83% and 100% vs. 93%, respectively. CONCLUSION: Testicular FNAC is a reliable and simple method for the evaluation of azoospermia.

Adult↗
PubMed1991

[Double triangular resection technique at the feet of the cartilaginous arch in the correction of the nasal tip. "Do not touch the dome"].

Retropulsion and modelling of the nose tip can be obtained very simply without touching the dome by means of double triangular resection at the feet of the cartilaginous arch formed by the two alar cartilages. Static and dynamic effects are obtained retropulsion, elimination of the prominence of the superior border of the alar cartilage (without shortening resection) allowing creation of a finer nose tip; rounding of the nasal orifices, improving respiratory function; suppression of labial dependence of the tip a factor responsible for secondary ptosis of the tip.

Esthetics↗
PubMed1990

Survival of herpes simplex virus type 1 on some frequently touched objects in the home and public buildings.

The survival of herpes simplex virus type 1 in tissue culture fluid on doorknobs and washbasin tap handles over a 2 h period was investigated. The doorknobs were made of plastic and the taps had a chrome-plated surface. The stock virus suspension had a titre of 10(7.5) TCID50/0.1 ml, and a 0.01 ml droplet was placed on the objects. The droplets dried out after 35-40 min at room temperature (23-27 degrees C). The titre of infectious virus recovered by elution from the objects was determined at 0, 15, 30, 60 and 120 min. Infectious virus was recovered for all time periods studied. However, there was a marked drop in titre between 30 and 60 min. No differences were observed between virus placed on plastic and that on chrome-plate. Infectious virus could be isolated from skin after touching virus-contaminated doorknobs and taps with the middle finger of the right hand at all test times over a 2 h period.

Chromium↗
PubMed1985

Skin-surface touch print for diagnosing fungal infections.

The skin-surface touch print is a practical, easily performed and noninvasive method for obtaining a sample of infected stratum corneum or hair. This technique is particularly useful in diagnosing superficial fungal infections. With simple staining, fungal hyphae and spores can be readily visualized microscopically. This technique has been found to be as effective as the potassium hydroxide test.

Adhesives↗
PubMed1989

[Analysis of trophoblast subpopulations on touch smears of chorionic villi during normal pregnancy].

Trophoblasts of normal human pregnancy are classified into syncytiotrophoblasts (STs), cytotrophoblasts (CTs) and intermediate trophoblasts (ITs) which exist in cell columns and so forth. We analyzed the trophoblast subpopulations which appear on touch smears of chorionic villi morphologically and immunohistochemically, using the uterine contents of 37 cases of induced abortion. Troma 1, a rat monoclonal antibody, was utilized as a trophoblast marker and a mouse monoclonal antibody to HLA-A,B,C was employed to discriminate ITs from CTs. The results were as follows: 1. Two sorts of cells were positive for Troma 1 and therefore were considered to be trophoblastic: Multinuclear cells of various sizes and relatively large mononuclear cells. 2. Multinuclear trophoblasts were thought to be STs because of their characteristic cytomorphology and negative reaction for HLA-A,B,C. 3. The lower the gestational age was, the more ITs were observed. 4. The cellular and nuclear size of ITs varied and their chromatin was coarsely granular with aggregates. In addition one or more marked nucleoli were noted. Consequently it would be important to take care not to misdiagnose ITs as trophoblasts of a malignant nature.

Antibodies, Monoclonal↗
PubMed1986

Functioning parathyroid lipoadenoma. Report of a case diagnosed by intraoperative touch preparations.

Lipoadenoma of the parathyroid gland is an unusual cause of primary hyperparathyroidism. Inasmuch as they may grossly resemble lipoma more than parathyroid adenoma, these tumors may be missed by surgeons and surgical pathologists alike. In this case, the diagnosis was made during surgery utilizing touch preparations because frozen sections were technically difficult to perform due to the fat content of the tumor. Examination of multiple sections disclosed a neoplastic proliferation of parathyroid cells, thus supporting the premise that this entity represented an adenoma rather than a hamartoma.

Adenoma↗
PubMed1987

High tech-soft touch: breastfeeding issues.

Hospital practices and staff interactions need to be reviewed carefully in each institution and community to examine the direct or indirect effects on human lactation and breastfeeding. With the increased incidence of breastfeeding and the continued promotion by the Surgeon General and the American Academy of Pediatrics, it is imperative that health care professionals examine the attitudes that affect their behavior as they interact with their patients about lactation. The high-tech routines must be altered to facilitate the normal aspects of the breastfeeding process. A mother must be close to learn how to interact with and touch her new infant. The greatest challenge is not in changing the written policies nor the curtains or surroundings but in changing the attitudes and beliefs of the staff, so that human lactation and breastfeeding are treated as normal physiologic, psychological, and nurturing activities of mothers and infants.

