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Effects of salmon calcitonin on growth of teeth and on extraction socket healing in young rats.

The influence of salmon calcitonin on the growth of teeth and alveolar bone, and on the healing of alveolar sockets has been studied in young male rats. The experimental animals received daily injections of salmon calcitonin 0.5 MRC-U/kg body weight, whereas the control group received the vehicle. The rats were sacrificed at 14 and 28 days after the tooth extractions. Salmon calcitonin had no effect on the dry weight, calcium concentration and mineralization of the maxillary molars and the alveolar bone. Neither were there any significant effects of the hormone on the healing alveolar sockets. All sockets were healed after 4 weeks. The mineralization rate of molar teeth was only a quarter of that of tibiae, which was used as a reference.

Alveolar Process↗

Influence of different types of non-resorbable suture material on the healing of extraction wounds--a histological study in rats.

The influence of different non-resorbable suture materials on the healing of tooth extraction wounds was examined in 120 adult male albino rats. Nylon gave the best biological results for healing of the mucosa and dental socket. Silk and cotton produced considerable delay of socket healing. Healing was only mildly delayed by polyester suture, with a short moderate inflammatory reaction at the initial stage.

Alveolar Process↗

Severe hemorrhage from an arteriovenous malformation of the mandible: report of case.

A case of a potentially lethal arteriovenous malformation of the mandibular bone in a 6.5-year-old girl is reported. Diagnosis is often difficult and the AVM may be discovered only when a tooth is extracted. The intent of the preceding report is to alert dental practitioners to the need for immediate control of abnormal bleeding from an extraction socket, because of the potentially lethal consequences. Failure to respond quickly to profuse bleeding of this type could result in the death of the patient by exsanguination.

Arteriovenous Malformations↗

[Comparative histological study of two methods of obtaining alveolar sections in rats].

The chronology of the wound healing process following tooth extraction was studied by means of two kinds of histological cuts. Two groups of 42 albino rats were employed. In the first one, the sockets were cut in a transversal way. In the second one the cuts were performed in a longitudinal way. The rats were sacrificed after 3, 6, 9, 15, 21, 24, and 28 days following the surgeries. After laboratorial outline the obtained pieces were stained by hematoxylin and eosin for histological purposes. It way be concluded that: 1. The results got from longitudinal cuts were in agreement to those described by other authors; 2. The transversal cuts allow us to detect intensive resorption of the lateral alveolar wall at the cervical thirs; 3. On the 21st day following dental extraction the incisor socket of the rat shows a great deal of areas not ossified; 4. The healing process of dental extraction wounds of the upper incisor of the rat is completed between 24 and 28 post operative days.

Alveolar Bone Loss↗

Experimental transplantation of mature molar teeth with and without the supporting structures in mice.

Two types of dental isografts were implanted into the femoral bone of inbred mice: type A, encompassing mature maxillary molars including supporting structure and type B, consisting of the tooth alone. The isografts, together with their host tissues, were examined histologically beginning at day 1 and continuing until day 42 posttransplantation. In both types, the cellular components underwent necrosis with subsequent repopulation of the pulp and periodontal ligament of the graft. A new bony socket formed and partial resorption and ankylosis started on day 10 of transplantation. It is suggested that the host cells present in the periodontal ligament are responsible for the ankylosis and resorption of the tooth root surface.

Animals↗

A radiographic assessment of autologous tooth transplants in dogs.

This study assessed structural and functional changes that occurred when teeth in dogs were transplanted at various stages of development. Unerupted developing permanent teeth were transferred to other existing bony crypts or to surgically prepared bony sockets. Erupted teeth with varying degrees of root formation were transplanted to other sockets, some with increased functional influences. The development, morphologic features, and relationships of the transplanted teeth were assessed radiographically at intervals ranging from seven to 150 days postoperatively.

Animals↗

Clinical studies on diabetes mellitus and diseases of the oral region.

