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At least 991 records · Page 55Linked to original sources
PubMed1985

Cysteamine-induced duodenal ulcer is not site-specific: effect of local modulating factors.

In cysteamine-induced duodenal ulcer, an animal model for the clinical disease, lesions are characteristically produced on the anterior and posterior walls of the proximal duodenum. Using this model, we investigated factors that may affect duodenal ulcer localization and intensity. Mobilization of the gastroduodenum by severing its ligaments; circumscribed application of acetic acid to the serosa of the lateral wall of the duodenum; or placement of materials (e.g., gelfoam, parafilm) on the proximal duodenum, each decreased the intensity of anterior-posterior ulcers and resulted in formation of atypical, mostly distal duodenal ulcers. The effect of these manipulations on acid secretion suggests that their influence on the development of duodenal ulcer is not entirely due to modulation of gastric secretion. The data indicate that the localization of induced duodenal ulcer can be shifted distally and is therefore not site specific. This study provides new clues and techniques for the study of the pathogenesis of duodenal ulcer disease.

Acetates↗
PubMed1985

Percutaneous transcatheter embolization for arterial trauma.

With increasing technologic advances in interventional radiology, the vascular surgeon should be well versed in the indications, limitations, complications, and results of percutaneous transcatheter embolization for arterial trauma. Three hundred twenty-eight angiographically determined arterial injuries occurred in 242 patients from 1977 to 1984 in a major city hospital trauma center and were studied prospectively. Transcatheter embolizations performed for 107 arterial injuries in 100 patients were successful in 82.2% of injuries. Gelfoam, minicoils, microcoils, intimal dissections, or a combination of modalities was utilized. Anterior and posterior element pelvic fractures associated with hypotension and transfusion of 6 units or more of blood required embolization in 28 patients. Bleeding was controlled in 85.7% of patients. Percutaneous transcatheter embolization was also effective in controlling 84.2% of arteriovenous fistulas, 88.9% of penetrating neck arterial injuries, and 73.3% of postoperative intra-abdominal hemorrhage. Therapeutic transcatheter embolization is a valuable adjunct to the vascular surgeon dealing with the spectrum of vascular trauma.

Arteries↗
PubMed1985

[The use of fibrin glue in neurosurgical operations].

Fibrin glue has been used in 22 neurosurgical patients and following five effects which are very much helpful in neurosurgical practice were recognized. Adhesive effect--Dural defect at cranial base was closed with lyophilized dura and fibrin glue. Hemostatic effect--Fibrin glue soaked oxycel was applied for hemostasis of the bleeding from venous sinus, dura, skull edge and cut surface of tumor. Blocking and sealing effects--In cases of craniopharyngioma, cyst wall around the inserted tube was sealed with oxycel and fibrin glue. CSF leakage from open sphenoidal sinus in aneurysmal operation was closed with fibrin glue soaked gelfoam. Covering and wall strengthening effects--Unclippable aneurysms were coated and wrapped with fibrin glue and oxycel. Packing effect--Huge dead space after removal of mucocele was packed with fibrin glue. In trans-sphenoidal operation of pituitary adenoma, fibrin glue soaked muscle pieces and oxycel were packed in the dead space and sphenoidal sinus. Many other possible availabilities in neurosurgical operations were discussed. Fibrin glue is a biological product, so it can be used with more safety and affinity to the local tissue and with less reaction as foreign body than the artificial adhesives. It takes much time for the preparation of this material for the time being. If this can be prepared instantly, usefulness of this glue will be markedly increased. We have had no hepatitis nor inflammatory complications in our limited experience.

Adolescent↗
PubMed1986

[Significance of temporary injection into the lining of the vocal cords in the treatment of paralytic dysphonia].

We report on our clinical experience with the so-called temporary injection of the vocal cords by means of gelatin paste (Gelfoam) application, performed on 24 patients. In a fairly high percentage of patients we noted a long-lasting positive result in respect of vocal performance, despite persisting vocal cord paresis. It is believed that in such cases the relatively slow absorption of the gelatin paste creates favourable conditions for spontaneous phonatory compensation.

Follow-Up Studies↗
PubMedDate not supplied

The safety of cement fixation in the cervical spine. Studies of a rabbit model.

Immediate postoperative ambulation of patients with terminal neoplastic disease of the cervical spine can be permitted by vertebral stabilization with wire reinforced with polymethylmethacrylate. Precautions are necessary to avoid a temperature rise during cement polymerization and prevent vasular or nerve damage. Experiments on 20 rabbits and 2 human cadavers indicate that temperature at the cement-lamina interface can rise as high as 90 degrees while temperature under the intact lamina measures only 50 degrees. Precooling and insulation with Gelfoam may prevent heat injury to spinal cord.