Adult↗
PubMedDate not supplied

The tools of management: keeping high touch in a high tech world.

Three of Naisbitt's Megatrends: information processing, high tech/high touch and participatory management--welded into tools of management--have particular relevance for nurses throughout the world. Their use is explored in this paper delivered at a Special Interest Session in Tel Aviv at the ICN Congress.

Administrative Personnel↗
PubMed1984

Challenges for dietitians in a high tech/high touch society.

In our society, the coming decades will represent a period of great change and transition. Dietitians will come to realize that we have moved from an industrial to an information society. We are moving in the dual direction of high tech/high touch, matching each new technology with a compensatory human response. Institutional help will be replaced by self-reliance in all aspects of our lives. People whose lives are affected by a decision must be part of the process of arriving at that decision. We are giving up our dependence on hierarchical structures in favor of informal networks. For dietitians to prosper in this era of rapid technological change, they must more than keep pace; they must stay ahead, exploit technology aggressively and imaginatively, and apply it experimentally to new ideas.

Adolescent↗
PubMed1983

Pachometry: a comparison between touch and overlap measurement method.

Twelve human eyes had central corneal thickness measurements made by two investigators with the Haag-Streit 900 slitlamp and standard pachometer. Two endpoint methods were used for the final corneal thickness measurement setting in the microscope viewing eyepiece. The two methods used were (1) a touching of the epithelium/endothelium corneal split images and (2) an overlapping of the split images. Although final thickness measurements of the two investigators were similar, the results reveal a statistically significant difference for the two measurement methods.

Adult↗
PubMedDate not supplied

A menu-driven, touch panel microcomputer for clinical recordkeeping.

Quikchart is a menu-driven, touch-panel input microcomputer system designed for computer-naive physicians active in clinical environments. It enables them to generate patient encounter records, and to store and access them using electronic memory. It also permits printing hard-copy records. The system is designed so that the physician can do all this without resorting to a standard typewriter or computer keyboard. It circumvents the disadvantages of both handwritten records and dictated records. Upward expansion of Quikchart will allow individual systems to be networked into a clinic-wide medical record system.

Computers↗
PubMed1995

Novel fluorescence in situ hybridization approaches in solid tumors. Characterization of frozen specimens, touch preparations, and cytological preparations.

Fluorescence in situ hybridization has emerged as an extremely important tool for detection and characterization of nonrandom chromosome aberrations in cancer. Fluorescence in situ hybridization assays have been very reliable in cytogenetic tumor preparations, but have been more unpredictable in archival, paraffin-embedded specimens. We describe novel approaches for detection of chromosome aberrations in frozen tumor specimens, touch preparations, and cytological preparations. These approaches are both simple and reproducible, with minimal case-to-case variation in hybridization efficiency or hybridization signal quality. We demonstrate potential applications of these novel approaches by evaluating: 1) significance of normal karyotypes in malignant peripheral nerve sheath tumors; 2) p15/p16 copy number in prostate cancer; and 3) clonal chromosome 3p deletion in cytological preparations of pleural fluid from patients with mesothelioma.

Centromere↗
PubMedDate not supplied

Surgical "touch artefacts" of the cerebral cortex. An experimental study with light and electron microscopic analysis.

In surgically excised brain tissue a very common artefact, unrelated to the presence or absence of a genuine pathological process, involves the water content of cortical neurons. Nerve cells may show massive watery swelling of both their cytoplasm and nuclei or conversely may become shrunken and dark-staining. The most important aspect of this alteration is that it may lead to mistaken histopathological interpretation, but the question also arises whether such changes, presumably caused by exposure, touch, pressure or the combination of all 3, in the living patient, would persist after surgery and would eventually result in irreversible damage to the involved neurons? Thirty rats were operated in this experiment: craniotomy and opening of the dura mater was done over one convexity and slight pressure (uniformly calibrated for all animals) was applied to the exposed cortex. The wound was closed and the animals were sacrificed at various intervals, ranging from immediately after the operation to 6 weeks. The areas that suffered compression were examined by light and electron microscopy. Initial changes included marked watery swelling of neuronal perikarya and nuclei which predominated over pyknotic changes. The changes thus produced were identical with those seen in portions of the cortex excised immediately after pressure was applied to the area in 10 additional rats.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1995

Gastrospirillum hominis ("Helicobacter heilmanii"): a cause of gastritis, sometimes transient, better diagnosed by touch cytology?