Of the 25,672 patients who visited this clinic between January 1964 and March 1973, 126 were diabetic. These were examined statistically and the following results were obtained. 1. Together with diabetes the following disorders pertaining to the realm of oral surgery were observed: Alveolar pyorrhea (49 cases), infection of oral tissues other than periodontal tissues (24 cases), simple periodontitis (15 cases), tumors (13 cases), dental caries (9 cases), neuralgia (6 cases) and several disorders. 2. Of these 126 cases, 85 needed tooth extraction, which was actually performed in 67 cases with the following results: (a) Of the 67 cases, 13 developed complications such as dry socket, postoperative infection, sequestrum around the extraction socket, etc. This was a significantly higher incidence than in an equal number of controls. (b) In the cases with complications convalescence was prolonged to an average of 54.2 days. (c) In the cases with complications, the preoperative fasting blood sugar level averaged 194.5 mg/dl, which was much higher than in the cases which did not develop complications (average 142.4 mg/dl).

Diabetes Complications↗

An evaluation of 9-aminoacridine/Gelfoam to reduce dry socket formation.

This clinical study was undertaken to evaluate the effectiveness of locally applied 9-aminoacridine in Gelfoam in reducing the incidence of dry socket formation after third molar extractions. Results indicated that this technique was not effective. The incidence of dry socket formation in smokers and nonsmokers was compared. Also, the influence of surgical trauma on dry socket formation was examined.

Aminacrine↗

The influence of closure or dressing of third molar sockets on post-operative swelling and pain.

This study compares the influence of complete closure as opposed to partial closure and dressing of lower third molar sockets on post-operative pain and swelling, and on healing. These closure techniques were used on opposite sides of the mouths of each of 70 patients undergoing bilateral third molar surgery. The comparison of the two techniques within each individual patient showed that complete closure resulted in more pain and swelling post-operatively in a significant number of patients, but that the use of a dressing delayed satisfactory healing in a few patients.

Adult↗

The relationship of "shisha" (water pipe) smoking to postextraction dry socket.

PURPOSE: This study was undertaken to determine whether "shisha" (water pipe) smokers (SS) were at a different risk of developing dry socket (DS) than were cigarette smokers (CS) or nonsmokers (NS) and to assess the effect of preoperative and postoperative smoking habits on the incidence of DS. MATERIALS AND METHODS: One hundred NS, 100 CS, and 100 SS were enrolled. Surgery for removal of mandibular third molars was performed under local anesthesia with no incision or bone removal. At 1, 4, and 7 days after surgery, postoperative evaluation and postoperative smoking were recorded by the same examiner. The chi(2) test was used for statistical analysis of results. Statistical significance was defined as a value of P <.05. RESULTS: Smokers had 2 to 3 times the risk of NS for developing DS. Although SS had a greater incidence of DS than did CS, the difference was not significant (P =.083). The incidence of DS was not age dependent. Smokers who smoked the day of surgery had a significantly higher incidence of DS than did smokers who smoked the second day after surgery. Compared with NS, CS who smoked the day of surgery and SS who smoked the day of surgery or the first day after surgery had a significantly increased incidence of DS (CS/NS, day 0, P =.001; SS/NS, day 0, P =.001; day 1, P =.005). CONCLUSION: SS had 3 times the risk of NS for developing DS, but there was no statistically significant difference between SS and CS. Increased frequency of smoking and smoking during the day of surgery significantly increased the incidence of DS.

Adult↗

Influence of oral hygiene measures on the development of alveolitis sicca dolorosa after surgical removal of mandibular third molars.

This study was carried out in order to investigate the prophylactic effect of plaque control on the development of alveolitis sicca dolorosa (ASD). Sixty patients took part in the investigation. The patients in the test group had their teeth polished 5 days preoperatively and then used a 0.2% aqueous solution of chlorhexidine digluconate as a mouth rinse twice a day before the operation and during the postoperative week. No special oral hygiene measures were taken in the control group. Compared with the control group, the patients in the test group had significantly less plaque on their teeth on the day of operation (P less than or equal to 0.001). One patient in the test group developed ASD, while there were five cases of ASD in the control group. The results indicated that plaque control may be a possible way to decrease the incidence of ASD.

Adult↗

Contemporary views on dry socket (alveolar osteitis): a clinical appraisal of standardization, aetiopathogenesis and management: a critical review.

The objective of this article is to harmonize descriptive definitions for the condition known as alveolar osteitis and to critically review and discuss the aetiology and pathogenesis of alveolar osteitis. In addition, the need for the identification and elimination of risk factors as well as the preventive and symptomatic management of the condition are discussed. The aim of this critical review is to provide a better basis for clinical management of the condition. A meta-analysis of data was not done.

Anti-Infective Agents↗