Animals↗
PubMed1979

Excisional arthroplasty of the elbow.

Thirty patients had excisional arthroplasty of the elbow, with interpositional Gelfoam and early mobilization. Most of the patients had residual disability from trauma. Most of the patients' results were evaluated four years or more after the operation: 80 per cent were pain-free and 90 per cent were able to return to their previous occupations. One patient had to be reoperated on and therefore was considered to have a poor result.

Adolescent↗
PubMed1979

Transcatheter embolization of bronchial collateral arteries prior to intracardiac operation for tetralogy of Fallot.

In a case of tetralogy of Fallot with numerous bronchial collateral arteries (BCA), the collateral arteries were successfully occluded by transcatheter embolization of Gelfoam and use of the Gianturco spring as a preliminary to intracardiac repair. Pulmonary embolism would not result from this procedure in the absence of large direct communications between collateral and pulmonary arteries. The femoral artery and vein were prepared for cannulation before the procedure, so that it would be possible to start assisted perfusion immediately if arterial PO2 fell after transcatheter embolization. The procedure is performed under fluoroscopic control.

Adult↗
PubMed1977

Selective arterial embolization for hemorrhage following hip arthroplasty.

A case is presented in which selective embolization of gelfoam was used to control late postoperative bleeding, developing in a patient following hip arthroplasty. Although primarily used in gastrointestinal bleeding, diagnostic and therapeutic angiography, selective embolization is clearly applicable to postoperative bleeding encountered in orthopedics.

Arteries↗
PubMed1977

[Comparison between two current methods of surgical treatment for otosclerosis].

Statistical comparison is established between two methods of stapedectomy, the first one being the "Teflon-interposition", the second being Schuknecht's method (gelfoam and preformed wire). There is statistical evidence that the Teflon-interposition method is better. The results are also compared with those of other workers.

Adult↗
PubMed1980

[Arterial transcatheter embolization in arterio-venous fistulae therapy (aithor's transl)].

In arterio-venous malformations, arterial trans-catheter embolization can be considered as a definitive treatment, a pre-operative devascularizing technique, and a palliative treatment of those not surgically operable malformations. A very important point is choosing the correct way where to introduce the catheter and the embolizing devices. The most known devices are: synthetic fibrin foam (Gelfoam, Spongostan), Gianturco coils, and among the non reabsorbable devices a polyvinylic alcohol foam (Ivalon), the isobutyl-2-cyanoacrylate and silicone. Furthermore detachable balloons and bristle-brushes can be used. Many parameters must be taken into consideration: hemodynamic fluxes of the lesion, type of vascularization, extension of the lesion, aim of the embolization, possible risks. When embolizing large territories, the protocol must foresee several performances for the control of the embolized vessels, the presence of collateral circulation, the extension of the embolization and other afferent arteries to the lesion. Regarding the permanent occlusions it is preferable to utilize fragments of Ivalon, small silicone spheres or liquid silicone; finally, reabsorbable device must be used in the distal embolizations and non reabsorptible in the proximal embolizations. The best results have been achieved in the traumatic lesions where a direct communication exists between an artery and a vein. Among the arterio-venous malformations the best results have been achieved in cranio-facial angiomas with low flux. The possible complications are consequences of ischemia: necrotic musculo-cutaneous, cerebral or troncular changes.

Adult↗
PubMed1984

[Kidney tumor embolization. Progress, experiences and complications].

Indications for preoperative and palliative embolization of renal tumors have been restricted due to the failures caused by insufficient tumor blockage. Personal experiences using a variety of materials (balloon n = 18, gelfoam n = 10, ethibloc1 /glucose n = 23) and their effectiveness are presented. special emphasis is placed on the influence of parasitic collaterals and the complication rate on the various procedures. Clinical results corroborate those obtained from our own animal experiments: only a capillary embolization that is based on the tumor volume exhausts the current possibilities of therapeutic vascular occlusion of tumors.

Diatrizoate↗
PubMed1978

Renovascular hypertension following surgical repair of dissecting aneurysm of the thoracic aorta.

A critically ill patient with refractory renovascular hypertension following successful intrathoracic repair of a type I aortic dissection was treated successfully with gelfoam embolization of the left kidney. Renal artery stenosis secondary to aortic dissection can exacerbate pre-existent hypertension in the preoperative or postoperative periods and can be diagnosed angiographically. Unilateral renal artery embolization may provide a safe alternative to nephrectomy for renovascular hypertension in cases where surgery is not feasible.

Aortic Dissection↗
PubMed1980

[Renal embolisation, renal cystography and percutaneous nephrostomy (author's transl)].