OBJECTIVE: Besides Helicobacter pylori, another spirillar microorganism, provisionally called Gastrospirillum hominis, has been described in the human stomach in association with gastritis. The aim of this study was to assess the role of cytology in the diagnosis, to assess the gastritis associated with this infection, and to approach its natural history. METHODS: Charts and endoscopic biopsies and smears (touch cytology) from 28 patients with G. hominis seen between 1986 and 1992 were reviewed and compared with biopsies and smears from 28 patients with H. pylori gastritis. RESULTS: G. hominis was seen on smears from all 28 patients but diagnosed in only 15 of the corresponding sets of biopsies. No patient had evidence of H. pylori colonization. All patients had chronic antral gastritis with lymphoplasmocytes, and neutrophils were present in 13 patients. In addition, reactive changes were frequent: foveolar hyperplasia (n = 25), vasodilation (n = 23), lamina propria edema (n = 23), and increased intracytoplasmic mucin (n = 19). In contrast, intestinal metaplasia (n = 3) and glandular atrophy (n = 2) were infrequent, and lymphoid nodules were not seen. In patients with H. pylori, reactive changes were mild, and the lymphoplasmocytic infiltration was more intense (p < 0.005). Eleven patients had at least two endoscopic examinations with biopsies, with persistent colonization in only four. Seven patients cleared the infection with a concomitant regression of gastritis. CONCLUSIONS: G. hominis is more often detected in smears than biopsies. It is seen in association with a peculiar form of gastritis-associating chronic and reactive changes. Colonization may be a transient phenomenon and is never associated with H. pylori.

Adult↗
PubMedDate not supplied

Diagnosis of pituitary adenomas on touch preparations assisted by immunocytochemistry.

Touch preparations from surgically removed pituitary adenomas were studied by both routine staining and immunocytochemistry for all anterior pituitary hormones. The results were correlated with the histologic, histochemical, immunohistochemical and ultrastructural findings. Several features were recognized, some of them applicable in diagnosing various adenoma types: high cellularity, cell monomorphism, nuclear irregularities and heterogeneity of immunoreactivity, all major diagnostic criteria of pituitary adenoma. The presence of numerous fibrous bodies associated with nuclear pleomorphism, multinucleation and peripheral displacement of nuclei, in association with growth hormone (GH) immunopositivity, represent diagnostic criteria for sparsely granulated GH cell adenoma. The "Golgi" pattern of prolactin (PRL) immunopositivity in conjunction with the small size of cell and nucleus and the presence of microcalcifications represents diagnostic features of PRL-secreting adenoma. Cytoplasmic accumulation of hyaline material in association with peripheral distribution of periodic acid-Schiff stain and adrenocorticotropic hormone immunoreactivity is characteristic of sparsely granulated corticotroph cell adenoma. Knowledge and application of the described features may contribute significantly to the diagnostic approach to pituitary adenomas.

Adenoma↗
PubMed1993

Use of a community-based touch-screen public-access health information system.

Meeting the demands of patients and the public for health information is now a recognised aim. Healthpoint is a community-based touch-screen public-access health information system which aims to make health information easily accessible by the public and to provide feedback information on this demand. We have assessed Healthpoint in an experiment in three parts. Part one was a survey of 13 Healthpoints for several weeks in various community sites in Glasgow, such as a shopping centre, supermarket, library, and pub, as well as health service sites such as out-patient department and general practice. The number of users and the topics chosen were recorded by the systems. Part two was a survey of ten Healthpoints in one town (Clydebank) over five months, which examined routine information recorded by the system, and interviews with an opportunistic sample of 300 weekday shoppers in the street and a random sample of 271 by telephone. Part three was a survey of one Healthpoint in a general practice for 36 weeks using routine recording by the system and a postal survey of a systematic sample of 250 attenders. Seventy five (25%) out of 300 in the street survey and 45 (22%) of the telephone sample who had visited a site where there was a Healthpoint had used it. Overall, 17% of the telephone sample had used it. Seventy three (27%) out of 200 general practice attenders had used Healthpoint.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1993

[A successful case report of coronary artery bypass grafting with aortic no touch technique for the severely calcified ascending aorta].

Calcification of the ascending aorta may render aortic cross-clamping dangerous and aorta-coronary artery bypass grafting impossible. Coronary artery bypass grafting in a 72-year-old woman with drug resistant unstable angina and severely calcified ascending aorta owing to aortitis was successfully performed with aortic no touch technique which consisted of utilization of the left internal thoracic artery, fibrillatory arrest without aortic cross-clamping, left ventricular venting, and femoral artery perfusion. Her postoperative course was uneventful, and she is relieved of angina.

Aged↗