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[Iron content of human milk and its influence by addition of iron].
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Plasma iron; normal values; response following medication.
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[Photometric microdetermination of the iron-binding capacity of the serum].
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[Research on the biochemistry of the iron in muscle. VI. Nature of muscle iron not contained in the blood; use of radioactive iron in the study of its relation to myosin].
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Iron metabolism in infants. I. The intake of iron in breast feeding and artificial feeding (milk and milk foods).
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[Investigations on the iron metabolism. II. Renal iron excretion in different diseases].
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The effect of different iron preparations on the cells of the reticuloendothelial system.
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[Serum iron in chronic polyarthritis].
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Application of chemical precipitation for piggery wastewater treatment.
Several series of experiments were conducted to investigate the treatment of piggery wastewater using chemical precipitation (CP) where various types of coagulants such as aluminium sulfate (Al2(SO4)3), poly aluminium chloride (PAC), ferric chloride (FeCl3), ferric sulfate (Fe2(SO4)3), ferrous sulfate (FeSO4) and ferrous chloride (FeCl2) were used. Throughout the experiments, CP was found to achieve high removal efficiencies for organic compounds and nutrients (nitrogen and phosphorus) from the piggery wastewater. Experimental results showed the optimal doses of FeCl3, Fe2(SO4)3, FeCl2 and FeSO4 was 2.0 g/L, while 0.31 g/L and 2.5 g/L were the optimum dose for PAC and Al2(SO4)3, respectively. The pH range 4-5 resulted in the best performance to all coagulants except FeCl2 and FeSO4, whose optimum pH were more than 6. Percentage removal efficiencies for COD were in the ranges of 70-80%, 90-95% for SS, 80-90% for organic-N and TP. Those removal efficiencies were achieved within 5 min of operation. Three times of repetition in CP resulted in higher removal efficiencies for COD, SS and colour up to 74%, 99% and 94% respectively, in which Al2(SO4)3 was used as the coagulant. Removal efficiencies of various water quality parameters in a continuously operated reactor were similar to those of the batch experiments. Biodegradable ratios (BOD5/COD) increased up to 65% after the application of CP.
[Data on the hygienic establishment of the maximum permissible concentration of manganese-zinc ferrite in the atmosphere].
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Outer membrane proteins induced under conditions of iron limitation in the marine fish pathogen Vibrio anguillarum 775.
Cells of the marine fish pathogen Vibrio anguillarum 775 harboring a plasmid associated with virulence can grow unaffected in the presence of iron-binding compounds such as transferrin. In contrast, the growth of isogenic plasmidless derivatives is inhibited by the presence of iron chelators. Radioactive from (55Fe3+) uptake experiments indicate that this plasmid-linked ability of V. anguillarum cells to grow under conditions of iron limitation is indeed due to a more rapid and efficient iron uptake mediated by the virulence plasmid. In addition, V. anguillarum cells growing under iron limitation show at least two novel outer membrane proteins. One of them, a 86,000-dalton protein we called OM2, is inducible only in those cells in which the virulence plasmid is present.
Ferrous sulfate poisoning; report of three cases.
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Production of enterochelin by Escherichia coli 0111.
The major neutral iron-transporting compound produced by Escherichia coli 0111/K58/H2 has been isolated from iron-deficient cultures of the organism and compared with the corresponding compound, enterochelin, produced by E. coli K12. The product contained serine and 2,3-dihydroxybenzoic acid and formed a complex with Fe3+. Since the PMR spectra of the products from the two strains were identical, it was concluded that E. coli 0111 also secreted enterochelin under iron-deficient conditions. Although it was not possible to establish the optical configuration of the serine residues in the molecule, the CD spectra of the metal free and Fe3+, complexes were found to be of the same sign and magnitude. The spectra show that metal binding results in considerable conformational changes in the enterochelin molecule. The biological properties of the two compounds appear to be identical as judged by their ability to abolish the bacteriostatic effect of serum on E. coli 0111.
[Exposure to chromium compounds during processing of chromium iron ore].
The work verifies data gathered by Occupational Hygiene departments of Sanitary-Epidemiological Stations about workers exposure to chromium compounds in the processing of chrome iron ore. Research showed that 7 plants were involved in the processing of chrome iron ore and that the number of workers directly employed in the process amounted to 215-230. About 150 workers were exposed to high concentrations of chromium compounds which exceeded hygienic standards. All of them were employed only in metallurgical plants. The remaining 80-100 workers subjected to the study exposed to relatively low chromium concentrations were employed in chemical plants and refractory materials plants.
The role of iron in the growth of human leukemic cell lines.
The growth requirements of three human leukemic cell lines (K 562, HEL, U937) have been studied in the absence of serum. For growth in serum-free medium, the cells require insulin, transferrin, and albumin. Two highly water-soluble iron salts, ferric ammonium citrate and ferric ammonium sulfate, may completely replace transferrin for supporting the growth of these cell lines. Similar results were obtained when mitogen-stimulated lymphocytes were grown in serum-free media. Iron containing compounds, such as hemin or hemoglobin, were also able to replace transferrin. Experiments using 42/6 monoclonal antibody strongly suggest that free-iron salts are taken up by the cells by a mechanism that is completely independent from transferrin-receptors.
The malarial pigment in rat infected erythrocytes and its interaction with chloroquine. A Mössbauer effect study.
Mössbauer studies of rat erythrocytes infected by Plasmodium berghei malaria parasites, using 57Fe-enriched rat red blood cells, were carried out in order to determine the physical parameters which characterize the malarial pigment iron and to test the effect of the widely used antimalaria drug, chloroquine, on these parameters. The iron in the malarial pigment which is derived from hemoglobin digestion by the intracellular parasite was found to be trivalent, high spin, with Mössbauer parameters which are significantly different from those of any known iron porphyrin containing compound. No difference was found between the parameters obtained in erythrocytes infected by drug-sensitive and drug-resistant strains of P. berghei, both before and after the treatment with chloroquine. The iron compound consists of microaggregates, about 30 A in diameter. These are somewhat larger in chloroquine-resistant strains and tend to increase in size in chloroquine-sensitive strains upon treatment with the drug. Mössbauer spectra of erythrocytes infected by a chloroquine-resistant strain revealed pigment iron in relative amounts invariable of those found in chloroquine-sensitive strains, demonstrating that drug-resistant parasites indeed digest hemoglobin.
Ferroverdin, a green pigment containing iron produced by a streptomycete.
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