In renal disease, therapeutic procedures performed by radiologists include embolisation, cystography with obliteration and percutaneous nephrostomy. More than 72 therapeutic occlusions of the renal artery by balloon, coil, and gelfoam are presented. Basic differences in technique of application and in the mechanism of Ethibloc in comparison to other kinds of embolisation material are pointed out. In 61 diagnostic punctures of renal cysts, guided by sonograpny, 31 were treated by injection of Lipiodol. As in cystography, the combination of sonography and radiology proved to be highly valuable in 37 percutaneous nephrostomies. Technique, indication, contraindication, and complication of renal embolisation, renal cystography and percutaneous nephrostomy are briefly discussed.

Adenocarcinoma↗
PubMed1980

[Scanning electron microscopy of human cultured gliomas (author's transl)].

Tumor tissues of glioblastoma multiforme, astrocytoma and medulloblastoma, maintained up to 21--28 days by gelfoam organ culture technique, were examined by scanning electron microscopy (SEM). Glioblastoma multiform has irregular cell surface and many cytoplasmic folds. Astrocytoma has many fibrils. The fibrils have smooth surface and are coiling. Fibrils of piloid astrocytoma are smooth and cylindrical. The focal thickness of fibrils are associated with so-called Rosenthal fiber. Capillary of astrocytoma has irregular surface and marked tortuosity. Medulloblastoma is composed of non-fibrillated round tumor cells. The tumor cells touch each other with short cell processes. These findings seemed to correspond to the malignancy of original tumor. Comparative observation of medulloblastoma maintained by monolayer cell culture with one maintained by organ culture, using light microscopy and scanning electron microscopy, was done. And medulloblastoma in monolayer culture was proliferated to two types of cells. One is epitheloid cell with taper cell processes, and the other is stellate cell with fine processes. In most organ culture, feature of cells corresponded to those observed in original surgical material by light microscopy.

Astrocytoma↗
PubMedDate not supplied

Radiographic management of juvenile angiofibromas.

Juvenile angiofibromas are benign, vascular, locally aggressive neoplasms that are preferably treated by surgical resection, or irradiation if surgery is not possible. Adequate surgery in the past has been limited by incomplete knowledge of the anatomy of the tumor and technical difficulties related to the vascularity. To better define the tumor, 12 patients with juvenile angiofibroma have been studied by axial and coronal high resolution computed tomography (CT). The extent of the neoplasm was better demonstrated by CT than by other techniques. Based on the CT findings, we propose an anatomic classification that is helpful in determining treatment methods. Nine patients were considered operable, and eight of these underwent preoperative embolization with Silastic spheres and Gelfoam. The preoperative embolization significantly reduced operative difficulty and the necessity for blood transfusions. Based on these cases, we believe the current radiographic management of juvenile angiofibromas should consist of plain films, CT, angiography and, in surgical cases, preoperative embolization.

Adolescent↗
PubMed1981

[Interventional neuroradiology. I. Cranio-facial embolisations (author's transl)].

Technical and methodological procedures as well as results and follow-up studies of superselective angiographies and embolisations with different materials (gelfoam, lyophilised dura, silicone-elastomer) in 105 patients with vascular lesions (arteriovenous angiomas and fistulas, capillary haemangiomas), benign (glomus tumors, fibromas, meningeomas) and malignant tumors (sarcomas, metastases) of the cranio-facial region are described. Due to the clinical findings and follow-up studies up to three years there were different palliative and curative results which are exemplified. Therefore, a uniform performance of the embolisatory interventions is refused. The arterial approach, the different catheter systems as well as the actual technical procedure of the embolisations, with or without superselective pharmacoangiographies, has to be chosen according to the individual manifestation of the lesions and their anatomical and pathological conditions.

Cerebral Angiography↗
PubMed1983

[Complication of therapeutic transcatheter hepatic artery embolization for hepatoma--case of developing an extensive acute gastric ulcer].

We report the development of an extensive acute gastric ulcer in a 60-year-old man following therapeutic transcatheter hepatic artery embolization for hepatoma. The unintentional occlusion of branches of the right gastric artery with refluxed Gelfoam fragments is thought to be responsible. This complication is probably rare, but should be kept in mind when therapeutic embolization of the hepatic artery is performed.

Acute Disease↗
PubMed1983

[Deep lesion of the femoral artery and fracture of the femoral diaphysis. Value of selective embolization].

The authors report a case of an osteosynthesized fracture of the femoral shaft with a lesion of the deep femoral artery revealed at a late stage by sudden appearance of a hematoma. A diagnostic arteriogram was performed, followed by therapeutic embolization: temporary hemostasis was achieved by the hyper-selective injection of Gelfoam, thus allowing anti-coagulant therapy for associated venous thrombosis to be continued, without abnormal delay in bone consolidation.

Adult↗